ATE205669T1 - Verfahren zum präparieren von gewebe für die transplantation - Google Patents

Verfahren zum präparieren von gewebe für die transplantation

Info

Publication number
ATE205669T1
ATE205669T1 AT92911147T AT92911147T ATE205669T1 AT E205669 T1 ATE205669 T1 AT E205669T1 AT 92911147 T AT92911147 T AT 92911147T AT 92911147 T AT92911147 T AT 92911147T AT E205669 T1 ATE205669 T1 AT E205669T1
Authority
AT
Austria
Prior art keywords
tissue
cells
transplantation
cryoprotectant
dilution step
Prior art date
Application number
AT92911147T
Other languages
English (en)
Inventor
John F Carpenter
Kelvin G M Brockbank
Original Assignee
Cryolife Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cryolife Inc filed Critical Cryolife Inc
Application granted granted Critical
Publication of ATE205669T1 publication Critical patent/ATE205669T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • A61L27/3687Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment characterised by the use of chemical agents in the treatment, e.g. specific enzymes, detergents, capping agents, crosslinkers, anticalcification agents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0205Chemical aspects
    • A01N1/021Preservation or perfusion media, liquids, solids or gases used in the preservation of cells, tissue, organs or bodily fluids
    • A01N1/0221Freeze-process protecting agents, i.e. substances protecting cells from effects of the physical process, e.g. cryoprotectants, osmolarity regulators like oncotic agents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/02Preservation of living parts
    • A01N1/0278Physical preservation processes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S128/00Surgery
    • Y10S128/27Cryogenic
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S623/00Prosthesis, i.e. artificial body members, parts thereof, or aids and accessories therefor
    • Y10S623/901Method of manufacturing prosthetic device

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT92911147T 1991-05-14 1992-05-14 Verfahren zum präparieren von gewebe für die transplantation ATE205669T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/699,873 US5160313A (en) 1991-05-14 1991-05-14 Process for preparing tissue for transplantation
PCT/US1992/004065 WO1992020300A1 (en) 1991-05-14 1992-05-14 Process for preparing tissue for transplant

Publications (1)

Publication Number Publication Date
ATE205669T1 true ATE205669T1 (de) 2001-10-15

Family

ID=24811272

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92911147T ATE205669T1 (de) 1991-05-14 1992-05-14 Verfahren zum präparieren von gewebe für die transplantation

Country Status (9)

Country Link
US (1) US5160313A (de)
EP (1) EP0584195B1 (de)
AT (1) ATE205669T1 (de)
AU (1) AU1891892A (de)
CA (1) CA2103025C (de)
DE (1) DE69232065T2 (de)
DK (1) DK0584195T3 (de)
ES (1) ES2164051T3 (de)
WO (1) WO1992020300A1 (de)

Families Citing this family (60)

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US8067149B2 (en) 1990-09-12 2011-11-29 Lifecell Corporation Acellular dermal matrix and method of use thereof for grafting
US5336616A (en) * 1990-09-12 1994-08-09 Lifecell Corporation Method for processing and preserving collagen-based tissues for transplantation
US5723282A (en) * 1991-07-08 1998-03-03 The American National Red Cross Method of preparing organs for vitrification
IT1256621B (it) * 1992-12-04 1995-12-12 Soluzioni crioprotettrici
US5833685A (en) * 1994-03-15 1998-11-10 Tortal; Proserfina R. Cryosurgical technique and devices
US5984858A (en) * 1995-06-07 1999-11-16 Crosscart, Inc. Meniscal xenografts
US5741248A (en) * 1995-06-07 1998-04-21 Temple University-Of The Commonwealth System Of Higher Education Fluorochemical liquid augmented cryosurgery
US6046379A (en) * 1995-06-07 2000-04-04 Stone; Kevin R. Meniscal xenografts
US5865849A (en) * 1995-06-07 1999-02-02 Crosscart, Inc. Meniscal heterografts
US6231608B1 (en) 1995-06-07 2001-05-15 Crosscart, Inc. Aldehyde and glycosidase-treated soft and bone tissue xenografts
US5913900A (en) * 1995-06-07 1999-06-22 Corsscart, Inc. Substantially native meniscal cartilage heterografts
US5702444A (en) * 1995-09-11 1997-12-30 Struthers, Mehta And Maxwell Implantable artificial endocrine pancreas
US6210440B1 (en) 1995-09-15 2001-04-03 Kevin R. Stone Anterior cruciate ligament xenografts
US6049025A (en) * 1995-09-15 2000-04-11 Stone; Kevin R. Articular cartilage xenografts
US5944755A (en) * 1995-09-15 1999-08-31 Crosscart, Inc. Articular cartilage xenografts
US5902338A (en) * 1995-09-15 1999-05-11 Crosscart, Inc. Anterior cruciate ligament heterograft
US6110206A (en) 1995-09-15 2000-08-29 Crosscart, Inc. Anterior cruciate ligament xenografts
US5782915A (en) * 1995-09-15 1998-07-21 Stone; Kevin R. Articular cartilage heterografts
US6361933B1 (en) 1996-06-14 2002-03-26 Biostore New Zealand Limited Solutions for the preservation of tissues
US6037116A (en) * 1996-06-14 2000-03-14 Biostore New Zealand, Ltd. Compositions comprising betaine, sodium citrate and sodium chloride and methods for the preservation of biological materials
US5962213A (en) * 1996-06-14 1999-10-05 Biostore New Zealand Limited Compositions and methods for the preservation of living tissues
US5879875A (en) * 1996-06-14 1999-03-09 Biostore New Zealand Compositions and methods for the preservation of living tissues
US6743575B2 (en) 1996-06-14 2004-06-01 Biostore New Zealand Ltd. Compositions and methods for the preservation of living tissues
US6114107A (en) * 1996-06-14 2000-09-05 Biostore New Zealand Limited Composition comprising raffinose, TMAO, sodium citrate and methods for the preservation of living tissues
IL128855A0 (en) * 1996-09-06 2000-01-31 Universal Preservation Technologies Inc Vitrification solutions for shelf preservation of cells tissues organs and organisms
JP2002505144A (ja) 1998-03-06 2002-02-19 クロスカート インコーポレイテッド 軟組織異種移植片
US6383732B1 (en) 1999-02-11 2002-05-07 Crosscart, Inc. Method of preparing xenograft heart valves
US6972041B1 (en) 1998-03-16 2005-12-06 Crosscart, Inc. Bone xenografts
JP2002506677A (ja) 1998-03-16 2002-03-05 クロスカート インコーポレイテッド 骨異種移植片
US6933326B1 (en) 1998-06-19 2005-08-23 Lifecell Coporation Particulate acellular tissue matrix
US6140123A (en) * 1998-10-07 2000-10-31 Cedars-Sinai Medical Center Method for conditioning and cryopreserving cells
US6267786B1 (en) 1999-02-11 2001-07-31 Crosscart, Inc. Proteoglycan-reduced soft tissue xenografts
WO2001028604A1 (en) * 1999-10-15 2001-04-26 The Brigham And Women's Hospital, Inc. Fresh, cryopreserved, or minimally fixed cardiac valvular xenografts
JP2004520828A (ja) 2000-12-27 2004-07-15 オーテック・インターナショナル,インコーポレイテッド 凍結保存された複合生体構築物の製造方法および該方法から得られる製造物
EP1392202A4 (de) * 2001-05-07 2009-10-21 Crosscart Inc Submukosale xenotransplantate
US7064187B2 (en) 2002-11-26 2006-06-20 Crosscart, Inc. Substantially non-immunogenic injectable collagen
US20080306610A1 (en) * 2007-06-07 2008-12-11 Zimmer Orthobiologics, Inc. Tissue processing for nonimmunogenic implants
US20090181807A1 (en) * 2008-01-16 2009-07-16 Jason Miguel De Los Santos Golfing aid
US8469779B1 (en) 2009-01-02 2013-06-25 Lifecell Corporation Method for debristling animal skin
EP2405742A2 (de) * 2009-03-11 2012-01-18 CryoLife, Inc. Biobelastungsreduzierende antibiotikazusammensetzung und verfahren zu ihrer verwendung
US8475827B2 (en) 2010-07-06 2013-07-02 Cryolife, Inc. Tissue implants for implantation and methods for preparing the same
US8377143B2 (en) 2010-07-06 2013-02-19 Cryolife, Inc. Tissue implants for implantation and methods for preparing the same
US8435305B2 (en) 2010-08-31 2013-05-07 Zimmer, Inc. Osteochondral graft delivery device and uses thereof
US9375513B2 (en) 2011-04-14 2016-06-28 Lifecell Corporation Regenerative materials
US9089523B2 (en) 2011-07-28 2015-07-28 Lifecell Corporation Natural tissue scaffolds as tissue fillers
AU2012355463C1 (en) 2011-12-20 2016-09-22 Lifecell Corporation Sheet tissue products
DK3501558T3 (da) 2011-12-20 2021-03-01 Lifecell Corp Flydbare vævsprodukter
EP3797801A1 (de) 2012-01-24 2021-03-31 LifeCell Corporation Längliche gewebematrizen
CA2871665A1 (en) 2012-04-24 2013-10-31 Lifecell Corporation Flowable tissue matrices
WO2014011402A1 (en) 2012-07-13 2014-01-16 Lifecell Corporation Methods for improved treatment of adipose tissue
EP2900288B1 (de) 2012-09-26 2018-01-31 Lifecell Corporation Verarbeitetes fettgewebe
EP3659633A1 (de) 2013-02-06 2020-06-03 LifeCell Corporation Verfahren für lokalisierte modifizierung von gewebeprodukten
CA2980316A1 (en) 2015-03-24 2016-09-29 Osiris Therapeutics, Inc. Compositions comprising meniscal tissues and uses thereof
AU2017274190A1 (en) 2016-06-03 2018-12-13 Lifecell Corporation Methods for localized modification of tissue products
EP3558405A1 (de) 2016-12-22 2019-10-30 LifeCell Corporation Vorrichtungen und verfahren zum kryogenen mahlen von gewebe
US11123375B2 (en) 2017-10-18 2021-09-21 Lifecell Corporation Methods of treating tissue voids following removal of implantable infusion ports using adipose tissue products
CA3075099A1 (en) 2017-10-18 2019-04-25 Lifecell Corporation Adipose tissue products and methods of production
ES2960617T3 (es) 2017-10-19 2024-03-05 Lifecell Corp Productos de matriz de tejido acelular fluida y métodos de producción
US11246994B2 (en) 2017-10-19 2022-02-15 Lifecell Corporation Methods for introduction of flowable acellular tissue matrix products into a hand
AU2020283895A1 (en) 2019-05-30 2022-01-06 Lifecell Corporation Biologic breast implant

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US3303662A (en) * 1963-03-01 1967-02-14 Union Carbide Corp Process for cell preservation
US4380997A (en) * 1981-04-07 1983-04-26 Rio Vista International, Inc. Embryo transfer method and apparatus
US4423600A (en) * 1982-12-10 1984-01-03 Mckenna Joan J Method for preservation of living organic tissue by freezing
US4890457A (en) * 1987-01-02 1990-01-02 Cryolife, Inc. Method for cryopreserving heart valves
US5145769A (en) * 1987-08-21 1992-09-08 Cryolife Inc. Method for cryopreserving blood vessels
US5145770A (en) * 1990-06-04 1992-09-08 Biosurface Technology, Inc. Cryopreservation of cultured epithelial sheets

Also Published As

Publication number Publication date
CA2103025A1 (en) 1992-11-15
EP0584195A1 (de) 1994-03-02
CA2103025C (en) 2002-10-01
AU1891892A (en) 1992-12-30
DE69232065T2 (de) 2002-01-31
EP0584195B1 (de) 2001-09-19
DE69232065D1 (de) 2001-10-25
ES2164051T3 (es) 2002-02-16
DK0584195T3 (da) 2001-11-12
US5160313A (en) 1992-11-03
WO1992020300A1 (en) 1992-11-26
EP0584195A4 (de) 1994-08-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee