GR3033996T3 - 3-(Piperi-4-yl) 1,2-benzisoxazole and 3-(piperazin-4-yl) 1,2-benzisoxazole derivatives, processes for their preparation and pharmaceutical compositions containing them - Google Patents

3-(Piperi-4-yl) 1,2-benzisoxazole and 3-(piperazin-4-yl) 1,2-benzisoxazole derivatives, processes for their preparation and pharmaceutical compositions containing them

Info

Publication number
GR3033996T3
GR3033996T3 GR20000401682T GR20000401682T GR3033996T3 GR 3033996 T3 GR3033996 T3 GR 3033996T3 GR 20000401682 T GR20000401682 T GR 20000401682T GR 20000401682 T GR20000401682 T GR 20000401682T GR 3033996 T3 GR3033996 T3 GR 3033996T3
Authority
GR
Greece
Prior art keywords
benzisoxazole
piperi
piperazin
processes
preparation
Prior art date
Application number
GR20000401682T
Other languages
English (en)
Inventor
Jean-Louis Peglion
Mark Millan
Mauricette Brocco
Valerie Audinot
Original Assignee
Adir
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adir filed Critical Adir
Publication of GR3033996T3 publication Critical patent/GR3033996T3/el

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
GR20000401682T 1996-06-04 2000-07-21 3-(Piperi-4-yl) 1,2-benzisoxazole and 3-(piperazin-4-yl) 1,2-benzisoxazole derivatives, processes for their preparation and pharmaceutical compositions containing them GR3033996T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9606866A FR2749304B1 (fr) 1996-06-04 1996-06-04 Nouveaux derives du 3-(piperid-4-yl)1,2-benzisoxazole et du 3-(piperazin-4-yl)1,2-benzisoxazole, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
GR3033996T3 true GR3033996T3 (en) 2000-11-30

Family

ID=9492694

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000401682T GR3033996T3 (en) 1996-06-04 2000-07-21 3-(Piperi-4-yl) 1,2-benzisoxazole and 3-(piperazin-4-yl) 1,2-benzisoxazole derivatives, processes for their preparation and pharmaceutical compositions containing them

Country Status (19)

Country Link
US (1) US5780474A (el)
EP (1) EP0811622B1 (el)
JP (1) JPH1059967A (el)
CN (1) CN1073565C (el)
AT (1) ATE192745T1 (el)
AU (1) AU715266B2 (el)
BR (1) BR9703447A (el)
CA (1) CA2207835C (el)
DE (1) DE69701923T2 (el)
DK (1) DK0811622T3 (el)
ES (1) ES2148916T3 (el)
FR (1) FR2749304B1 (el)
GR (1) GR3033996T3 (el)
HU (1) HUP9700992A3 (el)
NO (1) NO308360B1 (el)
NZ (1) NZ314992A (el)
PL (1) PL187005B1 (el)
PT (1) PT811622E (el)
ZA (1) ZA974919B (el)

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US7168084B1 (en) 1992-12-09 2007-01-23 Sedna Patent Services, Llc Method and apparatus for targeting virtual objects
US9286294B2 (en) 1992-12-09 2016-03-15 Comcast Ip Holdings I, Llc Video and digital multimedia aggregator content suggestion engine
US6263443B1 (en) * 1997-10-11 2001-07-17 Agere Systems Guardian Corp. Simplified data link protocol processor
CA2320120C (en) * 1998-02-09 2009-08-11 Duphar International Research Bv Benzisoxazole derivatives having d4-antagonistic activity
US6754905B2 (en) 1998-07-23 2004-06-22 Diva Systems Corporation Data structure and methods for providing an interactive program guide
US9924234B2 (en) 1998-07-23 2018-03-20 Comcast Ip Holdings I, Llc Data structure and methods for providing an interactive program
WO2000005891A1 (en) * 1998-07-23 2000-02-03 Diva Systems Corporation Interactive user interface
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
US6754271B1 (en) 1999-04-15 2004-06-22 Diva Systems Corporation Temporal slice persistence method and apparatus for delivery of interactive program guide
US6904610B1 (en) 1999-04-15 2005-06-07 Sedna Patent Services, Llc Server-centric customized interactive program guide in an interactive television environment
US7096487B1 (en) 1999-10-27 2006-08-22 Sedna Patent Services, Llc Apparatus and method for combining realtime and non-realtime encoded content
US7091199B1 (en) 1999-09-14 2006-08-15 Aventis Pharmaceuticals Inc. Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists
US7253165B2 (en) * 1999-09-14 2007-08-07 Aventis Pharmaceuticals Inc. Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists
US7125903B1 (en) 1999-09-14 2006-10-24 Aventis Pharmaceuticals Inc. Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists
MXPA02002694A (es) * 1999-09-14 2002-07-30 Aventis Pharm Prod Inc Derivados de benzisoxazolil-, piridoisoxazolil-y benzotienil-fenoxi utiles como antagonistas de d4.
WO2001031914A1 (en) 1999-10-27 2001-05-03 Diva Systems Corporation Picture-in-picture and multiple video streams using slice-based encoding
FR2803298A1 (fr) * 1999-12-30 2001-07-06 Adir Nouvelles urees lineaires ou cycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
AU2001292276A1 (en) * 2000-09-27 2002-04-08 Toray Industries, Inc. Nitrogen-containing compounds and ccr3 inhibitors containing the same as the active ingredient
US7908628B2 (en) 2001-08-03 2011-03-15 Comcast Ip Holdings I, Llc Video and digital multimedia aggregator content coding and formatting
US7793326B2 (en) 2001-08-03 2010-09-07 Comcast Ip Holdings I, Llc Video and digital multimedia aggregator
US20050119249A1 (en) * 2003-12-02 2005-06-02 Erik Buntinx Method of treating neurodegenerative diseases using D4 and 5-HT2A antagonists, inverse agonists or partial agonists
US7855195B2 (en) * 2003-12-02 2010-12-21 Pharmaneuroboost N.V. Method of treating mental disorders using D4 and 5-HT2A antagonists, inverse agonists or partial agonists
US7884096B2 (en) * 2003-12-02 2011-02-08 Pharmaneuroboost N.V. Method of treating mental disorders using of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
WO2005053796A1 (en) * 2003-12-02 2005-06-16 B & B Beheer Nv Use of d4 and 5-ht2a antagonists, inverse agonists or partial agonists
EP1547650A1 (en) * 2003-12-02 2005-06-29 B & B Beheer NV Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
US20050203130A1 (en) * 2003-12-02 2005-09-15 Erik Buntinx Use of D4 and 5-HT2A antagonists, inverse agonists or partial agonists
JP4970290B2 (ja) * 2005-02-25 2012-07-04 ファイザー株式会社 ベンズイソキサゾール誘導体
BRPI0919342A2 (pt) * 2008-09-23 2015-12-29 Hoffmann La Roche derivados do isoxazol [4,5] piridin-3-il-piperazina, seu processo de preparação, seu medicamento e seu uso
AU2009296045B2 (en) * 2008-09-23 2013-07-04 F. Hoffmann-La Roche Ag Benzo[d]isoxazol-3-yl-piperazin derivatives useful as modulators of dopamine D3 receptors
US9154813B2 (en) 2011-06-09 2015-10-06 Comcast Cable Communications, Llc Multiple video content in a composite video stream

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE754641A (fr) * 1969-08-11 1971-02-10 Geigy Ag J R Derives de l'imidazolidinone et medicaments contenant de tels derives
US4352811A (en) * 1981-11-12 1982-10-05 Hoechst-Roussel Pharmaceuticals Inc. 3-(1-Substituted-4-piperidyl)-1,2-benzisoxazoles
US4458076A (en) * 1983-05-31 1984-07-03 Hoechst-Roussel Pharmaceuticals 3-(4-Piperidinyl)-1,2-benzisothiazoles
CA1335289C (en) * 1987-10-26 1995-04-18 Fujio Antoku Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use
US5776963A (en) * 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
KR0179063B1 (ko) * 1993-02-04 1999-03-20 사사이 아키라 항정신병 작용을 갖는 화합물

Also Published As

Publication number Publication date
NO308360B1 (no) 2000-09-04
CN1171401A (zh) 1998-01-28
DK0811622T3 (da) 2000-09-11
US5780474A (en) 1998-07-14
EP0811622A1 (fr) 1997-12-10
CA2207835C (fr) 2001-10-02
NO972510L (no) 1997-12-05
PL320325A1 (en) 1997-12-08
ZA974919B (en) 1997-12-30
FR2749304A1 (fr) 1997-12-05
HUP9700992A3 (en) 1999-03-29
NO972510D0 (no) 1997-06-02
ES2148916T3 (es) 2000-10-16
PT811622E (pt) 2000-08-31
DE69701923D1 (de) 2000-06-15
ATE192745T1 (de) 2000-05-15
JPH1059967A (ja) 1998-03-03
NZ314992A (en) 1999-05-28
DE69701923T2 (de) 2000-12-14
BR9703447A (pt) 1998-11-10
EP0811622B1 (fr) 2000-05-10
PL187005B1 (pl) 2004-04-30
CN1073565C (zh) 2001-10-24
CA2207835A1 (fr) 1997-12-04
AU715266B2 (en) 2000-01-20
HU9700992D0 (en) 1997-07-28
HUP9700992A2 (hu) 1998-12-28
FR2749304B1 (fr) 1998-06-26
AU2464997A (en) 1997-12-11

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