TW274543B - - Google Patents

Info

Publication number
TW274543B
TW274543B TW082108430A TW82108430A TW274543B TW 274543 B TW274543 B TW 274543B TW 082108430 A TW082108430 A TW 082108430A TW 82108430 A TW82108430 A TW 82108430A TW 274543 B TW274543 B TW 274543B
Authority
TW
Taiwan
Prior art keywords
susceptable
tetrahydropyrido
neoplasms
pyrimidines
intermediates
Prior art date
Application number
TW082108430A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of TW274543B publication Critical patent/TW274543B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Radar Systems Or Details Thereof (AREA)
TW082108430A 1992-10-15 1993-10-12 TW274543B (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96157292A 1992-10-15 1992-10-15

Publications (1)

Publication Number Publication Date
TW274543B true TW274543B (zh) 1996-04-21

Family

ID=25504654

Family Applications (1)

Application Number Title Priority Date Filing Date
TW082108430A TW274543B (zh) 1992-10-15 1993-10-12

Country Status (15)

Country Link
US (2) US5969136A (zh)
EP (1) EP0593286B1 (zh)
JP (1) JPH06211854A (zh)
KR (1) KR100283539B1 (zh)
AT (1) ATE187725T1 (zh)
CA (1) CA2108204A1 (zh)
DE (1) DE69327293T2 (zh)
DK (1) DK0593286T3 (zh)
ES (1) ES2140446T3 (zh)
GR (1) GR3032887T3 (zh)
HU (1) HU220619B1 (zh)
IL (1) IL107229A (zh)
MX (1) MX9306396A (zh)
PT (1) PT593286E (zh)
TW (1) TW274543B (zh)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5594139A (en) * 1993-01-29 1997-01-14 Agouron Pharmaceuticals, Inc. Processes for preparing antiproliferative garft-inhibiting compounds
US5608082A (en) * 1994-07-28 1997-03-04 Agouron Pharmaceuticals, Inc. Compounds useful as antiproliferative agents and GARFT inhibitors
US5831100A (en) * 1995-06-07 1998-11-03 Agouron Pharmaceuticals, Inc. Syntheses of optically pure compounds useful as GARFT inhibitors and their intermediates
RU2445434C1 (ru) * 2010-11-29 2012-03-20 Николай Митрофанович Панин Шарошка бурового долота

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4814335A (en) * 1982-12-30 1989-03-21 Biomeasure, Incorporated Antiviral compounds
US4501890A (en) * 1983-09-26 1985-02-26 Eli Lilly And Company Trans-(±)-2,4,6-substituted-5,5a,6,7,8,9,9a,10-octahydro-pyrimido[4,5-g]quinolines
JP2830008B2 (ja) * 1988-04-01 1998-12-02 武田薬品工業株式会社 縮合ピリミジン誘導体
US5008391A (en) * 1989-07-07 1991-04-16 Eli Lilly And Company Enantioselective synthesis of antifolates

Also Published As

Publication number Publication date
GR3032887T3 (en) 2000-07-31
HU9302914D0 (en) 1993-12-28
CA2108204A1 (en) 1994-04-16
HUT68684A (en) 1995-07-28
ES2140446T3 (es) 2000-03-01
EP0593286A2 (en) 1994-04-20
DE69327293T2 (de) 2000-05-25
EP0593286A3 (en) 1994-07-06
US5969136A (en) 1999-10-19
KR100283539B1 (ko) 2001-03-02
KR940009153A (ko) 1994-05-20
ATE187725T1 (de) 2000-01-15
US5486614A (en) 1996-01-23
EP0593286B1 (en) 1999-12-15
JPH06211854A (ja) 1994-08-02
DK0593286T3 (da) 2000-03-27
PT593286E (pt) 2000-05-31
MX9306396A (es) 1994-05-31
IL107229A0 (en) 1994-01-25
IL107229A (en) 1998-06-15
DE69327293D1 (de) 2000-01-20
HU220619B1 (hu) 2002-03-28

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