ATE143412T1 - Deletionsmutanten von bovinem herpuvirus-1, auf diese basierte impfstoffe,diagnosesätze für den nachweis von bovinem herpesvirus-1 - Google Patents
Deletionsmutanten von bovinem herpuvirus-1, auf diese basierte impfstoffe,diagnosesätze für den nachweis von bovinem herpesvirus-1Info
- Publication number
- ATE143412T1 ATE143412T1 AT92914642T AT92914642T ATE143412T1 AT E143412 T1 ATE143412 T1 AT E143412T1 AT 92914642 T AT92914642 T AT 92914642T AT 92914642 T AT92914642 T AT 92914642T AT E143412 T1 ATE143412 T1 AT E143412T1
- Authority
- AT
- Austria
- Prior art keywords
- bovine
- herpuvirus
- detection
- gene
- deletion mutants
- Prior art date
Links
- 230000037430 deletion Effects 0.000 title abstract 4
- 238000012217 deletion Methods 0.000 title abstract 4
- 241000701083 Bovine alphaherpesvirus 1 Species 0.000 title abstract 2
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 241000283690 Bos taurus Species 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 4
- 108090000288 Glycoproteins Proteins 0.000 abstract 4
- 101150072564 gE gene Proteins 0.000 abstract 2
- 238000009007 Diagnostic Kit Methods 0.000 abstract 1
- 108020004440 Thymidine kinase Proteins 0.000 abstract 1
- 101150030521 gI gene Proteins 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
- A61K39/265—Infectious rhinotracheitis virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
- C07K16/087—Herpes simplex virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16732—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16741—Use of virus, viral particle or viral elements as a vector
- C12N2710/16743—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL9100989A NL9100989A (nl) | 1991-06-07 | 1991-06-07 | Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE143412T1 true ATE143412T1 (de) | 1996-10-15 |
Family
ID=19859344
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92914642T ATE143412T1 (de) | 1991-06-07 | 1992-06-05 | Deletionsmutanten von bovinem herpuvirus-1, auf diese basierte impfstoffe,diagnosesätze für den nachweis von bovinem herpesvirus-1 |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US5676951A (enExample) |
| EP (1) | EP0587805B2 (enExample) |
| JP (3) | JPH06508032A (enExample) |
| KR (1) | KR100293761B1 (enExample) |
| AT (1) | ATE143412T1 (enExample) |
| AU (1) | AU671802B2 (enExample) |
| CA (1) | CA2110519C (enExample) |
| CZ (1) | CZ283283B6 (enExample) |
| DE (1) | DE69214146T3 (enExample) |
| DK (1) | DK0587805T4 (enExample) |
| ES (1) | ES2097340T5 (enExample) |
| FI (1) | FI110060B (enExample) |
| GR (1) | GR3022138T3 (enExample) |
| HU (1) | HU219602B (enExample) |
| NL (1) | NL9100989A (enExample) |
| NO (2) | NO934431D0 (enExample) |
| RU (1) | RU2170254C2 (enExample) |
| SK (1) | SK280862B6 (enExample) |
| UA (1) | UA40571C2 (enExample) |
| WO (1) | WO1992021751A1 (enExample) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5783195A (en) * | 1991-07-18 | 1998-07-21 | Syntro Corporation | Recombinant infectious bovine rhinotracheitis virus S-IBR-052 and uses thereof |
| US6410033B1 (en) | 1987-07-27 | 2002-06-25 | Syntro Corporation | Recombinant infectious bovine rhinotracheitis virus |
| FR2693472B1 (fr) * | 1992-06-26 | 1994-12-23 | Rhone Merieux | Mutants du virus de la rhinotrachéite infectieuse bovine, délétés dans l'un des gènes des glycoprotéines mineures, vaccins préparés à partir de ces souches, méthodes de production et méthodes d'utilisation. |
| DE69132404T2 (de) * | 1990-10-04 | 2001-02-15 | Research Corp. Technologies, Inc. | Varicella-zoster virusantigen |
| NL9100989A (nl) * | 1991-06-07 | 1993-01-04 | Stichting Centr Diergeneeskund | Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1. |
| CA2113641A1 (en) * | 1991-07-18 | 1993-02-04 | Mark D. Cochran | Recombinant infectious bovine rhinotracheitis virus |
| DE4141400A1 (de) * | 1991-12-16 | 1993-06-17 | Bayer Ag | Impfstoffe auf basis geaenderter boviner herpesviren typ 1 |
| AU676471B2 (en) * | 1992-03-20 | 1997-03-13 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Fungus-responsive chimaeric gene |
| WO1994024296A2 (en) * | 1993-04-19 | 1994-10-27 | University Of Saskatchewan | Recombinant bovine herpesvirus type 1 vaccines |
| CA2136381A1 (en) * | 1993-11-23 | 1995-05-24 | Gunther Keil | Vector vaccines of bovine herpesvirus 1 |
| ES2074965B1 (es) * | 1994-01-31 | 1996-05-01 | Hipra Lab Sa | Virus mutante recombinante de rinotraqueitis infecciosa bovina y vacunas que lo contienen. |
| ES2088371B1 (es) * | 1995-02-01 | 1997-04-16 | Hipra Lab Sa | Procedimiento para la produccion en forma recombinante de antigenos de la glicoproteina ge de herpesvirus bovino tipo 1 y su uso en la diferenciacion serologica entre animales infectados y animales vacunados. |
| US6221360B1 (en) * | 1996-02-26 | 2001-04-24 | Kansas State University Research Foundation | Infectious bovine rhinotracheitis vaccines and methods |
| US6284251B1 (en) | 1996-02-26 | 2001-09-04 | Kansas State University Research Foundation | BHV-1 gene-deleted virus vaccine |
| EP2365082A1 (en) | 2000-06-27 | 2011-09-14 | Pfizer Animal Health S.A. | BVDV virus-like particles |
| US6935866B2 (en) * | 2002-04-02 | 2005-08-30 | Adc Telecommunications, Inc. | Card edge coaxial connector |
| BRPI0318114B8 (pt) | 2003-02-19 | 2022-07-05 | Merial Ltd | Vacinação ou imunização utilizando um regime de iniciação-reforço |
| WO2009009892A1 (en) * | 2007-07-19 | 2009-01-22 | Azad Kumar Kaushik | Engineered scfv against bovine herpes virus type i |
| EP2108375A1 (de) * | 2008-04-10 | 2009-10-14 | Riemser Arzneimittel AG | Lebendimpfstoffzusammensetzung |
| CN102649948B (zh) * | 2011-02-23 | 2016-05-25 | 华中农业大学 | 牛传染性鼻气管炎ΔTK/ΔgE基因缺失标志活疫苗及制备方法 |
| US8877211B2 (en) | 2011-06-27 | 2014-11-04 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Bovine herpes virus vaccine with multiple mutations |
| EP2870251A4 (en) * | 2011-07-05 | 2017-08-30 | The State of Queensland acting through The Department of Agriculture and Fisheries | Recombinant low virulence bovine herpesvirus 1 (bohv-1) vaccine vectors |
| CN103923884B (zh) * | 2014-02-21 | 2017-03-29 | 普莱柯生物工程股份有限公司 | 一种猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用 |
| EP2942628A1 (en) | 2014-05-08 | 2015-11-11 | In3diagnostic S.r.l. | Kit and in vitro method for identifying Bovine Herpes Virus 1 infections |
| US10690669B2 (en) * | 2014-08-01 | 2020-06-23 | Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College | Bovine herpesvirus detection and treatment |
| JP2023533333A (ja) * | 2020-07-10 | 2023-08-02 | マクマスター・ユニバーシティ | がん治療に使用するための遺伝子組換えウシヘルペスウイルス１型（ｂｈｖ－１） |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4703011A (en) * | 1985-11-12 | 1987-10-27 | Novagene, Inc. | Thymidine kinase deletion mutants of bovine herpesvirus-1 |
| US5593873A (en) * | 1986-01-27 | 1997-01-14 | Syntro Corporation | Recombinant infectious bovine rhinotracheitis virus |
| US4992051A (en) * | 1987-11-03 | 1991-02-12 | Novagene, Inc. | Infectious bovine rhinotracheitis virus mutants, methods for the production of same and methods for the use of same |
| AU2888089A (en) * | 1988-01-26 | 1989-07-27 | Baylor College Of Medicine | Infectious bovine rhinotracheitis virus insertion mutants, vaccines containing same, and methods for the production and use of same |
| AU3579089A (en) * | 1988-05-03 | 1989-11-29 | Upjohn Company, The | Glycoprotein h of herpes viruses |
| NL9100989A (nl) * | 1991-06-07 | 1993-01-04 | Stichting Centr Diergeneeskund | Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1. |
| DE4141400A1 (de) * | 1991-12-16 | 1993-06-17 | Bayer Ag | Impfstoffe auf basis geaenderter boviner herpesviren typ 1 |
-
1991
- 1991-06-07 NL NL9100989A patent/NL9100989A/nl not_active Application Discontinuation
-
1992
- 1992-06-05 AU AU22750/92A patent/AU671802B2/en not_active Expired
- 1992-06-05 AT AT92914642T patent/ATE143412T1/de active
- 1992-06-05 KR KR1019930703773A patent/KR100293761B1/ko not_active Expired - Lifetime
- 1992-06-05 HU HU9303470A patent/HU219602B/hu unknown
- 1992-06-05 CA CA002110519A patent/CA2110519C/en not_active Expired - Lifetime
- 1992-06-05 WO PCT/NL1992/000097 patent/WO1992021751A1/en not_active Ceased
- 1992-06-05 DK DK92914642T patent/DK0587805T4/da active
- 1992-06-05 US US08/150,203 patent/US5676951A/en not_active Expired - Lifetime
- 1992-06-05 JP JP5500368A patent/JPH06508032A/ja active Pending
- 1992-06-05 UA UA93004426A patent/UA40571C2/uk unknown
- 1992-06-05 CZ CS932646A patent/CZ283283B6/cs not_active IP Right Cessation
- 1992-06-05 ES ES92914642T patent/ES2097340T5/es not_active Expired - Lifetime
- 1992-06-05 RU RU93058614/13A patent/RU2170254C2/ru active
- 1992-06-05 EP EP92914642A patent/EP0587805B2/en not_active Expired - Lifetime
- 1992-06-05 DE DE69214146T patent/DE69214146T3/de not_active Expired - Lifetime
- 1992-06-05 SK SK1375-93A patent/SK280862B6/sk not_active IP Right Cessation
-
1993
- 1993-12-06 NO NO934431D patent/NO934431D0/no unknown
- 1993-12-06 NO NO934431A patent/NO934431L/no unknown
- 1993-12-07 FI FI935459A patent/FI110060B/fi not_active IP Right Cessation
-
1995
- 1995-05-31 US US08/454,730 patent/US5789177A/en not_active Expired - Lifetime
-
1996
- 1996-12-23 GR GR960403580T patent/GR3022138T3/el unknown
-
1997
- 1997-10-14 US US08/949,788 patent/US6403097B1/en not_active Expired - Lifetime
-
2006
- 2006-04-11 JP JP2006109215A patent/JP4486055B2/ja not_active Expired - Lifetime
-
2009
- 2009-11-26 JP JP2009268316A patent/JP2010104367A/ja active Pending
Also Published As
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| UEP | Publication of translation of european patent specification | ||
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