ATE16489T1 - Aroylimidazolone. - Google Patents
Aroylimidazolone.Info
- Publication number
- ATE16489T1 ATE16489T1 AT82101706T AT82101706T ATE16489T1 AT E16489 T1 ATE16489 T1 AT E16489T1 AT 82101706 T AT82101706 T AT 82101706T AT 82101706 T AT82101706 T AT 82101706T AT E16489 T1 ATE16489 T1 AT E16489T1
- Authority
- AT
- Austria
- Prior art keywords
- aroylimidazolone
- aroylimidazole
- cardiotonics
- ones
- acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Luminescent Compositions (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24088981A | 1981-03-05 | 1981-03-05 | |
| US06/314,312 US4405628A (en) | 1981-03-05 | 1981-10-23 | 4-Pyridylimidazolones and method of use |
| EP82101706A EP0059948B1 (de) | 1981-03-05 | 1982-03-04 | Aroylimidazolone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE16489T1 true ATE16489T1 (de) | 1985-11-15 |
Family
ID=26933806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT82101706T ATE16489T1 (de) | 1981-03-05 | 1982-03-04 | Aroylimidazolone. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4405628A (de) |
| EP (1) | EP0059948B1 (de) |
| KR (1) | KR890000765B1 (de) |
| AT (1) | ATE16489T1 (de) |
| AU (1) | AU557590B2 (de) |
| CA (1) | CA1190550A (de) |
| DE (1) | DE3267352D1 (de) |
| DK (1) | DK168627B1 (de) |
| ES (2) | ES510087A0 (de) |
| GB (1) | GB2096600B (de) |
| GR (1) | GR76518B (de) |
| HK (1) | HK61686A (de) |
| IE (1) | IE52387B1 (de) |
| IL (1) | IL65137A (de) |
| MY (1) | MY8600700A (de) |
| NO (1) | NO157175C (de) |
| NZ (1) | NZ199885A (de) |
| PH (1) | PH18345A (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4367236A (en) * | 1981-11-04 | 1983-01-04 | Merrell Dow Pharmaceuticals Inc. | Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives |
| US4552880A (en) * | 1983-02-15 | 1985-11-12 | Merrell Dow Pharmaceuticals Inc. | Aroylimidazolones |
| US4532250A (en) * | 1983-11-23 | 1985-07-30 | American Hospital Supply Corporation | 5-Heteroarylimidazol-2-ones having cardiotonic activity |
| US4556665A (en) * | 1984-07-09 | 1985-12-03 | Schering A.G. | Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones |
| IL75902A (en) * | 1984-07-30 | 1988-10-31 | Merrell Dow Pharma | Preparation of 1,3-dihydro-4-pyridoyl-2h-imidazol-2-ones |
| US4803278A (en) * | 1984-07-30 | 1989-02-07 | Merrell Dow Pharmaceuticals, Inc. | Preparation of 1,3-dihydro-4-pyridoyl-2H-imidazol-2-ones |
| US4999365A (en) * | 1987-03-20 | 1991-03-12 | Merrell Dow Pharmaceuticals Inc. | Method of reducing reperfusion injury with imidazol-2-thiones |
| ZA881807B (en) * | 1987-03-20 | 1988-09-05 | Merrell Dow Pharmaceuticals Inc. | Method for reducing reperfusion injury with imidazol-2-thiones |
| ZA887662B (en) * | 1987-10-19 | 1989-06-28 | Merrell Dow Pharma | Method for reducing reperfusion injury with imidazol-2-thione-carboxamides |
| AU8212491A (en) * | 1990-06-29 | 1992-01-23 | Upjohn Company, The | Substituted 1-(alkoxyphenyl)piperazines with cns and antihypertensive activity |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| US8034782B2 (en) | 2008-07-16 | 2011-10-11 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| US7879802B2 (en) | 2007-06-04 | 2011-02-01 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| EP2681236B1 (de) | 2011-03-01 | 2018-01-03 | Synergy Pharmaceuticals Inc. | Verfahren zur herstellung von guanylat-cyclase-c-agonisten |
| EP3718557A3 (de) | 2013-02-25 | 2020-10-21 | Bausch Health Ireland Limited | Guanylat-cyclase-rezeptoragonist sp-333 zur verwendung in der darmreinigung |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| AU2014274812B2 (en) | 2013-06-05 | 2018-09-27 | Bausch Health Ireland Limited | Ultra-pure agonists of guanylate cyclase C, method of making and using same |
| KR20220147691A (ko) | 2013-08-09 | 2022-11-03 | 알데릭스, 인코포레이티드 | 인산염 수송을 억제하기 위한 화합물 및 방법 |
| EP3972599A1 (de) | 2019-05-21 | 2022-03-30 | Ardelyx, Inc. | Kombination zur senkung des serum-phosphatspiegels bei einem patienten |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2441933A (en) * | 1945-07-30 | 1948-05-18 | Hoffmann La Roche | Substituted imidazolones and process of making them |
| US3538104A (en) * | 1969-02-28 | 1970-11-03 | Geigy Chem Corp | Pyridyl-2-imidazolones |
| ZA803332B (en) * | 1979-06-18 | 1981-01-28 | Richardson Merrell Inc | Novel 4-aroylimidazol-2-ones |
| NZ193935A (en) * | 1979-06-18 | 1985-05-31 | Richardson Merrell Inc | 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions |
| PH18106A (en) * | 1981-02-18 | 1985-03-21 | Merrell Dow Pharma | Novel-4-aroylimidazol-2-ones |
-
1981
- 1981-10-23 US US06/314,312 patent/US4405628A/en not_active Expired - Lifetime
-
1982
- 1982-03-01 CA CA000397351A patent/CA1190550A/en not_active Expired
- 1982-03-01 IL IL65137A patent/IL65137A/xx not_active IP Right Cessation
- 1982-03-01 PH PH26929A patent/PH18345A/en unknown
- 1982-03-02 NZ NZ199885A patent/NZ199885A/en unknown
- 1982-03-02 GR GR67455A patent/GR76518B/el unknown
- 1982-03-02 AU AU81037/82A patent/AU557590B2/en not_active Ceased
- 1982-03-03 ES ES510087A patent/ES510087A0/es active Granted
- 1982-03-04 GB GB8206412A patent/GB2096600B/en not_active Expired
- 1982-03-04 IE IE491/82A patent/IE52387B1/en not_active IP Right Cessation
- 1982-03-04 NO NO820686A patent/NO157175C/no unknown
- 1982-03-04 DK DK095482A patent/DK168627B1/da not_active IP Right Cessation
- 1982-03-04 EP EP82101706A patent/EP0059948B1/de not_active Expired
- 1982-03-04 AT AT82101706T patent/ATE16489T1/de active
- 1982-03-04 DE DE8282101706T patent/DE3267352D1/de not_active Expired
- 1982-03-04 KR KR8200933A patent/KR890000765B1/ko active
-
1983
- 1983-01-25 ES ES519254A patent/ES519254A0/es active Granted
-
1986
- 1986-08-21 HK HK616/86A patent/HK61686A/xx not_active IP Right Cessation
- 1986-12-30 MY MY700/86A patent/MY8600700A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE3267352D1 (en) | 1985-12-19 |
| ES8305352A1 (es) | 1983-04-16 |
| NO820686L (no) | 1982-09-06 |
| KR830009046A (ko) | 1983-12-17 |
| IE52387B1 (en) | 1987-10-14 |
| ES8402827A1 (es) | 1984-03-01 |
| IL65137A0 (en) | 1982-05-31 |
| GR76518B (de) | 1984-08-10 |
| AU8103782A (en) | 1982-09-09 |
| KR890000765B1 (ko) | 1989-04-05 |
| AU557590B2 (en) | 1986-12-24 |
| IL65137A (en) | 1987-02-27 |
| MY8600700A (en) | 1986-12-31 |
| DK95482A (da) | 1982-09-06 |
| EP0059948B1 (de) | 1985-11-13 |
| US4405628A (en) | 1983-09-20 |
| NZ199885A (en) | 1985-04-30 |
| HK61686A (en) | 1986-08-29 |
| CA1190550A (en) | 1985-07-16 |
| EP0059948A1 (de) | 1982-09-15 |
| DK168627B1 (da) | 1994-05-09 |
| PH18345A (en) | 1985-06-05 |
| NO157175C (no) | 1988-02-03 |
| NO157175B (no) | 1987-10-26 |
| GB2096600A (en) | 1982-10-20 |
| IE820491L (en) | 1982-09-05 |
| ES510087A0 (es) | 1983-04-16 |
| ES519254A0 (es) | 1984-03-01 |
| GB2096600B (en) | 1985-06-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE16489T1 (de) | Aroylimidazolone. | |
| DK505983D0 (da) | Imidazolylalkylthienyl-tetrahydropyridaziner og fremgangsmade til fremstilling deraf | |
| IL66256A (en) | Water containing compositions comprising alkali metal salts of n-substituted-2-pyrrolidone-4-carboxylic acids as humectants | |
| DE3587741T2 (de) | Behandlung von Hautkrankheiten. | |
| ES468525A1 (es) | Procedimiento para la obtencion de nuevas 2-alquilenaminodi-hidropiridinas | |
| DE3670310D1 (de) | Elektrochemische behandlung von ligninen. | |
| ATE7387T1 (de) | Herstellung des calciumsalzes von alpha-hydroxy- gamma-methylmercaptobuttersaeure. | |
| ATE17719T1 (de) | Schwefel-substituierte phenoxypyridine mit antiviraler aktivitaet. | |
| IT7819135A0 (it) | Impiego di difenileteri come algicidi. | |
| DK540586A (da) | Cardiotonisk virksomme thiazoloner | |
| SE8700555D0 (sv) | Purine derivatives, their production and medicaments containing them | |
| DE3686472T2 (de) | Cardiotonische phenyloxazolone. | |
| IT8519042A0 (it) | Impiego di chinoloni nel trattamento di malattie cardiache.! | |
| ES8505351A1 (es) | Un procedimiento para preparar nuevas aroilimidazolonas | |
| AR247730A1 (es) | Derivados del acido 2, 2-dimetil-ciclopropanocarboxilico y composiciones insecticidas y acaricidas que los contienen, su preparacion, materias primas y procedimiento para obtenerlas | |
| IT1137558B (it) | Procedimento per produrre trialogenuri di titanio riducendo teraalogenuri di titanio | |
| ATE69609T1 (de) | Cardiotonische imidazolylphenylpyrrol-2-one. | |
| FI871737A0 (fi) | Kraftanlaeggning med foerbraenning i en fluidiserad baedd. | |
| IT8320239A0 (it) | Derivato del tetraidrotiofenone attivo nelle affezioni broncopolmonari. | |
| ATE51899T1 (de) | Elektrochemische behandlung von ligninen. | |
| ATE75617T1 (de) | Behandlung gewebedegenerativer entzuendungskrankheiten. | |
| ATE64683T1 (de) | Zusammensetzung zur behandlung von haemorroiden. |