ATE201876T1 - Crystallines benzathin salz von cefonicid und verfahren zu seiner herstellung - Google Patents
Crystallines benzathin salz von cefonicid und verfahren zu seiner herstellungInfo
- Publication number
- ATE201876T1 ATE201876T1 AT94912302T AT94912302T ATE201876T1 AT E201876 T1 ATE201876 T1 AT E201876T1 AT 94912302 T AT94912302 T AT 94912302T AT 94912302 T AT94912302 T AT 94912302T AT E201876 T1 ATE201876 T1 AT E201876T1
- Authority
- AT
- Austria
- Prior art keywords
- cefonicid
- production
- benzathine salt
- crystalline
- crystalline benzathine
- Prior art date
Links
- DYAIAHUQIPBDIP-AXAPSJFSSA-N cefonicid Chemical compound S([C@@H]1[C@@H](C(N1C=1C(O)=O)=O)NC(=O)[C@H](O)C=2C=CC=CC=2)CC=1CSC1=NN=NN1CS(O)(=O)=O DYAIAHUQIPBDIP-AXAPSJFSSA-N 0.000 title abstract 2
- 229960004489 cefonicid Drugs 0.000 title abstract 2
- JUHORIMYRDESRB-UHFFFAOYSA-N benzathine Chemical class C=1C=CC=CC=1CNCCNCC1=CC=CC=C1 JUHORIMYRDESRB-UHFFFAOYSA-N 0.000 title 1
- 150000003839 salts Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3677893A | 1993-03-25 | 1993-03-25 | |
| PCT/US1994/003235 WO1994021649A1 (en) | 1993-03-25 | 1994-03-24 | Crystalline benzathine salt of cefonicid and its preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE201876T1 true ATE201876T1 (de) | 2001-06-15 |
Family
ID=21890602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94912302T ATE201876T1 (de) | 1993-03-25 | 1994-03-24 | Crystallines benzathin salz von cefonicid und verfahren zu seiner herstellung |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP0690865B1 (de) |
| JP (1) | JP3863915B2 (de) |
| CN (1) | CN1058496C (de) |
| AT (1) | ATE201876T1 (de) |
| AU (1) | AU684764B2 (de) |
| CA (1) | CA2158999C (de) |
| DE (1) | DE69427396T2 (de) |
| DK (1) | DK0690865T3 (de) |
| ES (1) | ES2159556T3 (de) |
| GR (1) | GR3036526T3 (de) |
| NZ (1) | NZ263721A (de) |
| PT (1) | PT690865E (de) |
| TW (1) | TW403755B (de) |
| WO (1) | WO1994021649A1 (de) |
| ZA (1) | ZA942070B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9908776D0 (en) * | 1999-04-16 | 1999-06-09 | Smithkline Beecham Plc | Formulation |
| US7585988B2 (en) * | 2003-04-25 | 2009-09-08 | Nippon Chemiphar Co., Ltd. | Salt of (2S, 3S) -3- [[(1S) -1- isobutoxymethyl-3-methylbutyl] carbamoly] oxirane-2-carboxylic acid |
| CN101497620B (zh) * | 2009-02-16 | 2011-05-04 | 浙江大学 | 一种青霉素和头孢菌素的纯化方法 |
| CN102093392B (zh) * | 2011-01-28 | 2013-04-24 | 海南灵康制药有限公司 | 一种头孢孟多酯钠的新制法 |
| CN109232610B (zh) * | 2018-09-04 | 2020-06-30 | 华北制药河北华民药业有限责任公司 | 一种头孢尼西二苄基乙二胺盐的精制方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4048311A (en) * | 1976-01-08 | 1977-09-13 | Smithkline Corporation | 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl)cephalosporins |
| US4576937A (en) * | 1984-02-29 | 1986-03-18 | Smithkline Beckman Corporation | 7-D-Mandelamido-3(1-sulfomethyltetrazol-5-yl)thiomethyl-3-cephem-4-carboxylic acid monosodium salt |
| GB8531609D0 (en) * | 1985-12-23 | 1986-02-05 | Beecham Group Plc | Compounds |
| US4737492A (en) * | 1986-12-31 | 1988-04-12 | Alcon Laboratories, Inc. | Sparingly soluble salts of cefamandole, and ophthalmic compositions containing same |
| IT1234385B (it) * | 1989-05-23 | 1992-05-18 | Sbd Synthetic And Biolog Devel | Procedimento migliorato per la produzione di una sostanza antibiotica appartenente al gruppo delle cefalosporine |
| IE921073A1 (en) * | 1991-04-04 | 1992-10-07 | Smithkline Beecham Corp | Enzymatic process for the production of cefonicid |
-
1994
- 1994-03-24 AT AT94912302T patent/ATE201876T1/de active
- 1994-03-24 JP JP52138194A patent/JP3863915B2/ja not_active Expired - Lifetime
- 1994-03-24 ZA ZA942070A patent/ZA942070B/xx unknown
- 1994-03-24 AU AU64917/94A patent/AU684764B2/en not_active Ceased
- 1994-03-24 PT PT94912302T patent/PT690865E/pt unknown
- 1994-03-24 DK DK94912302T patent/DK0690865T3/da active
- 1994-03-24 CA CA002158999A patent/CA2158999C/en not_active Expired - Fee Related
- 1994-03-24 WO PCT/US1994/003235 patent/WO1994021649A1/en not_active Ceased
- 1994-03-24 NZ NZ263721A patent/NZ263721A/en not_active IP Right Cessation
- 1994-03-24 DE DE69427396T patent/DE69427396T2/de not_active Expired - Lifetime
- 1994-03-24 ES ES94912302T patent/ES2159556T3/es not_active Expired - Lifetime
- 1994-03-24 EP EP94912302A patent/EP0690865B1/de not_active Expired - Lifetime
- 1994-04-18 TW TW083103418A patent/TW403755B/zh not_active IP Right Cessation
-
1996
- 1996-12-12 CN CN96123221A patent/CN1058496C/zh not_active Expired - Fee Related
-
2001
- 2001-09-05 GR GR20010401386T patent/GR3036526T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ZA942070B (en) | 1995-01-31 |
| DK0690865T3 (da) | 2001-09-24 |
| CN1123549A (zh) | 1996-05-29 |
| CA2158999A1 (en) | 1994-09-29 |
| PT690865E (pt) | 2001-11-30 |
| AU6491794A (en) | 1994-10-11 |
| AU684764B2 (en) | 1998-01-08 |
| TW403755B (en) | 2000-09-01 |
| ES2159556T3 (es) | 2001-10-16 |
| EP0690865B1 (de) | 2001-06-06 |
| CN1167765A (zh) | 1997-12-17 |
| CA2158999C (en) | 2005-05-03 |
| JP3863915B2 (ja) | 2006-12-27 |
| GR3036526T3 (en) | 2001-12-31 |
| NZ263721A (en) | 1996-12-20 |
| DE69427396D1 (de) | 2001-07-12 |
| DE69427396T2 (de) | 2002-05-23 |
| JPH08508258A (ja) | 1996-09-03 |
| WO1994021649A1 (en) | 1994-09-29 |
| CN1058496C (zh) | 2000-11-15 |
| EP0690865A1 (de) | 1996-01-10 |
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