ATE213941T1 - Topische zubereitungen enthaltend benzimidazol- derivate und benzotriazol-derivate - Google Patents
Topische zubereitungen enthaltend benzimidazol- derivate und benzotriazol-derivateInfo
- Publication number
- ATE213941T1 ATE213941T1 AT94200665T AT94200665T ATE213941T1 AT E213941 T1 ATE213941 T1 AT E213941T1 AT 94200665 T AT94200665 T AT 94200665T AT 94200665 T AT94200665 T AT 94200665T AT E213941 T1 ATE213941 T1 AT E213941T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- preparations containing
- topical preparations
- effective amount
- containing benzimidazole
- Prior art date
Links
- 229940058303 antinematodal benzimidazole derivative Drugs 0.000 title 1
- 150000001556 benzimidazoles Chemical class 0.000 title 1
- 150000001565 benzotriazoles Chemical class 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 210000002919 epithelial cell Anatomy 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000001613 neoplastic effect Effects 0.000 abstract 1
- 230000001855 preneoplastic effect Effects 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
- 229930002330 retinoic acid Natural products 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960001727 tretinoin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/496—Triazoles or their condensed derivatives, e.g. benzotriazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/28—Antiandrogens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27715288A | 1988-11-29 | 1988-11-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE213941T1 true ATE213941T1 (de) | 2002-03-15 |
Family
ID=23059616
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89203001T ATE112681T1 (de) | 1988-11-29 | 1989-11-27 | Verwendung von benzimidazol-derivaten bei der behandlung von epithelialen erkrankungen. |
| AT94200665T ATE213941T1 (de) | 1988-11-29 | 1989-11-27 | Topische zubereitungen enthaltend benzimidazol- derivate und benzotriazol-derivate |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89203001T ATE112681T1 (de) | 1988-11-29 | 1989-11-27 | Verwendung von benzimidazol-derivaten bei der behandlung von epithelialen erkrankungen. |
Country Status (16)
| Country | Link |
|---|---|
| EP (2) | EP0609963B1 (de) |
| JP (2) | JP2752200B2 (de) |
| AT (2) | ATE112681T1 (de) |
| AU (2) | AU623454B2 (de) |
| CA (1) | CA2002859C (de) |
| CY (1) | CY1867A (de) |
| DE (2) | DE68929377T2 (de) |
| DK (1) | DK175793B1 (de) |
| ES (2) | ES2065369T3 (de) |
| HK (1) | HK114895A (de) |
| IE (1) | IE63877B1 (de) |
| IL (1) | IL92487A (de) |
| NZ (1) | NZ231405A (de) |
| PT (1) | PT92449B (de) |
| SG (1) | SG50466A1 (de) |
| ZA (1) | ZA899074B (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2002859C (en) * | 1988-11-29 | 1998-12-29 | Jean P. F. Van Wauwe | Method of treating epithelial disorders |
| PL176059B1 (pl) * | 1992-11-10 | 1999-03-31 | Janssen Pharmaceutica Nv | Sposób wytwarzania enancjomerycznie czystego 6-[(4-chlorofenylo) (1H-1,2,4-triazol-1-ilo)-metylo]-1-metylo-1H-benzotriazolu |
| US5484612A (en) * | 1993-09-22 | 1996-01-16 | The Board Of Trustees Of The Leland Stanford Junior University | Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin |
| CN1141042A (zh) * | 1994-02-18 | 1997-01-22 | 詹森药业有限公司 | 旋光对映纯的(+)-利罗唑 |
| MX9603510A (es) * | 1994-02-18 | 1997-03-29 | Janssen Pharmaceutica Nv | (-)-liarozol enantiomericamente puro. |
| EP0800391A1 (de) * | 1994-12-28 | 1997-10-15 | Janssen Pharmaceutica N.V. | Benzimidazole zur hemmung des calcitriol-metabolismus |
| TW316902B (de) * | 1994-12-28 | 1997-10-01 | Janssen Pharmaceutica Nv | |
| US5536740A (en) * | 1995-06-01 | 1996-07-16 | Elizabeth Arden Company, Division Of Conopco, Inc. | Skin care compositions containing dimethyl imidazolidinone and retinol or retinyl ester |
| AU6821196A (en) * | 1995-08-14 | 1997-03-12 | Janssen Pharmaceutica N.V. | Transdermal administration of vorozole |
| TW349948B (en) * | 1995-10-31 | 1999-01-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 2-quinolone derivatives |
| US5716627A (en) * | 1996-04-25 | 1998-02-10 | Elizabeth Arden Co., Division Of Conopco, Inc. | Skin care compositions containing fatty acid amides, azoles, and retinol or retinyl ester |
| CN1102593C (zh) | 1996-06-27 | 2003-03-05 | 詹森药业有限公司 | N－[4－(杂芳基甲基)苯基]－杂芳基胺类化合物 |
| JPH10220909A (ja) | 1996-12-03 | 1998-08-21 | Komatsu Ltd | 流体温度制御装置 |
| TW591030B (en) | 1997-03-10 | 2004-06-11 | Janssen Pharmaceutica Nv | Farnesyl transferase inhibiting 1,8-annelated quinolinone derivatives substituted with N- or C-linked imidazoles |
| DK1037880T3 (da) | 1997-12-11 | 2004-11-15 | Janssen Pharmaceutica Nv | Anilider som retinsyremimetika |
| DK1097150T3 (da) * | 1998-06-16 | 2004-07-26 | Sod Conseils Rech Applic | Imidazolylderivater |
| US6420555B1 (en) | 1998-06-16 | 2002-07-16 | Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. | Imidazolyl derivatives |
| WO2000066077A1 (en) * | 1999-04-29 | 2000-11-09 | Avon Products, Inc. | Method of improving the aesthetic appearance of epithelia |
| EP1420015A1 (de) * | 1999-06-11 | 2004-05-19 | Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. | Imidazol-Derivate |
| FR2815857B1 (fr) * | 2000-10-30 | 2003-02-14 | Oreal | Composition, notamment cosmetique, renfermant un retinoide et une silicone benzotriazole |
| US7405235B2 (en) | 2001-05-04 | 2008-07-29 | Paratek Pharmaceuticals, Inc. | Transcription factor modulating compounds and methods of use thereof |
| EP1558341A4 (de) * | 2002-11-01 | 2010-09-08 | Paratek Pharm Innc | Transkriptionsfaktor modulierendeverbindungen und ihre verwendung |
| JP2008504233A (ja) | 2004-04-23 | 2008-02-14 | パラテック ファーマシューティカルズ インコーポレイテッド | 転写因子調節化合物およびその使用法 |
| CA2785536C (en) | 2009-12-30 | 2018-02-27 | Arqule, Inc. | Substituted imidazopyridinyl-aminopyridine compounds |
| US8609688B2 (en) | 2011-06-24 | 2013-12-17 | Arqule, Inc. | Substituted imidazopyridinyl-aminopyridine compounds |
| WO2012177852A1 (en) | 2011-06-24 | 2012-12-27 | Arqule, Inc | Substituted imidazopyridinyl compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4859684A (en) * | 1986-09-15 | 1989-08-22 | Janssen Pharmaceutica N.V. | (1H-imidazol-1-ylmethyl) substituted benzimidazole derivatives and use thereof in treating androgen dependent disorders |
| NZ221729A (en) * | 1986-09-15 | 1989-07-27 | Janssen Pharmaceutica Nv | Imidazolyl methyl-substituted benzimidazole derivatives and pharmaceutical compositions |
| NZ224714A (en) * | 1987-06-01 | 1990-03-27 | Janssen Pharmaceutica Nv | Substituted benzotriazole derivatives and pharmaceutical compositions |
| CA2002859C (en) * | 1988-11-29 | 1998-12-29 | Jean P. F. Van Wauwe | Method of treating epithelial disorders |
-
1989
- 1989-11-14 CA CA002002859A patent/CA2002859C/en not_active Expired - Lifetime
- 1989-11-15 NZ NZ231405A patent/NZ231405A/xx unknown
- 1989-11-27 ES ES89203001T patent/ES2065369T3/es not_active Expired - Lifetime
- 1989-11-27 ES ES94200665T patent/ES2173902T3/es not_active Expired - Lifetime
- 1989-11-27 AT AT89203001T patent/ATE112681T1/de not_active IP Right Cessation
- 1989-11-27 DE DE68929377T patent/DE68929377T2/de not_active Expired - Lifetime
- 1989-11-27 SG SG1996002122A patent/SG50466A1/en unknown
- 1989-11-27 EP EP94200665A patent/EP0609963B1/de not_active Expired - Lifetime
- 1989-11-27 EP EP89203001A patent/EP0371559B1/de not_active Expired - Lifetime
- 1989-11-27 DE DE68918809T patent/DE68918809T2/de not_active Expired - Lifetime
- 1989-11-27 AT AT94200665T patent/ATE213941T1/de not_active IP Right Cessation
- 1989-11-28 DK DK198905995A patent/DK175793B1/da not_active IP Right Cessation
- 1989-11-28 IE IE378189A patent/IE63877B1/en not_active IP Right Cessation
- 1989-11-28 ZA ZA899074A patent/ZA899074B/xx unknown
- 1989-11-28 IL IL9248789A patent/IL92487A/en not_active IP Right Cessation
- 1989-11-28 AU AU45648/89A patent/AU623454B2/en not_active Expired
- 1989-11-29 JP JP1307792A patent/JP2752200B2/ja not_active Expired - Lifetime
- 1989-11-29 PT PT92449A patent/PT92449B/pt not_active IP Right Cessation
-
1992
- 1992-01-31 AU AU10716/92A patent/AU630579B2/en not_active Expired
-
1995
- 1995-07-13 HK HK114895A patent/HK114895A/en not_active IP Right Cessation
-
1996
- 1996-04-05 CY CY186796A patent/CY1867A/xx unknown
-
1997
- 1997-05-13 JP JP9137444A patent/JP2912596B2/ja not_active Expired - Lifetime
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |