ATE17850T1 - Pyridoxin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. - Google Patents

Pyridoxin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.

Info

Publication number
ATE17850T1
ATE17850T1 AT81201119T AT81201119T ATE17850T1 AT E17850 T1 ATE17850 T1 AT E17850T1 AT 81201119 T AT81201119 T AT 81201119T AT 81201119 T AT81201119 T AT 81201119T AT E17850 T1 ATE17850 T1 AT E17850T1
Authority
AT
Austria
Prior art keywords
manufacture
pharmaceuticals containing
pyridoxine derivatives
pyridoxine
derivatives
Prior art date
Application number
AT81201119T
Other languages
English (en)
Inventor
Alberto Reiner
Original Assignee
D & D Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by D & D Srl filed Critical D & D Srl
Application granted granted Critical
Publication of ATE17850T1 publication Critical patent/ATE17850T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
    • C07D213/67—2-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT81201119T 1980-10-21 1981-10-08 Pyridoxin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. ATE17850T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT25473/80A IT1133963B (it) 1980-10-21 1980-10-21 Derivati piridossinici ad attivita' terapeutica,procedimento per la loro preparazione e relative composizioni farmaceutiche
EP81201119A EP0050385B1 (de) 1980-10-21 1981-10-08 Pyridoxin-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel

Publications (1)

Publication Number Publication Date
ATE17850T1 true ATE17850T1 (de) 1986-02-15

Family

ID=11216796

Family Applications (1)

Application Number Title Priority Date Filing Date
AT81201119T ATE17850T1 (de) 1980-10-21 1981-10-08 Pyridoxin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.

Country Status (17)

Country Link
US (1) US4412996A (de)
EP (1) EP0050385B1 (de)
JP (1) JPS5795962A (de)
AR (1) AR230747A1 (de)
AT (1) ATE17850T1 (de)
AU (1) AU551422B2 (de)
BE (1) BE890798A (de)
CA (1) CA1190922A (de)
DE (1) DE3173724D1 (de)
DK (1) DK462181A (de)
ES (1) ES506375A0 (de)
FR (1) FR2492375B1 (de)
IT (1) IT1133963B (de)
MX (1) MX154715A (de)
NO (1) NO159855C (de)
PT (1) PT73844B (de)
YU (1) YU42439B (de)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717636A (en) * 1970-01-21 1973-02-20 A Esanu Salts of pyridoxine mono-esters
ES411535A1 (es) * 1973-02-12 1976-01-01 Farmabion S A Un procedimiento para la preparacion de esteres del 1-(p- cloro-benzoil)-5-metoxi-2 metilindol-3-acetico, con feno- les.
SE428560B (sv) * 1974-07-22 1983-07-11 Merck & Co Inc Forfarande for framstellning av 5-(2,4-difluorofenyl)salicylsyra.
JPS52156862A (en) * 1976-06-22 1977-12-27 Hisamitsu Pharmaceut Co Inc Novel indoleacetic acid ester derivatives
CH601228A5 (en) * 1977-06-17 1978-06-30 Hisamitsu Pharmaceutical Co Antiinflammatory indomethacin esters active topically and orally
IT1097601B (it) * 1978-07-31 1985-08-31 Crinos Industria Farmaco Derivati della piridosina ad attivita' farmacologica
US4233304A (en) * 1978-07-31 1980-11-11 Crinos Industria Farmacobiologica S.P.A. Pyridoxine derivatives

Also Published As

Publication number Publication date
ES8207142A1 (es) 1982-09-01
MX154715A (es) 1987-12-03
EP0050385B1 (de) 1986-02-05
FR2492375A1 (fr) 1982-04-23
BE890798A (fr) 1982-02-15
CA1190922A (en) 1985-07-23
ES506375A0 (es) 1982-09-01
AU7662281A (en) 1982-09-09
DE3173724D1 (en) 1986-03-20
NO159855C (no) 1989-02-15
AR230747A1 (es) 1984-06-29
FR2492375B1 (fr) 1986-10-10
NO159855B (no) 1988-11-07
US4412996A (en) 1983-11-01
YU251981A (en) 1984-02-29
JPH0343268B2 (de) 1991-07-01
AU551422B2 (en) 1986-05-01
IT1133963B (it) 1986-07-24
IT8025473A0 (it) 1980-10-21
JPS5795962A (en) 1982-06-15
YU42439B (en) 1988-08-31
NO813537L (no) 1982-04-22
EP0050385A1 (de) 1982-04-28
PT73844A (en) 1981-11-01
DK462181A (da) 1982-04-22
PT73844B (en) 1983-01-25

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
REN Ceased due to non-payment of the annual fee