ATE207777T1 - Dichte-gradientmedien zur trennung von zellen - Google Patents

Dichte-gradientmedien zur trennung von zellen

Info

Publication number
ATE207777T1
ATE207777T1 AT95910120T AT95910120T ATE207777T1 AT E207777 T1 ATE207777 T1 AT E207777T1 AT 95910120 T AT95910120 T AT 95910120T AT 95910120 T AT95910120 T AT 95910120T AT E207777 T1 ATE207777 T1 AT E207777T1
Authority
AT
Austria
Prior art keywords
density gradient
cells
separation
gradient media
gradient medium
Prior art date
Application number
AT95910120T
Other languages
English (en)
Inventor
Alexander M Saunders
Original Assignee
Applied Imaging Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Imaging Corp filed Critical Applied Imaging Corp
Application granted granted Critical
Publication of ATE207777T1 publication Critical patent/ATE207777T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • G01N33/491Blood by separating the blood components
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D21/00Separation of suspended solid particles from liquids by sedimentation
    • B01D21/26Separation of sediment aided by centrifugal force or centripetal force
    • B01D21/262Separation of sediment aided by centrifugal force or centripetal force by using a centrifuge
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2221/00Applications of separation devices
    • B01D2221/10Separation devices for use in medical, pharmaceutical or laboratory applications, e.g. separating amalgam from dental treatment residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Ecology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
AT95910120T 1994-01-31 1995-01-23 Dichte-gradientmedien zur trennung von zellen ATE207777T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/189,509 US5489386A (en) 1994-01-31 1994-01-31 Density gradient medium for the separation of cells
PCT/US1995/000956 WO1995020429A1 (en) 1994-01-31 1995-01-23 Density gradient medium for separating cells

Publications (1)

Publication Number Publication Date
ATE207777T1 true ATE207777T1 (de) 2001-11-15

Family

ID=22697630

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95910120T ATE207777T1 (de) 1994-01-31 1995-01-23 Dichte-gradientmedien zur trennung von zellen

Country Status (9)

Country Link
US (1) US5489386A (de)
EP (1) EP0739229B1 (de)
JP (1) JP3017291B2 (de)
AT (1) ATE207777T1 (de)
AU (1) AU680738B2 (de)
CA (1) CA2182367C (de)
DE (1) DE69523566T2 (de)
DK (1) DK0739229T3 (de)
WO (1) WO1995020429A1 (de)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI940823A0 (fi) * 1994-02-22 1994-02-22 Orion Yhtymae Oy Analysatorkyvett foer turbidimetriska och nefelometriska bestaemningar av helblodsprov
JPH11502106A (ja) * 1995-03-08 1999-02-23 バイオセパレーションズ・インコーポレーテッド 少数細胞集団を濃縮する方法
US5639669A (en) * 1995-06-07 1997-06-17 Ledley; Robert Separation of fetal cells from maternal blood
AUPN883396A0 (en) * 1996-03-21 1996-04-18 Australian Red Cross Society (Western Australian Division) Centrifugation support
US6210889B1 (en) 1998-01-28 2001-04-03 The Universite Laval Method for enrichment of fetal cells from maternal blood and use of same in determination of fetal sex and detection of chromosomal abnormalities
US6535393B2 (en) * 1998-12-04 2003-03-18 Micron Technology, Inc. Electrical device allowing for increased device densities
IT1311989B1 (it) * 1999-03-30 2002-03-22 Giammaria Sitar Procedimento per isolare cellule fetali presenti nel sangue perifericomaterno.
US7135335B2 (en) * 1999-05-28 2006-11-14 Stemcell Technologies Inc. Method for separating cells using immunorosettes
US7947236B2 (en) 1999-12-03 2011-05-24 Becton, Dickinson And Company Device for separating components of a fluid sample
JP2004525368A (ja) 2001-03-07 2004-08-19 ザ・テキサス・エイ・アンド・エム・ユニバーシテイ・システム 金属イオンキレート錯体の密度勾配溶液
US7316932B2 (en) * 2001-10-01 2008-01-08 Stemcell Technologies Inc. Method for separating cells
US7653260B2 (en) * 2004-06-17 2010-01-26 Carl Zeis MicroImaging GmbH System and method of registering field of view
US8582924B2 (en) * 2004-06-30 2013-11-12 Carl Zeiss Microimaging Gmbh Data structure of an image storage and retrieval system
US20060051265A1 (en) * 2004-09-08 2006-03-09 Health Research, Inc. Apparatus and method for sorting microstructures in a fluid medium
US7674388B2 (en) * 2005-08-10 2010-03-09 The Regents Of The University Of California Photopolymer serum separator
US9248447B2 (en) * 2005-08-10 2016-02-02 The Regents Of The University Of California Polymers for use in centrifugal separation of liquids
US7673758B2 (en) * 2005-08-10 2010-03-09 The Regents Of The University Of California Collection tubes apparatus, systems, and methods
US7971730B2 (en) * 2005-08-10 2011-07-05 The Regents Of The University Of California Collection tubes apparatus, systems and methods
US20070238088A1 (en) * 2006-03-29 2007-10-11 General Electric Company Hydrophilic functionalized colloidal silica compositions, methods of making, and uses therefor
WO2008143849A2 (en) 2007-05-14 2008-11-27 Historx, Inc. Compartment segregation by pixel characterization using image data clustering
US7907271B2 (en) * 2007-06-15 2011-03-15 Historx, Inc. Method and system for standardizing microscope instruments
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) * 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
WO2009029810A1 (en) * 2007-08-31 2009-03-05 Historx, Inc. Automatic exposure time selection for imaging tissue
ES2390171T3 (es) 2008-07-21 2012-11-07 Becton, Dickinson And Company Dispositivo de separación de fases de densidad
PL2644274T3 (pl) 2008-07-21 2015-11-30 Becton Dickinson Co Urządzenie do rozdzielania faz na podstawie gęstości
ES2754033T3 (es) 2008-07-21 2020-04-15 Becton Dickinson Co Dispositivo de separación de fase de densidad
US20100159506A1 (en) * 2008-07-25 2010-06-24 Cellscape Corporation Methods and systems for genetic analysis of fetal nucleated red blood cells
CN102165489B (zh) * 2008-09-16 2015-11-25 赫斯托克斯公司 生物标志物表达的可再现量化
CA2762131C (en) 2009-05-15 2017-03-28 Becton, Dickinson And Company Density phase separation device
EP2435108B1 (de) 2009-05-29 2016-12-07 EndoCellutions, Inc. Vorrichtung und verfahren zur absaugung und trennung von komponenten verschiedener dichte aus einem physiologischen fluid mit zellen
CA2787135C (en) 2010-01-21 2018-11-20 Biocep Ltd. Magnetic separation of rare cells
NL1037672C2 (nl) * 2010-02-01 2011-08-03 Eurotrol B V Werkwijze voor het bepalen van de betrouwbaarheid van een inrichting voor het meten van de concentratie van een stof in volledig bloed, werkwijze voor het behandelen van volledig bloed, houder en kit.
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
JP5265815B2 (ja) * 2010-08-20 2013-08-14 国立大学法人北陸先端科学技術大学院大学 血球の密度変化を利用した密度勾配遠心による有核赤血球の回収法
JP6208473B2 (ja) 2012-06-20 2017-10-04 アークレイ株式会社 血液成分を含む試料の処理方法
US9669405B2 (en) 2012-10-22 2017-06-06 The Regents Of The University Of California Sterilizable photopolymer serum separator
US9217697B2 (en) 2012-11-30 2015-12-22 Rarecyte, Inc. Apparatus, system, and method for collecting a target material
WO2014120797A1 (en) 2013-01-29 2014-08-07 Endocellutions, Inc. Cell concentration devices and methods
US9694359B2 (en) 2014-11-13 2017-07-04 Becton, Dickinson And Company Mechanical separator for a biological fluid
US11883817B2 (en) 2017-01-25 2024-01-30 Yantai Ausbio Laboratories Co., Ltd. Equipment and methods for automated sample processing for diagnostic purposes
USD898184S1 (en) 2019-01-29 2020-10-06 Handi-Craft Company Breast pump valve
KR200492521Y1 (ko) * 2019-02-11 2020-10-30 주식회사 이리농수산자재 농산물 랩핑용 결속부재
US11738288B2 (en) 2020-06-29 2023-08-29 Jacques Chammas Automated system and method to isolate specific cells from blood or bone marrow

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4049692A (en) * 1974-12-16 1977-09-20 Corning Glass Works Stabilized blood separating composition
US4101422A (en) * 1977-05-11 1978-07-18 Emery Industries, Inc. Copolyesters useful in blood separation assemblies
US4386003A (en) * 1981-09-17 1983-05-31 Sherwood Medical Industries Inc. Blood separating composition
US4416778A (en) * 1981-10-20 1983-11-22 Neocyte, Inc. Means for preparing neocyte enriched blood
US4797475A (en) * 1983-05-20 1989-01-10 The Regents Of The University Of California Method and composition for isolating white cell elements
US4818418A (en) * 1984-09-24 1989-04-04 Becton Dickinson And Company Blood partitioning method
US4751001A (en) * 1984-09-24 1988-06-14 Becton Dickinson And Company Blood partitioning apparatus
US4917801A (en) * 1984-12-04 1990-04-17 Becton Dickinson And Company Lymphocyte collection tube
US5053134A (en) * 1984-12-04 1991-10-01 Becton Dickinson And Company Lymphocyte collection tube
US5260186A (en) * 1986-03-10 1993-11-09 Boris Cercek Provision of density specific blood cells for the structuredness of the cytoplasmic matrix (SCM) test
US4927750A (en) * 1986-04-09 1990-05-22 Jeanette Simpson Cell separation process
US4835097A (en) * 1986-10-15 1989-05-30 Saunders Alexander M Method for ascertaining the history of a condition of the body from a single blood sample
EP0353587A3 (de) * 1988-07-26 1992-07-29 Nippon Paint Co., Ltd. Abdichtungsmittel für Serumabtrennung und dafür gebrauchte feine Harzteilchen
EP0500727B1 (de) * 1989-11-13 1998-01-21 Children's Medical Center Corporation Ein nichtinvasives verfahren zur trennung und zum nachweis von fetaler dna
JPH05507404A (ja) * 1990-04-23 1993-10-28 セルプロ インコーポレイティド 母体血液からの胎児細胞の富化のための方法
DE4222573C1 (de) * 1992-05-16 1993-08-12 Dorothee Dr. 4400 Muenster De Ahlert
US5275933A (en) * 1992-09-25 1994-01-04 The Board Of Trustees Of The Leland Stanford Junior University Triple gradient process for recovering nucleated fetal cells from maternal blood

Also Published As

Publication number Publication date
EP0739229A1 (de) 1996-10-30
DE69523566D1 (de) 2001-12-06
AU1833795A (en) 1995-08-15
WO1995020429A1 (en) 1995-08-03
JPH09508971A (ja) 1997-09-09
CA2182367A1 (en) 1995-08-03
DK0739229T3 (da) 2002-02-25
AU680738B2 (en) 1997-08-07
EP0739229A4 (de) 1997-12-03
JP3017291B2 (ja) 2000-03-06
US5489386A (en) 1996-02-06
EP0739229B1 (de) 2001-10-31
DE69523566T2 (de) 2002-09-05
CA2182367C (en) 2002-07-09

Similar Documents

Publication Publication Date Title
ATE207777T1 (de) Dichte-gradientmedien zur trennung von zellen
IL110364A0 (en) Enriching and identifying fetal nucleated erythrocytes in maternal blood for in situ hybridization
FI932150A (fi) Analyssystem foer glykerande blodproteiner
US4725406A (en) Apparatus and method for diagnostic analysis of biological fluids
RU99110373A (ru) Использование антител против эмбрионального гемоглобина для идентификации плодных клеток
EP0257759A3 (de) Teilchen zum Kalibrieren von Durchflusszytometriegeräten und anderen Analysevorrichtungen
DE69430365T2 (de) Isolierung fötaler erythrozyten
BR9306867A (pt) Enriquecimento e identificação de células fetais do sangue materno para a hibridização in situ
CA2469878A1 (en) Blood cell separating system
GB9518156D0 (en) Method of isolating cells
Biava et al. Fine structure of normal human juxtaglomerular cells. II. Specific and nonspecific cytoplasmic granules.
ATE186398T1 (de) Vorrichtung und verfahren zur trennung von zellen
DK0974056T3 (da) Prænatale in vitro-diagnostiske fremgangsmåder
ATE49659T1 (de) Probe zur identifizierung von hla d.
Miller et al. Comparison of acid phosphatase ACP1 variants by isoelectric focusing and conventional electrophoresis: identification of three new alleles, ACP1* N, ACP1* P and ACP1* S
ATE228026T1 (de) Methode zur erreicherung von populationen seltener zellen
Ogita et al. Differentiation of amylase isozyme in amniotic fluid with fetal age
Saunders et al. Method for separating rare cells from a population of cells
IT8783430A0 (it) Dispositivo atto ad effettuare in modo automatico il prelievo e la distribuzione standardizzata di campioni analitici in piastre contenenti terreni di coltura.
KR840002455A (ko) 비루스성 적혈구 응집 반응 시험용 조류(鳥類)고정 적혈구의 보존액
NO852702L (no) Fremgangsmaate ved lagring av blodplater, samt medium for anvendelse ved slik lagring