DE69713075D1 - Piperidinone als tachykininantagoniste - Google Patents

Piperidinone als tachykininantagoniste

Info

Publication number
DE69713075D1
DE69713075D1 DE69713075T DE69713075T DE69713075D1 DE 69713075 D1 DE69713075 D1 DE 69713075D1 DE 69713075 T DE69713075 T DE 69713075T DE 69713075 T DE69713075 T DE 69713075T DE 69713075 D1 DE69713075 D1 DE 69713075D1
Authority
DE
Germany
Prior art keywords
compounds
tachykinine
antagoniste
piperidinone
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69713075T
Other languages
English (en)
Other versions
DE69713075T2 (de
Inventor
Roderick Mackenzie
Patrick Marchington
Stuart Middleton
Dora Meadows
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Ltd
Pfizer Research and Development Co NV SA
Original Assignee
Pfizer Ltd
Pfizer Research and Development Co NV SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Ltd, Pfizer Research and Development Co NV SA filed Critical Pfizer Ltd
Application granted granted Critical
Publication of DE69713075D1 publication Critical patent/DE69713075D1/de
Publication of DE69713075T2 publication Critical patent/DE69713075T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Obesity (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE69713075T 1996-01-22 1997-01-09 Piperidinone als tachykininantagoniste Expired - Fee Related DE69713075T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9601202.6A GB9601202D0 (en) 1996-01-22 1996-01-22 Piperidones
PCT/EP1997/000162 WO1997027185A1 (en) 1996-01-22 1997-01-09 Piperidone tachykinin antagonists

Publications (2)

Publication Number Publication Date
DE69713075D1 true DE69713075D1 (de) 2002-07-11
DE69713075T2 DE69713075T2 (de) 2003-02-27

Family

ID=10787341

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69713075T Expired - Fee Related DE69713075T2 (de) 1996-01-22 1997-01-09 Piperidinone als tachykininantagoniste

Country Status (16)

Country Link
US (1) US6262075B1 (de)
EP (1) EP0888337B1 (de)
JP (1) JP3140063B2 (de)
AT (1) ATE218563T1 (de)
AU (1) AU1442297A (de)
CA (1) CA2240964C (de)
CO (1) CO4560412A1 (de)
DE (1) DE69713075T2 (de)
DK (1) DK0888337T3 (de)
ES (1) ES2175328T3 (de)
GB (1) GB9601202D0 (de)
HR (1) HRP970040A2 (de)
MA (1) MA26418A1 (de)
PT (1) PT888337E (de)
TN (1) TNSN97014A1 (de)
WO (1) WO1997027185A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9600235D0 (en) * 1996-01-05 1996-03-06 Pfizer Ltd Therapeutic agents
WO1999019297A1 (en) * 1997-10-15 1999-04-22 Coelacanth Chemical Corporation Synthesis of azetidine derivatives
ATE297906T1 (de) * 1997-12-04 2005-07-15 Sankyo Co Alicyclische acylierte heterocyclenderivate
GB9812037D0 (en) * 1998-06-04 1998-07-29 Pfizer Ltd Piperidones
GB9924141D0 (en) * 1998-10-30 1999-12-15 Zeneca Ltd Treatment of gastric asthma
GB0005366D0 (en) * 2000-03-06 2000-04-26 Xenova Ltd Pharmaceutical compounds
TW200508221A (en) * 2003-06-13 2005-03-01 Astrazeneca Ab New azetidine compounds
US20040265238A1 (en) 2003-06-27 2004-12-30 Imtiaz Chaudry Inhalable formulations for treating pulmonary hypertension and methods of using same
DE10336274A1 (de) * 2003-08-07 2005-03-10 Honeywell Specialty Chemicals Verfahren zur Herstellung von geminalen Difluoralkanen
US20100069346A1 (en) * 2005-06-23 2010-03-18 Sara Holmqvist New Azetidine Derivatives as Neurokinin Receptor Antagonists for the Treatment of Gastrointestinal Diseases
EP1899318A4 (de) * 2005-06-23 2010-03-17 Astrazeneca Ab Neue azetidinderivate als neurokininrezeptorantagonisten zur behandlung von magen-darm-erkrankungen
AR057828A1 (es) * 2005-09-29 2007-12-19 Astrazeneca Ab Compuestos derivados de azetidina, su preparacion y composicion farmaceuutica
AR056087A1 (es) * 2005-09-29 2007-09-19 Astrazeneca Ab Derivados de azetidina como antagonistas de receptores de neuroquina nk
US8106208B2 (en) 2006-05-18 2012-01-31 Albireo Ab Benzamide compounds that act as NK receptor antagonists
WO2008090114A1 (en) 2007-01-24 2008-07-31 Glaxo Group Limited Pharmaceutical compositions comprising 2-methoxy-5- (5-trifluoromethyl-tetrazol-i-yl-benzyl) - (2s-phenyl-piperidin-3s-yl-)
WO2010071575A1 (en) * 2008-12-16 2010-06-24 Astrazeneca Ab Quaternary piperidine derivatives and uses thereof
US8946434B2 (en) 2010-07-16 2015-02-03 N30 Pharmaceuticals, Inc. Dihydropyridin-2(1H)-one compound as S-nirtosoglutathione reductase inhibitors and neurokinin-3 receptor antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2676055B1 (fr) * 1991-05-03 1993-09-03 Sanofi Elf Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
TW432061B (en) * 1994-08-09 2001-05-01 Pfizer Res & Dev Lactams
FR2729951B1 (fr) 1995-01-30 1997-04-18 Sanofi Sa Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant

Also Published As

Publication number Publication date
EP0888337A1 (de) 1999-01-07
JP3140063B2 (ja) 2001-03-05
AU1442297A (en) 1997-08-20
CA2240964C (en) 2002-06-25
DK0888337T3 (da) 2002-07-01
DE69713075T2 (de) 2003-02-27
GB9601202D0 (en) 1996-03-20
CO4560412A1 (es) 1998-02-10
ATE218563T1 (de) 2002-06-15
ES2175328T3 (es) 2002-11-16
CA2240964A1 (en) 1997-07-31
EP0888337B1 (de) 2002-06-05
PT888337E (pt) 2002-09-30
JPH11505271A (ja) 1999-05-18
US6262075B1 (en) 2001-07-17
TNSN97014A1 (fr) 2005-03-15
WO1997027185A1 (en) 1997-07-31
HRP970040A2 (en) 1998-06-30
MA26418A1 (fr) 2004-12-20

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8339 Ceased/non-payment of the annual fee