ATE191561T1 - Verfahren und materialien zur bestimmung der teilchenzahl in einem durchflusszytometer - Google Patents

Verfahren und materialien zur bestimmung der teilchenzahl in einem durchflusszytometer

Info

Publication number
ATE191561T1
ATE191561T1 AT93905022T AT93905022T ATE191561T1 AT E191561 T1 ATE191561 T1 AT E191561T1 AT 93905022 T AT93905022 T AT 93905022T AT 93905022 T AT93905022 T AT 93905022T AT E191561 T1 ATE191561 T1 AT E191561T1
Authority
AT
Austria
Prior art keywords
particles
specimen
suspension
cell
cells
Prior art date
Application number
AT93905022T
Other languages
English (en)
Inventor
Mark L Shenkin
Ronald M Hamelik
James C S Wood
Original Assignee
Coulter Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Corp filed Critical Coulter Corp
Application granted granted Critical
Publication of ATE191561T1 publication Critical patent/ATE191561T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/528—Atypical element structures, e.g. gloves, rods, tampons, toilet paper
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/0038—Devices for taking faeces samples; Faecal examination devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N2001/002—Devices for supplying or distributing samples to an analysing apparatus
    • G01N2001/005—Packages for mailing or similar transport of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AT93905022T 1992-02-14 1993-02-11 Verfahren und materialien zur bestimmung der teilchenzahl in einem durchflusszytometer ATE191561T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/836,638 US5451525A (en) 1992-02-14 1992-02-14 Method and materials for determining particle count in a flow cytometer
PCT/US1993/001232 WO1993016385A1 (en) 1992-02-14 1993-02-11 Method and materials for determining particle count in a flow cytometer

Publications (1)

Publication Number Publication Date
ATE191561T1 true ATE191561T1 (de) 2000-04-15

Family

ID=25272392

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93905022T ATE191561T1 (de) 1992-02-14 1993-02-11 Verfahren und materialien zur bestimmung der teilchenzahl in einem durchflusszytometer

Country Status (12)

Country Link
US (1) US5451525A (de)
EP (1) EP0627080B1 (de)
JP (1) JP3328690B2 (de)
KR (1) KR950700542A (de)
AT (1) ATE191561T1 (de)
AU (1) AU667344B2 (de)
BR (1) BR9305886A (de)
CA (1) CA2129535A1 (de)
DE (1) DE69328296T2 (de)
FI (1) FI943732A (de)
NO (1) NO942989L (de)
WO (1) WO1993016385A1 (de)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5691204A (en) * 1995-04-21 1997-11-25 Abbott Laboratories Compositions and methods for the rapid analysis of reticulocytes
US5882933A (en) * 1995-06-08 1999-03-16 Coulter International Corp. Method for determination of leukocytes and hemoglobin concentration in blood
US5942443A (en) 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
BR9710836A (pt) * 1996-04-25 2000-10-24 Spectrametrix Inc Ensaio de analitos usando marcas em partìculas
US7666308B2 (en) * 1996-06-07 2010-02-23 Veridex, Llc. Magnetic separation apparatus and methods
US6660159B1 (en) 1996-06-07 2003-12-09 Immunivest Corporation Magnetic separation apparatus and methods
US6136182A (en) * 1996-06-07 2000-10-24 Immunivest Corporation Magnetic devices and sample chambers for examination and manipulation of cells
US6890426B2 (en) * 1996-06-07 2005-05-10 Immunivest Corporation Magnetic separation apparatus and methods
US6790366B2 (en) * 1996-06-07 2004-09-14 Immunivest Corporation Magnetic separation apparatus and methods
JP3996644B2 (ja) * 1996-06-07 2007-10-24 イムニベスト・コーポレイション 外部及び内部勾配を有する磁気分離
NZ333346A (en) 1996-06-28 2000-03-27 Caliper Techn Corp High-throughput screening assay systems in microscale fluidic devices
US20060000722A1 (en) * 1996-06-28 2006-01-05 Caliper Life Sciences, Inc. High throughput screening assay systems in microscale fluidic devices
JP4209471B2 (ja) 1997-02-20 2009-01-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア プラズモン共鳴粒子、方法、および装置
US6344272B1 (en) 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
US6852252B2 (en) 1997-03-12 2005-02-08 William Marsh Rice University Use of metalnanoshells to impede the photo-oxidation of conjugated polymer
US5976994A (en) * 1997-06-13 1999-11-02 Regents Of The University Of Michigan Method and system for locally annealing a microstructure formed on a substrate and device formed thereby
US6699724B1 (en) * 1998-03-11 2004-03-02 Wm. Marsh Rice University Metal nanoshells for biosensing applications
US6428811B1 (en) 1998-03-11 2002-08-06 Wm. Marsh Rice University Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery
ES2568624T3 (es) 1999-03-05 2016-05-03 Viking Genetics F.M.B.A. Determinación de la concentración y de la viabilidad del esperma para inseminación artificial
JP3817091B2 (ja) * 1999-07-02 2006-08-30 テルモ株式会社 細胞数測定装置
JP4606543B2 (ja) * 2000-04-13 2011-01-05 パナソニック株式会社 光学特性計測装置における被検溶液量確認方法および計測系制御方法
US6784981B1 (en) * 2000-06-02 2004-08-31 Idexx Laboratories, Inc. Flow cytometry-based hematology system
US7361472B2 (en) 2001-02-23 2008-04-22 Invitrogen Corporation Methods for providing extended dynamic range in analyte assays
US7299135B2 (en) * 2005-11-10 2007-11-20 Idexx Laboratories, Inc. Methods for identifying discrete populations (e.g., clusters) of data within a flow cytometer multi-dimensional data set
WO2010135627A1 (en) 2009-05-21 2010-11-25 Intellicyt System and method for separating samples in a continuous flow
US20110129864A1 (en) * 2009-12-02 2011-06-02 Idexx Laboratories, Inc. Method for analyzing lymph node aspirate using multi-angle light scatter flow cytometer
CN103443625B (zh) * 2010-10-21 2017-12-05 耐克思乐生物科学有限责任公司 成像细胞仪的内部聚焦参考珠
WO2014169231A1 (en) 2013-04-12 2014-10-16 Norton Pierce O Automated set-up for cell sorting
US9867598B2 (en) * 2013-10-10 2018-01-16 Eiken Kagaku Kabushiki Kaisha Feces sampling container
CN115901581A (zh) 2018-03-30 2023-04-04 Idexx实验室公司 流式细胞仪的激光光学组件
CN115917292B (zh) 2020-06-17 2023-08-25 Idexx实验室公司 流式细胞仪及其激光光学组件
CN115436237B (zh) * 2022-09-22 2023-08-01 东莞理工学院 一种颗粒群尺寸分布确定方法、系统、设备及存储介质

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331862A (en) * 1979-02-23 1982-05-25 Ryan Wayne L Method for calibrating a particle counting machine and a calibration standard therefor
US4499052A (en) * 1982-08-30 1985-02-12 Becton, Dickinson And Company Apparatus for distinguishing multiple subpopulations of cells
US4751179A (en) * 1984-05-31 1988-06-14 Coulter Electronics, Inc. Method and reagents for differential determination of four populations of leukocytes in blood
US4661913A (en) * 1984-09-11 1987-04-28 Becton, Dickinson And Company Apparatus and method for the detection and classification of articles using flow cytometry techniques
US5073498A (en) * 1984-12-24 1991-12-17 Caribbean Microparticles Corporation Fluorescent alignment microbeads with broad excitation and emission spectra and its use
US4989978A (en) * 1986-04-04 1991-02-05 Technicon Instruments Corporation Method and apparatus for determining the count per unit volume of particles
US4704891A (en) * 1986-08-29 1987-11-10 Becton, Dickinson And Company Method and materials for calibrating flow cytometers and other analysis instruments
US4888290A (en) * 1987-11-06 1989-12-19 Coulter Corporation Monoclonal antibody specific to HIV antigens
IE76732B1 (en) * 1990-08-07 1997-11-05 Becton Dickinson Co One step test for absolute counts

Also Published As

Publication number Publication date
BR9305886A (pt) 1997-08-19
FI943732A0 (fi) 1994-08-12
EP0627080A1 (de) 1994-12-07
NO942989L (no) 1994-10-11
AU3617093A (en) 1993-09-03
FI943732A (fi) 1994-10-12
DE69328296T2 (de) 2000-12-21
CA2129535A1 (en) 1993-08-15
US5451525A (en) 1995-09-19
JPH07503795A (ja) 1995-04-20
AU667344B2 (en) 1996-03-21
NO942989D0 (no) 1994-08-12
KR950700542A (ko) 1995-01-16
DE69328296D1 (de) 2000-05-11
JP3328690B2 (ja) 2002-09-30
WO1993016385A1 (en) 1993-08-19
EP0627080A4 (en) 1996-11-20
EP0627080B1 (de) 2000-04-05

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