DE69031111D1 - Indolderivate - Google Patents
IndolderivateInfo
- Publication number
- DE69031111D1 DE69031111D1 DE69031111T DE69031111T DE69031111D1 DE 69031111 D1 DE69031111 D1 DE 69031111D1 DE 69031111 T DE69031111 T DE 69031111T DE 69031111 T DE69031111 T DE 69031111T DE 69031111 D1 DE69031111 D1 DE 69031111D1
- Authority
- DE
- Germany
- Prior art keywords
- group
- alkyl
- atom
- compounds
- optionally substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP29749789 | 1989-11-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69031111D1 true DE69031111D1 (de) | 1997-09-04 |
| DE69031111T2 DE69031111T2 (de) | 1997-11-13 |
Family
ID=17847274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69031111T Expired - Fee Related DE69031111T2 (de) | 1989-11-17 | 1990-11-16 | Indolderivate |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5124324A (de) |
| EP (1) | EP0429984B1 (de) |
| KR (1) | KR0178023B1 (de) |
| AT (1) | ATE155778T1 (de) |
| BR (1) | BR9005848A (de) |
| CA (1) | CA2030051C (de) |
| DE (1) | DE69031111T2 (de) |
| ES (1) | ES2106015T3 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3026845B2 (ja) * | 1991-02-20 | 2000-03-27 | 日清製粉株式会社 | ピペリジン誘導体 |
| GB9103862D0 (en) * | 1991-02-25 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
| US5328920A (en) * | 1991-04-17 | 1994-07-12 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted (pyridinylamino)-indoles |
| US5177088A (en) * | 1991-04-17 | 1993-01-05 | Hoechst-Roussel Pharmaceuticals Incorporated | Substituted 3-(pyridinylamino)-indoles |
| AU2435092A (en) * | 1991-08-20 | 1993-03-16 | Smithkline Beecham Plc | 5-ht4 receptor antagonists |
| US5852014A (en) * | 1992-03-12 | 1998-12-22 | Smithkline Beecham P.L.C. | Condensed indole derivatives as 5HT4 -receptor antagonists |
| HU219121B (hu) * | 1992-03-12 | 2001-02-28 | Smithkline Beecham Plc. | Kondenzált indolszármazékok, eljárás előállításukra és ezeket tartalmazó 5-HT4-receptor antagonista hatású gyógyászati készítmények |
| MX9305947A (es) * | 1992-09-29 | 1994-06-30 | Smithkline Beecham Plc | Compuestos antagonistas del receptor 5-ht4, procedimiento para su preparacion y composiciones farmaceuticas que las contienen. |
| GR1001378B (el) * | 1992-10-08 | 1993-10-29 | Smithkline Beecham Plc | Ανταγωνιστές 5-ΗΤ4 πιπεριδυλαλκυλίου. |
| ES2056728B1 (es) * | 1992-10-28 | 1995-05-01 | Smithkline Beecham Plc | Nuevos derivados de piperidilo y aminoalquilo con actividad antagonista del receptor 5-ht4 |
| WO1995031445A1 (fr) | 1994-05-16 | 1995-11-23 | Sumitomo Chemical Company, Limited | Procede pour produire un compose de tetrazole et intermediaire prevu a cet effet |
| WO2004048331A1 (en) * | 2002-11-28 | 2004-06-10 | Suven Life Sciences Limited | N-arylalkyl-3-aminoalkoxyindoles and their use as 5-ht ligands |
| CN108148059A (zh) * | 2018-02-08 | 2018-06-12 | 山东齐都药业有限公司 | 托烷司琼双吲哚杂质的制备方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1220141A (en) * | 1981-06-13 | 1987-04-07 | John R. Fozard | Treatment of migraine with tropyl benzoate derivatives |
| FR2531083B1 (fr) * | 1982-06-29 | 1986-11-28 | Sandoz Sa | Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments |
| JPS5936675A (ja) * | 1982-07-13 | 1984-02-28 | サンド・アクチエンゲゼルシヤフト | 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド |
| US4486441A (en) * | 1982-12-03 | 1984-12-04 | Merrell Toraude Et Compagnie | Pseudotropyl halogeno-benzoates and their use in migraine treatment |
| JPS60123485A (ja) * | 1983-12-08 | 1985-07-02 | Yoshitomi Pharmaceut Ind Ltd | インド−ル−３−カルボキサミド誘導体 |
| DE3445377A1 (de) * | 1983-12-23 | 1985-07-04 | Sandoz-Patent-GmbH, 7850 Lörrach | Carbocylische und heterocyclische carbonsaeureester und -amide von ueberbrueckten und nicht ueberbrueckten cyclischen stickstoffhaltigen aminen oder alkoholen |
| US4910193A (en) * | 1985-12-16 | 1990-03-20 | Sandoz Ltd. | Treatment of gastrointestinal disorders |
| HU895334D0 (en) * | 1986-07-30 | 1990-01-28 | Sandoz Ag | Process for the preparation of nasal pharmaceutical compositions |
| EP0297651B1 (de) * | 1987-06-29 | 1993-11-03 | Duphar International Research B.V | Anellierte Indolderivate |
| GB8720693D0 (en) * | 1987-09-03 | 1987-10-07 | Glaxo Group Ltd | Chemical compounds |
| IT1231413B (it) * | 1987-09-23 | 1991-12-04 | Angeli Inst Spa | Derivati dell'acido benzimidazolin-2-osso-1-carbossilico utili come antagonisti dei recettori 5-ht |
| GB8814277D0 (en) * | 1988-06-16 | 1988-07-20 | Glaxo Group Ltd | Chemical compounds |
-
1990
- 1990-11-15 CA CA002030051A patent/CA2030051C/en not_active Expired - Fee Related
- 1990-11-16 DE DE69031111T patent/DE69031111T2/de not_active Expired - Fee Related
- 1990-11-16 US US07/614,219 patent/US5124324A/en not_active Expired - Lifetime
- 1990-11-16 EP EP90121950A patent/EP0429984B1/de not_active Expired - Lifetime
- 1990-11-16 AT AT90121950T patent/ATE155778T1/de active
- 1990-11-16 ES ES90121950T patent/ES2106015T3/es not_active Expired - Lifetime
- 1990-11-17 KR KR1019900018638A patent/KR0178023B1/ko not_active IP Right Cessation
- 1990-11-19 BR BR909005848A patent/BR9005848A/pt not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0429984A3 (en) | 1992-01-02 |
| ES2106015T3 (es) | 1997-11-01 |
| EP0429984A2 (de) | 1991-06-05 |
| US5124324A (en) | 1992-06-23 |
| EP0429984B1 (de) | 1997-07-23 |
| KR910009693A (ko) | 1991-06-28 |
| CA2030051C (en) | 2001-08-07 |
| KR0178023B1 (ko) | 1999-03-20 |
| BR9005848A (pt) | 1991-09-24 |
| CA2030051A1 (en) | 1991-05-18 |
| DE69031111T2 (de) | 1997-11-13 |
| ATE155778T1 (de) | 1997-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: NISSHIN SEIFUN GROUP INC., TOKIO/TOKYO, JP |
|
| 8339 | Ceased/non-payment of the annual fee |