ATE205506T1 - Faktor ix bindende peptide abgeleitet von faktor vii und ihre verwendung als inhibitoren der blutgerinnung - Google Patents
Faktor ix bindende peptide abgeleitet von faktor vii und ihre verwendung als inhibitoren der blutgerinnungInfo
- Publication number
- ATE205506T1 ATE205506T1 AT96917727T AT96917727T ATE205506T1 AT E205506 T1 ATE205506 T1 AT E205506T1 AT 96917727 T AT96917727 T AT 96917727T AT 96917727 T AT96917727 T AT 96917727T AT E205506 T1 ATE205506 T1 AT E205506T1
- Authority
- AT
- Austria
- Prior art keywords
- factor
- peptides
- binding
- blood clotting
- binding peptides
- Prior art date
Links
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 6
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 6
- 229960004222 factor ix Drugs 0.000 title abstract 4
- 239000003130 blood coagulation factor inhibitor Substances 0.000 title 1
- 229940012413 factor vii Drugs 0.000 title 1
- 108010076282 Factor IX Proteins 0.000 abstract 4
- 102100022641 Coagulation factor IX Human genes 0.000 abstract 3
- 230000037361 pathway Effects 0.000 abstract 3
- 108010054218 Factor VIII Proteins 0.000 abstract 2
- 102000001690 Factor VIII Human genes 0.000 abstract 2
- 230000001419 dependent effect Effects 0.000 abstract 2
- 229960000301 factor viii Drugs 0.000 abstract 2
- 108010048049 Factor IXa Proteins 0.000 abstract 1
- 108090000190 Thrombin Proteins 0.000 abstract 1
- 208000007536 Thrombosis Diseases 0.000 abstract 1
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 229940030225 antihemorrhagics Drugs 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000023555 blood coagulation Effects 0.000 abstract 1
- 230000000025 haemostatic effect Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229960004072 thrombin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
- Y10S530/83—Plasma; serum
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP95201554 | 1995-06-12 | ||
| PCT/NL1996/000236 WO1996041816A1 (en) | 1995-06-12 | 1996-06-12 | Factor ix binding peptides, derived from factor viii and their use as inhibitors of blood coagulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE205506T1 true ATE205506T1 (de) | 2001-09-15 |
Family
ID=8220373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96917727T ATE205506T1 (de) | 1995-06-12 | 1996-06-12 | Faktor ix bindende peptide abgeleitet von faktor vii und ihre verwendung als inhibitoren der blutgerinnung |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6284871B1 (de) |
| EP (1) | EP0833848B1 (de) |
| JP (1) | JPH11507664A (de) |
| AT (1) | ATE205506T1 (de) |
| AU (1) | AU713303B2 (de) |
| CA (1) | CA2221567A1 (de) |
| DE (1) | DE69615185T2 (de) |
| DK (1) | DK0833848T3 (de) |
| ES (1) | ES2162068T3 (de) |
| PT (1) | PT833848E (de) |
| WO (1) | WO1996041816A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005535588A (ja) * | 2002-04-29 | 2005-11-24 | バクスター・インターナショナル・インコーポレイテッド | 第ｖｉｉｉ因子と低密度リポタンパク質レセプター関連タンパク質との相互作用のアンタゴニスト |
| CN1703395A (zh) * | 2002-08-09 | 2005-11-30 | 特兰斯泰克制药公司 | 芳基和杂芳基化合物以及调节凝血的方法 |
| CA2531796A1 (en) * | 2003-08-08 | 2005-02-17 | Transtech Pharma, Inc. | Aryl and heteroaryl compounds, compositions, and methods of use |
| US7501538B2 (en) | 2003-08-08 | 2009-03-10 | Transtech Pharma, Inc. | Aryl and heteroaryl compounds, compositions and methods of use |
| US7208601B2 (en) * | 2003-08-08 | 2007-04-24 | Mjalli Adnan M M | Aryl and heteroaryl compounds, compositions, and methods of use |
| ATE533789T1 (de) * | 2006-12-15 | 2011-12-15 | Inst Radiation Med Amms Pla | Herstellung von mit geringen blutungen assoziiertem gerinnungshemmendem fusionsprotein und dessen verwendung |
| ES2841437T3 (es) | 2015-04-13 | 2021-07-08 | Inst Nat Sante Rech Med | Métodos y composiciones farmacéuticas para el tratamiento de enfermedades hemorrágicas |
| JP6595247B2 (ja) * | 2015-07-30 | 2019-10-23 | シスメックス株式会社 | 凝固時間の測定方法およびその装置、凝固時間測定用試薬ならびに試薬キット |
| CN115448985A (zh) * | 2021-06-08 | 2022-12-09 | 上海循曜生物科技有限公司 | 新型抗栓抗体 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA877535B (en) * | 1986-10-09 | 1988-04-11 | F. Hoffmann-La Roche & Co. Aktiengesellschaft | Factor ix-peptides |
| WO1990015615A1 (en) * | 1989-06-20 | 1990-12-27 | Scripps Clinic And Research Foundation | The phospholipid binding domain of factor viii |
| US5187155A (en) * | 1989-06-23 | 1993-02-16 | Board Of Regents, The University Of Texas System | Anticoagulant peptides |
| BE1008491A3 (fr) * | 1994-07-14 | 1996-05-07 | Croix Rouge De Belgique Depart | Sequence polypeptidique antigenique du facteur viii, fragments et/ou epitopes de celle-ci. |
| EP0910628B1 (de) * | 1996-04-24 | 2006-03-08 | The Regents of The University of Michigan | Gegen inaktivierung resistenter faktor viii |
-
1996
- 1996-06-12 DK DK96917727T patent/DK0833848T3/da active
- 1996-06-12 US US08/973,801 patent/US6284871B1/en not_active Expired - Fee Related
- 1996-06-12 JP JP9502944A patent/JPH11507664A/ja not_active Ceased
- 1996-06-12 WO PCT/NL1996/000236 patent/WO1996041816A1/en not_active Ceased
- 1996-06-12 PT PT96917727T patent/PT833848E/pt unknown
- 1996-06-12 AU AU60177/96A patent/AU713303B2/en not_active Ceased
- 1996-06-12 ES ES96917727T patent/ES2162068T3/es not_active Expired - Lifetime
- 1996-06-12 CA CA002221567A patent/CA2221567A1/en not_active Abandoned
- 1996-06-12 AT AT96917727T patent/ATE205506T1/de not_active IP Right Cessation
- 1996-06-12 DE DE69615185T patent/DE69615185T2/de not_active Expired - Fee Related
- 1996-06-12 EP EP96917727A patent/EP0833848B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996041816A1 (en) | 1996-12-27 |
| US6284871B1 (en) | 2001-09-04 |
| EP0833848A1 (de) | 1998-04-08 |
| JPH11507664A (ja) | 1999-07-06 |
| PT833848E (pt) | 2002-01-30 |
| AU713303B2 (en) | 1999-11-25 |
| DK0833848T3 (da) | 2001-11-05 |
| AU6017796A (en) | 1997-01-09 |
| DE69615185T2 (de) | 2002-06-13 |
| CA2221567A1 (en) | 1996-12-27 |
| EP0833848B1 (de) | 2001-09-12 |
| DE69615185D1 (de) | 2001-10-18 |
| ES2162068T3 (es) | 2001-12-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |