ATE228506T1 - Synthese von acridinderivaten als inhibitoren von multipler medikamentenresistenz - Google Patents
Synthese von acridinderivaten als inhibitoren von multipler medikamentenresistenzInfo
- Publication number
- ATE228506T1 ATE228506T1 AT98934892T AT98934892T ATE228506T1 AT E228506 T1 ATE228506 T1 AT E228506T1 AT 98934892 T AT98934892 T AT 98934892T AT 98934892 T AT98934892 T AT 98934892T AT E228506 T1 ATE228506 T1 AT E228506T1
- Authority
- AT
- Austria
- Prior art keywords
- synthesis
- inhibitors
- drug resistance
- multiple drug
- acridine derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
- C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- C07D219/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Pyridine Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9710612.4A GB9710612D0 (en) | 1997-05-23 | 1997-05-23 | Synthesis of acridine derivatives |
| PCT/EP1998/002991 WO1998052923A1 (en) | 1997-05-23 | 1998-05-22 | Synthesis of acridine derivative multidrug-resistant inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE228506T1 true ATE228506T1 (de) | 2002-12-15 |
Family
ID=10812906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98934892T ATE228506T1 (de) | 1997-05-23 | 1998-05-22 | Synthese von acridinderivaten als inhibitoren von multipler medikamentenresistenz |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6248891B1 (de) |
| EP (1) | EP0983246B1 (de) |
| JP (1) | JP4390861B2 (de) |
| KR (1) | KR100536155B1 (de) |
| CN (1) | CN1178918C (de) |
| AT (1) | ATE228506T1 (de) |
| AU (1) | AU744402B2 (de) |
| BR (1) | BR9809143A (de) |
| CA (1) | CA2289492C (de) |
| DE (1) | DE69809733T2 (de) |
| DK (1) | DK0983246T3 (de) |
| ES (1) | ES2187984T3 (de) |
| GB (1) | GB9710612D0 (de) |
| HK (1) | HK1023995A1 (de) |
| HU (1) | HUP0002083A3 (de) |
| IL (1) | IL132593A (de) |
| PL (1) | PL190109B1 (de) |
| PT (1) | PT983246E (de) |
| WO (1) | WO1998052923A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9708805D0 (en) | 1997-05-01 | 1997-06-25 | Smithkline Beecham Plc | Compounds |
| GB9810876D0 (en) | 1998-05-20 | 1998-07-22 | Smithkline Beecham Plc | Compounds |
| MA26696A1 (fr) | 1998-10-08 | 2004-12-20 | Smithkline Beecham Plc | Derives de tetrahydrobenzazepine nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant |
| DK1189637T3 (da) * | 1999-05-17 | 2006-12-11 | Cancer Res Ventures Ltd | Produkter til forbedring af biotilgængeligheden for oralt indgivne medikamenter |
| SI21507A (sl) | 2003-05-16 | 2004-12-31 | LEK farmacevtska dru�ba d.d. | Postopek za pripravo spojin z ace inhibitornim delovanjem |
| US7829578B1 (en) | 2005-12-12 | 2010-11-09 | Oregon Health & Science University | Aromatic ketones and uses thereof |
| WO2008064011A1 (en) | 2006-11-13 | 2008-05-29 | The Government Of The U.S. Of America As Represented By The Department Of Veterans Affairs | Acridone compounds |
| US8598354B2 (en) | 2008-12-05 | 2013-12-03 | University Of South Florida | Compounds having antiparasitic or anti-infectious activity |
| IL277335B2 (en) * | 2018-03-21 | 2024-03-01 | Izumi Tech Llc | Analogues of alcridar with deuterium |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2783680B2 (ja) * | 1991-01-11 | 1998-08-06 | ラボラトワール、グラクソ、ソシエテ、アノニム | アクリジン誘導体 |
| CZ104197A3 (en) * | 1994-10-05 | 1997-09-17 | Glaxo Wellcome Inc | Pharmaceutical preparation |
-
1997
- 1997-05-23 GB GBGB9710612.4A patent/GB9710612D0/en active Pending
-
1998
- 1998-05-22 PL PL98336937A patent/PL190109B1/pl not_active IP Right Cessation
- 1998-05-22 CA CA002289492A patent/CA2289492C/en not_active Expired - Fee Related
- 1998-05-22 KR KR10-1999-7010781A patent/KR100536155B1/ko not_active IP Right Cessation
- 1998-05-22 DE DE69809733T patent/DE69809733T2/de not_active Expired - Lifetime
- 1998-05-22 CN CNB988051265A patent/CN1178918C/zh not_active Expired - Fee Related
- 1998-05-22 WO PCT/EP1998/002991 patent/WO1998052923A1/en active IP Right Grant
- 1998-05-22 AT AT98934892T patent/ATE228506T1/de not_active IP Right Cessation
- 1998-05-22 IL IL13259398A patent/IL132593A/en not_active IP Right Cessation
- 1998-05-22 ES ES98934892T patent/ES2187984T3/es not_active Expired - Lifetime
- 1998-05-22 US US09/403,158 patent/US6248891B1/en not_active Expired - Fee Related
- 1998-05-22 EP EP98934892A patent/EP0983246B1/de not_active Expired - Lifetime
- 1998-05-22 BR BR9809143-3A patent/BR9809143A/pt not_active Application Discontinuation
- 1998-05-22 HU HU0002083A patent/HUP0002083A3/hu unknown
- 1998-05-22 JP JP54995998A patent/JP4390861B2/ja not_active Expired - Fee Related
- 1998-05-22 AU AU84344/98A patent/AU744402B2/en not_active Ceased
- 1998-05-22 PT PT98934892T patent/PT983246E/pt unknown
- 1998-05-22 DK DK98934892T patent/DK0983246T3/da active
-
2000
- 2000-05-25 HK HK00103130A patent/HK1023995A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0983246A1 (de) | 2000-03-08 |
| KR100536155B1 (ko) | 2005-12-14 |
| CA2289492C (en) | 2009-03-24 |
| JP2002502371A (ja) | 2002-01-22 |
| JP4390861B2 (ja) | 2009-12-24 |
| BR9809143A (pt) | 2000-08-01 |
| US6248891B1 (en) | 2001-06-19 |
| PT983246E (pt) | 2003-04-30 |
| AU744402B2 (en) | 2002-02-21 |
| KR20010012817A (ko) | 2001-02-26 |
| DE69809733D1 (de) | 2003-01-09 |
| HUP0002083A3 (en) | 2002-03-28 |
| ES2187984T3 (es) | 2003-06-16 |
| HK1023995A1 (en) | 2000-09-29 |
| IL132593A (en) | 2004-07-25 |
| CN1255918A (zh) | 2000-06-07 |
| PL190109B1 (pl) | 2005-10-31 |
| IL132593A0 (en) | 2001-03-19 |
| HUP0002083A2 (hu) | 2001-04-28 |
| CN1178918C (zh) | 2004-12-08 |
| CA2289492A1 (en) | 1998-11-26 |
| GB9710612D0 (en) | 1997-07-16 |
| DE69809733T2 (de) | 2003-09-18 |
| EP0983246B1 (de) | 2002-11-27 |
| PL336937A1 (en) | 2000-07-17 |
| WO1998052923A1 (en) | 1998-11-26 |
| DK0983246T3 (da) | 2003-03-24 |
| AU8434498A (en) | 1998-12-11 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE245351T1 (de) | Eletrolytische synthese von peressigsäure | |
| NO20025719D0 (no) | Nye triazolpyrimidinforbindelser | |
| NO971684L (no) | Nye benzoxazoler | |
| ECSP034460A (es) | Nuevos compuestos heterociclicos, su preparacion y su utilizacion como medicamentos, en especial como antibacterianos | |
| DE69912581D1 (de) | Biarylessigsäure-derivate und ihre verwendung als cox-2 inhibitoren | |
| MXPA03011681A (es) | Uso de inhibidores de epoxido hidrolasa soluble, para tratar enfermedades relacionadas con la enfermedad cardiovascular. | |
| DE69840519D1 (de) | Heteroaryl-hexansäureamid-derivate, ihre herstellung und ihre verwendung als selektive inhibitoren der bindung von mip-1-alpha an seinen ccr1 rezeptor | |
| ATE311363T1 (de) | Sulfohydroxamsäure and sulfohydroxamate und ihre verwendung als mek-inhibitoren | |
| BR0308967A (pt) | Derivados de quinolina e isoquinolina, um processo para a sua preparação e sua aplicação como inibidores de inflamação | |
| DE69705829D1 (de) | Meta-substituierte phenylsulphonamidderivate | |
| HK1047098A1 (en) | Tri-aryl acid derivatives as ppar receptor ligands. | |
| IL148932A0 (en) | INHIBITORS OF αLβ2 MEDIATED CELL ADHESION | |
| ATE228506T1 (de) | Synthese von acridinderivaten als inhibitoren von multipler medikamentenresistenz | |
| BR0015836A (pt) | Cristal de 4-carboxiamino-2-etil-1,2,3,4-tetra-hidroquinolina como inibidor de cetp | |
| ATE255584T1 (de) | Pyrimidinverbindungen und ihre verwendung als modulatoren der chemokin-rezeptor-aktivität | |
| DE69702182D1 (de) | Alkylierte styrole als prodrugs zu cox-2-inhibitoren | |
| ATE250584T1 (de) | Synthese von 5- oder 8-bromoisoquinolin derivaten | |
| ATE198323T1 (de) | Diphenylstibene als prodrugs zu cox-2-inhibitoren | |
| DK1165491T3 (da) | LTA4-hydrolase-inhibitorer | |
| TR200400907T4 (tr) | Beta D 5-Tiyoksiloz türevleri, bunları hazırlama yöntemi ve bunların terapötik kullanımları | |
| ATE213236T1 (de) | Substituierte benzyloxyimino-verbindungen | |
| WO2001083423A3 (en) | 2,6-diamino-6-methyl-heptanoic acid and derivatives, process for the preparation thereof and use thereof | |
| RS50861B (sr) | 1,3-dioksolani kao sredstva protiv kašlja | |
| TR200001365T2 (tr) | Yeni heterosiklik ikame edilmiş a-hidroksikarbonik asit türevleri | |
| DE69909097D1 (de) | 5-bicycloindolverbindungen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0983246 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |