ATE23044T1 - Sorbinil durch optische aufspaltung von vorlaeufer-6-fluoro-4-ureidochromansaeure. - Google Patents

Sorbinil durch optische aufspaltung von vorlaeufer-6-fluoro-4-ureidochromansaeure.

Info

Publication number
ATE23044T1
ATE23044T1 AT83306691T AT83306691T ATE23044T1 AT E23044 T1 ATE23044 T1 AT E23044T1 AT 83306691 T AT83306691 T AT 83306691T AT 83306691 T AT83306691 T AT 83306691T AT E23044 T1 ATE23044 T1 AT E23044T1
Authority
AT
Austria
Prior art keywords
fluoro
ureidochroman
sorbinil
precurrent
acid
Prior art date
Application number
AT83306691T
Other languages
English (en)
Inventor
Berkeley W Cue
Bernard S Moore
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE23044T1 publication Critical patent/ATE23044T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Engine Equipment That Uses Special Cycles (AREA)
  • Control Of Turbines (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
  • Saccharide Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT83306691T 1982-11-10 1983-11-03 Sorbinil durch optische aufspaltung von vorlaeufer-6-fluoro-4-ureidochromansaeure. ATE23044T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/440,641 US4435578A (en) 1982-11-10 1982-11-10 Sorbinil by optical resolution of precursor 6-fluoro-4-ureidochroman-4-carboxylic acid
EP83306691A EP0109232B1 (de) 1982-11-10 1983-11-03 Sorbinil durch optische Aufspaltung von Vorläufer-6-Fluoro-4-ureidochromansäure

Publications (1)

Publication Number Publication Date
ATE23044T1 true ATE23044T1 (de) 1986-11-15

Family

ID=23749580

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83306691T ATE23044T1 (de) 1982-11-10 1983-11-03 Sorbinil durch optische aufspaltung von vorlaeufer-6-fluoro-4-ureidochromansaeure.

Country Status (14)

Country Link
US (1) US4435578A (de)
EP (1) EP0109232B1 (de)
JP (4) JPS59101491A (de)
AT (1) ATE23044T1 (de)
BG (1) BG45388A3 (de)
CA (1) CA1202034A (de)
DE (1) DE3367099D1 (de)
GT (1) GT198303963A (de)
HU (1) HU191708B (de)
IE (1) IE56256B1 (de)
PH (1) PH18843A (de)
PL (1) PL143960B1 (de)
SU (1) SU1282816A3 (de)
ZA (1) ZA838336B (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0172719B1 (de) * 1984-08-20 1988-09-21 Pfizer Inc. Verfahren zur Herstellung asymmetrischer Hydantoine
US4620019A (en) * 1984-08-23 1986-10-28 Pfizer Inc. S-6-fluoro-4-aminochroman-4-carboxylic acid derivatives useful as intermediates for sorbinil
US4551542A (en) * 1984-09-26 1985-11-05 Pfizer Inc. Regeneration of 6-fluoro-4-chromanone from 6-fluoro-4-ureidochroman-4-carboxylic acid
WO1986007353A1 (en) 1985-06-14 1986-12-18 Pfizer Inc. Intermediate in the production of an asymmetric hydantoin
US4841079A (en) * 1987-08-07 1989-06-20 Pfizer, Inc. Process for the production of asymmetric hydantoins
US5206367A (en) * 1992-02-18 1993-04-27 Pfizer Inc. Preparation of optically active spiro-hydantoins

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4286098A (en) * 1980-03-28 1981-08-25 Pfizer Inc. Process for the preparation of chiral hydantoins

Also Published As

Publication number Publication date
PL143960B1 (en) 1988-03-31
PL250369A1 (en) 1985-09-24
US4435578A (en) 1984-03-06
JPH032866B2 (de) 1991-01-17
DE3367099D1 (en) 1986-11-27
IE832619L (en) 1984-05-10
EP0109232B1 (de) 1986-10-22
JPH0248555B2 (de) 1990-10-25
GT198303963A (es) 1985-04-30
JPH0244832B2 (de) 1990-10-05
CA1202034A (en) 1986-03-18
BG45388A3 (bg) 1989-05-15
JPS59101491A (ja) 1984-06-12
HUT36124A (en) 1985-08-28
PH18843A (en) 1985-10-10
JPS63211282A (ja) 1988-09-02
IE56256B1 (en) 1991-06-05
HU191708B (en) 1987-03-30
ZA838336B (en) 1985-06-26
SU1282816A3 (ru) 1987-01-07
JPS63211281A (ja) 1988-09-02
EP0109232A1 (de) 1984-05-23
JPS63211278A (ja) 1988-09-02
JPS6344755B2 (de) 1988-09-06

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee