ATE227572T1 - Lebenschützende mittel, verfahren zu deren verwendung sowie extraktionsverfahren für curcuminoide - Google Patents
Lebenschützende mittel, verfahren zu deren verwendung sowie extraktionsverfahren für curcuminoideInfo
- Publication number
- ATE227572T1 ATE227572T1 AT96923703T AT96923703T ATE227572T1 AT E227572 T1 ATE227572 T1 AT E227572T1 AT 96923703 T AT96923703 T AT 96923703T AT 96923703 T AT96923703 T AT 96923703T AT E227572 T1 ATE227572 T1 AT E227572T1
- Authority
- AT
- Austria
- Prior art keywords
- cucuminoids
- life
- protecting agents
- curcumin
- extraction method
- Prior art date
Links
- 238000000605 extraction Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000003223 protective agent Substances 0.000 title 1
- 239000003963 antioxidant agent Substances 0.000 abstract 2
- 230000003078 antioxidant effect Effects 0.000 abstract 2
- 235000006708 antioxidants Nutrition 0.000 abstract 2
- VFLDPWHFBUODDF-FCXRPNKRSA-N curcumin Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-FCXRPNKRSA-N 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- UEPVWRDHSPMIAZ-IZTHOABVSA-N (1e,4z,6e)-5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)hepta-1,4,6-trien-3-one Chemical compound C1=C(O)C(OC)=CC(\C=C\C(\O)=C\C(=O)\C=C\C=2C=CC(O)=CC=2)=C1 UEPVWRDHSPMIAZ-IZTHOABVSA-N 0.000 abstract 1
- HJTVQHVGMGKONQ-LUZURFALSA-N Curcumin II Natural products C1=C(O)C(OC)=CC(\C=C\C(=O)CC(=O)\C=C\C=2C=CC(O)=CC=2)=C1 HJTVQHVGMGKONQ-LUZURFALSA-N 0.000 abstract 1
- YVGGHNCTFXOJCH-UHFFFAOYSA-N DDT Chemical compound C1=CC(Cl)=CC=C1C(C(Cl)(Cl)Cl)C1=CC=C(Cl)C=C1 YVGGHNCTFXOJCH-UHFFFAOYSA-N 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000001093 anti-cancer Effects 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000002141 anti-parasite Effects 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000002592 antimutagenic agent Substances 0.000 abstract 1
- 239000003096 antiparasitic agent Substances 0.000 abstract 1
- JYTVKRNTTALBBZ-UHFFFAOYSA-N bis demethoxycurcumin Natural products C1=CC(O)=CC=C1C=CC(=O)CC(=O)C=CC1=CC=CC(O)=C1 JYTVKRNTTALBBZ-UHFFFAOYSA-N 0.000 abstract 1
- PREBVFJICNPEKM-YDWXAUTNSA-N bisdemethoxycurcumin Chemical compound C1=CC(O)=CC=C1\C=C\C(=O)CC(=O)\C=C\C1=CC=C(O)C=C1 PREBVFJICNPEKM-YDWXAUTNSA-N 0.000 abstract 1
- 229940109262 curcumin Drugs 0.000 abstract 1
- 235000012754 curcumin Nutrition 0.000 abstract 1
- 239000004148 curcumin Substances 0.000 abstract 1
- NMRUIRRIQNAQEB-UHFFFAOYSA-N demethoxycurcumin Natural products OC(=CC(C=CC1=CC(=C(C=C1)O)OC)=O)C=CC1=CC=C(C=C1)O NMRUIRRIQNAQEB-UHFFFAOYSA-N 0.000 abstract 1
- YXAKCQIIROBKOP-UHFFFAOYSA-N di-p-hydroxycinnamoylmethane Natural products C=1C=C(O)C=CC=1C=CC(=O)C=C(O)C=CC1=CC=C(O)C=C1 YXAKCQIIROBKOP-UHFFFAOYSA-N 0.000 abstract 1
- VFLDPWHFBUODDF-UHFFFAOYSA-N diferuloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(=O)CC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 VFLDPWHFBUODDF-UHFFFAOYSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000007246 mechanism Effects 0.000 abstract 1
- UEPVWRDHSPMIAZ-UHFFFAOYSA-N p-hydroxycinnamoyl feruloylmethane Natural products C1=C(O)C(OC)=CC(C=CC(O)=CC(=O)C=CC=2C=CC(O)=CC=2)=C1 UEPVWRDHSPMIAZ-UHFFFAOYSA-N 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US116195P | 1995-07-14 | 1995-07-14 | |
| PCT/US1996/011431 WO1997003674A1 (en) | 1995-07-14 | 1996-07-12 | Bioprotectant composition, method of use and extraction process of curcuminoids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE227572T1 true ATE227572T1 (de) | 2002-11-15 |
Family
ID=21694687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96923703T ATE227572T1 (de) | 1995-07-14 | 1996-07-12 | Lebenschützende mittel, verfahren zu deren verwendung sowie extraktionsverfahren für curcuminoide |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0839037B1 (de) |
| AT (1) | ATE227572T1 (de) |
| AU (1) | AU6455596A (de) |
| DE (1) | DE69624818T2 (de) |
| WO (1) | WO1997003674A1 (de) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9711962D0 (en) * | 1997-06-10 | 1997-08-06 | Reckitt & Colmann Prod Ltd | Therapeutically active compositions |
| GB9714564D0 (en) * | 1997-07-10 | 1997-09-17 | Zeneca Ltd | Composition |
| DE60033383T2 (de) * | 1999-04-09 | 2007-05-31 | Sabinsa Corp. | Verwendung von tetrahydrocurcuminoiden zur regulation von physiologischen und pathologischen fällen in der haut und mucosa |
| US6653327B2 (en) * | 1999-04-09 | 2003-11-25 | Sabinsa Corporation | Cross-regulin composition of tumeric-derived tetrahydrocurcuminoids for skin lightening and protection against UVB rays |
| WO2001030335A2 (en) * | 1999-10-22 | 2001-05-03 | The Board Of Trustees Of The University Of Illinois | Pharmaceutical compositions useful in the prevention and treatment of beta-amyloid protein-induced disease |
| US7728043B2 (en) | 1999-10-22 | 2010-06-01 | Kim Darrick S H L | Methods for treatment of beta-amyloid protein-induced ocular disease |
| US6887898B1 (en) | 1999-10-22 | 2005-05-03 | Darrick S. H. L. Kim | Pharmaceutical compositions useful in prevention and treatment of beta-Amyloid protein-induced disease |
| US6576273B2 (en) | 2000-08-24 | 2003-06-10 | Chr. Hansen A/S | Purification process for improving total yield of curcuminoid colouring agent |
| KR100742785B1 (ko) * | 2000-08-24 | 2007-07-25 | 시에이치알. 한센 에이/에스 | 쿠르쿠미노이드 색소의 전체 수율을 향상시키기 위한정제방법 |
| US6979470B2 (en) * | 2001-07-17 | 2005-12-27 | Metaproteomics, Llc | Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2 |
| KR20030066927A (ko) * | 2002-02-06 | 2003-08-14 | 구자영 | 쿠르쿠민과 5-프루오로유라실로 이루어진 항암제 및 이항암제의 용도 |
| FR2838644B1 (fr) * | 2002-04-23 | 2005-12-30 | Oreal | Utilisation de derives de la 1,7-bisphenyl heptane-3,5-dione comme actifs inhibant le developpement des odeurs corporelles dans les compositions cosmetiques |
| WO2004031122A1 (de) * | 2002-10-01 | 2004-04-15 | Dr. André Rieks - Labor Für Enzymtechnologie Gmbh | Neue curcumin/tetrahydrocurcumin-derivate für den einsatz in kosmetika, pharmazeutika und bei der ernährung |
| CN101227823B (zh) | 2005-10-13 | 2012-05-23 | 莱拉营养食品有限公司 | 从姜黄提取物中制取四羟基姜黄色素和四氢四羟基姜黄色素浓缩成分的方法 |
| WO2009066303A2 (en) | 2007-11-22 | 2009-05-28 | Ganga Raju Gokaraju | New synergistic phytochemical composition for the treatment of obesity |
| US7785638B2 (en) * | 2008-02-28 | 2010-08-31 | Himalaya Global Holdings, Ltd | Herbal acne control composition, method of manufacturing the same and use thereof |
| WO2018020302A1 (en) * | 2016-07-29 | 2018-02-01 | Synthite Industries Limited | A process for extraction and isolation of curcuminoids |
| WO2018161145A1 (en) | 2017-03-10 | 2018-09-13 | Cavaleri Franco | Curcumin-based compositions & methods of use thereof |
| CZ307916B6 (cs) | 2017-05-08 | 2019-08-21 | mcePharma s. r. o. | Orodispergovatelná tableta s biodostupným kurkuminem a její použití |
| EP3946407A4 (de) * | 2019-03-24 | 2022-12-28 | Patel, Naishadhkumar Ramubhai | Formulierung zur erhöhung der bioverfügbarkeit und stabilität von curcuminoiden und/oder deren derivaten davon |
| MX2023012562A (es) * | 2021-04-30 | 2023-10-30 | Sami Sabinsa Group Ltd | Composiciones para el tratamiento del sindrome de ovario poliquistico. |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2239478A1 (en) * | 1973-07-31 | 1975-02-28 | Dufour Michel | Ethereal fruit oil and oleoresin extn. - from food-plant using water-soluble solvents pref. methylal |
| CH609215A5 (de) * | 1976-03-09 | 1979-02-28 | Nestle Sa | |
| DE2924345A1 (de) * | 1979-06-15 | 1981-01-08 | Nattermann A & Cie | Verfahren zur herstellung eines curcumatrockenextraktes aus rhizoma curcumae longae bzw. rhizoma curcumae xanthorrhizae und gewinnung des aetherischen curcumaoels |
| US4263333A (en) * | 1979-09-12 | 1981-04-21 | General Foods Corporation | Curcumin-metal color complexes |
| US4719111A (en) * | 1985-06-14 | 1988-01-12 | Wilson Lynn M | Novel composition for treatment of decubitus ulcers |
| CA1297718C (en) * | 1985-12-20 | 1992-03-24 | Paul H. Todd, Jr. | Herb flavoring and/or antioxidant composition and process |
| US5108750A (en) * | 1986-09-08 | 1992-04-28 | Yaguang Liu | Pharmaceutical compositions for reducing hyperlipidemia and platelet-aggregation |
| JPH0249747A (ja) * | 1988-08-12 | 1990-02-20 | Kobe Steel Ltd | 抗酸化剤 |
| KR920004818B1 (ko) * | 1989-11-28 | 1992-06-18 | 태평양화학 주식회사 | 세포 보호제 조성물 |
| US5120538A (en) * | 1990-02-05 | 1992-06-09 | Pt Darya-Varia Laboratoria | Combinations of compounds isolated from curcuma spp as anti-inflammatory agents |
| DE4137540A1 (de) * | 1991-11-14 | 1993-05-19 | Steigerwald Arzneimittelwerk | Verwendung von praeparaten der curcuma-pflanzen |
| WO1994013743A1 (en) * | 1992-12-17 | 1994-06-23 | Novo Nordisk A/S | Method for isolation of vegetable oleoresins producible by hexane extraction |
| ES2114982T3 (es) * | 1993-08-17 | 1998-06-16 | Nestle Sa | Procedimiento de extraccion de antioxidante vegetal en forma liquida. |
| US5401504B1 (en) * | 1993-12-28 | 1998-04-21 | Univ Mississippi Medical Cente | Use of tumeric in wound healing |
| PT726074E (pt) * | 1994-08-03 | 2003-10-31 | A C Pharmaceutical Internation | Metodo de obtencao de extractos apolares e polares de curcuma e a sua aplicacao |
-
1996
- 1996-07-12 DE DE69624818T patent/DE69624818T2/de not_active Expired - Lifetime
- 1996-07-12 WO PCT/US1996/011431 patent/WO1997003674A1/en not_active Ceased
- 1996-07-12 AU AU64555/96A patent/AU6455596A/en not_active Abandoned
- 1996-07-12 EP EP96923703A patent/EP0839037B1/de not_active Expired - Lifetime
- 1996-07-12 AT AT96923703T patent/ATE227572T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO1997003674A1 (en) | 1997-02-06 |
| EP0839037A4 (de) | 1999-03-03 |
| EP0839037A1 (de) | 1998-05-06 |
| AU6455596A (en) | 1997-02-18 |
| DE69624818D1 (de) | 2002-12-19 |
| DE69624818T2 (de) | 2003-04-10 |
| EP0839037B1 (de) | 2002-11-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |