ATE143412T1 - Deletionsmutanten von bovinem herpuvirus-1, auf diese basierte impfstoffe,diagnosesätze für den nachweis von bovinem herpesvirus-1 - Google Patents

Deletionsmutanten von bovinem herpuvirus-1, auf diese basierte impfstoffe,diagnosesätze für den nachweis von bovinem herpesvirus-1

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Publication number
ATE143412T1
ATE143412T1 AT92914642T AT92914642T ATE143412T1 AT E143412 T1 ATE143412 T1 AT E143412T1 AT 92914642 T AT92914642 T AT 92914642T AT 92914642 T AT92914642 T AT 92914642T AT E143412 T1 ATE143412 T1 AT E143412T1
Authority
AT
Austria
Prior art keywords
bovine
herpuvirus
detection
gene
deletion mutants
Prior art date
Application number
AT92914642T
Other languages
English (en)
Inventor
Franciscus Antonius Rijsewijk
Oirschot Johannes Theodoru Van
Roger Kamiel Maes
Original Assignee
Stichting Centr Diergeneeskund
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19859344&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE143412(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Stichting Centr Diergeneeskund filed Critical Stichting Centr Diergeneeskund
Application granted granted Critical
Publication of ATE143412T1 publication Critical patent/ATE143412T1/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A61K39/265—Infectious rhinotracheitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • C07K16/087—Herpes simplex virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16732—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16741—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16743—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT92914642T 1991-06-07 1992-06-05 Deletionsmutanten von bovinem herpuvirus-1, auf diese basierte impfstoffe,diagnosesätze für den nachweis von bovinem herpesvirus-1 ATE143412T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL9100989A NL9100989A (nl) 1991-06-07 1991-06-07 Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1.

Publications (1)

Publication Number Publication Date
ATE143412T1 true ATE143412T1 (de) 1996-10-15

Family

ID=19859344

Family Applications (1)

Application Number Title Priority Date Filing Date
AT92914642T ATE143412T1 (de) 1991-06-07 1992-06-05 Deletionsmutanten von bovinem herpuvirus-1, auf diese basierte impfstoffe,diagnosesätze für den nachweis von bovinem herpesvirus-1

Country Status (20)

Country Link
US (3) US5676951A (de)
EP (1) EP0587805B2 (de)
JP (3) JPH06508032A (de)
KR (1) KR100293761B1 (de)
AT (1) ATE143412T1 (de)
AU (1) AU671802B2 (de)
CA (1) CA2110519C (de)
CZ (1) CZ283283B6 (de)
DE (1) DE69214146T3 (de)
DK (1) DK0587805T4 (de)
ES (1) ES2097340T5 (de)
FI (1) FI110060B (de)
GR (1) GR3022138T3 (de)
HU (1) HU219602B (de)
NL (1) NL9100989A (de)
NO (2) NO934431L (de)
RU (1) RU2170254C2 (de)
SK (1) SK280862B6 (de)
UA (1) UA40571C2 (de)
WO (1) WO1992021751A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410033B1 (en) 1987-07-27 2002-06-25 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
US5783195A (en) * 1991-07-18 1998-07-21 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus S-IBR-052 and uses thereof
FR2693472B1 (fr) * 1992-06-26 1994-12-23 Rhone Merieux Mutants du virus de la rhinotrachéite infectieuse bovine, délétés dans l'un des gènes des glycoprotéines mineures, vaccins préparés à partir de ces souches, méthodes de production et méthodes d'utilisation.
KR920703614A (ko) * 1990-10-04 1992-12-18 티모시 제이. 렉카르트 바리셀라-조스터 바이러스 항원
NL9100989A (nl) * 1991-06-07 1993-01-04 Stichting Centr Diergeneeskund Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1.
EP0598759A4 (de) * 1991-07-18 1998-06-03 Syntro Corp Rekombinanter infektiöser rinder rhinotracheitis virus.
DE4141400A1 (de) * 1991-12-16 1993-06-17 Bayer Ag Impfstoffe auf basis geaenderter boviner herpesviren typ 1
AU676471B2 (en) * 1992-03-20 1997-03-13 Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. Fungus-responsive chimaeric gene
WO1994024296A2 (en) * 1993-04-19 1994-10-27 University Of Saskatchewan Recombinant bovine herpesvirus type 1 vaccines
CA2136381A1 (en) * 1993-11-23 1995-05-24 Gunther Keil Vector vaccines of bovine herpesvirus 1
ES2074965B1 (es) * 1994-01-31 1996-05-01 Hipra Lab Sa Virus mutante recombinante de rinotraqueitis infecciosa bovina y vacunas que lo contienen.
ES2088371B1 (es) * 1995-02-01 1997-04-16 Hipra Lab Sa Procedimiento para la produccion en forma recombinante de antigenos de la glicoproteina ge de herpesvirus bovino tipo 1 y su uso en la diferenciacion serologica entre animales infectados y animales vacunados.
US6221360B1 (en) * 1996-02-26 2001-04-24 Kansas State University Research Foundation Infectious bovine rhinotracheitis vaccines and methods
US6284251B1 (en) 1996-02-26 2001-09-04 Kansas State University Research Foundation BHV-1 gene-deleted virus vaccine
EP1170367A1 (de) 2000-06-27 2002-01-09 Bayer Ag BVDV virusähnliche Partikeln
US6935866B2 (en) * 2002-04-02 2005-08-30 Adc Telecommunications, Inc. Card edge coaxial connector
EP1594537B1 (de) 2003-02-19 2012-10-24 Merial Vakzinierung oder immunisierung gegen brsv, bhv-1,bvdv,bpi-3, die ein prime-boost-verfahren verwendet
CA2693137C (en) * 2007-07-19 2014-04-08 Azad Kumar Kaushik Engineered scfv against bovine herpes virus type i
EP2108375A1 (de) * 2008-04-10 2009-10-14 Riemser Arzneimittel AG Lebendimpfstoffzusammensetzung
CN102649948B (zh) * 2011-02-23 2016-05-25 华中农业大学 牛传染性鼻气管炎ΔTK/ΔgE基因缺失标志活疫苗及制备方法
US8877211B2 (en) 2011-06-27 2014-11-04 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Bovine herpes virus vaccine with multiple mutations
US9381240B2 (en) * 2011-07-05 2016-07-05 The State Of Queensland Acting Through The Department Of Agriculture And Fisheries Recombinant low virulence bovine herpesvirus-1 (BoHV-1) vaccine vectors
CN105368791A (zh) * 2014-02-21 2016-03-02 普莱柯生物工程股份有限公司 一种猪伪狂犬病病毒基因缺失株、疫苗组合物及其制备方法和应用
EP2942628A1 (de) 2014-05-08 2015-11-11 In3diagnostic S.r.l. Kit und in-vitro-Methode zur Identifizierung Bovine Herpes Virus 1-Infektionen
EP3779445A1 (de) * 2014-08-01 2021-02-17 Board of Supervisors of Louisiana State University and Agricultural and Mechanical College Nachweis und behandlung von bovinem herpesvirus

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4703011A (en) * 1985-11-12 1987-10-27 Novagene, Inc. Thymidine kinase deletion mutants of bovine herpesvirus-1
US5593873A (en) * 1986-01-27 1997-01-14 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
US4992051A (en) * 1987-11-03 1991-02-12 Novagene, Inc. Infectious bovine rhinotracheitis virus mutants, methods for the production of same and methods for the use of same
JPH0235079A (ja) * 1988-01-26 1990-02-05 Novagene Inc 感染性ウシ鼻気管炎ウイルスの挿入突然変異体
WO1989010965A2 (en) * 1988-05-03 1989-11-16 The Upjohn Company Glycoprotein h of herpes viruses
NL9100989A (nl) * 1991-06-07 1993-01-04 Stichting Centr Diergeneeskund Bovine herpesvirus type 1 deletiemutanten, daarop gebaseerde vaccins, diagnostische kits voor detectie van bovine herpesvirus type 1.
DE4141400A1 (de) * 1991-12-16 1993-06-17 Bayer Ag Impfstoffe auf basis geaenderter boviner herpesviren typ 1

Also Published As

Publication number Publication date
FI935459A0 (fi) 1993-12-07
RU2170254C2 (ru) 2001-07-10
ES2097340T5 (es) 2005-04-16
ES2097340T3 (es) 1997-04-01
CA2110519C (en) 2001-07-17
JP2006296426A (ja) 2006-11-02
JP2010104367A (ja) 2010-05-13
NO934431D0 (no) 1993-12-06
CA2110519A1 (en) 1992-12-10
US6403097B1 (en) 2002-06-11
HU219602B (hu) 2001-05-28
FI935459A (fi) 1994-02-07
AU2275092A (en) 1993-01-08
EP0587805B2 (de) 2004-09-22
DE69214146T2 (de) 1997-02-13
KR100293761B1 (ko) 2001-10-22
JPH06508032A (ja) 1994-09-14
AU671802B2 (en) 1996-09-12
CZ264693A3 (en) 1994-05-18
EP0587805B1 (de) 1996-09-25
DE69214146D1 (de) 1996-10-31
SK280862B6 (sk) 2000-08-14
EP0587805A1 (de) 1994-03-23
US5676951A (en) 1997-10-14
UA40571C2 (uk) 2001-08-15
JP4486055B2 (ja) 2010-06-23
DK0587805T3 (de) 1997-03-17
GR3022138T3 (en) 1997-03-31
HU9303470D0 (en) 1994-04-28
NL9100989A (nl) 1993-01-04
SK137593A3 (en) 1994-09-07
HUT69602A (en) 1995-09-28
FI110060B (fi) 2002-11-29
DK0587805T4 (da) 2004-12-20
DE69214146T3 (de) 2005-05-04
NO934431L (no) 1994-02-07
WO1992021751A1 (en) 1992-12-10
US5789177A (en) 1998-08-04
CZ283283B6 (cs) 1998-02-18

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