ATE234321T1 - Zwischenprodukte und verfahren um aus diesen ein makrolid-antibiotium herzustellen - Google Patents

Zwischenprodukte und verfahren um aus diesen ein makrolid-antibiotium herzustellen

Info

Publication number
ATE234321T1
ATE234321T1 AT99958490T AT99958490T ATE234321T1 AT E234321 T1 ATE234321 T1 AT E234321T1 AT 99958490 T AT99958490 T AT 99958490T AT 99958490 T AT99958490 T AT 99958490T AT E234321 T1 ATE234321 T1 AT E234321T1
Authority
AT
Austria
Prior art keywords
antibiotium
macrolide
processes
producing
intermediate products
Prior art date
Application number
AT99958490T
Other languages
English (en)
Inventor
Tae Suk Lee
Chang Hyun Yoo
Kyoung Soo Kim
Hyun Suk An
Jung Young Kim
Wan Joo Kim
Original Assignee
Chemtech Res Inc
Hansol Chemience Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chemtech Res Inc, Hansol Chemience Co Ltd filed Critical Chemtech Res Inc
Application granted granted Critical
Publication of ATE234321T1 publication Critical patent/ATE234321T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT99958490T 1998-11-24 1999-11-24 Zwischenprodukte und verfahren um aus diesen ein makrolid-antibiotium herzustellen ATE234321T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR19980050425 1998-11-24
KR1019990050802A KR100317907B1 (ko) 1998-11-24 1999-11-16 신규한 중간체, 이를 이용한 마크로라이드계 항생제의제조방법
PCT/KR1999/000708 WO2000031099A1 (en) 1998-11-24 1999-11-24 Novel intermediates, process for preparing macrolide antibiotic agent therefrom

Publications (1)

Publication Number Publication Date
ATE234321T1 true ATE234321T1 (de) 2003-03-15

Family

ID=26634358

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99958490T ATE234321T1 (de) 1998-11-24 1999-11-24 Zwischenprodukte und verfahren um aus diesen ein makrolid-antibiotium herzustellen

Country Status (21)

Country Link
US (1) US6600025B1 (de)
EP (1) EP1133511B1 (de)
JP (1) JP3848837B2 (de)
KR (1) KR100317907B1 (de)
CN (1) CN1354753A (de)
AT (1) ATE234321T1 (de)
AU (1) AU751874B2 (de)
BR (1) BR9915646A (de)
CA (1) CA2352162A1 (de)
CZ (1) CZ20011803A3 (de)
DE (1) DE69905935T2 (de)
DK (1) DK1133511T3 (de)
ES (1) ES2190275T3 (de)
HU (1) HUP0104600A3 (de)
IL (1) IL143331A0 (de)
MX (1) MXPA01005248A (de)
PL (1) PL348607A1 (de)
PT (1) PT1133511E (de)
RU (1) RU2208615C2 (de)
TR (1) TR200101474T2 (de)
WO (1) WO2000031099A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2552682T3 (es) 2003-03-10 2015-12-01 Merck Sharp & Dohme Corp. Agentes antibacterianos novedosos
ES2221807B1 (es) * 2003-06-24 2005-12-16 Ercros Industrial, S.A. Un procedimiento para la obtencion de claritromicina.
US7767797B1 (en) * 2004-09-30 2010-08-03 Synovo Gmbh Macrocyclic compounds and methods of use thereof
US7582611B2 (en) * 2005-05-24 2009-09-01 Pfizer Inc. Motilide compounds
CA2614412A1 (en) * 2005-07-07 2007-01-18 Elan Pharma International, Limited Nanoparticulate clarithromycin formulations
US20090054634A1 (en) * 2007-08-09 2009-02-26 Vinod Kumar Kansal Process for the preparation of clarithromycin
WO2009055557A1 (en) 2007-10-25 2009-04-30 Cempra Pharmaceuticals, Inc. Process for the preparation of macrolide antibacterial agents
WO2010048601A1 (en) 2008-10-24 2010-04-29 Cempra Pharmaceuticals, Inc. Biodefenses using triazole-containing macrolides
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
AU2010292010B2 (en) 2009-09-10 2016-01-07 Cempra Pharmaceuticals, Inc. Methods for treating malaria, tuberculosis and MAC diseases
SI2550286T1 (sl) 2010-03-22 2016-04-29 Cempra Pharmaceuticals, Inc. Kristalne oblike makrolida in njihove uporabe
RU2608390C2 (ru) 2010-05-20 2017-01-18 Семпра Фармасьютикалз, Инк. Способы получения макролидов и кетолидов, и промежуточных соединений для их получения
JP6042334B2 (ja) 2010-09-10 2016-12-14 センプラ ファーマシューティカルズ，インコーポレイテッド 疾患治療のための水素結合形成フルオロケトライド
RU2658050C2 (ru) 2012-03-27 2018-06-19 Семпра Фармасьютикалз, Инк. Парентеральные составы для введения макролидных антибиотиков
US9861616B2 (en) 2013-03-14 2018-01-09 Cempra Pharmaceuticals, Inc. Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh) 2013-03-15 2015-12-23 森普拉制药公司 用于制备大环内酯抗菌剂的收敛方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5872229A (en) * 1995-11-21 1999-02-16 Abbott Laboratories Process for 6-O-alkylation of erythromycin derivatives
US5719272A (en) * 1996-04-02 1998-02-17 Abbott Laboratories 2'-protected 3'-dimethylamine, 9-etheroxime erythromycin A derivatives
US5864023A (en) * 1997-02-13 1999-01-26 Abbott Laboratories 3'-N'oxide, 3'-n-dimethylamine, 9-oxime erythromycin a derivatives
US5929219A (en) * 1997-09-10 1999-07-27 Abbott Laboratories 9-hydrazone and 9-azine erythromycin derivatives and a process of making the same
EP1036084A1 (de) * 1997-12-01 2000-09-20 Abbott Laboratories Chemische synthese von 6-o-alkyl erythromycin c
WO1999032500A2 (en) * 1997-12-22 1999-07-01 Biochemie S.A. Intermediates in macrolide production
AU2658899A (en) * 1998-02-04 1999-08-23 Teva Pharmaceutical Industries Ltd. Process for making clarithromycin

Also Published As

Publication number Publication date
DE69905935D1 (de) 2003-04-17
ES2190275T3 (es) 2003-07-16
CZ20011803A3 (cs) 2001-10-17
IL143331A0 (en) 2002-04-21
US6600025B1 (en) 2003-07-29
DE69905935T2 (de) 2003-09-04
KR100317907B1 (ko) 2001-12-24
PT1133511E (pt) 2003-06-30
RU2208615C2 (ru) 2003-07-20
AU1584700A (en) 2000-06-13
EP1133511B1 (de) 2003-03-12
HUP0104600A2 (hu) 2002-03-28
PL348607A1 (en) 2002-06-03
AU751874B2 (en) 2002-08-29
WO2000031099A1 (en) 2000-06-02
JP2002530423A (ja) 2002-09-17
TR200101474T2 (tr) 2001-12-21
MXPA01005248A (es) 2003-08-19
BR9915646A (pt) 2001-08-07
DK1133511T3 (da) 2003-07-14
CN1354753A (zh) 2002-06-19
CA2352162A1 (en) 2000-06-02
HUP0104600A3 (en) 2003-12-29
KR20000057013A (ko) 2000-09-15
EP1133511A1 (de) 2001-09-19
JP3848837B2 (ja) 2006-11-22

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties