ATE214903T1 - Verwendung von perfluorkohlenwasserstoffen zur herstellung von potenzierungsmitteln für die ultraschallvermittelte hyperthermiebehandlung von biologischen geweben - Google Patents

Verwendung von perfluorkohlenwasserstoffen zur herstellung von potenzierungsmitteln für die ultraschallvermittelte hyperthermiebehandlung von biologischen geweben

Info

Publication number
ATE214903T1
ATE214903T1 AT92912400T AT92912400T ATE214903T1 AT E214903 T1 ATE214903 T1 AT E214903T1 AT 92912400 T AT92912400 T AT 92912400T AT 92912400 T AT92912400 T AT 92912400T AT E214903 T1 ATE214903 T1 AT E214903T1
Authority
AT
Austria
Prior art keywords
perfluorocarbons
agents
ultrasonic
potentizing
production
Prior art date
Application number
AT92912400T
Other languages
English (en)
Inventor
Therapeutics Inc Imarx
Original Assignee
Therapeutics Inc Imarx
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therapeutics Inc Imarx filed Critical Therapeutics Inc Imarx
Application granted granted Critical
Publication of ATE214903T1 publication Critical patent/ATE214903T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0052—Thermotherapy; Hyperthermia; Magnetic induction; Induction heating therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00681—Aspects not otherwise provided for
    • A61B2017/00707—Dummies, phantoms; Devices simulating patient or parts of patient
    • A61B2017/00716—Dummies, phantoms; Devices simulating patient or parts of patient simulating physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B17/22—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22082—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance
    • A61B2017/22088—Implements for squeezing-off ulcers or the like on inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; for invasive removal or destruction of calculus using mechanical vibrations; for removing obstructions in blood vessels, not otherwise provided for after introduction of a substance ultrasound absorbing, drug activated by ultrasound
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A61M2202/0476—Oxygenated solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy
    • A61N7/02—Localised ultrasound hyperthermia
    • A61N2007/025—Localised ultrasound hyperthermia interstitial

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
  • Saccharide Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT92912400T 1990-09-11 1992-05-04 Verwendung von perfluorkohlenwasserstoffen zur herstellung von potenzierungsmitteln für die ultraschallvermittelte hyperthermiebehandlung von biologischen geweben ATE214903T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/581,027 US5149319A (en) 1990-09-11 1990-09-11 Methods for providing localized therapeutic heat to biological tissues and fluids
PCT/US1992/003705 WO1993021889A1 (en) 1990-09-11 1992-05-04 Method for hyperthermic potentiation of tissue

Publications (1)

Publication Number Publication Date
ATE214903T1 true ATE214903T1 (de) 2002-04-15

Family

ID=24323604

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92912400T ATE214903T1 (de) 1990-09-11 1992-05-04 Verwendung von perfluorkohlenwasserstoffen zur herstellung von potenzierungsmitteln für die ultraschallvermittelte hyperthermiebehandlung von biologischen geweben

Country Status (7)

Country Link
US (1) US5149319A (de)
EP (1) EP0639067B1 (de)
JP (1) JPH07506032A (de)
AT (1) ATE214903T1 (de)
AU (2) AU678341B2 (de)
DE (1) DE69232518T2 (de)
WO (1) WO1993021889A1 (de)

Families Citing this family (248)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5776429A (en) 1989-12-22 1998-07-07 Imarx Pharmaceutical Corp. Method of preparing gas-filled microspheres using a lyophilized lipids
US5352435A (en) * 1989-12-22 1994-10-04 Unger Evan C Ionophore containing liposomes for ultrasound imaging
US20020150539A1 (en) 1989-12-22 2002-10-17 Unger Evan C. Ultrasound imaging and treatment
US5733572A (en) * 1989-12-22 1998-03-31 Imarx Pharmaceutical Corp. Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles
US6088613A (en) 1989-12-22 2000-07-11 Imarx Pharmaceutical Corp. Method of magnetic resonance focused surgical and therapeutic ultrasound
US5580575A (en) * 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US6001335A (en) 1989-12-22 1999-12-14 Imarx Pharmaceutical Corp. Contrasting agents for ultrasonic imaging and methods for preparing the same
US5542935A (en) 1989-12-22 1996-08-06 Imarx Pharmaceutical Corp. Therapeutic delivery systems related applications
US6551576B1 (en) 1989-12-22 2003-04-22 Bristol-Myers Squibb Medical Imaging, Inc. Container with multi-phase composition for use in diagnostic and therapeutic applications
US6146657A (en) 1989-12-22 2000-11-14 Imarx Pharmaceutical Corp. Gas-filled lipid spheres for use in diagnostic and therapeutic applications
US5305757A (en) * 1989-12-22 1994-04-26 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US5705187A (en) * 1989-12-22 1998-01-06 Imarx Pharmaceutical Corp. Compositions of lipids and stabilizing materials
US5585112A (en) 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
US5773024A (en) * 1989-12-22 1998-06-30 Imarx Pharmaceutical Corp. Container with multi-phase composition for use in diagnostic and therapeutic applications
US5922304A (en) 1989-12-22 1999-07-13 Imarx Pharmaceutical Corp. Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents
US5209720A (en) * 1989-12-22 1993-05-11 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes
US5656211A (en) * 1989-12-22 1997-08-12 Imarx Pharmaceutical Corp. Apparatus and method for making gas-filled vesicles of optimal size
US5469854A (en) * 1989-12-22 1995-11-28 Imarx Pharmaceutical Corp. Methods of preparing gas-filled liposomes
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
USRE39146E1 (en) 1990-04-02 2006-06-27 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
IN172208B (de) 1990-04-02 1993-05-01 Sint Sa
US7083778B2 (en) * 1991-05-03 2006-08-01 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6989141B2 (en) * 1990-05-18 2006-01-24 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US6613306B1 (en) 1990-04-02 2003-09-02 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US5578292A (en) * 1991-11-20 1996-11-26 Bracco International B.V. Long-lasting aqueous dispersions or suspensions of pressure-resistant gas-filled microvesicles and methods for the preparation thereof
US20010024638A1 (en) * 1992-11-02 2001-09-27 Michel Schneider Stable microbubble suspensions as enhancement agents for ultrasound echography and dry formulations thereof
US20040208826A1 (en) * 1990-04-02 2004-10-21 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
US20030194376A1 (en) * 1990-05-18 2003-10-16 Bracco International B.V. Ultrasound contrast agents and methods of making and using them
CA2063529A1 (en) * 1991-03-22 1992-09-23 Katsuro Tachibana Booster for therapy of diseases with ultrasound and pharmaceutical liquid composition containing the same
US5874062A (en) 1991-04-05 1999-02-23 Imarx Pharmaceutical Corp. Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents
US5205290A (en) * 1991-04-05 1993-04-27 Unger Evan C Low density microspheres and their use as contrast agents for computed tomography
US6723303B1 (en) 1991-09-17 2004-04-20 Amersham Health, As Ultrasound contrast agents including protein stabilized microspheres of perfluoropropane, perfluorobutane or perfluoropentane
MX9205298A (es) * 1991-09-17 1993-05-01 Steven Carl Quay Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido
US5409688A (en) * 1991-09-17 1995-04-25 Sonus Pharmaceuticals, Inc. Gaseous ultrasound contrast media
JPH0596012A (ja) * 1991-10-07 1993-04-20 Olympus Optical Co Ltd 温熱治療装置
FR2685732B1 (fr) * 1991-12-31 1994-02-25 Snecma Aube de turbomachine en materiau composite.
IL104084A (en) 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
IL108416A (en) 1993-01-25 1998-10-30 Sonus Pharma Inc Phase shift colloids as ultrasound contrast agents
US5855865A (en) * 1993-07-02 1999-01-05 Molecular Biosystems, Inc. Method for making encapsulated gas microspheres from heat denatured protein in the absence of oxygen gas
EP0711179B2 (de) 1993-07-30 2010-09-01 IMCOR Pharmaceutical Co. Stabilisierte mikrogasblaeschen-zusammensetzungen für echografie
US5798091A (en) * 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
ATE234638T1 (de) * 1993-12-15 2003-04-15 Bracco Research Sa Gas-mischungen verwendbar als ultraschallkontrastmittel
US5736121A (en) * 1994-05-23 1998-04-07 Imarx Pharmaceutical Corp. Stabilized homogenous suspensions as computed tomography contrast agents
US5509896A (en) * 1994-09-09 1996-04-23 Coraje, Inc. Enhancement of thrombolysis with external ultrasound
US5540909A (en) * 1994-09-28 1996-07-30 Alliance Pharmaceutical Corp. Harmonic ultrasound imaging with microbubbles
US6743779B1 (en) 1994-11-29 2004-06-01 Imarx Pharmaceutical Corp. Methods for delivering compounds into a cell
US5590651A (en) * 1995-01-17 1997-01-07 Temple University - Of The Commonwealth System Of Higher Education Breathable liquid elimination analysis
US5830430A (en) 1995-02-21 1998-11-03 Imarx Pharmaceutical Corp. Cationic lipids and the use thereof
US6176842B1 (en) * 1995-03-08 2001-01-23 Ekos Corporation Ultrasound assembly for use with light activated drugs
JP3955897B2 (ja) * 1995-03-08 2007-08-08 克郎 立花 超音波治療装置
JPH11509747A (ja) * 1995-05-15 1999-08-31 コラジェ・インコーポレーテッド 超音波血栓崩壊の増強
US5558092A (en) * 1995-06-06 1996-09-24 Imarx Pharmaceutical Corp. Methods and apparatus for performing diagnostic and therapeutic ultrasound simultaneously
US5997898A (en) 1995-06-06 1999-12-07 Imarx Pharmaceutical Corp. Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery
US6033645A (en) 1996-06-19 2000-03-07 Unger; Evan C. Methods for diagnostic imaging by regulating the administration rate of a contrast agent
US6231834B1 (en) 1995-06-07 2001-05-15 Imarx Pharmaceutical Corp. Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same
US6139819A (en) 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US5741248A (en) * 1995-06-07 1998-04-21 Temple University-Of The Commonwealth System Of Higher Education Fluorochemical liquid augmented cryosurgery
US5804162A (en) 1995-06-07 1998-09-08 Alliance Pharmaceutical Corp. Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients
US6821506B2 (en) * 1995-06-08 2004-11-23 Barnes-Jewish Hospital Site specific binding system, imaging compositions and methods
US20050089958A1 (en) * 1996-01-09 2005-04-28 Genentech, Inc. Apo-2 ligand
US6998116B1 (en) * 1996-01-09 2006-02-14 Genentech, Inc. Apo-2 ligand
US5840276A (en) * 1996-01-11 1998-11-24 Apfel Enterprises, Inc. Activatable infusable dispersions containing drops of a superheated liquid for methods of therapy and diagnosis
DE69729088T2 (de) * 1996-03-05 2005-05-12 Acusphere, Inc., Cambridge Mikroverkapselte fluorierte gase zur anwendung als bilderzeugende mittel
US5611344A (en) * 1996-03-05 1997-03-18 Acusphere, Inc. Microencapsulated fluorinated gases for use as imaging agents
US5861175A (en) * 1996-03-15 1999-01-19 Alliance Pharmaceutical Corp. Use of fluorocarbons for diagnosis and treatment of articular disorders
US5676692A (en) * 1996-03-28 1997-10-14 Indianapolis Center For Advanced Research, Inc. Focussed ultrasound tissue treatment method
CA2252617A1 (en) 1996-05-01 1997-11-06 Imarx Pharmaceutical Corp. Methods for delivering compounds into a cell
BE1010407A4 (fr) * 1996-07-04 1998-07-07 Undatim Ultrasonics Procede et installation de traitement des eaux.
US5837221A (en) * 1996-07-29 1998-11-17 Acusphere, Inc. Polymer-lipid microencapsulated gases for use as imaging agents
US6414139B1 (en) 1996-09-03 2002-07-02 Imarx Therapeutics, Inc. Silicon amphiphilic compounds and the use thereof
DE69718519T2 (de) 1996-09-11 2003-11-06 Imarx Pharmaceutical Corp., Tucson Verbesserte verfahren zur diagnostischen bilderzeugung unter verwendung eines kontrastmittels und eines vasodilators
US5846517A (en) 1996-09-11 1998-12-08 Imarx Pharmaceutical Corp. Methods for diagnostic imaging using a renal contrast agent and a vasodilator
US6451044B1 (en) * 1996-09-20 2002-09-17 Board Of Regents, The University Of Texas System Method and apparatus for heating inflammed tissue
US6090800A (en) 1997-05-06 2000-07-18 Imarx Pharmaceutical Corp. Lipid soluble steroid prodrugs
US6143276A (en) 1997-03-21 2000-11-07 Imarx Pharmaceutical Corp. Methods for delivering bioactive agents to regions of elevated temperatures
US6537246B1 (en) 1997-06-18 2003-03-25 Imarx Therapeutics, Inc. Oxygen delivery agents and uses for the same
US6120751A (en) 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6676626B1 (en) 1998-05-01 2004-01-13 Ekos Corporation Ultrasound assembly with increased efficacy
US6582392B1 (en) 1998-05-01 2003-06-24 Ekos Corporation Ultrasound assembly for use with a catheter
US6723063B1 (en) 1998-06-29 2004-04-20 Ekos Corporation Sheath for use with an ultrasound element
US7452551B1 (en) 2000-10-30 2008-11-18 Imarx Therapeutics, Inc. Targeted compositions for diagnostic and therapeutic use
US6416740B1 (en) 1997-05-13 2002-07-09 Bristol-Myers Squibb Medical Imaging, Inc. Acoustically active drug delivery systems
WO1998055605A1 (en) * 1997-06-04 1998-12-10 William Drewes Method of destroying cells via resonant destruction of intracellular structures
US5954675A (en) * 1997-07-07 1999-09-21 Dellagatta; Enrico Michael Method of ultrasonic therapy
US6548047B1 (en) 1997-09-15 2003-04-15 Bristol-Myers Squibb Medical Imaging, Inc. Thermal preactivation of gaseous precursor filled compositions
US6623430B1 (en) 1997-10-14 2003-09-23 Guided Therapy Systems, Inc. Method and apparatus for safety delivering medicants to a region of tissue using imaging, therapy and temperature monitoring ultrasonic system
US6050943A (en) 1997-10-14 2000-04-18 Guided Therapy Systems, Inc. Imaging, therapy, and temperature monitoring ultrasonic system
US6123923A (en) 1997-12-18 2000-09-26 Imarx Pharmaceutical Corp. Optoacoustic contrast agents and methods for their use
US20010003580A1 (en) 1998-01-14 2001-06-14 Poh K. Hui Preparation of a lipid blend and a phospholipid suspension containing the lipid blend
JPH11244283A (ja) * 1998-03-05 1999-09-14 Ge Yokogawa Medical Systems Ltd 超音波撮像方法および装置
US6074352A (en) * 1998-03-26 2000-06-13 Brigham And Women's Hospital Method for the treatment of joint diseases characterized by unwanted pannus
US6685640B1 (en) * 1998-03-30 2004-02-03 Focus Surgery, Inc. Ablation system
WO1999049788A1 (en) * 1998-03-30 1999-10-07 Focus Surgery, Inc. Ablation system
IL127967A (en) * 1999-01-07 2004-05-12 Moris Topaz Flushing solution for surgery using ultrasound energy
US20050061335A1 (en) * 1999-01-07 2005-03-24 Morris Topaz Irrigation solution for use in ultrasound energy assisted surgery
ATE262891T1 (de) * 1999-01-07 2004-04-15 Moris Topaz Biokompatible injektierbare wässerige lösung zur verwendung bei ultraschallenergieunterstützter chirurgie
DE19940220B4 (de) 1999-08-19 2007-05-03 Magforce Nanotechnologies Ag Medizinisches Präparat zur Behandlung von Arthrose, Arthritis und anderen rheumatischen Gelenkerkrankungen
KR20010088022A (ko) * 2000-03-10 2001-09-26 모리스 토파즈 초음파 에너지 보조된 수술용 생체적합성 주사제 수성 용액
US6514221B2 (en) * 2000-07-27 2003-02-04 Brigham And Women's Hospital, Inc. Blood-brain barrier opening
US7914453B2 (en) 2000-12-28 2011-03-29 Ardent Sound, Inc. Visual imaging system for ultrasonic probe
AU2007201577B2 (en) * 2001-01-30 2008-10-02 Barnes-Jewish Hospital Enhanced ultrasound detection with temperature-dependent contrast agents
US7179449B2 (en) * 2001-01-30 2007-02-20 Barnes-Jewish Hospital Enhanced ultrasound detection with temperature-dependent contrast agents
US20030013972A1 (en) 2001-05-29 2003-01-16 Makin Inder Raj. S. Treatment of lung lesions using ultrasound
US7211044B2 (en) 2001-05-29 2007-05-01 Ethicon Endo-Surgery, Inc. Method for mapping temperature rise using pulse-echo ultrasound
US7846096B2 (en) * 2001-05-29 2010-12-07 Ethicon Endo-Surgery, Inc. Method for monitoring of medical treatment using pulse-echo ultrasound
JP4660024B2 (ja) * 2001-06-26 2011-03-30 帝人株式会社 Ｍｍｐ活性低下装置及び方法
IL144661A0 (en) 2001-07-31 2002-05-23 Medisim Ltd A method for detection of cancer using a thermal enhancement agent, and non-invasive thermal monitoring
AU2002359576A1 (en) 2001-12-03 2003-06-17 Ekos Corporation Catheter with multiple ultrasound radiating members
JP4167178B2 (ja) * 2001-12-14 2008-10-15 イコス コーポレイション 血液の流れの再開の判定
US7101571B2 (en) * 2002-02-14 2006-09-05 Peyman Gholam A Method and composition for hyperthermally treating cells
US8808268B2 (en) 2002-02-14 2014-08-19 Gholam A. Peyman Method and composition for hyperthermally treating cells
US8709488B2 (en) 2002-02-14 2014-04-29 Gholam A. Peyman Method and composition for hyperthermally treating cells
US8932636B2 (en) 2002-02-14 2015-01-13 Gholam A. Peyman Method and composition for hyperthermally treating cells
US8119165B2 (en) 2002-02-14 2012-02-21 Peyman Gholam A Method and composition for hyperthermally treating cells
US9233157B2 (en) 2002-02-14 2016-01-12 Gholam A. Peyman Method and composition for hyperthermally treating cells
US8137698B2 (en) * 2002-02-14 2012-03-20 Peyman Gholam A Method and composition for hyperthermally treating cells
US9302087B2 (en) 2002-02-14 2016-04-05 Gholam A. Peyman Method and composition for hyperthermally treating cells
US9393396B2 (en) 2002-02-14 2016-07-19 Gholam A. Peyman Method and composition for hyperthermally treating cells
US9017729B2 (en) 2002-02-14 2015-04-28 Gholam A. Peyman Method and composition for hyperthermally treating cells
US9320813B2 (en) 2002-02-14 2016-04-26 Gholam A. Peyman Method and composition for hyperthermally treating cells
US9289491B2 (en) 2002-02-14 2016-03-22 Gholam A. Peyman Method and composition for hyperthermally treating cells
US8801690B2 (en) 2002-02-14 2014-08-12 Gholam A. Peyman Method and composition for hyperthermally treating cells
US8668935B2 (en) 2002-02-14 2014-03-11 Gholam A. Peyman Method and composition for hyperthermally treating cells
US8795251B2 (en) 2002-02-14 2014-08-05 Gholam A. Peyman Method and composition for hyperthermally treating cells
US7964214B2 (en) * 2006-07-13 2011-06-21 Peyman Gholam A Method and composition for hyperthermally treating cells in the eye with simultaneous imaging
US8481082B2 (en) 2002-02-14 2013-07-09 Gholam A. Peyman Method and composition for hyperthermally treating cells
US8226629B1 (en) 2002-04-01 2012-07-24 Ekos Corporation Ultrasonic catheter power control
WO2004023981A2 (en) * 2002-09-11 2004-03-25 Duke University Methods and compositions for blood pool identification, drug distribution quantification and drug release verification
US7769423B2 (en) * 2002-09-11 2010-08-03 Duke University MRI imageable liposomes for the evaluation of treatment efficacy, thermal distribution, and demonstration of dose painting
US7357937B2 (en) * 2002-09-24 2008-04-15 Therox, Inc. Perfluorocarbon emulsions with non-fluorinated surfactants
US6921371B2 (en) 2002-10-14 2005-07-26 Ekos Corporation Ultrasound radiating members for catheter
US20030191396A1 (en) * 2003-03-10 2003-10-09 Sanghvi Narendra T Tissue treatment method and apparatus
DE10315538A1 (de) * 2003-04-04 2004-10-21 Siemens Ag Teilchen mit einer Membran
US7048863B2 (en) * 2003-07-08 2006-05-23 Ashland Licensing And Intellectual Property Llc Device and process for treating cutting fluids using ultrasound
CN100475275C (zh) * 2004-01-05 2009-04-08 董永华 肿瘤血管栓塞剂及其储存和释放装置
CA2553165A1 (en) * 2004-01-29 2005-08-11 Ekos Corporation Method and apparatus for detecting vascular conditions with a catheter
US7341569B2 (en) * 2004-01-30 2008-03-11 Ekos Corporation Treatment of vascular occlusions using ultrasonic energy and microbubbles
US7662114B2 (en) * 2004-03-02 2010-02-16 Focus Surgery, Inc. Ultrasound phased arrays
US7494467B2 (en) 2004-04-16 2009-02-24 Ethicon Endo-Surgery, Inc. Medical system having multiple ultrasound transducers or an ultrasound transducer and an RF electrode
US7883468B2 (en) * 2004-05-18 2011-02-08 Ethicon Endo-Surgery, Inc. Medical system having an ultrasound source and an acoustic coupling medium
US7951095B2 (en) 2004-05-20 2011-05-31 Ethicon Endo-Surgery, Inc. Ultrasound medical system
US7473250B2 (en) 2004-05-21 2009-01-06 Ethicon Endo-Surgery, Inc. Ultrasound medical system and method
US8012457B2 (en) 2004-06-04 2011-09-06 Acusphere, Inc. Ultrasound contrast agent dosage formulation
US7806839B2 (en) * 2004-06-14 2010-10-05 Ethicon Endo-Surgery, Inc. System and method for ultrasound therapy using grating lobes
EP1761284B1 (de) 2004-06-23 2012-08-29 Ashland Licensing and Intellectual Property LLC Verfahren und vorrichtung zur ultraschall behandlung von bei elektrobeschichtungsverfahren verwendeten flüssigkeiten
US9011336B2 (en) 2004-09-16 2015-04-21 Guided Therapy Systems, Llc Method and system for combined energy therapy profile
US7393325B2 (en) 2004-09-16 2008-07-01 Guided Therapy Systems, L.L.C. Method and system for ultrasound treatment with a multi-directional transducer
US7824348B2 (en) 2004-09-16 2010-11-02 Guided Therapy Systems, L.L.C. System and method for variable depth ultrasound treatment
US20130046209A1 (en) 2011-07-10 2013-02-21 Guided Therapy Systems, Llc Systems and methods for improving an outside appearance of skin using ultrasound as an energy source
US10864385B2 (en) 2004-09-24 2020-12-15 Guided Therapy Systems, Llc Rejuvenating skin by heating tissue for cosmetic treatment of the face and body
US8444562B2 (en) 2004-10-06 2013-05-21 Guided Therapy Systems, Llc System and method for treating muscle, tendon, ligament and cartilage tissue
US8535228B2 (en) 2004-10-06 2013-09-17 Guided Therapy Systems, Llc Method and system for noninvasive face lifts and deep tissue tightening
US7530958B2 (en) * 2004-09-24 2009-05-12 Guided Therapy Systems, Inc. Method and system for combined ultrasound treatment
US9694212B2 (en) 2004-10-06 2017-07-04 Guided Therapy Systems, Llc Method and system for ultrasound treatment of skin
US7758524B2 (en) 2004-10-06 2010-07-20 Guided Therapy Systems, L.L.C. Method and system for ultra-high frequency ultrasound treatment
KR20210068607A (ko) 2004-10-06 2021-06-09 가이디드 테라피 시스템스, 엘.엘.씨. 초음파 치료 시스템
US9827449B2 (en) 2004-10-06 2017-11-28 Guided Therapy Systems, L.L.C. Systems for treating skin laxity
US8690779B2 (en) 2004-10-06 2014-04-08 Guided Therapy Systems, Llc Noninvasive aesthetic treatment for tightening tissue
US8133180B2 (en) 2004-10-06 2012-03-13 Guided Therapy Systems, L.L.C. Method and system for treating cellulite
US20060111744A1 (en) 2004-10-13 2006-05-25 Guided Therapy Systems, L.L.C. Method and system for treatment of sweat glands
WO2006042163A2 (en) 2004-10-06 2006-04-20 Guided Therapy Systems, L.L.C. Method and system for cosmetic enhancement
US11883688B2 (en) 2004-10-06 2024-01-30 Guided Therapy Systems, Llc Energy based fat reduction
US11235179B2 (en) 2004-10-06 2022-02-01 Guided Therapy Systems, Llc Energy based skin gland treatment
US11724133B2 (en) 2004-10-07 2023-08-15 Guided Therapy Systems, Llc Ultrasound probe for treatment of skin
US11207548B2 (en) 2004-10-07 2021-12-28 Guided Therapy Systems, L.L.C. Ultrasound probe for treating skin laxity
US7452357B2 (en) 2004-10-22 2008-11-18 Ethicon Endo-Surgery, Inc. System and method for planning treatment of tissue
US7833221B2 (en) 2004-10-22 2010-11-16 Ethicon Endo-Surgery, Inc. System and method for treatment of tissue using the tissue as a fiducial
US8364256B2 (en) * 2004-11-15 2013-01-29 Coraje, Inc. Method and apparatus of removal of intravascular blockages
ES2440778T3 (es) 2004-11-17 2014-01-30 Ashland Licensing And Intellectual Property Llc Método para tratar fluidos refrigerantes utilizados en la fabricación de neumáticos
US20060264809A1 (en) * 2005-04-12 2006-11-23 Hansmann Douglas R Ultrasound catheter with cavitation promoting surface
EP1875327A2 (de) 2005-04-25 2008-01-09 Guided Therapy Systems, L.L.C. Verfahren und system zum verbessern der computerperipheriesicherheit
US8038631B1 (en) * 2005-06-01 2011-10-18 Sanghvi Narendra T Laparoscopic HIFU probe
EP1904179A2 (de) * 2005-06-07 2008-04-02 Koninklijke Philips Electronics N.V. Verfahren und gerät zur ultraschall-arzneiabgabe und wärmetherapie mit phasenkonvertierbaren flüssigkeiten
US20070038096A1 (en) * 2005-07-06 2007-02-15 Ralf Seip Method of optimizing an ultrasound transducer
US20070010805A1 (en) 2005-07-08 2007-01-11 Fedewa Russell J Method and apparatus for the treatment of tissue
US9011473B2 (en) 2005-09-07 2015-04-21 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9358033B2 (en) 2005-09-07 2016-06-07 Ulthera, Inc. Fluid-jet dissection system and method for reducing the appearance of cellulite
US8518069B2 (en) 2005-09-07 2013-08-27 Cabochon Aesthetics, Inc. Dissection handpiece and method for reducing the appearance of cellulite
US9486274B2 (en) * 2005-09-07 2016-11-08 Ulthera, Inc. Dissection handpiece and method for reducing the appearance of cellulite
EP1928540A4 (de) * 2005-09-07 2010-03-10 The Foundry Inc Gerät und verfahren zur unterbrechung von subkutanen strukturen
US7967763B2 (en) 2005-09-07 2011-06-28 Cabochon Aesthetics, Inc. Method for treating subcutaneous tissues
US10548659B2 (en) 2006-01-17 2020-02-04 Ulthera, Inc. High pressure pre-burst for improved fluid delivery
US20080014627A1 (en) * 2005-12-02 2008-01-17 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US20080200864A1 (en) * 2005-12-02 2008-08-21 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US20080195036A1 (en) * 2005-12-02 2008-08-14 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US20080197517A1 (en) * 2005-12-02 2008-08-21 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US7885793B2 (en) 2007-05-22 2011-02-08 International Business Machines Corporation Method and system for developing a conceptual model to facilitate generating a business-aligned information technology solution
US20080200863A1 (en) * 2005-12-02 2008-08-21 Cabochon Aesthetics, Inc. Devices and methods for selectively lysing cells
US9248317B2 (en) * 2005-12-02 2016-02-02 Ulthera, Inc. Devices and methods for selectively lysing cells
EP2015846A2 (de) 2006-04-24 2009-01-21 Ekos Corporation Ultraschalltherapiesystem
WO2007127958A2 (en) * 2006-04-27 2007-11-08 Barnes-Jewish Hospital Detection and imaging of target tissue
EP2020988B1 (de) 2006-04-28 2017-08-16 Children's Hospital Medical Center Zusammensetzungen mit fusogenen proteinen oder polypeptiden aus prosaposin zur anwendung auf transmembrane wirkstofffreisetzungssysteme
US9566454B2 (en) 2006-09-18 2017-02-14 Guided Therapy Systems, Llc Method and sysem for non-ablative acne treatment and prevention
US7559905B2 (en) 2006-09-21 2009-07-14 Focus Surgery, Inc. HIFU probe for treating tissue with in-line degassing of fluid
US8192363B2 (en) 2006-10-27 2012-06-05 Ekos Corporation Catheter with multiple ultrasound radiating members
US9050448B2 (en) * 2006-12-19 2015-06-09 Cedars-Sinai Medical Center Ultrasonic bath to increase tissue perfusion
US10182833B2 (en) 2007-01-08 2019-01-22 Ekos Corporation Power parameters for ultrasonic catheter
WO2008137942A1 (en) 2007-05-07 2008-11-13 Guided Therapy Systems, Llc. Methods and systems for modulating medicants using acoustic energy
US20150174388A1 (en) 2007-05-07 2015-06-25 Guided Therapy Systems, Llc Methods and Systems for Ultrasound Assisted Delivery of a Medicant to Tissue
WO2009002881A1 (en) 2007-06-22 2008-12-31 Ekos Corporation Method and apparatus for treatment of intracranial hemorrhages
US8235902B2 (en) 2007-09-11 2012-08-07 Focus Surgery, Inc. System and method for tissue change monitoring during HIFU treatment
US8439940B2 (en) 2010-12-22 2013-05-14 Cabochon Aesthetics, Inc. Dissection handpiece with aspiration means for reducing the appearance of cellulite
EP2227147A1 (de) 2007-11-21 2010-09-15 Focus Surgery, Inc. Verfahren zur diagnose und behandlung von tumoren mit fokussiertem hochintensitäts-ultraschall
KR102087909B1 (ko) 2008-06-06 2020-03-12 얼테라, 인크 코스메틱 치료 시스템
US12102473B2 (en) 2008-06-06 2024-10-01 Ulthera, Inc. Systems for ultrasound treatment
GB0811856D0 (en) * 2008-06-27 2008-07-30 Ucl Business Plc Magnetic microbubbles, methods of preparing them and their uses
EP2382010A4 (de) 2008-12-24 2014-05-14 Guided Therapy Systems Llc Verfahren und systeme zur fettreduzierung und/oder behandlung von cellulite
US9358064B2 (en) 2009-08-07 2016-06-07 Ulthera, Inc. Handpiece and methods for performing subcutaneous surgery
US11096708B2 (en) 2009-08-07 2021-08-24 Ulthera, Inc. Devices and methods for performing subcutaneous surgery
US8715186B2 (en) 2009-11-24 2014-05-06 Guided Therapy Systems, Llc Methods and systems for generating thermal bubbles for improved ultrasound imaging and therapy
US9351943B2 (en) * 2010-07-01 2016-05-31 Matthew T. McLeay Anti-fibroblastic fluorochemical emulsion therapies
US9504446B2 (en) 2010-08-02 2016-11-29 Guided Therapy Systems, Llc Systems and methods for coupling an ultrasound source to tissue
EP2600937B8 (de) 2010-08-02 2024-03-06 Guided Therapy Systems, L.L.C. Systeme zur behandlung akuter und / oder chronischer verletzungen der weichteile
US8857438B2 (en) 2010-11-08 2014-10-14 Ulthera, Inc. Devices and methods for acoustic shielding
US11458290B2 (en) 2011-05-11 2022-10-04 Ekos Corporation Ultrasound system
KR20190080967A (ko) 2011-07-11 2019-07-08 가이디드 테라피 시스템스, 엘.엘.씨. 조직에 초음파원을 연결하는 시스템 및 방법
US20150305924A1 (en) * 2011-07-18 2015-10-29 Kenji Ryotokuji Stimulus method for releasing stress, and stress-free medical treatment method by the stimulus method
US9263663B2 (en) 2012-04-13 2016-02-16 Ardent Sound, Inc. Method of making thick film transducer arrays
US9510802B2 (en) 2012-09-21 2016-12-06 Guided Therapy Systems, Llc Reflective ultrasound technology for dermatological treatments
CN113648551B (zh) 2013-03-08 2025-03-25 奥赛拉公司 用于多焦点超声治疗的装置和方法
US10561862B2 (en) 2013-03-15 2020-02-18 Guided Therapy Systems, Llc Ultrasound treatment device and methods of use
US10064940B2 (en) 2013-12-11 2018-09-04 Siva Therapeutics Inc. Multifunctional radiation delivery apparatus and method
CN106470735B (zh) 2014-04-18 2019-09-20 奥赛拉公司 带式换能器超声治疗
US10092742B2 (en) 2014-09-22 2018-10-09 Ekos Corporation Catheter system
AU2015374286B2 (en) 2014-12-31 2021-11-18 Lantheus Medical Imaging, Inc. Lipid-encapsulated gas microsphere compositions and related methods
EP3307388B1 (de) 2015-06-10 2022-06-22 Ekos Corporation Ultraschallkatheter
US9849092B2 (en) 2015-12-21 2017-12-26 Gholam A. Peyman Early cancer detection and enhanced immunotherapy
US11090385B2 (en) 2015-12-21 2021-08-17 Gholam A. Peyman Early cancer detection and enhanced immunotherapy
US11433260B2 (en) 2015-12-21 2022-09-06 Gholam A. Peyman Cancer treatment methods using thermotherapy and/or enhanced immunotherapy
US10136820B2 (en) 2015-12-21 2018-11-27 Gholam A. Peyman Method to visualize very early stage neoplasm or other lesions
US11660229B2 (en) 2015-12-21 2023-05-30 Gholam A. Peyman Cancer treatment methods using thermotherapy and/or enhanced immunotherapy
US10300121B2 (en) 2015-12-21 2019-05-28 Gholam A. Peyman Early cancer detection and enhanced immunotherapy
KR102707101B1 (ko) 2016-01-18 2024-09-13 얼테라, 인크 환형 초음파 어레이가 가요성 인쇄 회로 기판에 지엽적으로 전기적으로 연결된 컴팩트한 초음파 디바이스 및 그 조립 방법
US10376600B2 (en) 2016-03-03 2019-08-13 Gholam A. Peyman Early disease detection and therapy
US11419543B1 (en) 2016-03-03 2022-08-23 Gholam A. Peyman Early disease detection and therapy
IL262647B2 (en) 2016-05-04 2023-03-01 Lantheus Medical Imaging Inc Methods and devices for preparing sharpness factors for ultrasound
US20190201556A1 (en) 2016-05-16 2019-07-04 Mtm Research, Llc Fluorochemical targeted therapies
US9789210B1 (en) 2016-07-06 2017-10-17 Lantheus Medical Imaging, Inc. Methods for making ultrasound contrast agents
IL301765B2 (en) 2016-08-16 2025-01-01 Ulthera Inc Systems and methods for cosmetic skin treatment using ultrasound
EP3658134A4 (de) 2017-07-24 2021-05-05 Pharmosa Biopharm Inc. Liposomzusammensetzungen mit schwachsauren arzneimitteln und verwendungen davon
TWI797235B (zh) 2018-01-26 2023-04-01 美商奧賽拉公司 用於多個維度中的同時多聚焦超音治療的系統和方法
US11944849B2 (en) 2018-02-20 2024-04-02 Ulthera, Inc. Systems and methods for combined cosmetic treatment of cellulite with ultrasound
CA3252800A1 (en) 2018-05-07 2025-10-30 Mtm Research, Llc Photodynamic compositions and methods of use
IL321967A (en) 2018-11-30 2025-09-01 Ulthera Inc Systems and methods for increasing the effectiveness of ultrasound therapy
CA3137928A1 (en) 2019-07-15 2021-01-21 Ulthera, Inc. Systems and methods for measuring elasticity with imaging of ultrasound multi-focus shearwaves in multiple dimensions
US11998765B2 (en) 2020-09-29 2024-06-04 Cancer Rx, LLC Cancer imaging methods and cancer treatment methods using thermotherapy and drug delivery

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4276885A (en) * 1979-05-04 1981-07-07 Rasor Associates, Inc Ultrasonic image enhancement
US4315514A (en) * 1980-05-08 1982-02-16 William Drewes Method and apparatus for selective cell destruction
US4681119A (en) * 1980-11-17 1987-07-21 Schering Aktiengesellschaft Method of production and use of microbubble precursors
ATE17311T1 (de) * 1980-11-17 1986-01-15 Schering Ag Praeparat zur erzeugung von mikroblaeschen.
US4657756A (en) * 1980-11-17 1987-04-14 Schering Aktiengesellschaft Microbubble precursors and apparatus for their production and use
US4442843A (en) * 1980-11-17 1984-04-17 Schering, Ag Microbubble precursors and methods for their production and use
US4533254A (en) * 1981-04-17 1985-08-06 Biotechnology Development Corporation Apparatus for forming emulsions
EP0068961A3 (de) * 1981-06-26 1983-02-02 Thomson-Csf Vorrichtung zur lokalen Erwärmung von biologischen Gewebe
US4569836A (en) * 1981-08-27 1986-02-11 Gordon Robert T Cancer treatment by intracellular hyperthermia
DE3141641A1 (de) * 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen Ultraschall-kontrastmittel und dessen herstellung
EP0111386B1 (de) * 1982-10-26 1987-11-19 University Of Aberdeen Ultraschallanlage zur Hyperthermie
US4718433A (en) * 1983-01-27 1988-01-12 Feinstein Steven B Contrast agents for ultrasonic imaging
US4900540A (en) * 1983-06-20 1990-02-13 Trustees Of The University Of Massachusetts Lipisomes containing gas for ultrasound detection
FR2563725B1 (fr) * 1984-05-03 1988-07-15 Dory Jacques Appareil d'examen et de localisation de tumeurs par ultrasons muni d'un dispositif de traitement localise par hyperthermie
US4728575A (en) * 1984-04-27 1988-03-01 Vestar, Inc. Contrast agents for NMR imaging
CA1264668A (en) * 1984-06-20 1990-01-23 Pieter R. Cullis Extrusion techniques for producing liposomes
US4620546A (en) * 1984-06-30 1986-11-04 Kabushiki Kaisha Toshiba Ultrasound hyperthermia apparatus
US4689986A (en) * 1985-03-13 1987-09-01 The University Of Michigan Variable frequency gas-bubble-manipulating apparatus and method
US4684479A (en) * 1985-08-14 1987-08-04 Arrigo Joseph S D Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures
US4927623A (en) * 1986-01-14 1990-05-22 Alliance Pharmaceutical Corp. Dissolution of gas in a fluorocarbon liquid
US4865836A (en) * 1986-01-14 1989-09-12 Fluoromed Pharmaceutical, Inc. Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport
US4737323A (en) * 1986-02-13 1988-04-12 Liposome Technology, Inc. Liposome extrusion method
IL79559A0 (en) * 1986-07-29 1986-10-31 Univ Ramot Contrast agents for nmr medical imaging
US4728578A (en) * 1986-08-13 1988-03-01 The Lubrizol Corporation Compositions containing basic metal salts and/or non-Newtonian colloidal disperse systems and vinyl aromatic containing polymers
DE3741199A1 (de) * 1987-12-02 1989-08-17 Schering Ag Verwendung von ultraschallkontrastmitteln fuer die ultraschall-lithotripsie
US4844882A (en) * 1987-12-29 1989-07-04 Molecular Biosystems, Inc. Concentrated stabilized microbubble-type ultrasonic imaging agent
US4898734A (en) * 1988-02-29 1990-02-06 Massachusetts Institute Of Technology Polymer composite for controlled release or membrane formation
US4893624A (en) * 1988-06-21 1990-01-16 Massachusetts Institute Of Technology Diffuse focus ultrasound hyperthermia system
US5158071A (en) * 1988-07-01 1992-10-27 Hitachi, Ltd. Ultrasonic apparatus for therapeutical use
JP2935519B2 (ja) * 1989-08-28 1999-08-16 シーキンス，ケイ・マイケル 超音波および／またはペルフルオロカーボン液での対流を介する肺癌高熱治療
US5209720A (en) * 1989-12-22 1993-05-11 Unger Evan C Methods for providing localized therapeutic heat to biological tissues and fluids using gas filled liposomes
HU218018B (hu) * 1991-09-17 2000-05-28 Sonus Pharmaceuticals Inc. Gázos ultrahang-kontrasztanyag és eljárás ultrahang kontrasztanyaghoz megfelelő gázok kiválasztására

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AU678341B2 (en) 1997-05-29
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DE69232518T2 (de) 2002-10-31
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EP0639067A1 (de) 1995-02-22
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