ATE218163T1 - Von pflanzen abgeleitetes enzym und dna-sequenzen und ihre verwendung - Google Patents
Von pflanzen abgeleitetes enzym und dna-sequenzen und ihre verwendungInfo
- Publication number
- ATE218163T1 ATE218163T1 AT92913708T AT92913708T ATE218163T1 AT E218163 T1 ATE218163 T1 AT E218163T1 AT 92913708 T AT92913708 T AT 92913708T AT 92913708 T AT92913708 T AT 92913708T AT E218163 T1 ATE218163 T1 AT E218163T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- gst
- date
- dna sequences
- subunit
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1085—Transferases (2.) transferring alkyl or aryl groups other than methyl groups (2.5)
- C12N9/1088—Glutathione transferase (2.5.1.18)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
- C12N15/8237—Externally regulated expression systems
- C12N15/8238—Externally regulated expression systems chemically inducible, e.g. tetracycline
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
- C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
- C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919114259A GB9114259D0 (en) | 1991-07-02 | 1991-07-02 | Plant derived enzyme and dna sequences |
PCT/GB1992/001187 WO1993001294A1 (en) | 1991-07-02 | 1992-07-01 | Plant-derived enzyme and dna sequences, and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE218163T1 true ATE218163T1 (de) | 2002-06-15 |
Family
ID=10697673
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92913708T ATE218163T1 (de) | 1991-07-02 | 1992-07-01 | Von pflanzen abgeleitetes enzym und dna-sequenzen und ihre verwendung |
Country Status (11)
Country | Link |
---|---|
US (2) | US5589614A (de) |
EP (1) | EP0603190B1 (de) |
JP (2) | JP3377526B2 (de) |
AT (1) | ATE218163T1 (de) |
AU (2) | AU672362B2 (de) |
CA (1) | CA2111983C (de) |
DE (1) | DE69232620T2 (de) |
DK (1) | DK0603190T3 (de) |
ES (1) | ES2178637T3 (de) |
GB (1) | GB9114259D0 (de) |
WO (1) | WO1993001294A1 (de) |
Families Citing this family (86)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9422083D0 (en) * | 1994-11-02 | 1994-12-21 | Innes John Centre | Genetic control of flowering |
DE19501840A1 (de) * | 1995-01-23 | 1996-07-25 | Bayer Ag | Desoxyribonukleinsäure und ihre Verwendung |
GB9515941D0 (en) | 1995-08-03 | 1995-10-04 | Zeneca Ltd | DNA constructs |
US5859338A (en) * | 1995-06-06 | 1999-01-12 | California Institute Of Technology | Plant clavata1 nucleic acids, transformed plants, and proteins |
EP0859850B1 (de) * | 1995-09-22 | 2006-10-18 | Syngenta Limited | Pflanzliche glutathion-s-transferase-promotoren |
DE69737414D1 (de) * | 1996-05-09 | 2007-04-12 | Jujo Paper Co Ltd | Vektor zum gentransfer in pflanzen, der eine wahlweise deletion des markergens erlaubt |
US6063570A (en) | 1997-09-05 | 2000-05-16 | E. I. Du Pont De Nemours And Company | Soybean glutathione-S-transferase enzymes |
US6096504A (en) * | 1997-09-05 | 2000-08-01 | E. I. Du Pont Nemours And Company | Maize glutathione-S-transferase enzymes |
US5962229A (en) * | 1997-09-05 | 1999-10-05 | E.I. Du Pont De Nemours And Company | Maize glutathione-S-transferase enzymes |
US6168954B1 (en) | 1997-09-05 | 2001-01-02 | E. I. Du Pont De Nemours & Company | Soybean glutathione-S-transferase enzymes |
GB9719727D0 (en) | 1997-09-16 | 1997-11-19 | Rhone Poulenc Agriculture | New plant genes |
BR9908126A (pt) | 1998-02-20 | 2000-10-24 | Zeneca Ltd | Produção de semente hìbrida |
GB9820970D0 (en) * | 1998-09-25 | 1998-11-18 | Zeneca Ltd | Promoter |
WO2000018936A1 (en) * | 1998-09-30 | 2000-04-06 | E.I. Du Pont De Nemours And Company | Soybean glutathione-s-transferase enzymes |
AU1063899A (en) * | 1998-09-30 | 2000-04-17 | E.I. Du Pont De Nemours And Company | Maize glutathione-s-transferase enzymes |
AU2924800A (en) * | 1999-03-03 | 2000-09-21 | Syngenta Limited | Use of glutathione-s-transferase to increase stress tolerance in plants |
US6462257B1 (en) | 1999-06-01 | 2002-10-08 | Institute Of Paper Science And Technology, Inc. | Vicilin-like seed storage protein gene promoter and methods of using the same |
GB9922346D0 (en) * | 1999-09-21 | 1999-11-24 | Zeneca Ltd | Improvements in or relating to organic compounds |
JP4582853B2 (ja) * | 2000-02-25 | 2010-11-17 | 岩手県 | グルタチオン−s−トランスフェラーゼ遺伝子を導入した低温抵抗性イネ |
WO2003095655A2 (de) | 2002-05-08 | 2003-11-20 | Basf Plant Science Gmbh | Verfahren zum erhöhen des ölgehaltes in pflanzen |
CA2493364A1 (en) | 2002-07-26 | 2004-02-12 | Basf Plant Science Gmbh | Inversion of the negative-selective effect of negative marker proteins using selection methods |
KR20060013369A (ko) | 2003-03-28 | 2006-02-09 | 독립행정법인농업생물자원연구소 | 재조합 단백질이 다량 생산되는 식물 저장 기관의 생산방법 및 신규 재조합 단백질 |
EP1781784A2 (de) | 2004-08-02 | 2007-05-09 | BASF Plant Science GmbH | Verfahren zur isolierung von transkriptionsterminationssequenzen |
US9085774B2 (en) | 2005-04-19 | 2015-07-21 | Basf Plant Science Gmbh | Methods controlling gene expression |
KR101419056B1 (ko) | 2005-04-29 | 2014-07-11 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 다층 폴리우레탄 보호 필름 |
EP2159289A3 (de) | 2005-06-23 | 2010-03-24 | BASF Plant Science GmbH | Verbessertes Verfahren zur Herstellung stabil transformierter Pflanzen |
EP2980220A1 (de) | 2005-09-20 | 2016-02-03 | BASF Plant Science GmbH | Verbesserte verfahren zur steuerung der genexpression |
AU2007356171B8 (en) | 2006-08-04 | 2014-01-16 | Bp Corporation North America Inc. | Glucanases, nucleic acids encoding them, and methods for making and using them |
PL2617823T3 (pl) | 2006-09-21 | 2015-12-31 | Basf Enzymes Llc | Fitazy, kodujące je kwasy nukleinowe oraz sposoby ich wytwarzania i stosowania |
WO2008043849A2 (en) | 2006-10-13 | 2008-04-17 | Basf Plant Science Gmbh | Plants with increased yield |
UA108733C2 (uk) * | 2006-12-12 | 2015-06-10 | Толерантна до гербіциду рослина соняшника | |
CA2982640A1 (en) | 2006-12-21 | 2008-07-03 | Basf Enzymes Llc | Amylases and glucoamylases, nucleic acids encoding them and methods for making and using them |
CA2691440A1 (en) | 2007-06-29 | 2009-01-08 | Pioneer Hi-Bred International, Inc. | Methods for altering the genome of a monocot plant cell |
US7980283B2 (en) * | 2008-01-16 | 2011-07-19 | Nextec Applications, Inc. | System and method for using a force model to control process configurations for the encapsulation of a web |
EP2119786A1 (de) | 2008-05-13 | 2009-11-18 | Expressive Research B.V. | Erhöhte Erzeugung von gesundheitsfördernden Zusammensetzungen in Pflanzen |
ES2607688T3 (es) | 2009-05-21 | 2017-04-03 | Basf Enzymes Llc | Fitasas, ácidos nucleicos que las codifican y métodos para su producción y uso |
WO2011074959A1 (en) | 2009-12-15 | 2011-06-23 | Edwin Henricus Antonius Holman | Transgenic ozone-resistant plants |
CA2793596A1 (en) | 2009-12-30 | 2011-07-07 | Pioneer Hi-Bred International, Inc. | Methods and compositions for targeted polynucleotide modification |
CN102892888A (zh) | 2009-12-30 | 2013-01-23 | 先锋国际良种公司 | 在植物中导入并调节表达基因的方法和组合物 |
US20110287936A1 (en) | 2010-04-23 | 2011-11-24 | E.I. Dupont De Nemours And Company | Gene switch compositions and methods of use |
NL2004624C2 (en) | 2010-04-28 | 2011-11-01 | Stichting Dienst Landbouwkundi | A new glycosyltransferase protein and its role in the metabolism of phenylpropanoid volatiles in tomato. |
BR112013008048A2 (pt) | 2010-10-06 | 2016-06-14 | Bp Corp North America Inc | polipeptídeos, composição, caldo de fermentação, métodos para sacrificar biomassa e para produzir etanol, ácido nucleico, vetor, células recombinante e hospedeira e métodos para produzir polipeptídeo e para gerar polipeptídeo de cbh i variante tolerante a produto e ácido nucleíco |
EP2689019A2 (de) | 2011-03-23 | 2014-01-29 | Pioneer Hi-Bred International Inc. | Verfahren zur herstellung eines komplexen transgenen trait locus |
CN104080914A (zh) | 2011-06-21 | 2014-10-01 | 先锋国际良种公司 | 产生雄性不育植物的组合物和方法 |
CN104219950B (zh) | 2012-02-01 | 2018-02-06 | 陶氏益农公司 | 人造的芸苔属衍生的叶绿体转运肽 |
US20140173775A1 (en) | 2012-12-13 | 2014-06-19 | Pioneer Hi-Bred International, Inc. | Methods and compositions for producing and selecting transgenic plants |
WO2014164775A1 (en) | 2013-03-11 | 2014-10-09 | Pioneer Hi-Bred International, Inc. | Methods and compositions to improve the spread of chemical signals in plants |
BR112015022742A2 (pt) | 2013-03-11 | 2018-11-27 | Pionner Hi Bred Int Inc | métodos e composições que empregam um domínio de estabilização dependente de sulfonilureia |
MX2016002118A (es) | 2013-08-22 | 2016-06-28 | Du Pont | Modificacion del genoma de plantas por medio del uso de sistemas de ácido ribonucléico (arn) guía/ endonucleasa cas y metodos de uso. |
AU2015288157A1 (en) | 2014-07-11 | 2017-01-19 | E. I. Du Pont De Nemours And Company | Compositions and methods for producing plants resistant to glyphosate herbicide |
EA038321B1 (ru) | 2014-11-06 | 2021-08-09 | Е.И. Дюпон Де Немур Энд Компани | Опосредуемая пептидом доставка направляемой рнк эндонуклеазы в клетки |
MX2017010746A (es) | 2015-02-25 | 2017-11-28 | Pioneer Hi Bred Int | Composicion y metodos para la expresion regulada de un complejo de arn guia/endonucleasa cas. |
AU2016263026A1 (en) | 2015-05-15 | 2017-11-09 | Pioneer Hi-Bred International, Inc. | Guide RNA/Cas endonuclease systems |
US9790490B2 (en) | 2015-06-18 | 2017-10-17 | The Broad Institute Inc. | CRISPR enzymes and systems |
AU2016279062A1 (en) | 2015-06-18 | 2019-03-28 | Omar O. Abudayyeh | Novel CRISPR enzymes and systems |
EP3666895A1 (de) | 2015-06-18 | 2020-06-17 | The Broad Institute, Inc. | Neuartige crispr-enzyme und systeme |
EP4144844A1 (de) | 2015-10-12 | 2023-03-08 | DuPont US Holding, LLC | Geschützte dna-schablonen zur genmodifizierung und erhöhten homologen rekombination in zellen und verfahren zur verwendung |
US20180282763A1 (en) | 2015-10-20 | 2018-10-04 | Pioneer Hi-Bred International, Inc. | Restoring function to a non-functional gene product via guided cas systems and methods of use |
EP3365441A1 (de) | 2015-10-22 | 2018-08-29 | The Broad Institute Inc. | Crispr-enzyme des typs vi-b und systeme |
EP3426778A1 (de) | 2016-03-11 | 2019-01-16 | Pioneer Hi-Bred International, Inc. | Neuartige cas9-systeme und verfahren zur verwendung |
EP3699281A1 (de) | 2016-03-11 | 2020-08-26 | Pioneer Hi-Bred International, Inc. | Neuartige cas9-systeme und verfahren zur verwendung |
WO2017155715A1 (en) | 2016-03-11 | 2017-09-14 | Pioneer Hi-Bred International, Inc. | Novel cas9 systems and methods of use |
US11286478B2 (en) | 2016-04-19 | 2022-03-29 | The Broad Institute, Inc. | Cpf1 complexes with reduced indel activity |
KR20190016970A (ko) | 2016-06-14 | 2019-02-19 | 파이어니어 하이 부렛드 인터내쇼날 인코포레이팃드 | 식물 게놈 변형을 위한 cpf1 엔도뉴클레아제의 용도 |
US11788083B2 (en) | 2016-06-17 | 2023-10-17 | The Broad Institute, Inc. | Type VI CRISPR orthologs and systems |
EP3472310A1 (de) | 2016-06-20 | 2019-04-24 | Pioneer Hi-Bred International, Inc. | Neuartige cas-systeme und verfahren zur verwendung |
US11066681B2 (en) | 2016-08-26 | 2021-07-20 | Lesaffre Et Compagnie | Production of itaconic acid |
WO2018069392A1 (en) | 2016-10-11 | 2018-04-19 | Vib Vzw | Means and methods for improved regeneration |
EP3596207B1 (de) | 2017-03-15 | 2023-12-20 | The Broad Institute, Inc. | Neuartige cas13b-orthologe-crispr-enzyme und systeme |
KR20200006054A (ko) | 2017-04-12 | 2020-01-17 | 더 브로드 인스티튜트, 인코퍼레이티드 | 신규 타입 vi crispr 오르소로그 및 시스템 |
WO2018197520A1 (en) | 2017-04-24 | 2018-11-01 | Dupont Nutrition Biosciences Aps | Methods and compositions of anti-crispr proteins for use in plants |
WO2018202800A1 (en) | 2017-05-03 | 2018-11-08 | Kws Saat Se | Use of crispr-cas endonucleases for plant genome engineering |
US11591601B2 (en) | 2017-05-05 | 2023-02-28 | The Broad Institute, Inc. | Methods for identification and modification of lncRNA associated with target genotypes and phenotypes |
CA3073848A1 (en) | 2017-09-21 | 2019-03-28 | The Broad Institute, Inc. | Systems, methods, and compositions for targeted nucleic acid editing |
EP3533878A1 (de) | 2018-02-28 | 2019-09-04 | Dutch DNA Biotech B.V. | Verfahren zur herstellung von 2-hydroxy-2-methylbutandisäure unter verwendung von aspergillus |
US10968257B2 (en) | 2018-04-03 | 2021-04-06 | The Broad Institute, Inc. | Target recognition motifs and uses thereof |
EP3833761A1 (de) | 2018-08-07 | 2021-06-16 | The Broad Institute, Inc. | Neuartige cas12b-enzyme und systeme |
GB201817464D0 (en) | 2018-10-26 | 2018-12-12 | Vib Vzw | Means and methods to increase organ size in plants |
EP3856897A1 (de) | 2018-11-05 | 2021-08-04 | Anadolu Universitesi | Rekombinantes glutathion-s-transferase-mu34-enzym (ttgstm34-8xhis) aus tetrahymena thermophila und dessen verwendungen |
CA3124110A1 (en) | 2018-12-17 | 2020-06-25 | The Broad Institute, Inc. | Crispr-associated transposase systems and methods of use thereof |
WO2020191102A1 (en) | 2019-03-18 | 2020-09-24 | The Broad Institute, Inc. | Type vii crispr proteins and systems |
US20220175848A1 (en) | 2019-04-01 | 2022-06-09 | The Broad Institute, Inc. | Methods and compositions for cell therapy |
US20220220469A1 (en) | 2019-05-20 | 2022-07-14 | The Broad Institute, Inc. | Non-class i multi-component nucleic acid targeting systems |
JP2022547570A (ja) | 2019-09-12 | 2022-11-14 | ザ・ブロード・インスティテュート・インコーポレイテッド | 操作済みのアデノ随伴ウイルスキャプシド |
US20230255185A1 (en) | 2021-09-20 | 2023-08-17 | Revivicor, Inc. | Multitransgenic pigs comprising ten genetic modifications for xenotransplantation |
WO2023196818A1 (en) | 2022-04-04 | 2023-10-12 | The Regents Of The University Of California | Genetic complementation compositions and methods |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MA20977A1 (fr) * | 1986-05-19 | 1987-12-31 | Ciba Geigy Ag | Plantes tolerant les herbicides contenant le gene de gluthathione S-Transferase |
US5073677A (en) * | 1986-09-26 | 1991-12-17 | Ciba-Geigy Corporation | Herbicidal tolerant plants containing rat glutathione S-transferase gene |
GB8901677D0 (en) * | 1989-01-26 | 1989-03-15 | Ici Plc | Hybrid seed production |
GB8901673D0 (en) * | 1989-01-26 | 1989-03-15 | Ici Plc | Gene switch |
-
1991
- 1991-07-02 GB GB919114259A patent/GB9114259D0/en active Pending
-
1992
- 1992-07-01 DE DE69232620T patent/DE69232620T2/de not_active Expired - Lifetime
- 1992-07-01 EP EP92913708A patent/EP0603190B1/de not_active Expired - Lifetime
- 1992-07-01 WO PCT/GB1992/001187 patent/WO1993001294A1/en active IP Right Grant
- 1992-07-01 US US08/170,294 patent/US5589614A/en not_active Expired - Lifetime
- 1992-07-01 AT AT92913708T patent/ATE218163T1/de not_active IP Right Cessation
- 1992-07-01 AU AU21959/92A patent/AU672362B2/en not_active Ceased
- 1992-07-01 DK DK92913708T patent/DK0603190T3/da active
- 1992-07-01 ES ES92913708T patent/ES2178637T3/es not_active Expired - Lifetime
- 1992-07-01 CA CA002111983A patent/CA2111983C/en not_active Expired - Lifetime
- 1992-07-01 JP JP50206493A patent/JP3377526B2/ja not_active Expired - Fee Related
-
1996
- 1996-06-17 US US08/664,855 patent/US5866792A/en not_active Expired - Lifetime
- 1996-08-16 AU AU62104/96A patent/AU690855B2/en not_active Ceased
-
2002
- 2002-09-04 JP JP2002258423A patent/JP2003174891A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
AU2195992A (en) | 1993-02-11 |
DE69232620T2 (de) | 2002-12-12 |
US5866792A (en) | 1999-02-02 |
CA2111983A1 (en) | 1993-01-21 |
GB9114259D0 (en) | 1991-08-21 |
WO1993001294A1 (en) | 1993-01-21 |
EP0603190B1 (de) | 2002-05-29 |
DE69232620D1 (de) | 2002-07-04 |
JPH06511385A (ja) | 1994-12-22 |
AU690855B2 (en) | 1998-04-30 |
EP0603190A1 (de) | 1994-06-29 |
ES2178637T3 (es) | 2003-01-01 |
US5589614A (en) | 1996-12-31 |
AU672362B2 (en) | 1996-10-03 |
JP3377526B2 (ja) | 2003-02-17 |
CA2111983C (en) | 2005-08-30 |
JP2003174891A (ja) | 2003-06-24 |
AU6210496A (en) | 1996-11-21 |
DK0603190T3 (da) | 2002-09-23 |
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