ATE232528T1 - Pyrimidinylpyrazolderivate - Google Patents

Pyrimidinylpyrazolderivate

Info

Publication number
ATE232528T1
ATE232528T1 AT95932229T AT95932229T ATE232528T1 AT E232528 T1 ATE232528 T1 AT E232528T1 AT 95932229 T AT95932229 T AT 95932229T AT 95932229 T AT95932229 T AT 95932229T AT E232528 T1 ATE232528 T1 AT E232528T1
Authority
AT
Austria
Prior art keywords
group
hydrogen atom
chem
formula
pyrimidinylpyrazole
Prior art date
Application number
AT95932229T
Other languages
German (de)
English (en)
Inventor
Akio Ejima
Masamichi Sugimori
Ikuo Mitsui
Original Assignee
Daiichi Seiyaku Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co filed Critical Daiichi Seiyaku Co
Application granted granted Critical
Publication of ATE232528T1 publication Critical patent/ATE232528T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT95932229T 1994-09-26 1995-09-25 Pyrimidinylpyrazolderivate ATE232528T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP22942294 1994-09-26
JP13501095 1995-06-01
PCT/JP1995/001934 WO1996010024A1 (fr) 1994-09-26 1995-09-25 Derive pyrimidinylpyrazole

Publications (1)

Publication Number Publication Date
ATE232528T1 true ATE232528T1 (de) 2003-02-15

Family

ID=26468965

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95932229T ATE232528T1 (de) 1994-09-26 1995-09-25 Pyrimidinylpyrazolderivate

Country Status (13)

Country Link
US (1) US5852019A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0784055B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR100388568B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CN (1) CN1071754C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE232528T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA2201110A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (2) DE69529619T4 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK0784055T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (1) ES2192584T3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI971227L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO313196B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
TW (1) TW312694B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1996010024A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6169086B1 (en) 1997-01-27 2001-01-02 Daiichi Pharmaceutical Co., Ltd. Pyrazole derivatives
TW486478B (en) * 1997-01-27 2002-05-11 Daiichi Seiyaku Co Pyrazole derivatives exhibiting anti-tumor effects and a pharmaceutical composition comprising the same
WO2000005230A1 (fr) * 1998-07-24 2000-02-03 Daiichi Pharmaceutical Co., Ltd. Derives de pyrazole et sels correspondants
WO2000043385A1 (fr) * 1999-01-25 2000-07-27 Zenyaku Kogyo Kabushiki Kaisha Composes heterocycliques et agents antitumoraux les comprenant en tant que principe actif
PT1389617E (pt) * 2001-04-27 2007-04-30 Zenyaku Kogyo Kk Composto heterocíclico e agente antitumoral contendo o mesmo como igrediente activo
WO2003011837A1 (en) * 2001-08-01 2003-02-13 Merck & Co., Inc. Tyrosine kinase inhibitors
FR2850379B1 (fr) * 2003-01-28 2006-11-17 Aventis Pharma Sa Produits n-aryl-heteroaromatiques, compositions les contenant et utilisation
CA2512243A1 (fr) * 2003-01-28 2004-09-16 Aventis Pharma S.A. Produits n-aryl-heteroaromatiques, compositions les contenant et utilisation
US20050130989A1 (en) * 2003-01-28 2005-06-16 Aventis Pharma S. A. N-arylheteroaromatic products compositions containing them and use thereof
US7223759B2 (en) * 2003-09-15 2007-05-29 Anadys Pharmaceuticals, Inc. Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds
JP4733021B2 (ja) * 2004-03-31 2011-07-27 全薬工業株式会社 複素環式化合物及びそれを有効成分とする抗悪性腫瘍剤
RU2443441C2 (ru) * 2005-03-11 2012-02-27 Зеняку Когио Кабусикикайся Иммунодепрессант и противоопухолевое средство, содержащее гетероциклическое соединение в качестве активного ингредиента
US20070244110A1 (en) * 2006-04-14 2007-10-18 Zenyaku Kogyo Kabushiki Kaisha Treatment of prostate cancer, melanoma or hepatic cancer
ES2430821T3 (es) 2006-10-10 2013-11-21 Amgen Inc. Compuestos de N-arilpirazol para usar contra la diabetes
US10287269B2 (en) * 2015-03-26 2019-05-14 Merck Sharp & Dohme Corp. Pyrazolyl pyrimidinone compounds as PDE2 inhibitors
EP3356345B1 (en) 2015-09-30 2023-11-08 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Heteroaryl derivatives as sepiapterin reductase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3778433A (en) * 1969-04-18 1973-12-11 Sumitomo Chemical Co Process for producing benzodiazepine derivatives
JPS4842072A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1971-09-29 1973-06-19
JPS61129129A (ja) * 1984-11-28 1986-06-17 Kureha Chem Ind Co Ltd 抗腫瘍剤
US5102893A (en) * 1986-07-07 1992-04-07 Warner-Lambert Company Trans-6-(2-(n-heteroaryl-3,5-disubstituted)pyrazol-4-yl)-ethyl- or ethenyl)tetrahydro-4-hydroxypyran-2-one inhibitors of cholesterol biosynthesis

Also Published As

Publication number Publication date
NO313196B1 (no) 2002-08-26
FI971227A7 (fi) 1997-05-23
NO971384D0 (no) 1997-03-24
KR970706275A (ko) 1997-11-03
DE69529619D1 (en) 2003-03-20
NO971384L (no) 1997-05-23
CN1166833A (zh) 1997-12-03
KR100388568B1 (ko) 2003-10-04
CA2201110A1 (en) 1996-04-04
DK0784055T3 (da) 2003-06-02
EP0784055B1 (en) 2003-02-12
HK1001396A1 (en) 1998-06-19
CN1071754C (zh) 2001-09-26
DE69529619T2 (de) 2003-12-18
FI971227L (fi) 1997-05-23
US5852019A (en) 1998-12-22
FI971227A0 (fi) 1997-03-24
TW312694B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1997-08-11
WO1996010024A1 (fr) 1996-04-04
ES2192584T3 (es) 2003-10-16
EP0784055A1 (en) 1997-07-16
EP0784055A4 (en) 1998-01-07
DE69529619T4 (de) 2005-01-27

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