DK1189637T3 - Produkter til forbedring af biotilgængeligheden for oralt indgivne medikamenter - Google Patents

Produkter til forbedring af biotilgængeligheden for oralt indgivne medikamenter

Info

Publication number
DK1189637T3
DK1189637T3 DK00931720T DK00931720T DK1189637T3 DK 1189637 T3 DK1189637 T3 DK 1189637T3 DK 00931720 T DK00931720 T DK 00931720T DK 00931720 T DK00931720 T DK 00931720T DK 1189637 T3 DK1189637 T3 DK 1189637T3
Authority
DK
Denmark
Prior art keywords
orally administered
bioavailability
products
improve
administered drugs
Prior art date
Application number
DK00931720T
Other languages
English (en)
Inventor
Johannes Henricus Ma Schellens
Alfred Hermanus Schinkel
Original Assignee
Cancer Res Ventures Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Res Ventures Ltd filed Critical Cancer Res Ventures Ltd
Application granted granted Critical
Publication of DK1189637T3 publication Critical patent/DK1189637T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK00931720T 1999-05-17 2000-05-17 Produkter til forbedring af biotilgængeligheden for oralt indgivne medikamenter DK1189637T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1012066 1999-05-17
NL1012481 1999-06-30

Publications (1)

Publication Number Publication Date
DK1189637T3 true DK1189637T3 (da) 2006-12-11

Family

ID=26642978

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00931720T DK1189637T3 (da) 1999-05-17 2000-05-17 Produkter til forbedring af biotilgængeligheden for oralt indgivne medikamenter

Country Status (10)

Country Link
US (2) US7030132B2 (da)
EP (2) EP1189637B1 (da)
AT (2) ATE337016T1 (da)
AU (1) AU4955200A (da)
CY (1) CY1105795T1 (da)
DE (2) DE60030283T2 (da)
DK (1) DK1189637T3 (da)
ES (1) ES2270834T3 (da)
PT (1) PT1189637E (da)
WO (1) WO2000069390A2 (da)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9718903D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents
ES2270834T3 (es) * 1999-05-17 2007-04-16 Cancer Research Ventures Limited Composiciones para mejorar la biodisponibilidad de farmacos administrados oralmente.
HU0100947D0 (en) * 2001-03-02 2001-05-28 Solvo Kft Screening system based on expression of abcg2 half transporter protein in an expression system free of other abc-transporters, abcg2 homodimers
US7169763B2 (en) * 2002-02-22 2007-01-30 Oliver Yoa-Pu Hu Cytochrome P450 3A inhibitors and enhancers
MXPA06015148A (es) * 2004-07-01 2007-08-21 Netherlands Cancer Inst Combinacion que comprende un inhibidor de bcrp y 4-(4-metilpiperazin-1-ilmetil)-n-[4-metil-3-(4-piridin-3-il) pirimidin-2-ilamino)fenil]-benzamida.
JP2008510558A (ja) 2004-08-27 2008-04-10 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 少なくとも１つの薬剤を投与する、電子制御され、遠隔制御されるピル及びシステム
JP2008521794A (ja) * 2004-11-29 2008-06-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 少なくとも一の薬剤を輸送するための、少なくとも一のセンサを有する電子制御式の錠剤およびシステム
WO2006065125A1 (en) * 2004-12-16 2006-06-22 Het Nederlands Kanter Instituut Means and methods for determining and/or influencing transportation
WO2009083042A1 (en) * 2007-12-31 2009-07-09 Olaf Van Tellingen Methods and means for the treatment of cancer
JP6230772B2 (ja) * 2008-02-18 2017-11-15 シュトコ・ツェーン・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 患者に対する薬物の投与
US8990018B2 (en) * 2008-03-31 2015-03-24 MEDIMETRICS Personalized Drug Delivery B.V. Method of preparing a swallowable capsule comprising a sensor
US9005577B2 (en) 2008-04-30 2015-04-14 Siemens Medical Solutions Usa, Inc. Substrate based PET imaging agents
CN102065930B (zh) * 2008-06-19 2013-05-22 皇家飞利浦电子股份有限公司 用于在潮湿环境下传递粉末状药物的装置
CN102076375B (zh) * 2008-06-25 2013-11-20 皇家飞利浦电子股份有限公司 包括多个药物储存器的电子药丸
JP5497176B2 (ja) 2009-08-12 2014-05-21 コーニンクレッカ フィリップス エヌ ヴェ 圧縮可能な薬品貯槽を備える薬品送出装置
CN106432490B (zh) 2016-09-14 2020-01-07 北京大学 一种abcg2单克隆抗体及其用途

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201084A (en) 1982-06-25 1985-10-11 New Zealand Dev Finance 4-carboxamidoacridine derivatives and pharmaceutical compositions containing such
EP0494623A1 (en) * 1991-01-11 1992-07-15 Laboratoires Glaxo Sa Acridine derivatives
ATE152443T1 (de) 1992-07-10 1997-05-15 Glaxo Lab Sa Anilide-derivate
US5567592A (en) 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
US5786344A (en) * 1994-07-05 1998-07-28 Arch Development Corporation Camptothecin drug combinations and methods with reduced side effects
CZ104197A3 (en) 1994-10-05 1997-09-17 Glaxo Wellcome Inc Pharmaceutical preparation
US5726181A (en) * 1995-06-05 1998-03-10 Bionumerik Pharmaceuticals, Inc. Formulations and compositions of poorly water soluble camptothecin derivatives
US6245805B1 (en) 1995-10-26 2001-06-12 Baker Norton Pharmaceuticals, Inc. Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
GB9710612D0 (en) * 1997-05-23 1997-07-16 Glaxo Group Ltd Synthesis of acridine derivatives
HUP0003546A3 (en) 1997-05-27 2002-12-28 Baker Norton Pharma Compositions for administering taxanes orally to human patients
GB9718903D0 (en) * 1997-09-05 1997-11-12 Glaxo Group Ltd Method,compositions and kits for increasing the oral bioavailability of pharmaceutical agents
IL137466A0 (en) 1998-02-05 2001-07-24 Univ Maryland Breast cancer resistance protein (bcrp) and the dna which encodes it
WO1999065493A1 (en) 1998-06-18 1999-12-23 The George Washington University Methods of administering camptothecin compounds for the treatment of cancer with reduced side effects
ID27253A (id) 1998-08-05 2001-03-22 Aventis Pharma Sa Penggunaan turunan-turunan kampotesin dengan toksisitas gastrointestinal yang tereduksi
ES2270834T3 (es) * 1999-05-17 2007-04-16 Cancer Research Ventures Limited Composiciones para mejorar la biodisponibilidad de farmacos administrados oralmente.
US6521635B1 (en) * 2000-01-20 2003-02-18 The United States Of America As Represented By The Department Of Health And Human Services Inhibition of MXR transport by acridine derivatives

Also Published As

Publication number Publication date
EP1749540A3 (en) 2007-05-30
AU4955200A (en) 2000-12-05
DE60030283D1 (de) 2006-10-05
US20020128282A1 (en) 2002-09-12
EP1749540B1 (en) 2010-10-13
ES2270834T3 (es) 2007-04-16
EP1189637A2 (en) 2002-03-27
DE60045114D1 (de) 2010-11-25
EP1189637B1 (en) 2006-08-23
US7030132B2 (en) 2006-04-18
US20060128743A1 (en) 2006-06-15
ATE484295T1 (de) 2010-10-15
WO2000069390A2 (en) 2000-11-23
WO2000069390A3 (en) 2001-12-13
DE60030283T2 (de) 2007-09-20
PT1189637E (pt) 2007-01-31
ATE337016T1 (de) 2006-09-15
EP1749540A2 (en) 2007-02-07
CY1105795T1 (el) 2011-02-02

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