ATE160017T1 - Nukleinsäureproben mit über hydrazin-bindungen verbundenen negativ geladenen haptenen - Google Patents

Nukleinsäureproben mit über hydrazin-bindungen verbundenen negativ geladenen haptenen

Info

Publication number
ATE160017T1
ATE160017T1 AT91912973T AT91912973T ATE160017T1 AT E160017 T1 ATE160017 T1 AT E160017T1 AT 91912973 T AT91912973 T AT 91912973T AT 91912973 T AT91912973 T AT 91912973T AT E160017 T1 ATE160017 T1 AT E160017T1
Authority
AT
Austria
Prior art keywords
nucleic acid
protein
probe
negatively charged
connected via
Prior art date
Application number
AT91912973T
Other languages
English (en)
Inventor
Craig W Adams
Original Assignee
Beckman Instruments Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Instruments Inc filed Critical Beckman Instruments Inc
Application granted granted Critical
Publication of ATE160017T1 publication Critical patent/ATE160017T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT91912973T 1990-06-20 1991-06-05 Nukleinsäureproben mit über hydrazin-bindungen verbundenen negativ geladenen haptenen ATE160017T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/541,143 US5552541A (en) 1990-06-20 1990-06-20 Haptenic probes for detecting capture polynucleotides

Publications (1)

Publication Number Publication Date
ATE160017T1 true ATE160017T1 (de) 1997-11-15

Family

ID=24158346

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91912973T ATE160017T1 (de) 1990-06-20 1991-06-05 Nukleinsäureproben mit über hydrazin-bindungen verbundenen negativ geladenen haptenen

Country Status (9)

Country Link
US (1) US5552541A (de)
EP (1) EP0487718B1 (de)
JP (3) JPH05500001U (de)
AT (1) ATE160017T1 (de)
CA (1) CA2059559A1 (de)
DE (1) DE69128127T2 (de)
DK (1) DK0487718T3 (de)
ES (1) ES2110445T3 (de)
WO (1) WO1991019729A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5552541A (en) * 1990-06-20 1996-09-03 Beckman Instruments, Inc. Haptenic probes for detecting capture polynucleotides
FR2679255B1 (fr) * 1991-07-17 1993-10-22 Bio Merieux Procede d'immobilisation d'un fragment nucleique par fixation passive sur un support solide, support solide ainsi obtenu et son utilisation.
DE69714600T2 (de) * 1996-10-08 2003-03-27 Kreatech Biotechnology B.V., Amsterdam Verfahren zur markierung von nukleotiden, markierte nukleotide und nuetzliche zwischenprodukte
DE69839671D1 (de) * 1997-08-15 2008-08-14 Pasteur Institut Mutation innerhalb des connexin 26 gens und bezug zu prelingualer syndromloser taubheit sowie detektionsverfahren
US20030119069A1 (en) * 1999-04-20 2003-06-26 Target Discovery, Inc. Labeling of protein samples
US6764817B1 (en) * 1999-04-20 2004-07-20 Target Discovery, Inc. Methods for conducting metabolic analyses
EP1281966A3 (de) * 2001-07-30 2003-06-18 Fuji Photo Film Co., Ltd. Verfahren und Vorrichtung zur Durchführung einer Rezeptor-Ligand-Reaktion
US6942972B2 (en) * 2001-10-24 2005-09-13 Beckman Coulter, Inc. Efficient synthesis of protein-oligonucleotide conjugates
WO2004090153A2 (en) 2003-04-01 2004-10-21 Eragen Biosciences,Inc. Polymerase inhibitor and method of using same
US20060115848A1 (en) * 2004-07-08 2006-06-01 Andrei Blokhin Nucleic acid end-labeling reagents
CN103592381B (zh) * 2013-10-28 2015-01-14 湖北神舟化工有限公司 高效液相色谱检测磺酸苯肼硫酸盐系列的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
US4547569A (en) * 1982-11-24 1985-10-15 The United States Of America As Represented By The Department Of Health And Human Services Intercalating agents specifying nucleotides
US4490473A (en) * 1983-03-28 1984-12-25 Panab Labeled antibodies and methods
IL73577A (en) * 1983-12-12 1989-10-31 Miles Lab Method and reagent system for detecting dna or rna sequences in a test medium containing single stranded dna or rna using antibodies to intercalation complexes with double stranded nucleic acid
FR2558172B1 (fr) * 1984-01-16 1986-06-13 Inst Nat Sante Rech Med Sonde contenant un acide nucleique modifie et reconnaissance par des anticorps specifiques et utilisation de cette sonde et de ces anticorps specifiques pour detecter et caracteriser une sequence d'adn homologue
US4699876A (en) * 1984-01-27 1987-10-13 E. I. Du Pont De Nemours And Company Nonradiometric polynucleotide probes
US5013831A (en) * 1984-01-30 1991-05-07 Enzo Biochem, Inc. Detectable molecules, method of preparation and use
US4707440A (en) * 1984-01-30 1987-11-17 Enzo Biochem, Inc. Nucleic acid hybridization assay and detectable molecules useful in such assay
US4952685A (en) * 1984-01-30 1990-08-28 Enzo Biochem, Inc. Detectable molecules, method of preparation and use
US4828979A (en) * 1984-11-08 1989-05-09 Life Technologies, Inc. Nucleotide analogs for nucleic acid labeling and detection
US4968602A (en) * 1986-03-05 1990-11-06 Molecular Diagnostics, Inc. Solution-phase single hybridization assay for detecting polynucleotide sequences
CA1315222C (en) * 1986-05-07 1993-03-30 David Mao Polynucleotide probes and a method for their preparation
EP0251527A3 (de) * 1986-06-13 1990-01-24 Panab Laboratories, Inc. Haptenylierte Reagenzien und Immunotests
US5552541A (en) * 1990-06-20 1996-09-03 Beckman Instruments, Inc. Haptenic probes for detecting capture polynucleotides

Also Published As

Publication number Publication date
JPH0884600A (ja) 1996-04-02
CA2059559A1 (en) 1991-12-21
DE69128127T2 (de) 1998-03-05
DE69128127D1 (de) 1997-12-11
JP2686729B2 (ja) 1997-12-08
JPH1023890A (ja) 1998-01-27
JPH05500001U (de) 1993-02-04
EP0487718B1 (de) 1997-11-05
DK0487718T3 (da) 1998-07-27
ES2110445T3 (es) 1998-02-16
EP0487718A1 (de) 1992-06-03
WO1991019729A1 (en) 1991-12-26
US5552541A (en) 1996-09-03

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee