ATE140956T1 - Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium - Google Patents

Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium

Info

Publication number
ATE140956T1
ATE140956T1 AT90905151T AT90905151T ATE140956T1 AT E140956 T1 ATE140956 T1 AT E140956T1 AT 90905151 T AT90905151 T AT 90905151T AT 90905151 T AT90905151 T AT 90905151T AT E140956 T1 ATE140956 T1 AT E140956T1
Authority
AT
Austria
Prior art keywords
culture
cell number
compartment
sub
cell mass
Prior art date
Application number
AT90905151T
Other languages
English (en)
Inventor
Van Taiariol
Robert V Oakley
Peter Ventura
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int filed Critical Baxter Int
Application granted granted Critical
Publication of ATE140956T1 publication Critical patent/ATE140956T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/34Internal compartments or partitions
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/14Bags
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/24Gas permeable parts

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
AT90905151T 1989-03-10 1990-03-09 Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium ATE140956T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/321,765 US5017490A (en) 1989-03-10 1989-03-10 Method for in vitro reproduction and growth of cells in culture medium

Publications (1)

Publication Number Publication Date
ATE140956T1 true ATE140956T1 (de) 1996-08-15

Family

ID=23251935

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90905151T ATE140956T1 (de) 1989-03-10 1990-03-09 Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium

Country Status (9)

Country Link
US (1) US5017490A (de)
EP (1) EP0418354B1 (de)
JP (1) JP2981684B2 (de)
AT (1) ATE140956T1 (de)
CA (1) CA2011917C (de)
DE (1) DE69027962T2 (de)
DK (1) DK0418354T3 (de)
ES (1) ES2092506T3 (de)
WO (1) WO1990010690A1 (de)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4027126C1 (de) * 1990-08-28 1991-12-12 Eberhard Prof. Dr. 2000 Hamburg De Bock
ATE138256T1 (de) * 1990-10-31 1996-06-15 Baxter Int Vaskularisation erlaubendes implantatmaterial
US5330915A (en) * 1991-10-18 1994-07-19 Endotronics, Inc. Pressure control system for a bioreactor
IL102189A (en) * 1992-06-12 1995-07-31 Univ Ben Gurion Device for growing microorganisms
DE4303936C1 (de) * 1993-02-10 1994-08-18 Gore W L & Ass Gmbh Vorrichtung zur Entfernung von gasförmigen Stoffen aus einem Gasstrom
DE69433970T2 (de) * 1993-08-10 2005-08-11 W.L. Gore & Associates, Inc., Newark Zelleinkapselungsvorrichtung
JPH0780041A (ja) * 1993-09-20 1995-03-28 Terumo Corp 細胞保存バッグシステム
US5935847A (en) 1994-10-28 1999-08-10 Baxter International Inc. Multilayer gas-permeable container for the culture of adherent and non-adherent cells
US6297046B1 (en) 1994-10-28 2001-10-02 Baxter International Inc. Multilayer gas-permeable container for the culture of adherent and non-adherent cells
US5728581A (en) * 1995-06-07 1998-03-17 Systemix, Inc. Method of expanding hematopoietic stem cells, reagents and bioreactors for use therein
US6024220A (en) 1995-06-07 2000-02-15 Baxter International Inc. Encapsulated seam for multilayer materials
US6391404B1 (en) 1995-06-07 2002-05-21 Baxter International Inc. Coextruded multilayer film materials and containers made therefrom
AU6854696A (en) * 1995-09-22 1997-04-09 Gore Hybrid Technologies, Inc. Improved cell encapsulation device
US5964261A (en) 1996-05-29 1999-10-12 Baxter International Inc. Implantation assembly
DE19707497A1 (de) * 1996-08-16 1998-02-19 Boehringer Mannheim Gmbh Reaktionsbeutelvorrichtung zur Durchführung von mehrstufigen Kultivierungs/Separations-Vorgängen und/oder Reaktionen
DK1060241T4 (da) 1997-12-24 2011-01-24 Solvay Biologicals Bv Frembringelse af celler til fremstilling af biologiske materialer
US6183460B1 (en) 1998-01-22 2001-02-06 Baxter International Inc. Multi-use solution container having flaps
US7326564B2 (en) 2001-02-20 2008-02-05 St. Jude Medical, Inc. Flow system for medical device evaluation and production
EP1696024B1 (de) * 2003-12-18 2015-03-04 Kaneka Corporation Vorrichtung zur zellkultur
CA2557574C (en) * 2004-02-23 2013-04-30 Eudes Francois Marie De Crecy Continuous culture apparatus with mobile vessel, allowing selection of fitter cell variants
EP1739165A1 (de) * 2005-06-29 2007-01-03 Cellution Biotech B.V. Verfahren und Vorrichtung zur Kultivierung von Zellen unter Verwendung von Wellenbewegung
US7745209B2 (en) 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
US20080131959A1 (en) * 2006-11-15 2008-06-05 Millipore Corporation Bioreactor construction
US20080131960A1 (en) * 2006-11-15 2008-06-05 Millipore Corporation Self standing bioreactor construction
AU2007332869B2 (en) 2006-12-07 2012-10-11 Wilson Wolf Manufacturing, LLC Highly efficient gas permeable devices and methods for culturing cells
CN101541946B (zh) * 2007-01-22 2013-08-14 伊恩·梅尔康·莱特 体积可变化的生物反应器
JP5023795B2 (ja) 2007-04-27 2012-09-12 東洋製罐株式会社 細胞培養方法、細胞培養システム、及び培地調整装置
EP2141225B1 (de) * 2007-04-27 2020-10-21 Toyo Seikan Kaisha, Ltd. Zellkulturvorrichtung, zellkultursystem und zellkulturverfahren
US8114664B2 (en) * 2007-07-12 2012-02-14 Worcester Polytechnic Institute Scalable wall bioreactor for culture of plant and animal tissues
US8367400B2 (en) * 2008-03-21 2013-02-05 Corning Incorporated Culture vessel allowing large in situ scale up
WO2009123173A1 (ja) * 2008-04-01 2009-10-08 東洋製罐株式会社 培養容器、培養方法、及び培養装置
JP5309658B2 (ja) * 2008-04-01 2013-10-09 東洋製罐グループホールディングス株式会社 培養方法、及び培養装置
JP5309657B2 (ja) * 2008-04-01 2013-10-09 東洋製罐グループホールディングス株式会社 培養容器
US20100055764A1 (en) * 2008-08-27 2010-03-04 Martin Gregory R Cell culture apparatus and method
WO2010096545A2 (en) * 2009-02-18 2010-08-26 Biolex Thepapeutids, Inc. Aseptic bioreactor system for processing biological materials
US20100279354A1 (en) * 2009-04-29 2010-11-04 Evolugate, Llc Adapting microorganisms for agricultural products
JP5740841B2 (ja) * 2010-05-19 2015-07-01 東洋製罐グループホールディングス株式会社 細胞培養方法、細胞培養装置、及び細胞培養装置の制御方法
DE102014202261A1 (de) * 2014-02-07 2015-08-27 Eurozyto Gmbh Behältnis und Set zur Bereitstellung parenteraler Nahrung
JP6405690B2 (ja) * 2014-05-09 2018-10-17 東洋製罐グループホールディングス株式会社 複室培養容器、及び細胞培養方法
US10731118B2 (en) 2014-05-28 2020-08-04 Ge Healthcare Bio-Sciences Corp. Bag assembly for cultivation of cells
JP6738058B2 (ja) * 2014-05-28 2020-08-12 サイティバ・スウェーデン・アクチボラグ 細胞培養用バッグアセンブリ
US10731122B2 (en) 2015-01-30 2020-08-04 Toyo Seikan Group Holdings, Ltd. Cell culture method and cell culture apparatus
EP3253863B1 (de) * 2015-02-05 2019-07-10 General Electric Company Bioreaktorsystem zur zellkultivierung
EP3656845A1 (de) * 2015-03-20 2020-05-27 Sekisui Chemical Co., Ltd. Mikroorganismuskultivierungsverfahren und kultivierungsvorrichtung
JP7026990B2 (ja) * 2016-07-05 2022-03-01 グローバル・ライフ・サイエンシズ・ソリューションズ・ユーエスエー・エルエルシー 調節容積式の細胞培養のための装置および方法
WO2019166998A1 (en) * 2018-03-02 2019-09-06 Thermo Electron Led Gmbh Single-use centrifuge containers for separating biological suspensions and methods of use
EP3650528A1 (de) 2018-11-08 2020-05-13 Aglaris Ltd Zellkultursystem und -verfahren
JP2022099262A (ja) * 2020-12-22 2022-07-04 アイ ピース,インコーポレイテッド 細胞の培養器及び細胞の培養方法
CA3221418A1 (en) * 2021-06-07 2022-12-15 Geoffrey L. Hodge Cell culture vessel for use in manufacturing cell products
GB2617629B (en) * 2022-06-29 2024-04-10 Hoxton Farms Ltd System for cell culture

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1792450A (en) 1927-10-24 1931-02-10 Stich Eugen Process and appliance for fermenting sacchariferous liquids
US3102082A (en) * 1961-07-17 1963-08-27 John H Brewer Apparatus and method for culturing micro-organisms
US3257072A (en) * 1963-01-07 1966-06-21 Cryogenic Eng Co Whole blood storage structure
US3814395A (en) * 1964-02-27 1974-06-04 Kaelin J R Aeration plant for clarifying sewage and waste effluents
US3911918A (en) * 1972-04-13 1975-10-14 Ralph D Turner Blood collection, storage and administering bag
US3946780A (en) * 1973-01-04 1976-03-30 Sellers John C Fermentation container
US4132594A (en) * 1976-06-28 1979-01-02 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Gas diffusion liquid storage bag and method of use for storing blood
US4059486A (en) * 1976-11-03 1977-11-22 Monsanto Company Cell culture process
IT1122151B (it) * 1978-07-26 1986-04-23 Biotest Serum Institut Gmbh Sistema di sacchetti per la coltura di sangue
CS231615B1 (en) * 1981-12-29 1984-12-14 Vladislav Vlcek Method of cultivation of cells of higher organism and device to perform the method
US4507114A (en) * 1983-10-21 1985-03-26 Baxter Travenol Laboratories, Inc. Multiple chamber container having leak detection compartment
US4632244A (en) * 1986-02-19 1986-12-30 Boris Landau Multiple chamber flexible container
US4829002A (en) * 1986-05-12 1989-05-09 Baxter International Inc. System for metering nutrient media to cell culture containers and method
US4734373A (en) * 1986-06-24 1988-03-29 Bartal Arie H Apparatus for enhancing cell growth, preservation and transport
US4717668A (en) * 1986-12-12 1988-01-05 Baxter Travenol Laboratories, Inc. Plastic roller bottle for suspension cultures

Also Published As

Publication number Publication date
US5017490A (en) 1991-05-21
EP0418354A4 (en) 1991-12-27
WO1990010690A1 (en) 1990-09-20
DE69027962D1 (de) 1996-09-05
JPH03505164A (ja) 1991-11-14
EP0418354B1 (de) 1996-07-31
EP0418354A1 (de) 1991-03-27
JP2981684B2 (ja) 1999-11-22
ES2092506T3 (es) 1996-12-01
CA2011917C (en) 2000-01-25
DK0418354T3 (da) 1996-08-26
DE69027962T2 (de) 1997-01-02
CA2011917A1 (en) 1990-09-10

Similar Documents

Publication Publication Date Title
ATE140956T1 (de) Vorrichtung und verfahren zur vermehrung in vivo und zellzucht in einem kulturmedium
DE69637656D1 (de) Methoden zur Züchtung von Tierzellen
ATE419332T1 (de) Verfahren zur zellkultivierung in einer monoschicht
ES8609459A1 (es) Procedimiento para la preparacion de pelicula de celulosa
ES2150938T3 (es) Produccion mejorada de taxol y taxanos mediante cultivos celulares de especies de taxus.
ATE204322T1 (de) Vorrichtung und verfahren zum aufbewahren und zur züchtung biologischer zellen
ATE37764T1 (de) Verfahren zur vermehrung von pflanzlichen gewebekulturen.
ATE138684T1 (de) Verfahren zur erzeugung von zellmasse und/oder fermentierungsprodukten unter sterilen bedingungen sowie vorrichtung zur durchführung des verfahrens
ATE46358T1 (de) Verfahren zur zuechtung von lyophilisierten mikroorganismen.
ATE67787T1 (de) Verfahren zur herstellung von proteinen mittels induzierbarer expressionssysteme in in-vivovermehrten, genetisch modifizierten eukaryotischen wirtszellen.
EP0380692A4 (en) Plant tissue culture process
RU96106889A (ru) Способ получения селенсодержащего препарата биомассы спирулины
EP0340783A3 (en) Apparatus for culturing animal cells, method of culturing thereof and diagnostics of the culture
DE3677217D1 (de) Verfahren zum regenerieren von mais.
CH611774A5 (en) Process for the culture of cells of higher plants on lactose-containing media
ATE76251T1 (de) Verfahren zur kultur von pflanzengewebe.
FR2614498B1 (fr) Procede de culture de champignons, sur compost supplemente par un apport proteique et un apport enzymatique
ATE12646T1 (de) Antibiotikum am-5344-a2 und verfahren zu dessen herstellung.
DE69004714D1 (de) Verfahren zur Zucht von Pilzen und Substrat zur Durchführung dieses Verfahrens.
EP0299067A4 (de) Zuchtmedium für pflanzen.
UA10728A (uk) Спосіб розмhожеhhя hапівкарликових підщепів яблуhі в культурі ткаhиhи
ATE115183T1 (de) Zellzüchtungsverfahren.
SE7707467L (sv) Forfarande for framstellning av en antibiotisk substans
KR940000572A (ko) 사람 인터루킨- 6 단백질을 생산하는 식물 및 그의 제조방법
GB1449584A (en) Process for the accelerated propagation of strawberry plants by -micropropagation in vitro- and the plantlets obtained

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee