ATE155778T1 - Indolderivate - Google Patents

Indolderivate

Info

Publication number
ATE155778T1
ATE155778T1 AT90121950T AT90121950T ATE155778T1 AT E155778 T1 ATE155778 T1 AT E155778T1 AT 90121950 T AT90121950 T AT 90121950T AT 90121950 T AT90121950 T AT 90121950T AT E155778 T1 ATE155778 T1 AT E155778T1
Authority
AT
Austria
Prior art keywords
group
alkyl
atom
compounds
optionally substituted
Prior art date
Application number
AT90121950T
Other languages
English (en)
Inventor
Haruhiko Kikuchi
Hiroaki Satoh
Makoto Yanai
Toshio Suguro
Koichiro Hagihara
Cho
Original Assignee
Nisshin Flour Milling Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Flour Milling Co filed Critical Nisshin Flour Milling Co
Application granted granted Critical
Publication of ATE155778T1 publication Critical patent/ATE155778T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
AT90121950T 1989-11-17 1990-11-16 Indolderivate ATE155778T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP29749789 1989-11-17

Publications (1)

Publication Number Publication Date
ATE155778T1 true ATE155778T1 (de) 1997-08-15

Family

ID=17847274

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90121950T ATE155778T1 (de) 1989-11-17 1990-11-16 Indolderivate

Country Status (8)

Country Link
US (1) US5124324A (de)
EP (1) EP0429984B1 (de)
KR (1) KR0178023B1 (de)
AT (1) ATE155778T1 (de)
BR (1) BR9005848A (de)
CA (1) CA2030051C (de)
DE (1) DE69031111T2 (de)
ES (1) ES2106015T3 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3026845B2 (ja) * 1991-02-20 2000-03-27 日清製粉株式会社 ピペリジン誘導体
GB9103862D0 (en) * 1991-02-25 1991-04-10 Glaxo Group Ltd Chemical compounds
US5328920A (en) * 1991-04-17 1994-07-12 Hoechst-Roussel Pharmaceuticals Incorporated Substituted (pyridinylamino)-indoles
US5177088A (en) * 1991-04-17 1993-01-05 Hoechst-Roussel Pharmaceuticals Incorporated Substituted 3-(pyridinylamino)-indoles
CA2116024A1 (en) * 1991-08-20 1993-03-04 Francis David King 5-ht4 receptor antagonists
US5852014A (en) * 1992-03-12 1998-12-22 Smithkline Beecham P.L.C. Condensed indole derivatives as 5HT4 -receptor antagonists
ES2132223T3 (es) * 1992-03-12 1999-08-16 Smithkline Beecham Plc Derivados de indol condensados en calidad de antagonistas del receptor 5-ht4.
MX9305947A (es) * 1992-09-29 1994-06-30 Smithkline Beecham Plc Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen.
GR1001378B (el) * 1992-10-08 1993-10-29 Smithkline Beecham Plc Ανταγωνιστές 5-ΗΤ4 πιπεριδυλαλκυλίου.
ES2056728B1 (es) * 1992-10-28 1995-05-01 Smithkline Beecham Plc Nuevos derivados de piperidilo y aminoalquilo con actividad antagonista del receptor 5-ht4
US5874593A (en) 1994-05-16 1999-02-23 Sumitomo Chemical Company, Limited Production process and intermediate of tetrazole compound
WO2004048331A1 (en) * 2002-11-28 2004-06-10 Suven Life Sciences Limited N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands
CN108148059A (zh) * 2018-02-08 2018-06-12 山东齐都药业有限公司 托烷司琼双吲哚杂质的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1220141A (en) * 1981-06-13 1987-04-07 John R. Fozard Treatment of migraine with tropyl benzoate derivatives
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
JPS5936675A (ja) * 1982-07-13 1984-02-28 サンド・アクチエンゲゼルシヤフト 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
US4486441A (en) * 1982-12-03 1984-12-04 Merrell Toraude Et Compagnie Pseudotropyl halogeno-benzoates and their use in migraine treatment
JPS60123485A (ja) * 1983-12-08 1985-07-02 Yoshitomi Pharmaceut Ind Ltd インド−ル−３−カルボキサミド誘導体
DE3445377A1 (de) * 1983-12-23 1985-07-04 Sandoz-Patent-GmbH, 7850 Lörrach Carbocylische und heterocyclische carbonsaeureester und -amide von ueberbrueckten und nicht ueberbrueckten cyclischen stickstoffhaltigen aminen oder alkoholen
US4910193A (en) * 1985-12-16 1990-03-20 Sandoz Ltd. Treatment of gastrointestinal disorders
HU202108B (en) * 1986-07-30 1991-02-28 Sandoz Ag Process for producing pharmaceutical compositions containing serotonine antqgonistic derivatives of indol-carboxylic acid or imidazolyl-methyl-carbazol
DE3885357T2 (de) * 1987-06-29 1994-03-24 Duphar Int Res Anellierte Indolderivate.
GB8720693D0 (en) * 1987-09-03 1987-10-07 Glaxo Group Ltd Chemical compounds
IT1231413B (it) * 1987-09-23 1991-12-04 Angeli Inst Spa Derivati dell'acido benzimidazolin-2-osso-1-carbossilico utili come antagonisti dei recettori 5-ht
GB8814277D0 (en) * 1988-06-16 1988-07-20 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
CA2030051C (en) 2001-08-07
CA2030051A1 (en) 1991-05-18
EP0429984A3 (en) 1992-01-02
ES2106015T3 (es) 1997-11-01
US5124324A (en) 1992-06-23
DE69031111D1 (de) 1997-09-04
EP0429984A2 (de) 1991-06-05
KR0178023B1 (ko) 1999-03-20
EP0429984B1 (de) 1997-07-23
KR910009693A (ko) 1991-06-28
BR9005848A (pt) 1991-09-24
DE69031111T2 (de) 1997-11-13

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