ATE187725T1 - Zwischenprodukte und verfahren zur herstellung von antifolate verbindungen - Google Patents
Zwischenprodukte und verfahren zur herstellung von antifolate verbindungenInfo
- Publication number
- ATE187725T1 ATE187725T1 AT93308177T AT93308177T ATE187725T1 AT E187725 T1 ATE187725 T1 AT E187725T1 AT 93308177 T AT93308177 T AT 93308177T AT 93308177 T AT93308177 T AT 93308177T AT E187725 T1 ATE187725 T1 AT E187725T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- intermediate products
- antifolate compounds
- antifolate
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Radar Systems Or Details Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96157292A | 1992-10-15 | 1992-10-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE187725T1 true ATE187725T1 (de) | 2000-01-15 |
Family
ID=25504654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93308177T ATE187725T1 (de) | 1992-10-15 | 1993-10-13 | Zwischenprodukte und verfahren zur herstellung von antifolate verbindungen |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5969136A (de) |
| EP (1) | EP0593286B1 (de) |
| JP (1) | JPH06211854A (de) |
| KR (1) | KR100283539B1 (de) |
| AT (1) | ATE187725T1 (de) |
| CA (1) | CA2108204A1 (de) |
| DE (1) | DE69327293T2 (de) |
| DK (1) | DK0593286T3 (de) |
| ES (1) | ES2140446T3 (de) |
| GR (1) | GR3032887T3 (de) |
| HU (1) | HU220619B1 (de) |
| IL (1) | IL107229A (de) |
| MX (1) | MX9306396A (de) |
| PT (1) | PT593286E (de) |
| TW (1) | TW274543B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5594139A (en) * | 1993-01-29 | 1997-01-14 | Agouron Pharmaceuticals, Inc. | Processes for preparing antiproliferative garft-inhibiting compounds |
| US5608082A (en) * | 1994-07-28 | 1997-03-04 | Agouron Pharmaceuticals, Inc. | Compounds useful as antiproliferative agents and GARFT inhibitors |
| US5831100A (en) * | 1995-06-07 | 1998-11-03 | Agouron Pharmaceuticals, Inc. | Syntheses of optically pure compounds useful as GARFT inhibitors and their intermediates |
| RU2445434C1 (ru) * | 2010-11-29 | 2012-03-20 | Николай Митрофанович Панин | Шарошка бурового долота |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4814335A (en) * | 1982-12-30 | 1989-03-21 | Biomeasure, Incorporated | Antiviral compounds |
| US4501890A (en) * | 1983-09-26 | 1985-02-26 | Eli Lilly And Company | Trans-(±)-2,4,6-substituted-5,5a,6,7,8,9,9a,10-octahydro-pyrimido[4,5-g]quinolines |
| JP2830008B2 (ja) * | 1988-04-01 | 1998-12-02 | 武田薬品工業株式会社 | 縮合ピリミジン誘導体 |
| US5008391A (en) * | 1989-07-07 | 1991-04-16 | Eli Lilly And Company | Enantioselective synthesis of antifolates |
-
1993
- 1993-07-23 US US08/096,099 patent/US5969136A/en not_active Expired - Fee Related
- 1993-10-11 IL IL107229A patent/IL107229A/en not_active IP Right Cessation
- 1993-10-12 CA CA002108204A patent/CA2108204A1/en not_active Abandoned
- 1993-10-12 TW TW082108430A patent/TW274543B/zh active
- 1993-10-13 DE DE69327293T patent/DE69327293T2/de not_active Expired - Fee Related
- 1993-10-13 DK DK93308177T patent/DK0593286T3/da active
- 1993-10-13 PT PT93308177T patent/PT593286E/pt unknown
- 1993-10-13 ES ES93308177T patent/ES2140446T3/es not_active Expired - Lifetime
- 1993-10-13 EP EP93308177A patent/EP0593286B1/de not_active Expired - Lifetime
- 1993-10-13 AT AT93308177T patent/ATE187725T1/de not_active IP Right Cessation
- 1993-10-14 KR KR1019930021316A patent/KR100283539B1/ko not_active IP Right Cessation
- 1993-10-14 HU HU9302914A patent/HU220619B1/hu not_active IP Right Cessation
- 1993-10-14 MX MX9306396A patent/MX9306396A/es not_active IP Right Cessation
- 1993-10-15 JP JP5258088A patent/JPH06211854A/ja active Pending
-
1995
- 1995-05-30 US US08/453,529 patent/US5486614A/en not_active Expired - Fee Related
-
2000
- 2000-03-07 GR GR20000400582T patent/GR3032887T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| GR3032887T3 (en) | 2000-07-31 |
| HU9302914D0 (en) | 1993-12-28 |
| CA2108204A1 (en) | 1994-04-16 |
| HUT68684A (en) | 1995-07-28 |
| ES2140446T3 (es) | 2000-03-01 |
| EP0593286A2 (de) | 1994-04-20 |
| DE69327293T2 (de) | 2000-05-25 |
| EP0593286A3 (en) | 1994-07-06 |
| US5969136A (en) | 1999-10-19 |
| KR100283539B1 (ko) | 2001-03-02 |
| KR940009153A (ko) | 1994-05-20 |
| TW274543B (de) | 1996-04-21 |
| US5486614A (en) | 1996-01-23 |
| EP0593286B1 (de) | 1999-12-15 |
| JPH06211854A (ja) | 1994-08-02 |
| DK0593286T3 (da) | 2000-03-27 |
| PT593286E (pt) | 2000-05-31 |
| MX9306396A (es) | 1994-05-31 |
| IL107229A0 (en) | 1994-01-25 |
| IL107229A (en) | 1998-06-15 |
| DE69327293D1 (de) | 2000-01-20 |
| HU220619B1 (hu) | 2002-03-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |