ATE202373T1 - Hydrogele auf basis von dreiblockcopolymerisate, ihre herstellung und ihre verwendung - Google Patents

Hydrogele auf basis von dreiblockcopolymerisate, ihre herstellung und ihre verwendung

Info

Publication number
ATE202373T1
ATE202373T1 AT96941085T AT96941085T ATE202373T1 AT E202373 T1 ATE202373 T1 AT E202373T1 AT 96941085 T AT96941085 T AT 96941085T AT 96941085 T AT96941085 T AT 96941085T AT E202373 T1 ATE202373 T1 AT E202373T1
Authority
AT
Austria
Prior art keywords
copolymer
water
retaining
production
ratio
Prior art date
Application number
AT96941085T
Other languages
English (en)
Inventor
Michel Vert
Suming Li
Iliya Rashkov
Jose-Luis Espartero-Sanchez
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Application granted granted Critical
Publication of ATE202373T1 publication Critical patent/ATE202373T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/66—Polyesters containing oxygen in the form of ether groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S524/00—Synthetic resins or natural rubbers -- part of the class 520 series
    • Y10S524/916—Hydrogel compositions

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
AT96941085T 1995-11-29 1996-11-29 Hydrogele auf basis von dreiblockcopolymerisate, ihre herstellung und ihre verwendung ATE202373T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9514144A FR2741628B1 (fr) 1995-11-29 1995-11-29 Nouveaux hydrogels a base de copolymeres trisequences et leur application notamment a la liberation progressive de principes actifs
PCT/FR1996/001901 WO1997019973A1 (fr) 1995-11-29 1996-11-29 Nouveaux hydrogels a base de copolymeres trisequences, leur preparation et leur application

Publications (1)

Publication Number Publication Date
ATE202373T1 true ATE202373T1 (de) 2001-07-15

Family

ID=9485003

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96941085T ATE202373T1 (de) 1995-11-29 1996-11-29 Hydrogele auf basis von dreiblockcopolymerisate, ihre herstellung und ihre verwendung

Country Status (11)

Country Link
US (1) US6350812B1 (de)
EP (1) EP0863933B1 (de)
JP (2) JP4521067B2 (de)
AT (1) ATE202373T1 (de)
DE (1) DE69613481T2 (de)
DK (1) DK0863933T3 (de)
ES (1) ES2159767T3 (de)
FR (1) FR2741628B1 (de)
GR (1) GR3036586T3 (de)
PT (1) PT863933E (de)
WO (1) WO1997019973A1 (de)

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US6201072B1 (en) * 1997-10-03 2001-03-13 Macromed, Inc. Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
US6072101A (en) * 1997-11-19 2000-06-06 Amcol International Corporation Multicomponent superabsorbent gel particles
US6222091B1 (en) * 1997-11-19 2001-04-24 Basf Aktiengesellschaft Multicomponent superabsorbent gel particles
US7347850B2 (en) 1998-08-14 2008-03-25 Incept Llc Adhesion barriers applicable by minimally invasive surgery and methods of use thereof
US6632457B1 (en) 1998-08-14 2003-10-14 Incept Llc Composite hydrogel drug delivery systems
US6818018B1 (en) 1998-08-14 2004-11-16 Incept Llc In situ polymerizable hydrogels
WO2000033764A1 (en) 1998-12-04 2000-06-15 Pathak Chandrashekhar P Biocompatible crosslinked polymers
US7160931B2 (en) 2000-03-15 2007-01-09 Yu-Ling Cheng Thermally reversible implant and filler
CA2402546C (en) * 2000-03-15 2009-06-02 Yu-Ling Cheng Environment responsive gelling copolymer
US7193007B2 (en) 2000-03-15 2007-03-20 Yu-Ling Cheng Environment responsive gelling copolymer
US20040185101A1 (en) * 2001-03-27 2004-09-23 Macromed, Incorporated. Biodegradable triblock copolymers as solubilizing agents for drugs and method of use thereof
US7347988B2 (en) * 2001-11-15 2008-03-25 University Of North Texas Synthesis, uses and compositions of crystal hydrogels
BR0305034A (pt) * 2002-06-06 2004-07-20 Nippon Catalytic Chem Ind Composição para absorção de água, processo para produção da mesma, absorvente e produto absorvente
WO2003104307A1 (en) * 2002-06-10 2003-12-18 Rhodia Inc Phase-separated composition comprising two miscible solvents, and use thereof in a process for making capsules
US7649023B2 (en) * 2002-06-11 2010-01-19 Novartis Ag Biodegradable block copolymeric compositions for drug delivery
US20070054985A1 (en) * 2003-06-10 2007-03-08 Mathieu Joanicot Phase-separated composition comprising two miscible solvents, and use thereof in a process for making capsules
US20060018872A1 (en) * 2004-06-16 2006-01-26 Tew Gregory N Poly(lactic acid) copolymer hydrogels and related methods of drug delivery
US8357391B2 (en) * 2004-07-30 2013-01-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable devices comprising poly (hydroxy-alkanoates) and diacid linkages
EP1922351A1 (de) * 2005-09-07 2008-05-21 DSMIP Assets B.V. Polymere mit thioesterbindungen
FR2891746B1 (fr) * 2005-10-11 2008-01-11 Centre Nat Rech Scient Matrice poreuse biocompatible et biodegradable notamment utile pour la construction cellulaire
FR2893943B1 (fr) * 2005-11-28 2011-08-19 Centre Nat Rech Scient Procede de preparation de copolymeres par polymerisation anionique sans solvant
KR20080114721A (ko) * 2006-03-14 2008-12-31 가부시끼가이샤 제이엠에스 생체 흡수성 재료 제조용 재료, 생체 흡수성 재료 및 이들의 제조방법
JP2008069324A (ja) * 2006-09-15 2008-03-27 Mitsui Chemicals Inc 生分解性を有する水環境応答型ポリマーを含む水崩壊性組成物および水崩壊性成形体
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
JP5171146B2 (ja) * 2007-07-27 2013-03-27 学校法人 関西大学 温度応答性を有する生分解性ポリマー及びその製造方法
US8246998B2 (en) 2007-11-01 2012-08-21 Boston Scientific Scimed, Inc. Injectable biodegradable particles
US8409606B2 (en) 2009-02-12 2013-04-02 Incept, Llc Drug delivery through hydrogel plugs
US8961501B2 (en) 2010-09-17 2015-02-24 Incept, Llc Method for applying flowable hydrogels to a cornea
LT2658525T (lt) * 2010-12-29 2017-12-11 Medincell Biologiškai skaidomos vaistų tiekimo kompozicijos
US20130195946A1 (en) * 2012-01-31 2013-08-01 Aurora Stamper Insecticidal hydrogel feeding spheres
EP2866837B1 (de) * 2012-06-27 2022-12-14 Medincell S.A. Biologisch abbaubare wirkstofffreisetzung für hydrophobe zusammensetzungen
FR3027522B1 (fr) 2014-10-27 2016-12-09 I Ceram Composition poreuse chargee en principe actif
KR101694228B1 (ko) * 2014-10-29 2017-01-10 인하대학교 산학협력단 장기간 보관이 가능한 폴리디아세틸렌 기반의 바이오센서
HRP20231453T1 (hr) 2015-11-16 2024-03-01 Medincell S.A. Postupak za morseliranje i/ili usmjeravanje farmaceutski aktivnih sastojaka na sinovijalno tkivo
TWI795423B (zh) 2017-07-17 2023-03-11 法商麥迪榭爾公司 用於調節至少一種活性成份之藥物釋放動力學的可生物降解之藥物傳遞之組合物混合物
US11884765B2 (en) 2018-04-04 2024-01-30 Board Of Regents, The University Of Texas System Biodegradable elastic hydrogels for bioprinting
GB201900258D0 (en) 2019-01-08 2019-02-27 Medincell Pharmaceutical composition
EP4014963A1 (de) 2020-12-16 2022-06-22 Medincell Pharmazeutische zusammensetzung
GB202104224D0 (en) 2021-03-25 2021-05-12 Medincell Pharmaceutical composition
JP2024516264A (ja) 2021-04-30 2024-04-12 メディンセル エスアー 新規製剤
BR112024002231A2 (pt) 2021-08-05 2024-04-30 Medincell S A Composição farmacêutica

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EP0092918B1 (de) * 1982-04-22 1988-10-19 Imperial Chemical Industries Plc Mittel mit verzögerter Freigabe
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JPH0678375B2 (ja) 1985-12-09 1994-10-05 三井東圧化学株式会社 高分子多孔体の製造方法
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IL82834A (en) * 1987-06-09 1990-11-05 Yissum Res Dev Co Biodegradable polymeric materials based on polyether glycols,processes for the preparation thereof and surgical artiicles made therefrom
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Also Published As

Publication number Publication date
EP0863933A1 (de) 1998-09-16
FR2741628A1 (fr) 1997-05-30
DE69613481T2 (de) 2002-04-25
FR2741628B1 (fr) 1998-02-06
ES2159767T3 (es) 2001-10-16
GR3036586T3 (en) 2001-12-31
US6350812B1 (en) 2002-02-26
WO1997019973A1 (fr) 1997-06-05
JP4521067B2 (ja) 2010-08-11
JP2000500803A (ja) 2000-01-25
PT863933E (pt) 2001-12-28
EP0863933B1 (de) 2001-06-20
JP2008056935A (ja) 2008-03-13
DE69613481D1 (de) 2001-07-26
DK0863933T3 (da) 2001-09-24

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UEP Publication of translation of european patent specification