DE69811905T2 - Cyclohexenon langketten alkohol und diese enthaltendes arzneimittel - Google Patents
Cyclohexenon langketten alkohol und diese enthaltendes arzneimittelInfo
- Publication number
- DE69811905T2 DE69811905T2 DE69811905T DE69811905T DE69811905T2 DE 69811905 T2 DE69811905 T2 DE 69811905T2 DE 69811905 T DE69811905 T DE 69811905T DE 69811905 T DE69811905 T DE 69811905T DE 69811905 T2 DE69811905 T2 DE 69811905T2
- Authority
- DE
- Germany
- Prior art keywords
- chain alcohol
- long chain
- product containing
- medicinal product
- cyclohexenone long
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
- C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
- C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
- C07C45/511—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition involving transformation of singly bound oxygen functional groups to >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
- C07C45/57—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom
- C07C45/59—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with oxygen as the only heteroatom in five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
- C07C45/676—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton by elimination of carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/587—Unsaturated compounds containing a keto groups being part of a ring
- C07C49/703—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups
- C07C49/713—Unsaturated compounds containing a keto groups being part of a ring containing hydroxy groups a keto group being part of a six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP21847497 | 1997-08-13 | ||
PCT/JP1998/003560 WO1999008987A1 (en) | 1997-08-13 | 1998-08-11 | Cyclohexenone long-chain alcohol and medicament containing same |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69811905D1 DE69811905D1 (de) | 2003-04-10 |
DE69811905T2 true DE69811905T2 (de) | 2003-11-06 |
Family
ID=16720502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69811905T Expired - Lifetime DE69811905T2 (de) | 1997-08-13 | 1998-08-11 | Cyclohexenon langketten alkohol und diese enthaltendes arzneimittel |
Country Status (7)
Country | Link |
---|---|
US (1) | US6228893B1 (de) |
EP (1) | EP1003706B1 (de) |
JP (1) | JP3766591B2 (de) |
AT (1) | ATE233724T1 (de) |
CA (1) | CA2299308C (de) |
DE (1) | DE69811905T2 (de) |
WO (1) | WO1999008987A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4469441B2 (ja) | 1999-02-10 | 2010-05-26 | 明治乳業株式会社 | 神経変性疾患の予防又は治療薬 |
JP4490536B2 (ja) * | 2000-01-31 | 2010-06-30 | 明治乳業株式会社 | 脳血管障害に基づく疾患の予防又は治療薬 |
JP2002068973A (ja) * | 2000-06-16 | 2002-03-08 | Meiji Milk Prod Co Ltd | 幹細胞分化誘導促進剤 |
EP1322748B1 (de) * | 2000-10-04 | 2009-12-02 | Meiji Dairies Corporation | Stemzelldifferenzierung induzierende promoter |
JP4250882B2 (ja) * | 2000-10-18 | 2009-04-08 | 住友化学株式会社 | スルホン誘導体およびその製造方法 |
JP4861560B2 (ja) * | 2001-02-19 | 2012-01-25 | 株式会社明治 | 糖尿病合併症治療剤 |
JP3836684B2 (ja) * | 2001-02-19 | 2006-10-25 | 明治乳業株式会社 | 排尿障害治療剤 |
WO2002094252A1 (en) * | 2001-05-24 | 2002-11-28 | Meiji Dairies Corporation | Preventive or remedy for diseases caused by cerebrovascular disturbances |
AU2003235672A1 (en) * | 2002-01-09 | 2003-07-30 | Trident Sciences Llc | Compounds for blocking androgen receptors |
JP4035332B2 (ja) * | 2002-01-22 | 2008-01-23 | 明治乳業株式会社 | シクロヘキセノン長鎖アルコールの製造法 |
EP1533299A4 (de) | 2002-07-19 | 2007-04-04 | Meiji Dairies Corp | Indolderivate und arzneimittel, die diese enthalten |
WO2004087630A1 (en) | 2003-03-28 | 2004-10-14 | Meiji Dairies Corporation | Process for producing cyclohexenone long-chain alcohols |
KR101194137B1 (ko) * | 2004-10-13 | 2012-10-25 | 가부시키가이샤 메이지 | STAT3 인산화 억제 및 Notch1 발현 억제제 |
EP2196200A1 (de) * | 2005-01-18 | 2010-06-16 | Meiji Dairies Corporation | Cyclohexenonderivat zur Prävention oder Behandlung von Hypästhesie oder durch Diabetes verursachter Hyperästhesie |
JP5150807B2 (ja) * | 2005-02-28 | 2013-02-27 | 株式会社明治 | ハイドロキノン長鎖誘導体及び/又はフェノキシ長鎖誘導体及びこれらを含有する医薬 |
US20080312336A1 (en) * | 2005-05-26 | 2008-12-18 | Keisuke Satoh | Preventive and/or Therapeutic Agent for Diabetic Vascular Disorder and Respiratory Disorder |
WO2013147072A1 (ja) * | 2012-03-29 | 2013-10-03 | 大鵬薬品工業株式会社 | 3-(15-ヒドロキシペンタデシル)-2,4,4-トリメチル-2-シクロヘキセン-1-オンの共結晶 |
JP5566521B1 (ja) | 2013-09-27 | 2014-08-06 | 大鵬薬品工業株式会社 | 膀胱・尿道協調不全改善剤 |
US20170035705A1 (en) | 2015-08-04 | 2017-02-09 | Taiho Pharmaceutical Co., Ltd. | Detrusor hyperactivity with impaired contractility ameliorating agent |
KR102387362B1 (ko) | 2016-01-22 | 2022-04-15 | 다이호야쿠힌고교 가부시키가이샤 | 고순도 시클로헥세논 장쇄 알코올의 제조 방법 |
JP2022013721A (ja) | 2020-07-03 | 2022-01-18 | 大鵬薬品工業株式会社 | 排尿症状治療剤 |
BR112023001832A2 (pt) * | 2020-08-07 | 2023-02-23 | Taiho Pharmaceutical Co Ltd | Composto cicloalquenona ou sal do mesmo |
WO2023153422A1 (ja) * | 2022-02-09 | 2023-08-17 | 大鵬薬品工業株式会社 | シクロヘキセノン化合物の結晶形 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04502167A (ja) * | 1989-10-13 | 1992-04-16 | メダフオール | 長鎖脂肪アルコール誘導体、特に細胞栄養分子及び細胞保護分子としてのその使用、並びに、該誘導体を含有する医薬組成物 |
EP0593831B1 (de) * | 1992-11-18 | 1994-05-04 | Medafor | Langkettige Fettalkohole mit neurotropischer und gedächtnissfördernder Wirkung |
-
1998
- 1998-08-11 US US09/463,972 patent/US6228893B1/en not_active Expired - Lifetime
- 1998-08-11 AT AT98936726T patent/ATE233724T1/de not_active IP Right Cessation
- 1998-08-11 EP EP98936726A patent/EP1003706B1/de not_active Expired - Lifetime
- 1998-08-11 CA CA002299308A patent/CA2299308C/en not_active Expired - Lifetime
- 1998-08-11 DE DE69811905T patent/DE69811905T2/de not_active Expired - Lifetime
- 1998-08-11 JP JP2000509675A patent/JP3766591B2/ja not_active Expired - Lifetime
- 1998-08-11 WO PCT/JP1998/003560 patent/WO1999008987A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP1003706A1 (de) | 2000-05-31 |
CA2299308A1 (en) | 1999-02-25 |
JP3766591B2 (ja) | 2006-04-12 |
JP2001515058A (ja) | 2001-09-18 |
US6228893B1 (en) | 2001-05-08 |
EP1003706B1 (de) | 2003-03-05 |
DE69811905D1 (de) | 2003-04-10 |
WO1999008987A1 (en) | 1999-02-25 |
ATE233724T1 (de) | 2003-03-15 |
CA2299308C (en) | 2008-03-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
R082 | Change of representative |
Ref document number: 1003706 Country of ref document: EP Representative=s name: GUENTER WAECHTERSHAEUSER, DE |
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R081 | Change of applicant/patentee |
Ref document number: 1003706 Country of ref document: EP Owner name: UNIVERSITE DE STRASBOURG, FR Free format text: FORMER OWNER: MEIJI CO., LTD., TOKYO, JP Effective date: 20120911 Ref document number: 1003706 Country of ref document: EP Owner name: MEIJI CO., LTD., JP Free format text: FORMER OWNER: MEIJI CO., LTD., TOKYO, JP Effective date: 20120911 Ref document number: 1003706 Country of ref document: EP Owner name: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, FR Free format text: FORMER OWNER: MEIJI CO., LTD., TOKYO, JP Effective date: 20120911 |
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Ref document number: 1003706 Country of ref document: EP Representative=s name: GUENTER WAECHTERSHAEUSER, DE Effective date: 20120911 |