CO4560412A1 - Piperidonas - Google Patents

Piperidonas

Info

Publication number
CO4560412A1
CO4560412A1 CO97001936A CO97001936A CO4560412A1 CO 4560412 A1 CO4560412 A1 CO 4560412A1 CO 97001936 A CO97001936 A CO 97001936A CO 97001936 A CO97001936 A CO 97001936A CO 4560412 A1 CO4560412 A1 CO 4560412A1
Authority
CO
Colombia
Prior art keywords
compounds
preparation
cycloalkyl
piperidones
proviso
Prior art date
Application number
CO97001936A
Other languages
English (en)
Inventor
Alexander Roderick Mackenzie
Allan Patrick Marchington
Donald Stuart Middleton
Sandra Dora Meadows
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Publication of CO4560412A1 publication Critical patent/CO4560412A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA COMPUESTOS DE FORMULA,(I) Y SALES DE ADICION DE ACIDOS FARMACEU- TICOS ACEPTABLES EN LA QUE X ES UN ENLACE DIRECTO O ALQUILENO C1-C4, Y R ES CICLOALQUILO C3-C7 OPCIO NALMENTE SUSTITUIDO POR 1 O 2 SUSTITUYENTES SELECC IONADOS CADA UNO INDEPENDIENTEMENTE ENTRE FLURO Y CICLOALQUILO C3-C7 A CONDICION DE QUE X NO ES METI LO CUANDO R ES CICLOPROPILO JUNTO CON PROCEDIMIEN- TOS PARA LA PREPARACION DE INTERMEDIOS USADOS EN LA PREPARACION DE COMPOSICIONES QUE CONTIENEN Y USOS DE TALES COMPUESTOS ESTOS COMPUESTOS SON UTI- LES COMO ANTAGONISTAS DE TAQUIQUININAS. VER FIGURA 1.
CO97001936A 1996-01-22 1997-01-17 Piperidonas CO4560412A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9601202.6A GB9601202D0 (en) 1996-01-22 1996-01-22 Piperidones

Publications (1)

Publication Number Publication Date
CO4560412A1 true CO4560412A1 (es) 1998-02-10

Family

ID=10787341

Family Applications (1)

Application Number Title Priority Date Filing Date
CO97001936A CO4560412A1 (es) 1996-01-22 1997-01-17 Piperidonas

Country Status (16)

Country Link
US (1) US6262075B1 (es)
EP (1) EP0888337B1 (es)
JP (1) JP3140063B2 (es)
AT (1) ATE218563T1 (es)
AU (1) AU1442297A (es)
CA (1) CA2240964C (es)
CO (1) CO4560412A1 (es)
DE (1) DE69713075T2 (es)
DK (1) DK0888337T3 (es)
ES (1) ES2175328T3 (es)
GB (1) GB9601202D0 (es)
HR (1) HRP970040A2 (es)
MA (1) MA26418A1 (es)
PT (1) PT888337E (es)
TN (1) TNSN97014A1 (es)
WO (1) WO1997027185A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9600235D0 (en) * 1996-01-05 1996-03-06 Pfizer Ltd Therapeutic agents
AU1089599A (en) * 1997-10-15 1999-05-03 Coelacanth Chemical Corporation Synthesis of azetidine derivatives
WO1999028307A1 (fr) * 1997-12-04 1999-06-10 Sankyo Company, Limited Derives heterocycliques alicycliques acyles
GB9812037D0 (en) * 1998-06-04 1998-07-29 Pfizer Ltd Piperidones
GB9924141D0 (en) * 1998-10-30 1999-12-15 Zeneca Ltd Treatment of gastric asthma
GB0005366D0 (en) * 2000-03-06 2000-04-26 Xenova Ltd Pharmaceutical compounds
TW200508221A (en) * 2003-06-13 2005-03-01 Astrazeneca Ab New azetidine compounds
US20040265238A1 (en) 2003-06-27 2004-12-30 Imtiaz Chaudry Inhalable formulations for treating pulmonary hypertension and methods of using same
DE10336274A1 (de) * 2003-08-07 2005-03-10 Honeywell Specialty Chemicals Verfahren zur Herstellung von geminalen Difluoralkanen
AU2006259891A1 (en) * 2005-06-23 2006-12-28 Albireo Ab New azetidine derivatives as neurokinin receptor antagonists for the treatment of gastrointestinal diseases
CN101208327A (zh) * 2005-06-23 2008-06-25 阿斯利康(瑞典)有限公司 作为神经激肽受体拮抗剂用于治疗胃肠疾病的新氮杂环丁烷衍生物
AR057828A1 (es) 2005-09-29 2007-12-19 Astrazeneca Ab Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
AR056087A1 (es) * 2005-09-29 2007-09-19 Astrazeneca Ab Derivados de azetidina como antagonistas de receptores de neuroquina nk
US8106208B2 (en) 2006-05-18 2012-01-31 Albireo Ab Benzamide compounds that act as NK receptor antagonists
EA200970706A1 (ru) 2007-01-24 2010-02-26 Глэксо Груп Лимитед Новые фармацевтические композиции
WO2010071575A1 (en) * 2008-12-16 2010-06-24 Astrazeneca Ab Quaternary piperidine derivatives and uses thereof
ES2550939T3 (es) 2010-07-16 2015-11-13 Nivalis Therapeutics, Inc. Nuevos compuestos de dihidropiridin-2-(1H)-ona como inhibidores de la S-nitrosoglutatión reductasa y antagonistas del receptor de la neurocinina-3

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676055B1 (fr) 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
TW432061B (en) * 1994-08-09 2001-05-01 Pfizer Res & Dev Lactams
FR2729951B1 (fr) * 1995-01-30 1997-04-18 Sanofi Sa Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant

Also Published As

Publication number Publication date
TNSN97014A1 (fr) 2005-03-15
EP0888337A1 (en) 1999-01-07
AU1442297A (en) 1997-08-20
CA2240964A1 (en) 1997-07-31
MA26418A1 (fr) 2004-12-20
HRP970040A2 (en) 1998-06-30
DE69713075D1 (de) 2002-07-11
US6262075B1 (en) 2001-07-17
PT888337E (pt) 2002-09-30
ATE218563T1 (de) 2002-06-15
EP0888337B1 (en) 2002-06-05
JP3140063B2 (ja) 2001-03-05
WO1997027185A1 (en) 1997-07-31
DK0888337T3 (da) 2002-07-01
ES2175328T3 (es) 2002-11-16
DE69713075T2 (de) 2003-02-27
GB9601202D0 (en) 1996-03-20
CA2240964C (en) 2002-06-25
JPH11505271A (ja) 1999-05-18

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