ATE150969T1 - Antipyretische und analgetische zusammensetzungen, die optisch reines r-ketorolac enthalten - Google Patents

Antipyretische und analgetische zusammensetzungen, die optisch reines r-ketorolac enthalten

Info

Publication number
ATE150969T1
ATE150969T1 AT94904855T AT94904855T ATE150969T1 AT E150969 T1 ATE150969 T1 AT E150969T1 AT 94904855 T AT94904855 T AT 94904855T AT 94904855 T AT94904855 T AT 94904855T AT E150969 T1 ATE150969 T1 AT E150969T1
Authority
AT
Austria
Prior art keywords
ketorolac
pain
optically pure
antipyretic
compositions containing
Prior art date
Application number
AT94904855T
Other languages
English (en)
Inventor
Timothy J Barberich
Stephen L Matson
Original Assignee
Sepracor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sepracor Inc filed Critical Sepracor Inc
Application granted granted Critical
Publication of ATE150969T1 publication Critical patent/ATE150969T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT94904855T 1992-12-17 1993-12-17 Antipyretische und analgetische zusammensetzungen, die optisch reines r-ketorolac enthalten ATE150969T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99198192A 1992-12-17 1992-12-17
PCT/US1993/012299 WO1994013283A1 (en) 1992-12-17 1993-12-17 Antipyretic and analgesic methods and compositions containing optically pure r-ketorolac

Publications (1)

Publication Number Publication Date
ATE150969T1 true ATE150969T1 (de) 1997-04-15

Family

ID=25537797

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94904855T ATE150969T1 (de) 1992-12-17 1993-12-17 Antipyretische und analgetische zusammensetzungen, die optisch reines r-ketorolac enthalten

Country Status (14)

Country Link
US (1) US5382591A (de)
EP (1) EP0674511B1 (de)
JP (1) JP2957701B2 (de)
KR (1) KR100264814B1 (de)
AT (1) ATE150969T1 (de)
AU (1) AU696620B2 (de)
CA (1) CA2151724C (de)
DE (1) DE69309492T2 (de)
DK (1) DK0674511T3 (de)
ES (1) ES2100046T3 (de)
FI (1) FI952985A (de)
GR (1) GR3023741T3 (de)
NO (1) NO307546B1 (de)
WO (1) WO1994013283A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464609A (en) * 1990-03-16 1995-11-07 The Procter & Gamble Company Use of ketorolac for treatment of oral diseases and conditions
US5382591A (en) * 1992-12-17 1995-01-17 Sepracor Inc. Antipyretic and analgesic methods using optically pure R-ketorolac
US6160018A (en) * 1995-03-13 2000-12-12 Loma Linda University Medical Center Prophylactic composition and method for alzheimer's Disease
US5955504A (en) * 1995-03-13 1999-09-21 Loma Linda University Medical Center Colorectal chemoprotective composition and method of preventing colorectal cancer
US5981592A (en) * 1995-03-13 1999-11-09 Loma Linda University Medical Center Method and composition for treating cystic fibrosis
DE69841267D1 (de) * 1997-03-10 2009-12-10 Univ Loma Linda Med Verwendung von r-carprofen zur Vorbeugung der Alzheimerschen Krankheit
US6451806B2 (en) 1999-09-29 2002-09-17 Adolor Corporation Methods and compositions involving opioids and antagonists thereof
US6576191B1 (en) * 1999-09-30 2003-06-10 Therox, Inc. Apparatus for blood oxygenation
US6469030B2 (en) 1999-11-29 2002-10-22 Adolor Corporation Methods for the treatment and prevention of ileus
WO2001078721A1 (en) * 2000-04-13 2001-10-25 Mayo Foundation For Medical Education And Research Aβ42 LOWERING AGENTS
US20030027867A1 (en) * 2001-06-29 2003-02-06 Myriad Genetics, Incorporated Use of R-NSAID compounds for anti-HIV treatment
WO2003068159A2 (en) * 2002-02-11 2003-08-21 Wake Forest University Compositions and methods for treating pain using cyclooxygenase-1 inhibitors
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
WO2005065069A2 (en) * 2003-07-11 2005-07-21 Myriad Genetics, Inc. Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease
ATE444732T1 (de) 2003-08-07 2009-10-15 Allergan Inc Zusammensetzungen zur abgabe von therapeutika in die augen und verfahren zu ihrer herstellung und verwendung
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
CN1946906A (zh) * 2004-04-29 2007-04-11 吉斯通护岸系统股份有限公司 用于墙、护墙和类似物的饰面
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
CA2618985A1 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
NZ564789A (en) * 2005-07-22 2010-07-30 Myriad Genetics Inc High drug load formulations and dosage forms
EP2046119A2 (de) * 2006-07-07 2009-04-15 Myriad Genetics, Inc. Behandlung von psychiatrischen störungen
US9192571B2 (en) * 2008-03-03 2015-11-24 Allergan, Inc. Ketorolac tromethamine compositions for treating or preventing ocular pain
US7842714B2 (en) * 2008-03-03 2010-11-30 Allergan, Inc. Ketorolac tromethamine compositions for treating ocular pain
MX2008003230A (es) * 2008-03-07 2009-09-07 Senosiain S A De C V Lab Composicion famaceutica oral que comprende la combinacion de una sal de ketorolaco y vitaminas del complejo b.
CN112094271B (zh) * 2019-06-18 2023-03-21 鲁南制药集团股份有限公司 一种酮咯酸晶型及其制备方法
CN110540542A (zh) * 2019-09-12 2019-12-06 南京海融制药有限公司 一种苯乙酸类化合物的钠盐、结晶形式及其制备方法
WO2021173707A1 (en) * 2020-02-24 2021-09-02 Yinuoke Medicine Science Technology Company Ltd. Compositions and methods for treatment of cytokine storm and cytokine release syndrome
CN114276350B (zh) * 2020-09-28 2023-05-16 鲁南制药集团股份有限公司 一种酮咯酸与吩嗪共晶及其制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4089969A (en) * 1976-07-14 1978-05-16 Syntex (U.S.A.) Inc. 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
EP0264429A4 (de) * 1986-04-16 1990-03-12 Wisconsin Alumni Res Found ENZYMATISCHES VERFAHREN ZUR HERSTELLUNG OPTISCH AKTIVER 1,2-DIHYDRO-3H-PYRROLO-[1,2a]PYRROLE-1-CARBONSÄURE-DERIVATE.
DE69119588T2 (de) * 1990-03-16 1996-11-21 Procter & Gamble Verwendung von ketorolac zur behandlung von periodontitis
JP3541849B2 (ja) * 1991-04-19 2004-07-14 久光製薬株式会社 消炎鎮痛貼付剤
US5382591A (en) * 1992-12-17 1995-01-17 Sepracor Inc. Antipyretic and analgesic methods using optically pure R-ketorolac

Also Published As

Publication number Publication date
WO1994013283A1 (en) 1994-06-23
NO952418D0 (no) 1995-06-16
CA2151724A1 (en) 1994-06-23
JPH08505133A (ja) 1996-06-04
KR100264814B1 (ko) 2000-09-01
NO307546B1 (no) 2000-04-25
FI952985A (fi) 1995-08-16
ES2100046T3 (es) 1997-06-01
AU696620B2 (en) 1998-09-17
FI952985A0 (fi) 1995-06-16
EP0674511B1 (de) 1997-04-02
DK0674511T3 (da) 1997-04-21
GR3023741T3 (en) 1997-09-30
AU5872194A (en) 1994-07-04
CA2151724C (en) 2000-10-31
DE69309492D1 (de) 1997-05-07
DE69309492T2 (de) 1997-07-10
EP0674511A1 (de) 1995-10-04
NO952418L (no) 1995-08-03
KR950703951A (ko) 1995-11-17
US5382591A (en) 1995-01-17
JP2957701B2 (ja) 1999-10-06

Similar Documents

Publication Publication Date Title
ATE150969T1 (de) Antipyretische und analgetische zusammensetzungen, die optisch reines r-ketorolac enthalten
ATE193648T1 (de) Antipyretische und analgetische verfahren und zusammensetzungen, die optisch reines r-etodolac enthalten
RU94042899A (ru) Способ достижения болеутоляющего эффекта, способ лечения и профилактики гипертермии у человека, болеутоляющая и жаропонижающая композиции, содержащие оптически чистый r (-) кетопрофен
DE68919358D1 (de) Zusammensetzung zur behandlung der schizophrenie.
DZ1794A1 (fr) Nouvelle formule pharmaceutique.
HUP0203325A2 (hu) Biciklusos aminosavak, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk
GEP20063720B (en) Triamide-Substituted Indoles, Benzofuranes and Benzothiophenes as Inhibitors of Microsomal Triglyceride Transfer Protein (MTP) and/or Apolipoprotein B (Apo B) Secretion
RU94027680A (ru) Паращитовидный гормон и ралоксифон для увеличения массы кости, фармацевтический состав и способ увеличения костной массы
DK1137416T3 (da) Anvendelse af langkædede N-alkylderivater af deoxynojirimycin til fremstilling af et lægemiddel til behandling af glycolipidophobnings-sygdomme
ATE142877T1 (de) Melatoninderivate zur behandlung von schlafstörungen und zur pre-anästhesie
HUP9904360A2 (hu) Eljárás emesis és központi idegrendszeri rendellenességek kezelésére, optikailag tiszta (+)-norciszaprid alkalmazásával
ES2077199T3 (es) Nuevas piperacinas 1,4-disustituidas, su procedimiento de preparacion y composiciones farmaceuticas que las contienen.
DE69515038D1 (de) Verwendung von raloxifen und dessen analogen zur herstellung eines medikaments zur behandlung viraler erkrankungen
DK0856312T3 (da) Anvendelse af trospiumchlorid til fremstilling af et lægemiddel til behandling af blæresygdomme
HUP0000873A2 (hu) A levobupivakain arcsebészeti alkalmazása
ATE145825T1 (de) Behandlung von erhöhtem blutdruck
NO169229C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 5-(3-alkyl-5-tert.butyl-4-hydroksyfenyl)-2-amino-6h-1,3,4-tiadiaziner
DK0769945T3 (da) Brug af 2-phenyl-3-aroylbenzothiophenderivater til fremstilling af et medikament til behandling af knogler og knoglebrud
PT98764A (pt) Processo para a preparacao de composicoes contendo factor de desenvolvimento de insulina 1 completo para o tratamento terapeutico ou profilactico de estado catabolicos
NO961180L (no) Transdermal anordning inneholdende (E)-2-(p-fluorfenetyl)-3-fluorallylamin for behandling av Alzheimers sykdom
KR920009403A (ko) 수면장해 치료용 이미다조벤조디아제핀
RU95113855A (ru) Способ консервативного лечения ожогов глаз
IT1246050B (it) Impiego dell'eptastigmina nella terapia dell'ictus cerebrale.
RU94027336A (ru) Способ профилактики послеоперационной иммунной недостаточности
NO930083L (no) Sammensetning for behandling av alzheimers sykdom og fremgangsmaate for fremstilling av samme

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee