ATE218563T1 - Piperidinone als tachykininantagoniste - Google Patents

Piperidinone als tachykininantagoniste

Info

Publication number
ATE218563T1
ATE218563T1 AT97901034T AT97901034T ATE218563T1 AT E218563 T1 ATE218563 T1 AT E218563T1 AT 97901034 T AT97901034 T AT 97901034T AT 97901034 T AT97901034 T AT 97901034T AT E218563 T1 ATE218563 T1 AT E218563T1
Authority
AT
Austria
Prior art keywords
compounds
tachykine
piperidinone
antagonist
preparation
Prior art date
Application number
AT97901034T
Other languages
English (en)
Inventor
Alexander Roderick Mackenzie
Allan Patrick Marchington
Donald Stuart Middleton
Sandra Dora Meadows
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Application granted granted Critical
Publication of ATE218563T1 publication Critical patent/ATE218563T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT97901034T 1996-01-22 1997-01-09 Piperidinone als tachykininantagoniste ATE218563T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9601202.6A GB9601202D0 (en) 1996-01-22 1996-01-22 Piperidones
PCT/EP1997/000162 WO1997027185A1 (en) 1996-01-22 1997-01-09 Piperidone tachykinin antagonists

Publications (1)

Publication Number Publication Date
ATE218563T1 true ATE218563T1 (de) 2002-06-15

Family

ID=10787341

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97901034T ATE218563T1 (de) 1996-01-22 1997-01-09 Piperidinone als tachykininantagoniste

Country Status (16)

Country Link
US (1) US6262075B1 (de)
EP (1) EP0888337B1 (de)
JP (1) JP3140063B2 (de)
AT (1) ATE218563T1 (de)
AU (1) AU1442297A (de)
CA (1) CA2240964C (de)
CO (1) CO4560412A1 (de)
DE (1) DE69713075T2 (de)
DK (1) DK0888337T3 (de)
ES (1) ES2175328T3 (de)
GB (1) GB9601202D0 (de)
HR (1) HRP970040A2 (de)
MA (1) MA26418A1 (de)
PT (1) PT888337E (de)
TN (1) TNSN97014A1 (de)
WO (1) WO1997027185A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9600235D0 (en) * 1996-01-05 1996-03-06 Pfizer Ltd Therapeutic agents
WO1999019297A1 (en) * 1997-10-15 1999-04-22 Coelacanth Chemical Corporation Synthesis of azetidine derivatives
CN1121398C (zh) 1997-12-04 2003-09-17 三共株式会社 脂环式酰化杂环衍生物
GB9812037D0 (en) * 1998-06-04 1998-07-29 Pfizer Ltd Piperidones
GB9924141D0 (en) * 1998-10-30 1999-12-15 Zeneca Ltd Treatment of gastric asthma
GB0005366D0 (en) * 2000-03-06 2000-04-26 Xenova Ltd Pharmaceutical compounds
TW200508221A (en) * 2003-06-13 2005-03-01 Astrazeneca Ab New azetidine compounds
US20040265238A1 (en) 2003-06-27 2004-12-30 Imtiaz Chaudry Inhalable formulations for treating pulmonary hypertension and methods of using same
DE10336274A1 (de) * 2003-08-07 2005-03-10 Honeywell Specialty Chemicals Verfahren zur Herstellung von geminalen Difluoralkanen
WO2006137791A1 (en) * 2005-06-23 2006-12-28 Astrazeneca Ab New azetidine derivatives as neurokinin receptor antagonists for the treatment of gastrointestinal diseases
CA2612133A1 (en) * 2005-06-23 2006-12-28 Astrazeneca Ab New azetidine derivatives as neurokinin receptor antagonists for the treatment of gastrointestinal diseases
AR057828A1 (es) 2005-09-29 2007-12-19 Astrazeneca Ab Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
AR056087A1 (es) * 2005-09-29 2007-09-19 Astrazeneca Ab Derivados de azetidina como antagonistas de receptores de neuroquina nk
US8106208B2 (en) 2006-05-18 2012-01-31 Albireo Ab Benzamide compounds that act as NK receptor antagonists
CN101641099A (zh) 2007-01-24 2010-02-03 葛兰素集团有限公司 包含3,5-二氨基-6-(2,3-二氯苯基)-1,2,4-三嗪或r(-)-2,4-二氨基-5-(2,3-二氯苯基)-6-氟甲基嘧啶和nk1的药物组合物
AR074755A1 (es) * 2008-12-16 2011-02-09 Astrazeneca Ab Derivados cuaternarios de piperidina y sus usos
DK2592934T3 (en) * 2010-07-16 2015-10-26 Nivalis Therapeutics Inc NOVEL dihydropyridin-2 (1H) -one compounds as S-NITROSOGLUTATHIONREDUKTASEINHIBITORER and neurokinin-3 receptor antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
TW432061B (en) * 1994-08-09 2001-05-01 Pfizer Res & Dev Lactams
FR2729951B1 (fr) 1995-01-30 1997-04-18 Sanofi Sa Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant

Also Published As

Publication number Publication date
JPH11505271A (ja) 1999-05-18
MA26418A1 (fr) 2004-12-20
HRP970040A2 (en) 1998-06-30
JP3140063B2 (ja) 2001-03-05
CA2240964C (en) 2002-06-25
TNSN97014A1 (fr) 2005-03-15
GB9601202D0 (en) 1996-03-20
DK0888337T3 (da) 2002-07-01
CO4560412A1 (es) 1998-02-10
PT888337E (pt) 2002-09-30
DE69713075T2 (de) 2003-02-27
EP0888337A1 (de) 1999-01-07
WO1997027185A1 (en) 1997-07-31
AU1442297A (en) 1997-08-20
CA2240964A1 (en) 1997-07-31
DE69713075D1 (de) 2002-07-11
EP0888337B1 (de) 2002-06-05
US6262075B1 (en) 2001-07-17
ES2175328T3 (es) 2002-11-16

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee