DE69320367D1 - Therapeutische verbindungen für die behandlung von krankheiten, die mit einem glutathion-defizit assoziiert sind, herstellungsprozess und diese enthaltene pharmazeutische zusammensetzungen - Google Patents

Therapeutische verbindungen für die behandlung von krankheiten, die mit einem glutathion-defizit assoziiert sind, herstellungsprozess und diese enthaltene pharmazeutische zusammensetzungen

Info

Publication number
DE69320367D1
DE69320367D1 DE69320367T DE69320367T DE69320367D1 DE 69320367 D1 DE69320367 D1 DE 69320367D1 DE 69320367 T DE69320367 T DE 69320367T DE 69320367 T DE69320367 T DE 69320367T DE 69320367 D1 DE69320367 D1 DE 69320367D1
Authority
DE
Germany
Prior art keywords
treatment
pharmaceutical compositions
pct
compositions containing
glutathion
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69320367T
Other languages
English (en)
Other versions
DE69320367T2 (de
Inventor
Lorenzo Ferrari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prospa NV
Original Assignee
Prospa NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prospa NV filed Critical Prospa NV
Application granted granted Critical
Publication of DE69320367D1 publication Critical patent/DE69320367D1/de
Publication of DE69320367T2 publication Critical patent/DE69320367T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69320367T 1992-11-30 1993-11-30 Therapeutische verbindungen für die behandlung von krankheiten, die mit einem glutathion-defizit assoziiert sind, herstellungsprozess und diese enthaltene pharmazeutische zusammensetzungen Expired - Fee Related DE69320367T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI922742A IT1256178B (it) 1992-11-30 1992-11-30 Composti ad attivita' terapeutica utili per il trattamento di malattieconnesse ad una carenza di glutatione, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono.
PCT/EP1993/003354 WO1994012527A1 (en) 1992-11-30 1993-11-30 Therapeutic compounds suitable for the treatment of diseases connected with glutathione deficiency, process for their preparation, and pharmaceutical compositions containing same

Publications (2)

Publication Number Publication Date
DE69320367D1 true DE69320367D1 (de) 1998-09-17
DE69320367T2 DE69320367T2 (de) 1998-12-17

Family

ID=11364384

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69320367T Expired - Fee Related DE69320367T2 (de) 1992-11-30 1993-11-30 Therapeutische verbindungen für die behandlung von krankheiten, die mit einem glutathion-defizit assoziiert sind, herstellungsprozess und diese enthaltene pharmazeutische zusammensetzungen

Country Status (8)

Country Link
US (1) US5736565A (de)
EP (1) EP0674653B1 (de)
AT (1) ATE169635T1 (de)
CA (1) CA2150548A1 (de)
DE (1) DE69320367T2 (de)
ES (1) ES2122221T3 (de)
IT (1) IT1256178B (de)
WO (1) WO1994012527A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6420429B1 (en) * 1997-12-23 2002-07-16 Yissum Research Development Company Of The Hebrew University Of Jerusalem Brain targeted low molecular weight hydrophobic antioxidant compounds
US6369106B1 (en) 1996-12-26 2002-04-09 Yissum Research Development Company Of The Hebrew University Of Jerusalem Treatment of ischemic brain injuries with brain targeted anti oxidant compounds
AU728488B2 (en) 1997-04-02 2001-01-11 Sankyo Company Limited Dithiolan derivatives, their preparation and their therapeutic effect
AU758155B2 (en) 1998-04-29 2003-03-13 Oklahoma Medical Research Foundation Construction of retroviral producer cells from adenoviral and retroviral vectors
US7407986B2 (en) * 2001-12-18 2008-08-05 Brassica Foundation For Chemoprotection Research, Inc. Prevention and treatment of oxidative stress disorders by glutathione and phase II detoxification enzymes
JP4520089B2 (ja) * 2002-05-31 2010-08-04 サントリーホールディングス株式会社 ルブロフサリン配糖体含有組成物
EP1946750A1 (de) * 2007-01-18 2008-07-23 The Jordanian Pharmaceutical Manufacturing Co. Kopräzipitat, Herstellungsverfahren und Anwendungen davon
CN101687909B (zh) * 2007-03-23 2013-12-18 日清药业股份有限公司 预防或治疗肝脏疾病的组合物
KR20110060940A (ko) * 2008-09-22 2011-06-08 닛신 파마 가부시키가이샤 항염증성 펩티드

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT40447A (en) * 1984-03-29 1986-12-28 Sandoz Ag Process for preparing substituted alpha-amino acids and pharmaceutical compositions containing such compounds
IT1216096B (it) * 1988-03-15 1990-02-22 Farmaceutica Italiana S P A S L_piroglutamil_l_cisteina, dipeptide ad elevata attivita'anticatarattogena e composizioni farmaceutiche che lo contengono.
IT1244548B (it) * 1991-02-06 1994-07-15 Poli Ind Chimica Spa Derivati della 5-oxo-l-prolina e loro applicazioni farmaceutiche
IT1249650B (it) * 1991-05-29 1995-03-09 Poli Ind Chimica Spa N-(5-tioxo-l-prolil)-l-cisteina e suoi derivati, loro preparazione ed impiego terapeutico

Also Published As

Publication number Publication date
CA2150548A1 (en) 1994-06-09
ATE169635T1 (de) 1998-08-15
ES2122221T3 (es) 1998-12-16
ITMI922742A0 (it) 1992-11-30
ITMI922742A1 (it) 1994-05-30
EP0674653A1 (de) 1995-10-04
DE69320367T2 (de) 1998-12-17
IT1256178B (it) 1995-11-29
EP0674653B1 (de) 1998-08-12
WO1994012527A1 (en) 1994-06-09
US5736565A (en) 1998-04-07

Similar Documents

Publication Publication Date Title
DK0447285T3 (da) Nephtalenderivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler indeholdende dem
HUP0000383A2 (hu) Tetrahidro-kinoxalinil-(amino-alkil)-foszfonsavak, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények
DE69613365T2 (de) Ester der 5-aminolevulinsäure als mittel zur photosensibilisierung in der chemotherapie
UA27901C2 (uk) Похідні 7-(2-аміноетил)бензотіазолону, що проявляють агоністичну активність по відношенню до бета2-адренорецепторів, фармацевтична композиція, спосіб їх отримання та проміжні сполуки
DE69320367D1 (de) Therapeutische verbindungen für die behandlung von krankheiten, die mit einem glutathion-defizit assoziiert sind, herstellungsprozess und diese enthaltene pharmazeutische zusammensetzungen
ES2111352T3 (es) Uso de diester fosfato para el tratamiento de enfermedades retinianas.
ATE85334T1 (de) Bisphenylalkylpiperazin-derivate, verfahren zur herstellung und arzneimittelzubereitung.
DE69103630D1 (de) Oxazolederivate, ihre herstellung und diese enthaltende pharmazeutischen zubereitungen.
DE69512208D1 (de) Aminosäurederivate und ihre verwendung als phospholipase-a2-inhibitoren
DE69315836T2 (de) Pyrazolpyridine für die behandlung der anämie
ES2028838T3 (es) Procedimiento para la obtencion de nuevos derivados de 4,5-hidro-oxazoles.
DE69400704D1 (de) N-acylpyrrolidine und arzneimittel zur behandlung oder prophylaxe von mit ckk und gastrin in zusammenhang stehenden krankheiten
ATE110568T1 (de) Pharmazeutisches präparat zur behandlung des katarakts.
FR2700165B1 (fr) Dérivés de pyrrolidine, leur préparation et les médicaments les contenant.
HU9503099D0 (en) New piperazinyl-alkylthio-pyrimidine derivatives, pharmaceutical compositions containing them, and process for producing the active components
MY103293A (en) N-imidazolyl derivatives of bicyclic compounds useful in medicine
SE9202218D0 (sv) Pharmacologically active alfa-(tertiary-aminomethyl)-benzenemethanol derivatives, pharmaceutical composition containing them, therapeutical use thereof and processes for their preparation
KR950702566A (ko) 사슬형 아미딘기를 포함하는 디포스폰산 유도체, 그것의 제조방법 및 그것을 포함하는 의약 조성물(novel acyclic amidine-group-containing diphosphonic acid derivatives, process for producing them and medicaments containing these compounds)
KR930019683A (ko) 사이클릭 아미노메틸렌 비스포스포네이트 유도체
KR950704322A (ko) 스피로푸라논 유도체 및 그의 신경변성 질환 치료 용도(Spirofuranone Derivatives and Their Use in the Treatment of Neurodegenerative Disorders)
DE59406844D1 (de) Phosphonobernsteinsäurederivate und ihre verwendung als arzneimittel
DK0412015T3 (da) Hidtil ukendte N-(23-vincristinoyl)- og N-(5-noranhydro-23-vinblastinoyl)-1-aminomethylphosphon- syrederivater, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
HRP930613A2 (en) 4-oxo-azetidine-2-sulphonic acids amides and their salts, process for their production and their use

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee