EP0598759A4 - Rekombinanter infektiöser rinder rhinotracheitis virus. - Google Patents

Rekombinanter infektiöser rinder rhinotracheitis virus.

Info

Publication number
EP0598759A4
EP0598759A4 EP92916108A EP92916108A EP0598759A4 EP 0598759 A4 EP0598759 A4 EP 0598759A4 EP 92916108 A EP92916108 A EP 92916108A EP 92916108 A EP92916108 A EP 92916108A EP 0598759 A4 EP0598759 A4 EP 0598759A4
Authority
EP
European Patent Office
Prior art keywords
rhinotracheitis virus
infectious bovine
bovine rhinotracheitis
recombinant infectious
recombinant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP92916108A
Other languages
English (en)
French (fr)
Other versions
EP0598759A1 (de
Inventor
Mark D Cochran
Richard D Macdonald
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntro Corp
Original Assignee
Syntro Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntro Corp filed Critical Syntro Corp
Publication of EP0598759A1 publication Critical patent/EP0598759A1/de
Publication of EP0598759A4 publication Critical patent/EP0598759A4/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16722New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/16011Herpesviridae
    • C12N2710/16711Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16741Use of virus, viral particle or viral elements as a vector
    • C12N2710/16743Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011Details
    • C12N2720/12011Reoviridae
    • C12N2720/12311Rotavirus, e.g. rotavirus A
    • C12N2720/12322New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/18011Paramyxoviridae
    • C12N2760/18611Respirovirus, e.g. Bovine, human parainfluenza 1,3
    • C12N2760/18622New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Farming Of Fish And Shellfish (AREA)
EP92916108A 1991-07-18 1992-07-20 Rekombinanter infektiöser rinder rhinotracheitis virus. Withdrawn EP0598759A4 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US73258491A 1991-07-18 1991-07-18
US732584 1991-07-18
PCT/US1992/006034 WO1993002104A1 (en) 1991-07-18 1992-07-20 Recombinant infectious bovine rhinotracheitis virus

Publications (2)

Publication Number Publication Date
EP0598759A1 EP0598759A1 (de) 1994-06-01
EP0598759A4 true EP0598759A4 (de) 1998-06-03

Family

ID=24944128

Family Applications (1)

Application Number Title Priority Date Filing Date
EP92916108A Withdrawn EP0598759A4 (de) 1991-07-18 1992-07-20 Rekombinanter infektiöser rinder rhinotracheitis virus.

Country Status (4)

Country Link
EP (1) EP0598759A4 (de)
AU (1) AU672583B2 (de)
CA (1) CA2113641A1 (de)
WO (1) WO1993002104A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5783195A (en) * 1991-07-18 1998-07-21 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus S-IBR-052 and uses thereof
US6410033B1 (en) 1987-07-27 2002-06-25 Syntro Corporation Recombinant infectious bovine rhinotracheitis virus
FR2693472B1 (fr) * 1992-06-26 1994-12-23 Rhone Merieux Mutants du virus de la rhinotrachéite infectieuse bovine, délétés dans l'un des gènes des glycoprotéines mineures, vaccins préparés à partir de ces souches, méthodes de production et méthodes d'utilisation.
WO1994024296A2 (en) * 1993-04-19 1994-10-27 University Of Saskatchewan Recombinant bovine herpesvirus type 1 vaccines
EP0663403A1 (de) * 1993-11-23 1995-07-19 Akzo Nobel N.V. Impfstoffe von Boviner Herpesviren Typ I
CA2136381A1 (en) * 1993-11-23 1995-05-24 Gunther Keil Vector vaccines of bovine herpesvirus 1
ES2074965B1 (es) * 1994-01-31 1996-05-01 Hipra Lab Sa Virus mutante recombinante de rinotraqueitis infecciosa bovina y vacunas que lo contienen.
US6284251B1 (en) 1996-02-26 2001-09-04 Kansas State University Research Foundation BHV-1 gene-deleted virus vaccine

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987004463A1 (en) * 1986-01-27 1987-07-30 Syntro Corporation Attenuated herpesviruses, herpesviruses which include foreign dna encoding an amino acid sequence and vaccine containing same
WO1989001040A1 (en) * 1987-07-27 1989-02-09 Syntro Corporation Attenuated herpes viruses, herpes viruses which include foreign dna encoding an amino acid sequence and vaccines containing same
EP0316658A1 (de) * 1987-11-03 1989-05-24 Novagene, Inc. Mutanten des infektiösen bovinen Rhinotracheitisvirus, Vakzine die sie enthalten, Verfahren zu ihrer Herstellung und ihrer Verwendung
EP0326127A2 (de) * 1988-01-26 1989-08-02 Novagene, Inc. Infektiöse Rinder-Rhinotracheitis-Virus-Insertionsmutanten, sie enthaltende Impfstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung
EP0471457A2 (de) * 1990-07-24 1992-02-19 Novagene, Inc. Herpesvirus-Vektor, der ein Epitope des Maul- und Klauenseuchenviruses exprimiert
WO1992021751A1 (en) * 1991-06-07 1992-12-10 Stichting Centraal Diergeneeskundig Instituut Bovine herpesvirus type 1 deletion mutants, vaccines based thereon, diagnostic kits for detection of bovine herpesvirus type 1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4132775A (en) * 1973-12-03 1979-01-02 Richardson-Merrell Inc. Infectious bovine rhinotracheitis virus vaccine and method of preparing and using the same
CA1339735C (en) * 1984-04-27 1998-03-17 Ian Hamilton Holmes. Cloning and sequencing of the major outer capsid gylcoprotein gene of a human rotavirus
DE3677494D1 (de) * 1985-07-29 1991-03-14 Upjohn Co Virus-impfstoff.
US4877737A (en) * 1985-09-06 1989-10-31 Prutech Research And Development Partnership Attenuated pseudorabies virus which has a deletion in at least a portion of a repeat sequence and vaccine containing same
US4703011A (en) * 1985-11-12 1987-10-27 Novagene, Inc. Thymidine kinase deletion mutants of bovine herpesvirus-1

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987004463A1 (en) * 1986-01-27 1987-07-30 Syntro Corporation Attenuated herpesviruses, herpesviruses which include foreign dna encoding an amino acid sequence and vaccine containing same
WO1989001040A1 (en) * 1987-07-27 1989-02-09 Syntro Corporation Attenuated herpes viruses, herpes viruses which include foreign dna encoding an amino acid sequence and vaccines containing same
EP0316658A1 (de) * 1987-11-03 1989-05-24 Novagene, Inc. Mutanten des infektiösen bovinen Rhinotracheitisvirus, Vakzine die sie enthalten, Verfahren zu ihrer Herstellung und ihrer Verwendung
EP0326127A2 (de) * 1988-01-26 1989-08-02 Novagene, Inc. Infektiöse Rinder-Rhinotracheitis-Virus-Insertionsmutanten, sie enthaltende Impfstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung
EP0471457A2 (de) * 1990-07-24 1992-02-19 Novagene, Inc. Herpesvirus-Vektor, der ein Epitope des Maul- und Klauenseuchenviruses exprimiert
WO1992021751A1 (en) * 1991-06-07 1992-12-10 Stichting Centraal Diergeneeskundig Instituut Bovine herpesvirus type 1 deletion mutants, vaccines based thereon, diagnostic kits for detection of bovine herpesvirus type 1

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KIT S ET AL: "Exprssion of pseudorabies virus and foot-and -mouth disease virus proteins by modified-live infectious bovine rhinotracheitis virus vectors", PROCEEDING OF THE 94TH ANNUAL MEETING OF THE UNITED STATES ANIMAL HEALTH ASSOCIATION, 1990, US, pages 66 - 75, XP002060268 *
LONGNECKER R ET AL: "Clustering of genes dispensable for growth in culture in the S component of the HSV-1 genome", SCIENCE, vol. 236, 1987, LANCASTER, PA US, pages 573 - 576, XP002034507 *
MCGEOCH D: "Evolutionary relationships of virion glycoprotein genes in the S regions of alphaherpesvirus genomes", JOURNAL OF GENERAL VIROLOGY, vol. 71, 1990, READING GB, pages 2361 - 2367, XP002034509 *
See also references of WO9302104A1 *
WEBER PC ET AL: "Rapid identification of nonessential genes of herpes simplex virus type 1 by Tn5 mutagenesis", SCIENCE, vol. 236, 1987, LANCASTER, PA US, pages 576 - 579, XP002034508 *

Also Published As

Publication number Publication date
EP0598759A1 (de) 1994-06-01
CA2113641A1 (en) 1993-02-04
WO1993002104A1 (en) 1993-02-04
AU2393292A (en) 1993-02-23
AU672583B2 (en) 1996-10-10

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