DE69119588T2 - Verwendung von ketorolac zur behandlung von periodontitis - Google Patents

Verwendung von ketorolac zur behandlung von periodontitis

Info

Publication number
DE69119588T2
DE69119588T2 DE69119588T DE69119588T DE69119588T2 DE 69119588 T2 DE69119588 T2 DE 69119588T2 DE 69119588 T DE69119588 T DE 69119588T DE 69119588 T DE69119588 T DE 69119588T DE 69119588 T2 DE69119588 T2 DE 69119588T2
Authority
DE
Germany
Prior art keywords
ketorolac
treatment
periodontitis
prevention
safe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69119588T
Other languages
English (en)
Other versions
DE69119588D1 (de
Inventor
Gary Kelm
Harvey Pickrum
Matthew Doyle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University of New York
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of DE69119588D1 publication Critical patent/DE69119588D1/de
Application granted granted Critical
Publication of DE69119588T2 publication Critical patent/DE69119588T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
DE69119588T 1990-03-16 1991-03-01 Verwendung von ketorolac zur behandlung von periodontitis Expired - Fee Related DE69119588T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US49469790A 1990-03-16 1990-03-16
US65106191A 1991-02-08 1991-02-08
PCT/US1991/001441 WO1991013609A1 (en) 1990-03-16 1991-03-01 Use of ketorolac for treatment of periodontal disease

Publications (2)

Publication Number Publication Date
DE69119588D1 DE69119588D1 (de) 1996-06-20
DE69119588T2 true DE69119588T2 (de) 1996-11-21

Family

ID=27051510

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69119588T Expired - Fee Related DE69119588T2 (de) 1990-03-16 1991-03-01 Verwendung von ketorolac zur behandlung von periodontitis

Country Status (14)

Country Link
EP (1) EP0519983B1 (de)
JP (1) JP3140050B2 (de)
AT (1) ATE137967T1 (de)
AU (1) AU661818B2 (de)
BR (1) BR9106166A (de)
CA (1) CA2077693C (de)
DE (1) DE69119588T2 (de)
DK (1) DK0519983T3 (de)
ES (1) ES2086536T3 (de)
GR (1) GR3019928T3 (de)
IE (1) IE910886A1 (de)
NZ (1) NZ237449A (de)
SG (1) SG54157A1 (de)
WO (1) WO1991013609A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5464609A (en) * 1990-03-16 1995-11-07 The Procter & Gamble Company Use of ketorolac for treatment of oral diseases and conditions
US5382591A (en) * 1992-12-17 1995-01-17 Sepracor Inc. Antipyretic and analgesic methods using optically pure R-ketorolac
DE4300697C1 (de) * 1993-01-13 1994-05-19 Roemmers Sa Keterolac-Derivat mit wesentlich geringerer gastrointestinaler Reizung und Ulzeration
US5626838A (en) * 1995-03-13 1997-05-06 The Procter & Gamble Company Use of ketorolac for treatment of squamous cell carcinomas of the oral cavity or oropharynx
US5807541A (en) * 1996-04-22 1998-09-15 Sepracor, Inc. NSAID/fluoride periodontal compositions and methods
BRPI0302736B8 (pt) 2003-06-02 2021-05-25 Ems S/A composição farmacêutica a base de cetorolaco ou de um de seus sais farmaceuticamente aceitáveis para uso sublingual
US7732478B2 (en) 2004-01-09 2010-06-08 The Trustees Of Columbia University In The City Of New York Methods for facilitating metabolic control

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2629884A1 (de) * 1975-07-04 1977-01-20 Gaba Ag Mund- und zahnpflegemittel
US4919939A (en) * 1986-04-29 1990-04-24 Pharmetrix Corporation Periodontal disease treatment system
DE3870111D1 (de) * 1987-09-11 1992-05-21 Syntex Inc Schutzmittel fuer augenzubereitungen.
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease

Also Published As

Publication number Publication date
EP0519983B1 (de) 1996-05-15
DE69119588D1 (de) 1996-06-20
EP0519983A4 (en) 1993-03-10
WO1991013609A1 (en) 1991-09-19
GR3019928T3 (en) 1996-08-31
AU7472991A (en) 1991-10-10
AU661818B2 (en) 1995-08-10
SG54157A1 (en) 1998-11-16
IE910886A1 (en) 1991-09-25
NZ237449A (en) 1996-10-28
DK0519983T3 (da) 1996-10-14
JP3140050B2 (ja) 2001-03-05
BR9106166A (pt) 1993-03-16
EP0519983A1 (de) 1992-12-30
CA2077693C (en) 1997-03-04
JPH05505400A (ja) 1993-08-12
CA2077693A1 (en) 1991-09-17
ES2086536T3 (es) 1996-07-01
ATE137967T1 (de) 1996-06-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: THE TRUSTESS OF COLUMBIA UNIVERSITY IN THE CITY OF

8339 Ceased/non-payment of the annual fee