ATE191561T1 - Verfahren und materialien zur bestimmung der teilchenzahl in einem durchflusszytometer - Google Patents

Verfahren und materialien zur bestimmung der teilchenzahl in einem durchflusszytometer

Info

Publication number
ATE191561T1
ATE191561T1 AT93905022T AT93905022T ATE191561T1 AT E191561 T1 ATE191561 T1 AT E191561T1 AT 93905022 T AT93905022 T AT 93905022T AT 93905022 T AT93905022 T AT 93905022T AT E191561 T1 ATE191561 T1 AT E191561T1
Authority
AT
Austria
Prior art keywords
particles
specimen
suspension
cell
cells
Prior art date
Application number
AT93905022T
Other languages
English (en)
Inventor
Mark L Shenkin
Ronald M Hamelik
James C S Wood
Original Assignee
Coulter Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coulter Corp filed Critical Coulter Corp
Application granted granted Critical
Publication of ATE191561T1 publication Critical patent/ATE191561T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • G01N33/528—Atypical element structures, e.g. gloves, rods, tampons, toilet paper
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0038—Devices for taking faeces samples; Faecal examination devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N2001/002—Devices for supplying or distributing samples to an analysing apparatus
    • G01N2001/005—Packages for mailing or similar transport of samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/4077—Concentrating samples by other techniques involving separation of suspended solids
    • G01N2001/4088—Concentrating samples by other techniques involving separation of suspended solids filtration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1477—Multiparameters
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1486—Counting the particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
AT93905022T 1992-02-14 1993-02-11 Verfahren und materialien zur bestimmung der teilchenzahl in einem durchflusszytometer ATE191561T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/836,638 US5451525A (en) 1992-02-14 1992-02-14 Method and materials for determining particle count in a flow cytometer
PCT/US1993/001232 WO1993016385A1 (en) 1992-02-14 1993-02-11 Method and materials for determining particle count in a flow cytometer

Publications (1)

Publication Number Publication Date
ATE191561T1 true ATE191561T1 (de) 2000-04-15

Family

ID=25272392

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93905022T ATE191561T1 (de) 1992-02-14 1993-02-11 Verfahren und materialien zur bestimmung der teilchenzahl in einem durchflusszytometer

Country Status (12)

Country Link
US (1) US5451525A (de)
EP (1) EP0627080B1 (de)
JP (1) JP3328690B2 (de)
KR (1) KR950700542A (de)
AT (1) ATE191561T1 (de)
AU (1) AU667344B2 (de)
BR (1) BR9305886A (de)
CA (1) CA2129535A1 (de)
DE (1) DE69328296T2 (de)
FI (1) FI943732A (de)
NO (1) NO942989L (de)
WO (1) WO1993016385A1 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5691204A (en) * 1995-04-21 1997-11-25 Abbott Laboratories Compositions and methods for the rapid analysis of reticulocytes
US5882933A (en) * 1995-06-08 1999-03-16 Coulter International Corp. Method for determination of leukocytes and hemoglobin concentration in blood
US5942443A (en) * 1996-06-28 1999-08-24 Caliper Technologies Corporation High throughput screening assay systems in microscale fluidic devices
JP2000510582A (ja) * 1996-04-25 2000-08-15 ゼニコン・サイエンシーズ・コーポレーション 微粒子標識を使用した分析物アッセイ
US5985153A (en) * 1996-06-07 1999-11-16 Immunivest Corporation Magnetic separation apparatus and methods employing an internal magnetic capture gradient and an external transport force
US6660159B1 (en) 1996-06-07 2003-12-09 Immunivest Corporation Magnetic separation apparatus and methods
US6136182A (en) * 1996-06-07 2000-10-24 Immunivest Corporation Magnetic devices and sample chambers for examination and manipulation of cells
US6890426B2 (en) * 1996-06-07 2005-05-10 Immunivest Corporation Magnetic separation apparatus and methods
US6790366B2 (en) * 1996-06-07 2004-09-14 Immunivest Corporation Magnetic separation apparatus and methods
US7666308B2 (en) * 1996-06-07 2010-02-23 Veridex, Llc. Magnetic separation apparatus and methods
US20060000722A1 (en) * 1996-06-28 2006-01-05 Caliper Life Sciences, Inc. High throughput screening assay systems in microscale fluidic devices
EP0907412B1 (de) * 1996-06-28 2008-08-27 Caliper Life Sciences, Inc. Hochdurchsatz-screening-testsystem mittels mikrofluidischer vorrichtungen
JP4209471B2 (ja) 1997-02-20 2009-01-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア プラズモン共鳴粒子、方法、および装置
US6852252B2 (en) 1997-03-12 2005-02-08 William Marsh Rice University Use of metalnanoshells to impede the photo-oxidation of conjugated polymer
US6344272B1 (en) 1997-03-12 2002-02-05 Wm. Marsh Rice University Metal nanoshells
US5976994A (en) * 1997-06-13 1999-11-02 Regents Of The University Of Michigan Method and system for locally annealing a microstructure formed on a substrate and device formed thereby
US6428811B1 (en) 1998-03-11 2002-08-06 Wm. Marsh Rice University Temperature-sensitive polymer/nanoshell composites for photothermally modulated drug delivery
US6699724B1 (en) * 1998-03-11 2004-03-02 Wm. Marsh Rice University Metal nanoshells for biosensing applications
WO2000054026A1 (en) * 1999-03-05 2000-09-14 Hatting-Ks Determination of sperm concentration and viability for artificial insemination
JP3817091B2 (ja) * 1999-07-02 2006-08-30 テルモ株式会社 細胞数測定装置
JP4606543B2 (ja) * 2000-04-13 2011-01-05 パナソニック株式会社 光学特性計測装置における被検溶液量確認方法および計測系制御方法
US6784981B1 (en) 2000-06-02 2004-08-31 Idexx Laboratories, Inc. Flow cytometry-based hematology system
CA2439307A1 (en) 2001-02-23 2002-09-06 Genicon Sciences Corporation Methods for providing extended dynamic range in analyte assays
US7299135B2 (en) * 2005-11-10 2007-11-20 Idexx Laboratories, Inc. Methods for identifying discrete populations (e.g., clusters) of data within a flow cytometer multi-dimensional data set
WO2010135627A1 (en) 2009-05-21 2010-11-25 Intellicyt System and method for separating samples in a continuous flow
US20110129864A1 (en) * 2009-12-02 2011-06-02 Idexx Laboratories, Inc. Method for analyzing lymph node aspirate using multi-angle light scatter flow cytometer
CN103443625B (zh) * 2010-10-21 2017-12-05 耐克思乐生物科学有限责任公司 成像细胞仪的内部聚焦参考珠
JP2016521362A (ja) 2013-04-12 2016-07-21 ベクトン・ディキンソン・アンド・カンパニーＢｅｃｔｏｎ， Ｄｉｃｋｉｎｓｏｎ Ａｎｄ Ｃｏｍｐａｎｙ 細胞分取のための自動セットアップ
WO2015052901A1 (ja) * 2013-10-10 2015-04-16 栄研化学株式会社 採便容器
JP7191975B2 (ja) 2018-03-30 2022-12-19 アイデックス ラボラトリーズ インコーポレイテッド フローサイトメータ、そのレーザ光学アセンブリ、およびレーザ光学アセンブリの組立方法
EP4425235A2 (de) 2020-06-17 2024-09-04 IDEXX Laboratories, Inc. Durchflusszytometer und laseroptikanordnung dafür
CN115436237B (zh) * 2022-09-22 2023-08-01 东莞理工学院 一种颗粒群尺寸分布确定方法、系统、设备及存储介质

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331862A (en) * 1979-02-23 1982-05-25 Ryan Wayne L Method for calibrating a particle counting machine and a calibration standard therefor
US4499052A (en) * 1982-08-30 1985-02-12 Becton, Dickinson And Company Apparatus for distinguishing multiple subpopulations of cells
US4751179A (en) * 1984-05-31 1988-06-14 Coulter Electronics, Inc. Method and reagents for differential determination of four populations of leukocytes in blood
US4661913A (en) * 1984-09-11 1987-04-28 Becton, Dickinson And Company Apparatus and method for the detection and classification of articles using flow cytometry techniques
US5073498A (en) * 1984-12-24 1991-12-17 Caribbean Microparticles Corporation Fluorescent alignment microbeads with broad excitation and emission spectra and its use
US4989978A (en) * 1986-04-04 1991-02-05 Technicon Instruments Corporation Method and apparatus for determining the count per unit volume of particles
US4704891A (en) * 1986-08-29 1987-11-10 Becton, Dickinson And Company Method and materials for calibrating flow cytometers and other analysis instruments
US4888290A (en) * 1987-11-06 1989-12-19 Coulter Corporation Monoclonal antibody specific to HIV antigens
IE76732B1 (en) * 1990-08-07 1997-11-05 Becton Dickinson Co One step test for absolute counts

Also Published As

Publication number Publication date
NO942989L (no) 1994-10-11
DE69328296D1 (de) 2000-05-11
FI943732A0 (fi) 1994-08-12
JP3328690B2 (ja) 2002-09-30
BR9305886A (pt) 1997-08-19
NO942989D0 (no) 1994-08-12
KR950700542A (ko) 1995-01-16
EP0627080A4 (en) 1996-11-20
EP0627080B1 (de) 2000-04-05
EP0627080A1 (de) 1994-12-07
CA2129535A1 (en) 1993-08-15
JPH07503795A (ja) 1995-04-20
WO1993016385A1 (en) 1993-08-19
FI943732A (fi) 1994-10-12
US5451525A (en) 1995-09-19
AU667344B2 (en) 1996-03-21
AU3617093A (en) 1993-09-03
DE69328296T2 (de) 2000-12-21

Similar Documents

Publication Publication Date Title
ATE191561T1 (de) Verfahren und materialien zur bestimmung der teilchenzahl in einem durchflusszytometer
Kachel et al. Fluvo-metricell, a combined cell volume and cell fluorescence analyzer.
Loken et al. Cell discrimination by multiangle light scattering.
US4284355A (en) Automated method for cell volume determination
US5138181A (en) Apparatus for counting and determining at least one leucocytic sub-population
JP4965561B2 (ja) サイトメータ細胞計数及びサイズ測定システム
US4021117A (en) Process for automatic counting and measurement of particles
ATE242879T1 (de) Probenanalyseverfahren mittels bestimmung einer funktion der spezifischen helligkeit
Steinkamp et al. Automated analysis of deoxyribonucleic acid, protein and nuclear to cytoplasmic relationships in tumor cells and gynecologic specimens
JP5260949B2 (ja) 光計測装置および光計測方法
US7130046B2 (en) Data frame selection for cytometer analysis
EP0258982A3 (en) Materials for calibrating flow cytometers and other analysis instruments
AU2011263615A1 (en) Method and device for detecting biological material
JP2020079772A5 (de)
GB1568247A (en) Method for determination of concentration of a suspension
US2819608A (en) Filter testing
Steinkamp et al. Improved multilaser/multiparameter flow cytometer for analysis and sorting of cells and particles
CA2125228A1 (en) Three-color flow cytometry with automatic gating function
EP1291641A3 (de) Durchflusszellesystem zur Löslichkeitsprüfung
US5107527A (en) Method and apparatus for analyzing sludgy materials
US6104490A (en) Multiple pathlength sensor for determining small particle size distribution in high particle concentrations
JPS63139231A (ja) 液体中の微粒子測定方法
US3787123A (en) Method and apparatus for measuring the weight of solid particles suspended in a carrier gas
US5126581A (en) Particle measurement method and apparatus for determining corrected particle diameter
CA1076713A (en) Method and device for measuring the particle size in a slurry or a flow of material

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties