ATE233724T1 - Cyclohexenon langketten alkohol und diese enthaltendes arzneimittel - Google Patents
Cyclohexenon langketten alkohol und diese enthaltendes arzneimittelInfo
- Publication number
- ATE233724T1 ATE233724T1 AT98936726T AT98936726T ATE233724T1 AT E233724 T1 ATE233724 T1 AT E233724T1 AT 98936726 T AT98936726 T AT 98936726T AT 98936726 T AT98936726 T AT 98936726T AT E233724 T1 ATE233724 T1 AT E233724T1
- Authority
- AT
- Austria
- Prior art keywords
- chain alcohol
- long chain
- products containing
- containing same
- medicinal products
- Prior art date
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 title abstract 3
- FWFSEYBSWVRWGL-UHFFFAOYSA-N cyclohex-2-enone Chemical compound O=C1CCCC=C1 FWFSEYBSWVRWGL-UHFFFAOYSA-N 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- JHIVVAPYMSGYDF-UHFFFAOYSA-N cyclohexanone Chemical compound O=C1CCCCC1 JHIVVAPYMSGYDF-UHFFFAOYSA-N 0.000 abstract 2
- 208000024827 Alzheimer disease Diseases 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000014511 neuron projection development Effects 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
- C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/713—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP21847497 | 1997-08-13 | ||
| PCT/JP1998/003560 WO1999008987A1 (en) | 1997-08-13 | 1998-08-11 | Cyclohexenone long-chain alcohol and medicament containing same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE233724T1 true ATE233724T1 (de) | 2003-03-15 |
Family
ID=16720502
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98936726T ATE233724T1 (de) | 1997-08-13 | 1998-08-11 | Cyclohexenon langketten alkohol und diese enthaltendes arzneimittel |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6228893B1 (enExample) |
| EP (1) | EP1003706B1 (enExample) |
| JP (1) | JP3766591B2 (enExample) |
| AT (1) | ATE233724T1 (enExample) |
| CA (1) | CA2299308C (enExample) |
| DE (1) | DE69811905T2 (enExample) |
| WO (1) | WO1999008987A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4469441B2 (ja) | 1999-02-10 | 2010-05-26 | 明治乳業株式会社 | 神経変性疾患の予防又は治療薬 |
| JP4490536B2 (ja) * | 2000-01-31 | 2010-06-30 | 明治乳業株式会社 | 脳血管障害に基づく疾患の予防又は治療薬 |
| JP2002068973A (ja) * | 2000-06-16 | 2002-03-08 | Meiji Milk Prod Co Ltd | 幹細胞分化誘導促進剤 |
| US20040115810A1 (en) * | 2000-10-04 | 2004-06-17 | Bang Luu | Stem cell differentiation-inducing promoter |
| JP4250882B2 (ja) * | 2000-10-18 | 2009-04-08 | 住友化学株式会社 | スルホン誘導体およびその製造方法 |
| JP4861560B2 (ja) * | 2001-02-19 | 2012-01-25 | 株式会社明治 | 糖尿病合併症治療剤 |
| JP3836684B2 (ja) * | 2001-02-19 | 2006-10-25 | 明治乳業株式会社 | 排尿障害治療剤 |
| WO2002094252A1 (en) * | 2001-05-24 | 2002-11-28 | Meiji Dairies Corporation | Preventive or remedy for diseases caused by cerebrovascular disturbances |
| JP2005518403A (ja) * | 2002-01-09 | 2005-06-23 | トリデント サイエンシーズ エルエルシー | アンドロゲンレセプターをブロックする化合物 |
| JP4035332B2 (ja) * | 2002-01-22 | 2008-01-23 | 明治乳業株式会社 | シクロヘキセノン長鎖アルコールの製造法 |
| US7307098B2 (en) | 2002-07-19 | 2007-12-11 | Meiji Dairies Corporation | Indole derivatives and drugs containing the same |
| CA2519178C (en) | 2003-03-28 | 2010-01-12 | Meiji Dairies Corporation | Process for producing cyclohexenone long-chain alcohols |
| CA2583699C (en) * | 2004-10-13 | 2012-11-20 | Meiji Dairies Corporation | Stat3 phosphorylation inhibitor and notch1 expression inhibitor |
| CN101180041B (zh) * | 2005-01-18 | 2011-04-13 | 明治乳业株式会社 | 感觉障碍治疗剂 |
| EP1854777A4 (en) * | 2005-02-28 | 2010-07-07 | Meiji Dairies Corp | LONG-CHAINED HYDROCHINONE DERIVATIVE AND / OR LONG-CHAINED PHENOXY DERIVATIVE AND PHARMACEUTICAL PREPARATION CONTAINING THEREOF |
| US20080312336A1 (en) * | 2005-05-26 | 2008-12-18 | Keisuke Satoh | Preventive and/or Therapeutic Agent for Diabetic Vascular Disorder and Respiratory Disorder |
| WO2013147072A1 (ja) * | 2012-03-29 | 2013-10-03 | 大鵬薬品工業株式会社 | 3-(15-ヒドロキシペンタデシル)-2,4,4-トリメチル-2-シクロヘキセン-1-オンの共結晶 |
| JP5566521B1 (ja) | 2013-09-27 | 2014-08-06 | 大鵬薬品工業株式会社 | 膀胱・尿道協調不全改善剤 |
| US20170035705A1 (en) * | 2015-08-04 | 2017-02-09 | Taiho Pharmaceutical Co., Ltd. | Detrusor hyperactivity with impaired contractility ameliorating agent |
| BR112018014841B1 (pt) | 2016-01-22 | 2022-03-03 | Taiho Pharmaceutical Co., Ltd. | Álcoois de cadeia longa cicloexenona, seus usos e métodos para a produção dos mesmos com alta pureza |
| JP2022013721A (ja) | 2020-07-03 | 2022-01-18 | 大鵬薬品工業株式会社 | 排尿症状治療剤 |
| US20230295068A1 (en) * | 2020-08-07 | 2023-09-21 | Taiho Pharmaceutical Co., Ltd. | Novel cycloalkenone compound or salt thereof |
| US20250178998A1 (en) | 2022-02-09 | 2025-06-05 | Taiho Pharmaceutical Co., Ltd. | Crystal form of cyclohexenone compound |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0448697B1 (fr) * | 1989-10-13 | 1996-04-10 | Neurofit | Analogues de la vitamine a, leurs applications, notamment en tant que molecules cytotrophiques et cytoprotectrices, et compositions pharmaceutiques les contenant |
| ATE105282T1 (de) * | 1992-11-18 | 1994-05-15 | Medafor | Langkettige fettalkohole mit neurotropischer und gedaechtnissfoerdernder wirkung. |
-
1998
- 1998-08-11 DE DE69811905T patent/DE69811905T2/de not_active Expired - Lifetime
- 1998-08-11 JP JP2000509675A patent/JP3766591B2/ja not_active Expired - Lifetime
- 1998-08-11 EP EP98936726A patent/EP1003706B1/en not_active Expired - Lifetime
- 1998-08-11 US US09/463,972 patent/US6228893B1/en not_active Expired - Lifetime
- 1998-08-11 AT AT98936726T patent/ATE233724T1/de not_active IP Right Cessation
- 1998-08-11 CA CA002299308A patent/CA2299308C/en not_active Expired - Lifetime
- 1998-08-11 WO PCT/JP1998/003560 patent/WO1999008987A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP3766591B2 (ja) | 2006-04-12 |
| DE69811905T2 (de) | 2003-11-06 |
| WO1999008987A1 (en) | 1999-02-25 |
| EP1003706A1 (en) | 2000-05-31 |
| DE69811905D1 (de) | 2003-04-10 |
| CA2299308C (en) | 2008-03-25 |
| US6228893B1 (en) | 2001-05-08 |
| JP2001515058A (ja) | 2001-09-18 |
| EP1003706B1 (en) | 2003-03-05 |
| CA2299308A1 (en) | 1999-02-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |