ATE192745T1 - 3-(piperid-4-yl)-1,2-benzisoxazol- und 3- (piperazin-4-yl)-1,2-benzisoxazol-derivate als antipsychotika - Google Patents

3-(piperid-4-yl)-1,2-benzisoxazol- und 3- (piperazin-4-yl)-1,2-benzisoxazol-derivate als antipsychotika

Info

Publication number
ATE192745T1
ATE192745T1 AT97401243T AT97401243T ATE192745T1 AT E192745 T1 ATE192745 T1 AT E192745T1 AT 97401243 T AT97401243 T AT 97401243T AT 97401243 T AT97401243 T AT 97401243T AT E192745 T1 ATE192745 T1 AT E192745T1
Authority
AT
Austria
Prior art keywords
benzisoxazole
piperide
antipsychotics
piperazine
derivatives
Prior art date
Application number
AT97401243T
Other languages
English (en)
Inventor
Jean-Louis Peglion
Mark Millan
Mauricette Brocco
Valerie Audinot
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Application granted granted Critical
Publication of ATE192745T1 publication Critical patent/ATE192745T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT97401243T 1996-06-04 1997-06-04 3-(piperid-4-yl)-1,2-benzisoxazol- und 3- (piperazin-4-yl)-1,2-benzisoxazol-derivate als antipsychotika ATE192745T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9606866A FR2749304B1 (fr) 1996-06-04 1996-06-04 Nouveaux derives du 3-(piperid-4-yl)1,2-benzisoxazole et du 3-(piperazin-4-yl)1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ATE192745T1 true ATE192745T1 (de) 2000-05-15

Family

ID=9492694

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97401243T ATE192745T1 (de) 1996-06-04 1997-06-04 3-(piperid-4-yl)-1,2-benzisoxazol- und 3- (piperazin-4-yl)-1,2-benzisoxazol-derivate als antipsychotika

Country Status (19)

Country Link
US (1) US5780474A (de)
EP (1) EP0811622B1 (de)
JP (1) JPH1059967A (de)
CN (1) CN1073565C (de)
AT (1) ATE192745T1 (de)
AU (1) AU715266B2 (de)
BR (1) BR9703447A (de)
CA (1) CA2207835C (de)
DE (1) DE69701923T2 (de)
DK (1) DK0811622T3 (de)
ES (1) ES2148916T3 (de)
FR (1) FR2749304B1 (de)
GR (1) GR3033996T3 (de)
HU (1) HUP9700992A3 (de)
NO (1) NO308360B1 (de)
NZ (1) NZ314992A (de)
PL (1) PL187005B1 (de)
PT (1) PT811622E (de)
ZA (1) ZA974919B (de)

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US9286294B2 (en) 1992-12-09 2016-03-15 Comcast Ip Holdings I, Llc Video and digital multimedia aggregator content suggestion engine
US7168084B1 (en) 1992-12-09 2007-01-23 Sedna Patent Services, Llc Method and apparatus for targeting virtual objects
US6263443B1 (en) * 1997-10-11 2001-07-17 Agere Systems Guardian Corp. Simplified data link protocol processor
DE69936572T2 (de) * 1998-02-09 2008-06-19 Duphar International Research B.V. Benzisoxazolderivate mit d4-antagonistischer wirkung
US9924234B2 (en) 1998-07-23 2018-03-20 Comcast Ip Holdings I, Llc Data structure and methods for providing an interactive program
KR100655248B1 (ko) * 1998-07-23 2006-12-08 세드나 페이턴트 서비시즈, 엘엘씨 대화형 사용자 인터페이스
US6754905B2 (en) 1998-07-23 2004-06-22 Diva Systems Corporation Data structure and methods for providing an interactive program guide
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
US6754271B1 (en) 1999-04-15 2004-06-22 Diva Systems Corporation Temporal slice persistence method and apparatus for delivery of interactive program guide
US6904610B1 (en) 1999-04-15 2005-06-07 Sedna Patent Services, Llc Server-centric customized interactive program guide in an interactive television environment
US7096487B1 (en) 1999-10-27 2006-08-22 Sedna Patent Services, Llc Apparatus and method for combining realtime and non-realtime encoded content
US7091199B1 (en) 1999-09-14 2006-08-15 Aventis Pharmaceuticals Inc. Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists
US7125903B1 (en) 1999-09-14 2006-10-24 Aventis Pharmaceuticals Inc. Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists
PT1216244E (pt) * 1999-09-14 2003-12-31 Aventis Pharma Inc Derivados de benzisoxazolil- piridoisoxazolil- e benztienil-fenoxi uteis como antagonistas d4
US7253165B2 (en) * 1999-09-14 2007-08-07 Aventis Pharmaceuticals Inc. Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists
EP1226713B1 (de) 1999-10-27 2007-04-11 Sedna Patent Services, LLC Vielfache videoströme unter verwendung von slice-basierter kodierung
FR2803298A1 (fr) * 1999-12-30 2001-07-06 Adir Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
WO2002026708A1 (fr) * 2000-09-27 2002-04-04 Toray Industries, Inc. Composes conenant de l'azote et inhibiteurs de ccr3 contenant ces composes en tant que principe actif
US7908628B2 (en) 2001-08-03 2011-03-15 Comcast Ip Holdings I, Llc Video and digital multimedia aggregator content coding and formatting
US7793326B2 (en) 2001-08-03 2010-09-07 Comcast Ip Holdings I, Llc Video and digital multimedia aggregator
US7884096B2 (en) * 2003-12-02 2011-02-08 Pharmaneuroboost N.V. Method of treating mental disorders using of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
US7855195B2 (en) * 2003-12-02 2010-12-21 Pharmaneuroboost N.V. Method of treating mental disorders using D4 and 5-HT2A antagonists, inverse agonists or partial agonists
EP1547650A1 (de) * 2003-12-02 2005-06-29 B & B Beheer NV Verwendung von D4 und 5-HT2A Antagonisten, inverse Agonisten order partielle Agonisten
CA2547639A1 (en) * 2003-12-02 2005-06-16 B&B Beheer Nv Use of d4 and 5-ht2a antagonists, inverse agonists or partial agonists
US20050119249A1 (en) * 2003-12-02 2005-06-02 Erik Buntinx Method of treating neurodegenerative diseases using D4 and 5-HT2A antagonists, inverse agonists or partial agonists
US20050203130A1 (en) * 2003-12-02 2005-09-15 Erik Buntinx Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
JP4970290B2 (ja) * 2005-02-25 2012-07-04 ファイザー株式会社 ベンズイソキサゾール誘導体
CN102164927A (zh) * 2008-09-23 2011-08-24 弗·哈夫曼-拉罗切有限公司 用作多巴胺d3受体调节剂的异唑并[4,5]吡啶-3-基-哌嗪衍生物
AU2009296045B2 (en) * 2008-09-23 2013-07-04 F. Hoffmann-La Roche Ag Benzo[d]isoxazol-3-yl-piperazin derivatives useful as modulators of dopamine D3 receptors
US9154813B2 (en) 2011-06-09 2015-10-06 Comcast Cable Communications, Llc Multiple video content in a composite video stream

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754641A (fr) * 1969-08-11 1971-02-10 Geigy Ag J R Derives de l'imidazolidinone et medicaments contenant de tels derives
US4352811A (en) * 1981-11-12 1982-10-05 Hoechst-Roussel Pharmaceuticals Inc. 3-(1-Substituted-4-piperidyl)-1,2-benzisoxazoles
US4458076A (en) * 1983-05-31 1984-07-03 Hoechst-Roussel Pharmaceuticals 3-(4-Piperidinyl)-1,2-benzisothiazoles
CA1335289C (en) * 1987-10-26 1995-04-18 Fujio Antoku Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
CN1050604C (zh) * 1993-02-04 2000-03-22 明治制果株式会社 具有抗精神病作用的化合物

Also Published As

Publication number Publication date
NO972510L (no) 1997-12-05
EP0811622A1 (de) 1997-12-10
AU2464997A (en) 1997-12-11
DE69701923T2 (de) 2000-12-14
PL187005B1 (pl) 2004-04-30
JPH1059967A (ja) 1998-03-03
ES2148916T3 (es) 2000-10-16
PL320325A1 (en) 1997-12-08
BR9703447A (pt) 1998-11-10
FR2749304B1 (fr) 1998-06-26
GR3033996T3 (en) 2000-11-30
CA2207835C (fr) 2001-10-02
CN1073565C (zh) 2001-10-24
NO972510D0 (no) 1997-06-02
CA2207835A1 (fr) 1997-12-04
PT811622E (pt) 2000-08-31
HUP9700992A2 (hu) 1998-12-28
HU9700992D0 (en) 1997-07-28
NZ314992A (en) 1999-05-28
ZA974919B (en) 1997-12-30
DK0811622T3 (da) 2000-09-11
NO308360B1 (no) 2000-09-04
US5780474A (en) 1998-07-14
FR2749304A1 (fr) 1997-12-05
DE69701923D1 (de) 2000-06-15
CN1171401A (zh) 1998-01-28
EP0811622B1 (de) 2000-05-10
HUP9700992A3 (en) 1999-03-29
AU715266B2 (en) 2000-01-20

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee