ATE204840T1 - Verfahren zur herstellung von galanthaminderivate durch asymmetrische reduktion - Google Patents

Verfahren zur herstellung von galanthaminderivate durch asymmetrische reduktion

Info

Publication number
ATE204840T1
ATE204840T1 AT96909250T AT96909250T ATE204840T1 AT E204840 T1 ATE204840 T1 AT E204840T1 AT 96909250 T AT96909250 T AT 96909250T AT 96909250 T AT96909250 T AT 96909250T AT E204840 T1 ATE204840 T1 AT E204840T1
Authority
AT
Austria
Prior art keywords
pct
galanthamin
derivatives
producing
asymmetric reduction
Prior art date
Application number
AT96909250T
Other languages
English (en)
Inventor
Ulrich Conrad Dyer
Jane Marie Paul
Raymond Mccague
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9507100.7A external-priority patent/GB9507100D0/en
Priority claimed from GBGB9601227.3A external-priority patent/GB9601227D0/en
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE204840T1 publication Critical patent/ATE204840T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96909250T 1995-04-06 1996-04-04 Verfahren zur herstellung von galanthaminderivate durch asymmetrische reduktion ATE204840T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9507100.7A GB9507100D0 (en) 1995-04-06 1995-04-06 Asymmetric reduction and products thereof
GBGB9601227.3A GB9601227D0 (en) 1996-01-22 1996-01-22 Reduction
PCT/GB1996/000843 WO1996031453A1 (en) 1995-04-06 1996-04-04 Process for preparing galanthamine derivatives by asymmetric reduction

Publications (1)

Publication Number Publication Date
ATE204840T1 true ATE204840T1 (de) 2001-09-15

Family

ID=26306827

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96909250T ATE204840T1 (de) 1995-04-06 1996-04-04 Verfahren zur herstellung von galanthaminderivate durch asymmetrische reduktion

Country Status (12)

Country Link
US (1) US6018043A (de)
EP (1) EP0819108B1 (de)
AT (1) ATE204840T1 (de)
AU (1) AU709080B2 (de)
CA (1) CA2215518C (de)
CY (1) CY2257B1 (de)
DE (1) DE69614841T2 (de)
DK (1) DK0819108T3 (de)
ES (1) ES2162042T3 (de)
PT (1) PT819108E (de)
TW (1) TW448177B (de)
WO (1) WO1996031453A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506843D0 (en) * 1995-04-03 1995-05-24 Chiroscience Ltd Oxidative process and products thereof
NZ546768A (en) * 2003-09-26 2009-07-31 Scinopharm Taiwan Ltd Resolution of a narwedine amide derivative and the synthesis of galantamine
US20050191349A1 (en) * 2003-12-31 2005-09-01 Garth Boehm Galantamine formulations
CA2552114A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Solid dosage formulations of galantamine
EP1895995A2 (de) * 2005-05-13 2008-03-12 Alza Corporation Mehrschichtige transdermale systeme zur galantamine abgabe
US20070104771A1 (en) * 2005-09-23 2007-05-10 Jay Audett Transdermal galantamine delivery system
CN100364995C (zh) * 2006-01-12 2008-01-30 兰州大学 加兰它敏制备方法
ATE540955T1 (de) 2007-06-18 2012-01-15 Aurobindo Pharma Ltd Herstellungsprozess für galantaminhydrobromid
AT507039A1 (de) * 2008-06-26 2010-01-15 Sanochemia Pharmazeutika Ag Verfahren zum herstellen von hochreinen benzazepinderivaten
CN102180886B (zh) * 2011-03-05 2015-01-21 兰州大学 加兰他敏不对称催化合成方法

Also Published As

Publication number Publication date
US6018043A (en) 2000-01-25
CY2257B1 (en) 2003-07-04
ES2162042T3 (es) 2001-12-16
WO1996031453A1 (en) 1996-10-10
EP0819108A1 (de) 1998-01-21
PT819108E (pt) 2002-02-28
AU709080B2 (en) 1999-08-19
EP0819108B1 (de) 2001-08-29
CA2215518C (en) 2006-11-28
DE69614841T2 (de) 2002-04-11
AU5281996A (en) 1996-10-23
CA2215518A1 (en) 1996-10-10
DK0819108T3 (da) 2001-11-26
TW448177B (en) 2001-08-01
DE69614841D1 (de) 2001-10-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification