IT1097601B - Derivati della piridosina ad attivita' farmacologica - Google Patents

Derivati della piridosina ad attivita' farmacologica

Info

Publication number
IT1097601B
IT1097601B IT26327/78A IT2632778A IT1097601B IT 1097601 B IT1097601 B IT 1097601B IT 26327/78 A IT26327/78 A IT 26327/78A IT 2632778 A IT2632778 A IT 2632778A IT 1097601 B IT1097601 B IT 1097601B
Authority
IT
Italy
Prior art keywords
pyridosin
phyracacological
activities
phyracacological activities
Prior art date
Application number
IT26327/78A
Other languages
English (en)
Other versions
IT7826327A0 (it
Inventor
Alberto Reiner
Original Assignee
Crinos Industria Farmaco
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Crinos Industria Farmaco filed Critical Crinos Industria Farmaco
Publication of IT7826327A0 publication Critical patent/IT7826327A0/it
Priority to IT26327/78A priority Critical patent/IT1097601B/it
Priority to US06/054,613 priority patent/US4233304A/en
Priority to AU48643/79A priority patent/AU514304B2/en
Priority to AR27729079A priority patent/AR224130A1/es
Priority to YU1753/79A priority patent/YU42488B/xx
Priority to NLAANVRAGE7905774,A priority patent/NL185454C/xx
Priority to AT0517679A priority patent/AT373582B/de
Priority to GB7926223A priority patent/GB2027022B/en
Priority to BE0/196505A priority patent/BE877953A/fr
Priority to CH6972/79A priority patent/CH650774A5/it
Priority to NO792511A priority patent/NO151933C/no
Priority to DK320479A priority patent/DK156651C/da
Priority to MX797079A priority patent/MX155145A/es
Priority to ES482949A priority patent/ES482949A1/es
Priority to MX798273U priority patent/MX5955E/es
Priority to SE7906440A priority patent/SE431645B/sv
Priority to PT70002A priority patent/PT70002A/pt
Priority to DE19792931105 priority patent/DE2931105A1/de
Priority to FR7919714A priority patent/FR2433516A1/fr
Priority to JP54096889A priority patent/JPS6011903B2/ja
Priority to CA332,909A priority patent/CA1123829A/en
Priority to US06/131,020 priority patent/US4260613A/en
Priority to AT388582A priority patent/AT373583B/de
Priority to YU322/83A priority patent/YU42070B/xx
Application granted granted Critical
Publication of IT1097601B publication Critical patent/IT1097601B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C07D213/66—One oxygen atom attached in position 3 or 5 having in position 3 an oxygen atom and in each of the positions 4 and 5 a carbon atom bound to an oxygen, sulphur, or nitrogen atom, e.g. pyridoxal
    • C07D213/67—2-Methyl-3-hydroxy-4,5-bis(hydroxy-methyl)pyridine, i.e. pyridoxine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT26327/78A 1978-07-31 1978-07-31 Derivati della piridosina ad attivita' farmacologica IT1097601B (it)

Priority Applications (24)

Application Number Priority Date Filing Date Title
IT26327/78A IT1097601B (it) 1978-07-31 1978-07-31 Derivati della piridosina ad attivita' farmacologica
US06/054,613 US4233304A (en) 1978-07-31 1979-07-03 Pyridoxine derivatives
AU48643/79A AU514304B2 (en) 1978-07-31 1979-07-04 Pyridoxine derivatives
AR27729079A AR224130A1 (es) 1978-07-31 1979-07-13 Un procedimiento para obtener esteres de piridoxina e isopropiliden piridoxina con acidos benzoico,acetico,propionico y nicotinico 1-sustituidos que tienen actividad antiinflamatoria
YU1753/79A YU42488B (en) 1978-07-31 1979-07-18 Process for obtaining a new pyridoxine derivative
NLAANVRAGE7905774,A NL185454C (nl) 1978-07-31 1979-07-25 Esterderivaat van een anti-inflammatoir werkzaam carbonzuur, werkwijze voor het bereiden daarvan en farmaceutisch preparaat met anti-inflammatoire werking.
AT0517679A AT373582B (de) 1978-07-31 1979-07-26 Verfahren zur herstellung neuer pyridoxinderivate und von deren salzen
GB7926223A GB2027022B (en) 1978-07-31 1979-07-27 Pyridoxine derivatives and their use
BE0/196505A BE877953A (fr) 1978-07-31 1979-07-27 Derives de la pyridoxine
CH6972/79A CH650774A5 (it) 1978-07-31 1979-07-27 Derivati della piridossina ad attivita farmacologica.
MX797079A MX155145A (es) 1978-07-31 1979-07-30 Procedimiento para la preparacion de derivados de piridoxina
DK320479A DK156651C (da) 1978-07-31 1979-07-30 Analogifremgangsmaade til fremstilling af pyridoxinderivater
NO792511A NO151933C (no) 1978-07-31 1979-07-30 Analogifremgangsmaate ved fremstilling av antiinflammatorisk virksomme pyridoksinderivater
ES482949A ES482949A1 (es) 1978-07-31 1979-07-30 Un procedimiento para la preparacion de compuestos derivadosde piridoxina
MX798273U MX5955E (es) 1978-07-31 1979-07-30 Procedimiento para la preparacion de derivados de piridoxina
SE7906440A SE431645B (sv) 1978-07-31 1979-07-30 Pyridoxinderivat och farmaceutisk komposition med anti-inflammatorisk aktivitet och eventuellt analgetisk och/eller anti-pyretisk aktivitet
PT70002A PT70002A (en) 1978-07-31 1979-07-30 Process for preparing novel pyridoxine derivatives
DE19792931105 DE2931105A1 (de) 1978-07-31 1979-07-31 Pyridoxinderivate, verfahren zu ihrer herstellung, sie enthaltende arzneimittel und ihre verwendung bei der behandlung von entzuendungszustaenden
FR7919714A FR2433516A1 (fr) 1978-07-31 1979-07-31 Pyridoxines, leur preparation et leurs utilisations therapeutiques
JP54096889A JPS6011903B2 (ja) 1978-07-31 1979-07-31 ピリドキシン誘導体
CA332,909A CA1123829A (en) 1978-07-31 1979-07-31 Pyridoxine derivatives
US06/131,020 US4260613A (en) 1978-07-31 1980-03-17 Pyridoxine derivatives
AT388582A AT373583B (de) 1978-07-31 1982-10-22 Verfahren zur herstellung neuer pyridoxinderivate und von deren salzen
YU322/83A YU42070B (en) 1978-07-31 1983-02-11 Process for obtaining a new pyridoxine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT26327/78A IT1097601B (it) 1978-07-31 1978-07-31 Derivati della piridosina ad attivita' farmacologica

Publications (2)

Publication Number Publication Date
IT7826327A0 IT7826327A0 (it) 1978-07-31
IT1097601B true IT1097601B (it) 1985-08-31

Family

ID=11219237

Family Applications (1)

Application Number Title Priority Date Filing Date
IT26327/78A IT1097601B (it) 1978-07-31 1978-07-31 Derivati della piridosina ad attivita' farmacologica

Country Status (3)

Country Link
JP (1) JPS6011903B2 (it)
BE (1) BE877953A (it)
IT (1) IT1097601B (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1133963B (it) * 1980-10-21 1986-07-24 D & D Srl Derivati piridossinici ad attivita' terapeutica,procedimento per la loro preparazione e relative composizioni farmaceutiche
RU2629367C1 (ru) * 2016-11-02 2017-08-29 федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) Нестероидное противовоспалительное средство на основе напроксена, обладающее низкой гастротоксичностью

Also Published As

Publication number Publication date
JPS6011903B2 (ja) 1985-03-28
BE877953A (fr) 1979-11-16
IT7826327A0 (it) 1978-07-31
JPS5536483A (en) 1980-03-14

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Legal Events

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ITCP Complementary protection certificate

Free format text: CCP 5

MEDD Supplementary protection certificate for pharmaceutical products: granted

Free format text: CCP 5, 19911220; CRINOS INDUSTRIA FARMACOBIOLOGICA S .P.A.

TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19960910