HK61686A - Aroylimidazolones and analogues thereof - Google Patents
Aroylimidazolones and analogues thereofInfo
- Publication number
- HK61686A HK61686A HK616/86A HK61686A HK61686A HK 61686 A HK61686 A HK 61686A HK 616/86 A HK616/86 A HK 616/86A HK 61686 A HK61686 A HK 61686A HK 61686 A HK61686 A HK 61686A
- Authority
- HK
- Hong Kong
- Prior art keywords
- aroylimidazolones
- analogues
- aroylimidazole
- cardiotonics
- ones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/70—One oxygen atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Luminescent Compositions (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Steroid Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US24088981A | 1981-03-05 | 1981-03-05 | |
| US06/314,312 US4405628A (en) | 1981-03-05 | 1981-10-23 | 4-Pyridylimidazolones and method of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK61686A true HK61686A (en) | 1986-08-29 |
Family
ID=26933806
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK616/86A HK61686A (en) | 1981-03-05 | 1986-08-21 | Aroylimidazolones and analogues thereof |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4405628A (xx) |
| EP (1) | EP0059948B1 (xx) |
| KR (1) | KR890000765B1 (xx) |
| AT (1) | ATE16489T1 (xx) |
| AU (1) | AU557590B2 (xx) |
| CA (1) | CA1190550A (xx) |
| DE (1) | DE3267352D1 (xx) |
| DK (1) | DK168627B1 (xx) |
| ES (2) | ES510087A0 (xx) |
| GB (1) | GB2096600B (xx) |
| GR (1) | GR76518B (xx) |
| HK (1) | HK61686A (xx) |
| IE (1) | IE52387B1 (xx) |
| IL (1) | IL65137A (xx) |
| MY (1) | MY8600700A (xx) |
| NO (1) | NO157175C (xx) |
| NZ (1) | NZ199885A (xx) |
| PH (1) | PH18345A (xx) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4367236A (en) * | 1981-11-04 | 1983-01-04 | Merrell Dow Pharmaceuticals Inc. | Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives |
| US4552880A (en) * | 1983-02-15 | 1985-11-12 | Merrell Dow Pharmaceuticals Inc. | Aroylimidazolones |
| US4532250A (en) * | 1983-11-23 | 1985-07-30 | American Hospital Supply Corporation | 5-Heteroarylimidazol-2-ones having cardiotonic activity |
| US4556665A (en) * | 1984-07-09 | 1985-12-03 | Schering A.G. | Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones |
| CA1262732C (en) * | 1984-07-30 | 1989-11-07 | PREPARATION OF 1,3-DIHYDRO-4-PYRIDOYL-2H-IMIDAZOL-2-ONES | |
| US4803278A (en) * | 1984-07-30 | 1989-02-07 | Merrell Dow Pharmaceuticals, Inc. | Preparation of 1,3-dihydro-4-pyridoyl-2H-imidazol-2-ones |
| US4999365A (en) * | 1987-03-20 | 1991-03-12 | Merrell Dow Pharmaceuticals Inc. | Method of reducing reperfusion injury with imidazol-2-thiones |
| ZA881807B (en) * | 1987-03-20 | 1988-09-05 | Merrell Dow Pharmaceuticals Inc. | Method for reducing reperfusion injury with imidazol-2-thiones |
| ZA887662B (en) * | 1987-10-19 | 1989-06-28 | Merrell Dow Pharma | Method for reducing reperfusion injury with imidazol-2-thione-carboxamides |
| JPH05507933A (ja) * | 1990-06-29 | 1993-11-11 | ジ・アップジョン・カンパニー | Ｃｎｓおよび抗高血圧活性を有する置換１―（アルコキシフェニル）ピペラジン類 |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2726917C (en) | 2008-06-04 | 2018-06-26 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| WO2010009319A2 (en) | 2008-07-16 | 2010-01-21 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| US9580471B2 (en) | 2011-03-01 | 2017-02-28 | Synergy Pharmaceuticals, Inc. | Process of preparing guanylate cyclase C agonists |
| US9545446B2 (en) | 2013-02-25 | 2017-01-17 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| EP2970384A1 (en) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase and their uses |
| WO2014151200A2 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| JP6606491B2 (ja) | 2013-06-05 | 2019-11-13 | シナジー ファーマシューティカルズ インコーポレイテッド | グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法 |
| JP6694385B2 (ja) | 2013-08-09 | 2020-05-13 | アーデリクス，インコーポレーテッド | リン酸塩輸送阻害のための化合物及び方法 |
| WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2441933A (en) * | 1945-07-30 | 1948-05-18 | Hoffmann La Roche | Substituted imidazolones and process of making them |
| US3538104A (en) * | 1969-02-28 | 1970-11-03 | Geigy Chem Corp | Pyridyl-2-imidazolones |
| NZ193935A (en) * | 1979-06-18 | 1985-05-31 | Richardson Merrell Inc | 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions |
| ZA803332B (en) * | 1979-06-18 | 1981-01-28 | Richardson Merrell Inc | Novel 4-aroylimidazol-2-ones |
| PH18106A (en) * | 1981-02-18 | 1985-03-21 | Merrell Dow Pharma | Novel-4-aroylimidazol-2-ones |
-
1981
- 1981-10-23 US US06/314,312 patent/US4405628A/en not_active Expired - Lifetime
-
1982
- 1982-03-01 CA CA000397351A patent/CA1190550A/en not_active Expired
- 1982-03-01 IL IL65137A patent/IL65137A/xx not_active IP Right Cessation
- 1982-03-01 PH PH26929A patent/PH18345A/en unknown
- 1982-03-02 GR GR67455A patent/GR76518B/el unknown
- 1982-03-02 AU AU81037/82A patent/AU557590B2/en not_active Ceased
- 1982-03-02 NZ NZ199885A patent/NZ199885A/en unknown
- 1982-03-03 ES ES510087A patent/ES510087A0/es active Granted
- 1982-03-04 KR KR8200933A patent/KR890000765B1/ko active
- 1982-03-04 EP EP82101706A patent/EP0059948B1/en not_active Expired
- 1982-03-04 AT AT82101706T patent/ATE16489T1/de active
- 1982-03-04 DE DE8282101706T patent/DE3267352D1/de not_active Expired
- 1982-03-04 IE IE491/82A patent/IE52387B1/en not_active IP Right Cessation
- 1982-03-04 GB GB8206412A patent/GB2096600B/en not_active Expired
- 1982-03-04 DK DK095482A patent/DK168627B1/da not_active IP Right Cessation
- 1982-03-04 NO NO820686A patent/NO157175C/no unknown
-
1983
- 1983-01-25 ES ES519254A patent/ES519254A0/es active Granted
-
1986
- 1986-08-21 HK HK616/86A patent/HK61686A/xx not_active IP Right Cessation
- 1986-12-30 MY MY700/86A patent/MY8600700A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK168627B1 (da) | 1994-05-09 |
| AU8103782A (en) | 1982-09-09 |
| DK95482A (da) | 1982-09-06 |
| IL65137A (en) | 1987-02-27 |
| ES8402827A1 (es) | 1984-03-01 |
| KR890000765B1 (ko) | 1989-04-05 |
| ES519254A0 (es) | 1984-03-01 |
| IE820491L (en) | 1982-09-05 |
| DE3267352D1 (en) | 1985-12-19 |
| EP0059948B1 (en) | 1985-11-13 |
| PH18345A (en) | 1985-06-05 |
| EP0059948A1 (en) | 1982-09-15 |
| GR76518B (xx) | 1984-08-10 |
| IL65137A0 (en) | 1982-05-31 |
| GB2096600A (en) | 1982-10-20 |
| KR830009046A (ko) | 1983-12-17 |
| MY8600700A (en) | 1986-12-31 |
| ATE16489T1 (de) | 1985-11-15 |
| CA1190550A (en) | 1985-07-16 |
| AU557590B2 (en) | 1986-12-24 |
| ES8305352A1 (es) | 1983-04-16 |
| NZ199885A (en) | 1985-04-30 |
| NO157175C (no) | 1988-02-03 |
| US4405628A (en) | 1983-09-20 |
| NO820686L (no) | 1982-09-06 |
| NO157175B (no) | 1987-10-26 |
| IE52387B1 (en) | 1987-10-14 |
| ES510087A0 (es) | 1983-04-16 |
| GB2096600B (en) | 1985-06-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |