IT1204459B - Derivati eterociclici - Google Patents

Derivati eterociclici

Info

Publication number
IT1204459B
IT1204459B IT19481/86A IT1948186A IT1204459B IT 1204459 B IT1204459 B IT 1204459B IT 19481/86 A IT19481/86 A IT 19481/86A IT 1948186 A IT1948186 A IT 1948186A IT 1204459 B IT1204459 B IT 1204459B
Authority
IT
Italy
Prior art keywords
group
alkyl group
formula
independently represent
aryl
Prior art date
Application number
IT19481/86A
Other languages
English (en)
Other versions
IT8619481A0 (it
Inventor
Claudio Semeraro
Dino Micheli
Daniele Pieraccili
Giovanni Gaviraghi
Alan David Borthwick
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Spa filed Critical Glaxo Spa
Priority to IT19481/86A priority Critical patent/IT1204459B/it
Publication of IT8619481A0 publication Critical patent/IT8619481A0/it
Priority to EP87301432A priority patent/EP0245918B1/en
Priority to AT87301432T priority patent/ATE88997T1/de
Priority to DE8787301432T priority patent/DE3785695T2/de
Priority to JP62035942A priority patent/JPS62252768A/ja
Priority to US07/266,233 priority patent/US4946851A/en
Priority to SU884356934A priority patent/SU1731049A3/ru
Application granted granted Critical
Publication of IT1204459B publication Critical patent/IT1204459B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Catching Or Destruction (AREA)
IT19481/86A 1986-02-20 1986-02-20 Derivati eterociclici IT1204459B (it)

Priority Applications (7)

Application Number Priority Date Filing Date Title
IT19481/86A IT1204459B (it) 1986-02-20 1986-02-20 Derivati eterociclici
EP87301432A EP0245918B1 (en) 1986-02-20 1987-02-19 1,4-dihydropyridine derivatives
AT87301432T ATE88997T1 (de) 1986-02-20 1987-02-19 1,4-dihydropyridinderivate.
DE8787301432T DE3785695T2 (de) 1986-02-20 1987-02-19 1,4-dihydropyridinderivate.
JP62035942A JPS62252768A (ja) 1986-02-20 1987-02-20 複素環誘導体
US07/266,233 US4946851A (en) 1986-02-20 1988-10-28 1.4-dihydropyridines
SU884356934A SU1731049A3 (ru) 1986-02-20 1988-12-05 Способ получени симметричного эфира 4-замещенной 1,4-дигидропиридин-3,5-дикарбоновой кислоты или его физиологически приемлемых солей

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT19481/86A IT1204459B (it) 1986-02-20 1986-02-20 Derivati eterociclici

Publications (2)

Publication Number Publication Date
IT8619481A0 IT8619481A0 (it) 1986-02-20
IT1204459B true IT1204459B (it) 1989-03-01

Family

ID=11158396

Family Applications (1)

Application Number Title Priority Date Filing Date
IT19481/86A IT1204459B (it) 1986-02-20 1986-02-20 Derivati eterociclici

Country Status (7)

Country Link
US (1) US4946851A (it)
EP (1) EP0245918B1 (it)
JP (1) JPS62252768A (it)
AT (1) ATE88997T1 (it)
DE (1) DE3785695T2 (it)
IT (1) IT1204459B (it)
SU (1) SU1731049A3 (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5514693A (en) * 1988-12-15 1996-05-07 Farmitalia Carlo Erba S.R.L. Imidazolyl and pyridyl derivatives of phenyl substituted 1,4-dihydropyridines and process for their preparation
IL92646A0 (en) * 1988-12-15 1990-08-31 Erba Carlo Spa Imidazolyl and pyridyl derivatives of phenyl substituted 1,4-dihydropyridines,their preparation and pharmaceutical compositions containing them
US5158963A (en) * 1989-08-02 1992-10-27 Kaken Pharmaceutical Co., Ltd. 1-4-dihydropyridine derivative, process for preparing the same and pharmaceutical composition containing the same
WO1991009847A1 (en) * 1989-12-29 1991-07-11 Kaken Pharmaceutical Co., Ltd. Ethynylphenyl derivative, production thereof, and remedy for diseases of circulatory organs containing the same as active ingredient
GB9119983D0 (en) * 1991-09-19 1991-11-06 Erba Carlo Spa Dihydropyridine derivatives useful in antitumor therapy
DK0657432T3 (da) * 1993-12-10 2003-07-07 Bayer Ag Phenylsubstituerede 1,4-dihydropyridiner med cerebral aktivitet
US20080089947A1 (en) * 2006-08-18 2008-04-17 Knox Clayton D Calcium Influx Inhibitors in the Treatment of Ischemia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
ZA776989B (en) * 1976-12-22 1978-09-27 Ciba Geigy Ag A caustic-free process for the production of monochloro-diamino-s-triazines
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln

Also Published As

Publication number Publication date
SU1731049A3 (ru) 1992-04-30
JPS62252768A (ja) 1987-11-04
DE3785695D1 (en) 1993-06-09
DE3785695T2 (de) 1993-08-19
IT8619481A0 (it) 1986-02-20
EP0245918B1 (en) 1993-05-05
US4946851A (en) 1990-08-07
EP0245918A1 (en) 1987-11-19
ATE88997T1 (de) 1993-05-15

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940218