AR230747A1 - Procedimiento para preparar derivados de esteres de piridoxina con los acidos 1-(p-clorobenzoil)-2-metil-5-metoxi-indol-3-acetico o 5-(2,4-difluorfenil)-salicilico - Google Patents

Procedimiento para preparar derivados de esteres de piridoxina con los acidos 1-(p-clorobenzoil)-2-metil-5-metoxi-indol-3-acetico o 5-(2,4-difluorfenil)-salicilico

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Publication number
AR230747A1
AR230747A1 AR287139A AR28713981A AR230747A1 AR 230747 A1 AR230747 A1 AR 230747A1 AR 287139 A AR287139 A AR 287139A AR 28713981 A AR28713981 A AR 28713981A AR 230747 A1 AR230747 A1 AR 230747A1
Authority
AR
Argentina
Prior art keywords
salicilico
piridoxin
difluorfenil
chlorobenzoil
acetico
Prior art date
Application number
AR287139A
Other languages
English (en)
Original Assignee
D & D Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by D & D Srl filed Critical D & D Srl
Application granted granted Critical
Publication of AR230747A1 publication Critical patent/AR230747A1/es

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/281-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62Oxygen or sulfur atoms
    • C07D213/63One oxygen atom
    • C07D213/65One oxygen atom attached in position 3 or 5
    • C07D213/66One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
    • C07D213/672-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AR287139A 1980-10-21 1981-10-19 Procedimiento para preparar derivados de esteres de piridoxina con los acidos 1-(p-clorobenzoil)-2-metil-5-metoxi-indol-3-acetico o 5-(2,4-difluorfenil)-salicilico AR230747A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT25473/80A IT1133963B (it) 1980-10-21 1980-10-21 Derivati piridossinici ad attivita' terapeutica,procedimento per la loro preparazione e relative composizioni farmaceutiche

Publications (1)

Publication Number Publication Date
AR230747A1 true AR230747A1 (es) 1984-06-29

Family

ID=11216796

Family Applications (1)

Application Number Title Priority Date Filing Date
AR287139A AR230747A1 (es) 1980-10-21 1981-10-19 Procedimiento para preparar derivados de esteres de piridoxina con los acidos 1-(p-clorobenzoil)-2-metil-5-metoxi-indol-3-acetico o 5-(2,4-difluorfenil)-salicilico

Country Status (17)

Country Link
US (1) US4412996A (es)
EP (1) EP0050385B1 (es)
JP (1) JPS5795962A (es)
AR (1) AR230747A1 (es)
AT (1) ATE17850T1 (es)
AU (1) AU551422B2 (es)
BE (1) BE890798A (es)
CA (1) CA1190922A (es)
DE (1) DE3173724D1 (es)
DK (1) DK462181A (es)
ES (1) ES506375A0 (es)
FR (1) FR2492375B1 (es)
IT (1) IT1133963B (es)
MX (1) MX154715A (es)
NO (1) NO159855C (es)
PT (1) PT73844B (es)
YU (1) YU42439B (es)

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3717636A (en) * 1970-01-21 1973-02-20 A Esanu Salts of pyridoxine mono-esters
ES411535A1 (es) * 1973-02-12 1976-01-01 Farmabion S A Un procedimiento para la preparacion de esteres del 1-(p- cloro-benzoil)-5-metoxi-2 metilindol-3-acetico, con feno- les.
SE428560B (sv) * 1974-07-22 1983-07-11 Merck & Co Inc Forfarande for framstellning av 5-(2,4-difluorofenyl)salicylsyra.
JPS52156862A (en) * 1976-06-22 1977-12-27 Hisamitsu Pharmaceut Co Inc Novel indoleacetic acid ester derivatives
CH601228A5 (en) * 1977-06-17 1978-06-30 Hisamitsu Pharmaceutical Co Antiinflammatory indomethacin esters active topically and orally
US4233304A (en) * 1978-07-31 1980-11-11 Crinos Industria Farmacobiologica S.P.A. Pyridoxine derivatives
IT1097601B (it) * 1978-07-31 1985-08-31 Crinos Industria Farmaco Derivati della piridosina ad attivita' farmacologica

Also Published As

Publication number Publication date
DE3173724D1 (en) 1986-03-20
IT1133963B (it) 1986-07-24
IT8025473A0 (it) 1980-10-21
JPH0343268B2 (es) 1991-07-01
ATE17850T1 (de) 1986-02-15
CA1190922A (en) 1985-07-23
FR2492375A1 (fr) 1982-04-23
NO159855C (no) 1989-02-15
JPS5795962A (en) 1982-06-15
DK462181A (da) 1982-04-22
US4412996A (en) 1983-11-01
NO159855B (no) 1988-11-07
YU42439B (en) 1988-08-31
ES8207142A1 (es) 1982-09-01
EP0050385A1 (en) 1982-04-28
PT73844A (en) 1981-11-01
EP0050385B1 (en) 1986-02-05
ES506375A0 (es) 1982-09-01
PT73844B (en) 1983-01-25
BE890798A (fr) 1982-02-15
FR2492375B1 (fr) 1986-10-10
AU7662281A (en) 1982-09-09
YU251981A (en) 1984-02-29
AU551422B2 (en) 1986-05-01
MX154715A (es) 1987-12-03
NO813537L (no) 1982-04-22

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