ATE209921T1 - Verwendung von vitamin d und seinen derivaten zur herstellung eines medikamentes zum schutz vor neuronenverlust - Google Patents
Verwendung von vitamin d und seinen derivaten zur herstellung eines medikamentes zum schutz vor neuronenverlustInfo
- Publication number
- ATE209921T1 ATE209921T1 AT94923484T AT94923484T ATE209921T1 AT E209921 T1 ATE209921 T1 AT E209921T1 AT 94923484 T AT94923484 T AT 94923484T AT 94923484 T AT94923484 T AT 94923484T AT E209921 T1 ATE209921 T1 AT E209921T1
- Authority
- AT
- Austria
- Prior art keywords
- vitamin
- compound
- neuron loss
- against neuron
- protect against
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Signal Processing For Digital Recording And Reproducing (AREA)
- Moving Of Heads (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9197693A | 1993-07-15 | 1993-07-15 | |
PCT/US1994/007917 WO1995002409A2 (en) | 1993-07-15 | 1994-07-14 | Use of vitamin d and derivatives thereof for the manufacture of a medicament for protection against neuron loss |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE209921T1 true ATE209921T1 (de) | 2001-12-15 |
Family
ID=22230588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT94923484T ATE209921T1 (de) | 1993-07-15 | 1994-07-14 | Verwendung von vitamin d und seinen derivaten zur herstellung eines medikamentes zum schutz vor neuronenverlust |
Country Status (10)
Country | Link |
---|---|
US (1) | US5939407A (de) |
EP (1) | EP0710112B1 (de) |
JP (1) | JPH09507830A (de) |
AT (1) | ATE209921T1 (de) |
AU (1) | AU7333694A (de) |
CA (1) | CA2167171C (de) |
DE (1) | DE69429351T2 (de) |
ES (1) | ES2166377T3 (de) |
IL (1) | IL110309A0 (de) |
WO (1) | WO1995002409A2 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1011683A4 (de) * | 1997-05-22 | 2003-06-11 | Cephalon Inc | Vitamin d analoge und der wirkung auf neuronen |
NZ507449A (en) * | 1998-05-15 | 2003-08-29 | Univ Leland Stanford Junior | Glucocorticoid receptor antagonists for the treatment of dementia |
AU6137801A (en) * | 2000-05-09 | 2001-11-20 | Childrens Medical Center | Method and composition for the treatment of angiogenesis |
US7858602B2 (en) * | 2000-10-16 | 2010-12-28 | Rodriguez Victorio C | Therapeutic and prophylactic uses of cell specific carbonic anhydrase enzymes in treating aging disorders due to oxidative stress and as growth factors of stem cells |
US7256184B2 (en) * | 2000-10-16 | 2007-08-14 | Rodriguez Victorio C | Treatment of aging disorders in humans |
EP1330467B1 (de) * | 2000-11-03 | 2007-05-02 | Washington University | Östronderivate mit zellschützender wirkung |
AU2002228891A1 (en) * | 2000-11-17 | 2002-05-27 | Washington University | Cytoprotective estrogen derivatives |
AU2002303652B2 (en) * | 2001-05-04 | 2006-08-31 | Corcept Therapeutics, Inc. | Methods for treating delirium using glucocorticoid receptor-specific antagonists |
US20040053895A1 (en) * | 2002-09-18 | 2004-03-18 | Bone Care International, Inc. | Multi-use vessels for vitamin D formulations |
US7148211B2 (en) * | 2002-09-18 | 2006-12-12 | Genzyme Corporation | Formulation for lipophilic agents |
US20040058895A1 (en) * | 2002-09-18 | 2004-03-25 | Bone Care International, Inc. | Multi-use vessels for vitamin D formulations |
US20050192255A1 (en) * | 2003-07-30 | 2005-09-01 | Jin Tian | Use of Vitamin Ds or Vitamin D analogs to treat cardiovascular disease |
WO2005116047A2 (en) * | 2004-05-27 | 2005-12-08 | Migenix Corp. | 2-substituted 17-imino estrogen compounds for cytoprotection |
AU2006251832A1 (en) * | 2005-05-27 | 2006-11-30 | Queen's University At Kingston | Treatment of protein folding disorders |
JP2007023010A (ja) * | 2005-07-19 | 2007-02-01 | Toshiro Azegami | 閉経後のホルモンバランス調整及びパーキンソン症の予防改善目的の経口組成物 |
HUE035852T2 (en) * | 2006-04-03 | 2018-05-28 | Accera Inc | Use of ketogen compounds to treat memory decline |
EP2167098B1 (de) * | 2007-06-11 | 2018-09-05 | University Of Southern California | Allopregnanolon in einer methode zur verstärkung der neurologischen funktion (alzheimer krankheit) |
US20100204192A1 (en) | 2007-06-11 | 2010-08-12 | University Of Sourthern California | Agents, compositions and methods for enhancing neurological function |
US20110306579A1 (en) * | 2009-01-30 | 2011-12-15 | Emory University | Methods of neuroprotection using neuroprotective steroids and a vitamin d |
EP2363119A1 (de) * | 2010-03-05 | 2011-09-07 | Centre Hospitalier Universitaire d'Angers | Neue pharmazeutische Zusammensetzung, die zur Behandlung von Patienten mit neurodegenerativen oder neurovaskulären Erkrankungen geeignet ist |
FR2965178B1 (fr) * | 2010-09-29 | 2012-10-05 | Sebastien Lasnier | Composition pharmaceutique utilise dans le traitement de la maladie d'alzheimer |
ES2951664T3 (es) * | 2011-09-08 | 2023-10-24 | Sage Therapeutics Inc | Esteroides neuroactivos, composiciones y usos de los mismos |
EP3932932A1 (de) | 2013-03-13 | 2022-01-05 | Sage Therapeutics, Inc. | Neuroaktive steroide und verfahren zur verwendung davon |
US20140296190A1 (en) * | 2013-03-27 | 2014-10-02 | Dsm Ip Assets B.V. | Marketing the use of 25-hydroxyvitamin d3 to enhance cognition |
CN105208878A (zh) * | 2013-03-27 | 2015-12-30 | 帝斯曼知识产权资产管理有限公司 | 25-羟基维生素d3用于增强执行功能的用途 |
ES2536256B2 (es) | 2013-11-20 | 2016-02-01 | Universidade De Santiago De Compostela | Análogos de vitamina d con interés farmacéutico |
EP4306114A1 (de) | 2014-06-18 | 2024-01-17 | Sage Therapeutics, Inc. | Oxysterole und verfahren zu ihrer verwendung |
MA42409A (fr) | 2015-07-06 | 2018-05-16 | Sage Therapeutics Inc | Oxystérols et leurs procédés d'utilisation |
RU2021100620A (ru) | 2015-07-06 | 2021-01-29 | Сейдж Терапьютикс, Инк. | Оксистеролы и способы их применения |
MY197698A (en) | 2015-07-06 | 2023-07-06 | Sage Therapeutics Inc | Oxysterols and methods of use thereof |
LT3436022T (lt) | 2016-04-01 | 2022-06-27 | Sage Therapeutics, Inc. | Oksisteroliai ir jų panaudojimo būdai |
WO2017193046A1 (en) | 2016-05-06 | 2017-11-09 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
ES2884071T3 (es) | 2016-07-07 | 2021-12-10 | Sage Therapeutics Inc | 24-hidroxiesteroles sustituidos en 11 para el tratamiento de afecciones relacionadas con NMDA |
CN110023323A (zh) | 2016-09-30 | 2019-07-16 | 萨奇治疗股份有限公司 | C7取代的氧固醇及其作为nmda调节剂的方法 |
MA46565A (fr) | 2016-10-18 | 2019-08-28 | Sage Therapeutics Inc | Oxystérols et leurs procédés d'utilisation |
CA3041088C (en) | 2016-10-18 | 2024-05-21 | Sage Therapeutics, Inc. | Oxysterols and methods of use thereof |
US20230218581A1 (en) | 2020-04-24 | 2023-07-13 | The Johns Hopkins University | Compositions and methods comprising dendrimers and therapeutic agents |
WO2023028554A1 (en) | 2021-08-25 | 2023-03-02 | Neuraly, Inc. | Glp-1r agonists for use in a treatment of neurological impairment associated with viral infection |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS63104926A (ja) * | 1986-10-21 | 1988-05-10 | Teijin Ltd | 老年性痴呆症治療又は予防剤 |
FR2639225B1 (fr) * | 1988-11-21 | 1993-05-21 | Centre Nat Rech Scient | Compositions pharmaceutiques pour la neuroprotection contenant des arylcyclohexylamines |
US4897388A (en) * | 1988-12-20 | 1990-01-30 | Geriatric Research Institute, Inc. | Method of treating Alzheimer's disease |
US4957909A (en) * | 1989-05-04 | 1990-09-18 | American Home Products Corporation | Benzobicycloalkane derivatives as anticonvulsant neuroprotective agents |
US5089517A (en) * | 1990-08-03 | 1992-02-18 | The Board Of Trustees Of The Leland Stanford Junior University | Neuroprotection by indolactam v and derivatives thereof |
US5168103A (en) * | 1991-01-22 | 1992-12-01 | American Home Products Corporation | [[2-(amino-3,4-dioxo-1-cyclobuten-1-yl) amino]alkyl]-acid derivatives |
US5196421A (en) * | 1991-06-05 | 1993-03-23 | Eli Lilly And Company | Excitatory amino acid receptor antagonists in methods for the use thereof |
US5153196A (en) * | 1991-06-05 | 1992-10-06 | Eli Lilly And Company | Excitatory amino acid receptor antagonists and methods for the use thereof |
-
1994
- 1994-07-13 IL IL11030994A patent/IL110309A0/xx unknown
- 1994-07-14 JP JP7504720A patent/JPH09507830A/ja not_active Ceased
- 1994-07-14 AT AT94923484T patent/ATE209921T1/de not_active IP Right Cessation
- 1994-07-14 AU AU73336/94A patent/AU7333694A/en not_active Abandoned
- 1994-07-14 CA CA002167171A patent/CA2167171C/en not_active Expired - Fee Related
- 1994-07-14 EP EP94923484A patent/EP0710112B1/de not_active Expired - Lifetime
- 1994-07-14 ES ES94923484T patent/ES2166377T3/es not_active Expired - Lifetime
- 1994-07-14 WO PCT/US1994/007917 patent/WO1995002409A2/en active IP Right Grant
- 1994-07-14 DE DE69429351T patent/DE69429351T2/de not_active Expired - Fee Related
-
1997
- 1997-10-01 US US08/942,560 patent/US5939407A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ES2166377T3 (es) | 2002-04-16 |
AU7333694A (en) | 1995-02-13 |
US5939407A (en) | 1999-08-17 |
CA2167171A1 (en) | 1995-01-26 |
WO1995002409A2 (en) | 1995-01-26 |
DE69429351T2 (de) | 2002-05-23 |
EP0710112B1 (de) | 2001-12-05 |
CA2167171C (en) | 2007-04-24 |
WO1995002409A3 (en) | 1995-04-27 |
IL110309A0 (en) | 1994-10-21 |
JPH09507830A (ja) | 1997-08-12 |
DE69429351D1 (de) | 2002-01-17 |
EP0710112A1 (de) | 1996-05-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE209921T1 (de) | Verwendung von vitamin d und seinen derivaten zur herstellung eines medikamentes zum schutz vor neuronenverlust | |
BR0309623A (pt) | Agentes que regulam. inibem ou modulam a atividade e/ou a expressão do fator de crescimento de tecido conjuntivo (ctgf) como um único meio de diminuir a pressão intraocular e tratar retinopatias glaucomatosas/neuropatias ópticas | |
MD895B2 (ro) | Preparat sinergetic şi procedeu de distrugere selectivă a buruienilor | |
BRPI0407375A (pt) | Métodos para tratar dor por meio da administração de um antagonista do fator de crescimento neural e u nsaid e composições contendo os mesmos | |
MX9606404A (es) | Composiciones farmaceuticas y metodos para formular trasnduccion de señales. | |
DE3687501D1 (de) | Verwendung von gamma-linolensaeure und verwandten verbindungen zur herstellung eines arneimittels zur behandlung von komplikationen bei diabetes mellitus. | |
CA2202879A1 (en) | Calcium receptor-active compounds | |
ATE239462T1 (de) | Verwendung von kreatinanalogen zur behandlung von störungen des glukosemetabolismus | |
ATE467616T1 (de) | Verbindungen mit aktivität an der 11beta- hydroxasteroiddehydrogenase | |
DE69310634D1 (de) | Verwendung von Taxol zur Herstellung eines Arzneimittels zur Behandlung von Krebs | |
ATE206919T1 (de) | Verwendung des wirkstoffs flupirtin zur herstellung eines arzneimittels zur bekämpfung von muskelverspannungen | |
ATE286384T1 (de) | Formulierung mit verzögerter freisetzung enthaltend kollagen und glykosaminoglykan | |
NO20005161L (no) | N,N-disubstituerte amider som inhiberer bindingen av integriner til deres reseptorer | |
DE69324859D1 (de) | Verwendung von Lipid-gebundener Glykoaminoglykanen zur Behandlung der rheumatoider Arthritis | |
AU1876788A (en) | Methylene phosphonoalkylphosphinates, pharmaceutical compositions , and methods for treating abnormal calcium and phosphate metabolism | |
DE68914922D1 (de) | Verwendung von Inositoltrisphosphat zur Herstellung eines Arzneimittels gegen Knochenerkrakungen. | |
ATE98488T1 (de) | Verwendung von benzimidazolen zur herstellung eines arzneimittels mit antiischaemischen wirkungen am herzen und dessen kombinationen mit beta-blockern oder bradycardica. | |
DE69330150D1 (de) | Pharmazeutische Zusammensetzungen zur transdermalen Verabreichung von Melatonin und/oder seine Analoge | |
DE59206924D1 (de) | Ein flurbiprofen enthaltendes akutarzneimittel und seine verwendung | |
AU6408894A (en) | 2-substituted morpholine and thiomorpholine derivatives as gaba-b antagonists | |
DE69518159T2 (de) | Mittel zur vorsorge und heilung von typ i allergischen krankheiten | |
BR9811829A (pt) | Processos para fumegação do solo contendo organismos deletérios controlando ao mesmo tempo a fitotoxicidade, e, para controlar organismos deletérios no solo | |
DE69307197D1 (de) | Verwendung von 24,25-Dihydroxyvitamin-D3 zur Herstellung eines Arzneimittel zur Behandlung der Rachitis | |
DE69628430D1 (de) | Verwendung von lactoferrin zur prävention des nachoperativen astigmatismus | |
DE69121940D1 (de) | Derivate des Hydantoins zur Verwendung als hypoglycemische und/oder hypolipidemische Wirkstoffe |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |