ATE226728T1 - Verfahren und testsätze zur erzeugung von licht von einer acridan-verbindung - Google Patents

Verfahren und testsätze zur erzeugung von licht von einer acridan-verbindung

Info

Publication number
ATE226728T1
ATE226728T1 AT95931030T AT95931030T ATE226728T1 AT E226728 T1 ATE226728 T1 AT E226728T1 AT 95931030 T AT95931030 T AT 95931030T AT 95931030 T AT95931030 T AT 95931030T AT E226728 T1 ATE226728 T1 AT E226728T1
Authority
AT
Austria
Prior art keywords
assay
reaction
chemiluminescent
compound
acridan
Prior art date
Application number
AT95931030T
Other languages
English (en)
Inventor
Hashem Akhavan-Tafti
Zahra Arghavani
Renuka Desilva
Original Assignee
Lumigen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lumigen Inc filed Critical Lumigen Inc
Application granted granted Critical
Publication of ATE226728T1 publication Critical patent/ATE226728T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/02Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with only hydrogen, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D219/00Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT95931030T 1994-09-02 1995-08-30 Verfahren und testsätze zur erzeugung von licht von einer acridan-verbindung ATE226728T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30046294A 1994-09-02 1994-09-02
PCT/US1995/011031 WO1996007912A1 (en) 1994-09-02 1995-08-30 Novel method and kits for producing light from an acridan compound

Publications (1)

Publication Number Publication Date
ATE226728T1 true ATE226728T1 (de) 2002-11-15

Family

ID=23159199

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95931030T ATE226728T1 (de) 1994-09-02 1995-08-30 Verfahren und testsätze zur erzeugung von licht von einer acridan-verbindung

Country Status (7)

Country Link
EP (1) EP0778946B1 (de)
JP (1) JPH10508191A (de)
AT (1) ATE226728T1 (de)
AU (1) AU3461995A (de)
CA (1) CA2197669A1 (de)
DE (1) DE69528661T2 (de)
WO (1) WO1996007912A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6017769A (en) * 1998-06-17 2000-01-25 Lumigen, Inc. Non-enzymatic methods of generating chemiluminescence from acridan alkenes
US6162610A (en) * 1998-09-11 2000-12-19 Tropix, Inc. Xanthan-ester and acridan substrates for horseradish peroxidase
US7906293B2 (en) 2007-04-09 2011-03-15 Abbott Laboratories Acridinium phenyl esters useful in the analysis of biological
CN115993457B (zh) * 2023-03-22 2023-06-09 广州科方生物技术股份有限公司 一种用于化学发光免疫分析仪检测光子含量的发光剂及其制配方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4918192A (en) * 1986-10-06 1990-04-17 Ciba Corning Diagnostics Corp. Polysubstituted aryl acridinium esters
US5290936A (en) * 1987-12-31 1994-03-01 London Diagnostics, Inc. Nitro substituted chemiluminescent labels and their conjugates, and assays therefrom
US5491072A (en) * 1993-05-17 1996-02-13 Lumigen, Inc. N-alkylacridan carboxyl derivatives useful for chemiluminescent detection

Also Published As

Publication number Publication date
CA2197669A1 (en) 1996-03-14
DE69528661D1 (de) 2002-11-28
EP0778946B1 (de) 2002-10-23
DE69528661T2 (de) 2003-07-10
WO1996007912A1 (en) 1996-03-14
JPH10508191A (ja) 1998-08-18
EP0778946A4 (de) 1999-01-27
EP0778946A1 (de) 1997-06-18
AU3461995A (en) 1996-03-27

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