IT1177968B - Recettori monoclonali, indotti da polipeptidi,per leganti proteinici - Google Patents

Recettori monoclonali, indotti da polipeptidi,per leganti proteinici

Info

Publication number
IT1177968B
IT1177968B IT48736/84A IT4873684A IT1177968B IT 1177968 B IT1177968 B IT 1177968B IT 48736/84 A IT48736/84 A IT 48736/84A IT 4873684 A IT4873684 A IT 4873684A IT 1177968 B IT1177968 B IT 1177968B
Authority
IT
Italy
Prior art keywords
polypeptides
induced
protein binders
monoclonal receptors
urine sample
Prior art date
Application number
IT48736/84A
Other languages
English (en)
Other versions
IT8448736A0 (it
IT8448736A1 (it
Inventor
Henry L Niman
Richard A Lerner
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of IT8448736A0 publication Critical patent/IT8448736A0/it
Publication of IT8448736A1 publication Critical patent/IT8448736A1/it
Application granted granted Critical
Publication of IT1177968B publication Critical patent/IT1177968B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Communicable Diseases (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
IT48736/84A 1983-08-17 1984-08-17 Recettori monoclonali, indotti da polipeptidi,per leganti proteinici IT1177968B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52408483A 1983-08-17 1983-08-17

Publications (3)

Publication Number Publication Date
IT8448736A0 IT8448736A0 (it) 1984-08-17
IT8448736A1 IT8448736A1 (it) 1986-02-17
IT1177968B true IT1177968B (it) 1987-09-03

Family

ID=24087698

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48736/84A IT1177968B (it) 1983-08-17 1984-08-17 Recettori monoclonali, indotti da polipeptidi,per leganti proteinici

Country Status (9)

Country Link
EP (2) EP0592026A1 (it)
JP (2) JPS61500068A (it)
AT (1) ATE113962T1 (it)
AU (2) AU580738B2 (it)
CA (1) CA1219232A (it)
DE (1) DE3486356T2 (it)
IT (1) IT1177968B (it)
WO (1) WO1985000807A1 (it)
ZA (1) ZA846439B (it)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591587A (en) * 1983-08-17 1997-01-07 The Scripps Research Institute Polypeptide-induced monoclonal receptors to protein ligands
US5972629A (en) 1984-08-17 1999-10-26 The Scripps Research Institute Method for characterizing antigenic reactivity of biological sample
US4798787A (en) * 1984-09-19 1989-01-17 Cetus Corporation Peptide antibodies and their use in detecting oncogene products
US4898932A (en) * 1985-01-29 1990-02-06 E. I. Du Pont De Nemours And Company Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
US6200764B1 (en) 1985-01-29 2001-03-13 Bayer Corporation Detection, quantitation and classification of ras proteins in body fluids and tissues
US5028527A (en) * 1988-02-22 1991-07-02 Applied Bio Technology Monoclonal antibodies against activated ras proteins with amino acid mutations at position 13 of the protein
US5443956A (en) * 1985-01-29 1995-08-22 Oncogene Science, Inc. Detection, quantitation and classification of RAS proteins in body fluids and tissues
US5084380A (en) * 1985-01-29 1992-01-28 Applied Biotechnology Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
CA1296660C (en) * 1985-01-29 1992-03-03 Walter P. Carney Monoclonal antibody against a ras oncogene p21 related dodecapeptide
US5081230A (en) * 1987-07-08 1992-01-14 E. I. Dupont Denemours And Company Monoclonal antibodies reactive with normal and oncogenic forms of the ras p21 protein
EP0203587A3 (en) * 1985-05-30 1989-08-09 F. Hoffmann-La Roche Ag Ras oncogene peptides and antibodies
EP0206065A3 (en) * 1985-06-27 1989-04-19 James R. Feramisco Method of detecting oncogene and proto-oncogene related proteins in extracellular biological fluids
US6083709A (en) * 1985-08-21 2000-07-04 Osi Pharmaceuticals, Inc. Immunoassay for detection of mutant P53 polypeptide in serum
US5866363A (en) * 1985-08-28 1999-02-02 Pieczenik; George Method and means for sorting and identifying biological information
IL79881A (en) * 1985-08-28 1995-12-08 Pieczenik George Populations of random coding series of oligonucleotides and peptides
JP2726264B2 (ja) * 1986-05-06 1998-03-11 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Ｎ‐ｍｙｃタンパク質のためのアッセイ及び抗体
DK354487A (da) * 1986-07-11 1988-01-12 Noboru Yanaihara Oncogen-relaterede peptider
JPS6374492A (ja) * 1986-09-18 1988-04-04 Hiroshi Shiyuku モノクロ−ナル抗体
FI945466A0 (fi) * 1987-03-23 1994-11-21 Amgen Inc Verihiutaleista peräisin olevaa kasvutekijää tuottavia solulinjoja
JPH02427A (ja) * 1987-07-07 1990-01-05 Max Planck Ges Foerderung Wissenschaft Ev ｃ−ｍｙｂタンパク質のエピトープを認識するモノクローナル抗体、および該抗体を産生するハイブリドーマセルライン
US5094941A (en) * 1987-12-31 1992-03-10 Zymogenetics, Inc. Monoclonal antibodies to PDGF
WO1989008710A1 (en) * 1988-03-08 1989-09-21 E.I. Du Pont De Nemours And Company Monoclonal antibodies reactive with activated and oncogenic ras p21 proteins
DE68929511T2 (de) * 1988-04-22 2004-11-18 Bayer Corp. Nachweis, Quantifizierung und Klassifizierung von RAS-Proteinen in Körperflüssigkeiten und Geweben
EP0354808B1 (en) * 1988-08-12 1997-12-03 Ligand Pharmaceuticals Incorporated Polypeptide-induced monoclonal receptors to protein ligands
JP2552047B2 (ja) * 1990-01-26 1996-11-06 ワシントン リサーチ ファウンデーション 悪性腫瘍の検査方法
GB9103974D0 (en) * 1991-02-26 1991-04-10 Norsk Hydro As Therapeutically useful peptides or peptide fragments

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1981002790A1 (fr) * 1980-03-18 1981-10-01 Ciba Geigy Ag Nouveau support solide pour proteines a des fins analytiques
EP0103893A3 (en) * 1982-09-22 1986-03-19 Daicel Chemical Industries, Ltd. Macrocyclic diesters
CA1252046A (en) * 1982-11-04 1989-04-04 Martin J. Cline Methods for oncogenic detection
ZA84617B (en) * 1983-02-14 1984-09-26 Arup Sen Synthetic polypeptides from viryl oncogenes
US4599306A (en) * 1983-04-15 1986-07-08 Amgen Monoclonal antibodies which specifically bind to human immune interferon
NZ220200A (en) * 1986-05-19 1990-08-28 Viral Technologies Inc Hiv related peptides, antibodies to the peptides and vaccines therefrom
CA1339069C (en) * 1987-11-09 1997-07-29 Henry Lee Niman Polypeptide-induced monoclonal receptors to protein ligand
ES2080047T3 (es) * 1987-11-24 1996-02-01 Abbott Lab Peptidos hiv y metodos para la deteccion de hiv.

Also Published As

Publication number Publication date
IT8448736A0 (it) 1984-08-17
DE3486356D1 (de) 1994-12-15
JPH07284398A (ja) 1995-10-31
DE3486356T2 (de) 1995-06-01
EP0152477A1 (en) 1985-08-28
EP0152477A4 (en) 1987-04-16
JP2592581B2 (ja) 1997-03-19
IT8448736A1 (it) 1986-02-17
AU3395084A (en) 1985-03-12
ATE113962T1 (de) 1994-11-15
CA1219232A (en) 1987-03-17
JPS61500068A (ja) 1986-01-16
ZA846439B (en) 1985-03-27
WO1985000807A1 (en) 1985-02-28
AU633253B2 (en) 1993-01-28
AU580738B2 (en) 1989-02-02
EP0592026A1 (en) 1994-04-13
AU3386089A (en) 1989-08-24
EP0152477B1 (en) 1994-11-09

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