ATE196804T1 - Test für thrombosegefahr - Google Patents

Test für thrombosegefahr

Info

Publication number
ATE196804T1
ATE196804T1 AT96919107T AT96919107T ATE196804T1 AT E196804 T1 ATE196804 T1 AT E196804T1 AT 96919107 T AT96919107 T AT 96919107T AT 96919107 T AT96919107 T AT 96919107T AT E196804 T1 ATE196804 T1 AT E196804T1
Authority
AT
Austria
Prior art keywords
reagent
protein
plasma
subject
sample
Prior art date
Application number
AT96919107T
Other languages
English (en)
Inventor
Paula A Campbell
Luigi Preda
Original Assignee
Instrumentation Lab Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23939946&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE196804(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Instrumentation Lab Spa filed Critical Instrumentation Lab Spa
Application granted granted Critical
Publication of ATE196804T1 publication Critical patent/ATE196804T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/4609—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from reptiles
    • G01N2333/4613—Snake venom
    • G01N2333/462—Snake venom from Agkistrodon sp., e.g. acutase, ACTE
    • G01N2333/4626—Snake venom from Agkistrodon sp., e.g. acutase, ACTE from Agkistrodon contortrix contortrix (copperhead snake); Protac (R)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96461—Protein C (3.4.21.69)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96463—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G01N2405/04—Phospholipids, i.e. phosphoglycerides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Control Of Eletrric Generators (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
AT96919107T 1995-06-09 1996-06-06 Test für thrombosegefahr ATE196804T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/488,510 US5780255A (en) 1995-06-09 1995-06-09 Protein C pathway screening test
PCT/US1996/009036 WO1996042018A1 (en) 1995-06-09 1996-06-06 Thrombosis risk test

Publications (1)

Publication Number Publication Date
ATE196804T1 true ATE196804T1 (de) 2000-10-15

Family

ID=23939946

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96919107T ATE196804T1 (de) 1995-06-09 1996-06-06 Test für thrombosegefahr

Country Status (9)

Country Link
US (1) US5780255A (de)
EP (1) EP0830608B1 (de)
JP (1) JP3248621B2 (de)
AT (1) ATE196804T1 (de)
CA (1) CA2224465A1 (de)
DE (1) DE69610558T2 (de)
DK (1) DK0830608T3 (de)
ES (1) ES2152531T3 (de)
WO (1) WO1996042018A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE168781T1 (de) * 1993-01-29 1998-08-15 Bjoern Dahlbaeck Neue antikoagulant-cofaktor aktivität
US5708591A (en) * 1995-02-14 1998-01-13 Akzo Nobel N.V. Method and apparatus for predicting the presence of congenital and acquired imbalances and therapeutic conditions
US6898532B1 (en) 1995-06-07 2005-05-24 Biomerieux, Inc. Method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
US6321164B1 (en) 1995-06-07 2001-11-20 Akzo Nobel N.V. Method and apparatus for predicting the presence of an abnormal level of one or more proteins in the clotting cascade
US6429017B1 (en) 1999-02-04 2002-08-06 Biomerieux Method for predicting the presence of haemostatic dysfunction in a patient sample
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
DE19724239A1 (de) * 1997-06-09 1998-12-10 Max Planck Gesellschaft Dysprothrombinämie
US6502040B2 (en) 1997-12-31 2002-12-31 Biomerieux, Inc. Method for presenting thrombosis and hemostasis assay data
AUPP159698A0 (en) * 1998-02-02 1998-02-26 Life Therapeutics Limited Improved blood coagulation test
DE19858278A1 (de) * 1998-12-17 2000-06-21 Dade Behring Marburg Gmbh Verfahren zum Lokalisieren von Defekten im Gerinnungssystem
AU774889B2 (en) 1999-02-04 2004-07-08 Biomerieux, Inc. A method and apparatus for predicting the presence of haemostatic dysfunction in a patient sample
EP1045250A1 (de) * 1999-04-12 2000-10-18 INSTRUMENTATION LABORATORY S.p.A. Test zur Auswertung der Funktionalität des Thrombin/Antithrombin Systemes
US20020037528A1 (en) * 1999-08-13 2002-03-28 Berg David E. Method for detecting procoagulant genetic and metabolic conditions associated with, and potentially predispositional for, activation of the coagulation response
US7179612B2 (en) 2000-06-09 2007-02-20 Biomerieux, Inc. Method for detecting a lipoprotein-acute phase protein complex and predicting an increased risk of system failure or mortality
US6432658B1 (en) 2000-09-13 2002-08-13 Affinity Biologicals, Inc. Method for measuring antithrombin activity
AU2002220275A1 (en) * 2000-12-08 2002-06-18 The Board Of Trustees Of The University Of Illinois Mutated class ii major histocompatibility proteins
US6855509B2 (en) * 2000-12-19 2005-02-15 Instrumentation Laboratory Company Protein S functional assay and kit therefor
ATE439601T1 (de) * 2000-12-19 2009-08-15 Instrumentation Lab Co Funktionelles assay für protein s
RU2722280C1 (ru) * 2019-09-27 2020-05-28 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр гематологии" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ гематологии" Минздрава России) Способ прогнозирования тромбоэмболических осложнений у женщин при носительстве мутаций гена протромбина [F2(20210)GA]

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DE2431342C3 (de) * 1973-07-27 1978-10-26 Behringwerke Ag, 3550 Marburg Verfahren zur Messung des Plasminogengehaltes durch Bestimmung der Bildung von Fibrin in einer Probe
ES431736A1 (es) * 1973-11-13 1977-05-16 Behringwerke Ag Procedimiento para la preparacion de un agente para diagnos-tico para el proposito de efectuar el control de la capaci- dad de coagulacion de la sangre.
NL7508671A (nl) * 1974-07-26 1976-01-28 Behringwerke Ag Werkwijze voor het bepalen van plastiminogeen.
DE2461969A1 (de) * 1974-12-31 1976-07-08 Behringwerke Ag Stabiles blutplasma, verfahren zu dessen herstellung und seine verwendung als vergleichsplasma bei gerinnungs- untersuchungen
DE2601372C3 (de) * 1976-01-15 1980-03-27 Behringwerke Ag, 3550 Marburg Verfahren zur Bestimmung von Antithrombin III
DE2757992A1 (de) * 1977-12-24 1979-06-28 Boehringer Mannheim Gmbh Verfahren zur prothrombin-bestimmung
JPS5856695A (ja) * 1981-09-28 1983-04-04 Nitto Boseki Co Ltd 新規なトロンビン測定用基質
CA1213198A (en) * 1982-09-29 1986-10-28 James E. Hughes Diagnostic activated partial thromboplastin reagent
DE3311287A1 (de) * 1983-03-28 1984-10-04 Behringwerke Ag, 3550 Marburg Verfahren zur fotometrischen bestimmung der aktivierten partiellen thromboplastinzeit und reagenz dazu
DE3330699A1 (de) * 1983-08-25 1985-03-07 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur gleichzeitigen bestimmung von fibrinogen und fibrinogen-spaltprodukten im plasma
DE3400434A1 (de) * 1984-01-09 1985-09-26 Behringwerke Ag, 3550 Marburg Bestimmung von fibrin mit fibrin-spezifischen antikoerpern
DE3413311A1 (de) * 1984-04-09 1985-10-17 Behringwerke Ag, 3550 Marburg Reagenz zur bestimmung der thromboplastinzeit
US4849403A (en) * 1985-05-29 1989-07-18 Pentapharm Ag Protein C activator, methods of preparation and use thereof
DE3607559A1 (de) * 1986-03-07 1987-09-10 Boehringer Mannheim Gmbh Verfahren zur photometrischen bestimmung der protein c- und/oder protein s-aktivitaet
US5200322A (en) * 1986-09-19 1993-04-06 Nippon Zoki Pharmaceutical Co., Ltd. Method for assaying protein C and measuring kit for the same
DE3736589A1 (de) * 1987-10-29 1989-05-11 Behringwerke Ag Glutaminhaltige peptide, verfahren zu deren herstellung und verwendung
DE3811647A1 (de) * 1988-04-07 1989-10-26 Behringwerke Ag Verfahren und verpackung enthaltend mittel zur kinetischen bestimmung von faktor xiii
US5206140A (en) * 1988-06-24 1993-04-27 Research Corporation Technologies, Inc. Assay for soluble crosslinked fibrin polymers
IT1230744B (it) * 1989-07-07 1991-10-29 Instrumentation Lab Spa Metodo per la determinazione della attivita' funzionale della proteina s nel plasma umano.
SE464135B (sv) * 1989-07-14 1991-03-11 Kabivitrum Ab Foerfarande foer bestaemning av funktionell aktivitet av fritt protein s eller protein c i ett plasmaprov
US5169786A (en) * 1989-12-19 1992-12-08 Ortho Diagnostic Systems, Inc. Method of determining levels of extrinsic and intrinsic clotting factors and protein c
DE4006634A1 (de) * 1990-03-03 1991-09-05 Behringwerke Ag Funktioneller test zur bestimmung der protein s-aktivitaet
AU2870992A (en) * 1991-10-04 1993-05-03 Board Of Regents Of The University Of Nebraska, The A soluble thrombomodulin-based one-stage assay for vitamin k-dependent coagulation-inhibiting proteins
DE4133946A1 (de) * 1991-10-14 1993-04-15 Behringwerke Ag Funktioneller test und reagenz zur bestimmung von fibrinogen
DE608235T1 (de) * 1991-11-13 1994-12-22 Bjoern Dahlbaeck Vefahren zur diagnose von störungen der blutgerinnung.
FR2689640B1 (fr) * 1992-04-06 1997-08-08 Bio Merieux Procede pour la determination d'une activite proteine c et/ou proteine s dans un echantillon plasmatique.
ES2131543T3 (es) * 1993-06-30 1999-08-01 Stiftung Fur Diagnostische For Medicion del tiempo de tromboplastina parcial activado (aptt) en una reaccion de una sola etapa.
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Also Published As

Publication number Publication date
MX9709961A (es) 1998-10-31
DE69610558T2 (de) 2001-05-31
JPH11504718A (ja) 1999-04-27
DK0830608T3 (da) 2000-11-20
DE69610558D1 (en) 2000-11-09
WO1996042018A1 (en) 1996-12-27
ES2152531T3 (es) 2001-02-01
US5780255A (en) 1998-07-14
EP0830608B1 (de) 2000-10-04
EP0830608A1 (de) 1998-03-25
JP3248621B2 (ja) 2002-01-21
CA2224465A1 (en) 1996-12-27

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Legal Events

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UEP Publication of translation of european patent specification