ATE132486T1 - Pyrrolidin-dionderivate - Google Patents

Pyrrolidin-dionderivate

Info

Publication number
ATE132486T1
ATE132486T1 AT91917487T AT91917487T ATE132486T1 AT E132486 T1 ATE132486 T1 AT E132486T1 AT 91917487 T AT91917487 T AT 91917487T AT 91917487 T AT91917487 T AT 91917487T AT E132486 T1 ATE132486 T1 AT E132486T1
Authority
AT
Austria
Prior art keywords
pyrrolidine
dione derivatives
treatment
relates
compounds
Prior art date
Application number
AT91917487T
Other languages
English (en)
Inventor
Banavara L Mylari
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of ATE132486T1 publication Critical patent/ATE132486T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
AT91917487T 1990-10-15 1991-09-13 Pyrrolidin-dionderivate ATE132486T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59761490A 1990-10-15 1990-10-15

Publications (1)

Publication Number Publication Date
ATE132486T1 true ATE132486T1 (de) 1996-01-15

Family

ID=24392236

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91917487T ATE132486T1 (de) 1990-10-15 1991-09-13 Pyrrolidin-dionderivate

Country Status (12)

Country Link
EP (1) EP0553130B1 (de)
JP (1) JPH0692367B2 (de)
AT (1) ATE132486T1 (de)
CA (1) CA2091566A1 (de)
DE (1) DE69116162T2 (de)
DK (1) DK0553130T3 (de)
ES (1) ES2082232T3 (de)
FI (1) FI931666A0 (de)
GR (1) GR3018920T3 (de)
IE (1) IE913554A1 (de)
PT (1) PT99224A (de)
WO (1) WO1992006954A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL124557A0 (en) * 1995-12-15 1998-12-06 Novo Nordisk As Compositions for reducing blood glucose and/or inhibiting the activity of cgrp
MXPA02012596A (es) * 2000-06-21 2003-04-10 Hoffmann La Roche Derivados de benzotiazol.
JP4338192B2 (ja) 2001-08-10 2009-10-07 塩野義製薬株式会社 抗ウイルス剤
CN104001078A (zh) * 2014-06-05 2014-08-27 青岛市城阳区人民医院 一种治疗糖尿病肾病的中药药剂及制备方法
CN107892666B (zh) * 2017-12-12 2021-10-15 吉林医药学院 一种5-苯基吡咯衍生物及其制备方法和用途

Also Published As

Publication number Publication date
WO1992006954A2 (en) 1992-04-30
CA2091566A1 (en) 1992-04-16
JPH0692367B2 (ja) 1994-11-16
JPH05507284A (ja) 1993-10-21
FI931666A (fi) 1993-04-14
DK0553130T3 (da) 1996-02-05
DE69116162T2 (de) 1996-05-02
EP0553130A1 (de) 1993-08-04
DE69116162D1 (de) 1996-02-15
IE913554A1 (en) 1992-04-22
ES2082232T3 (es) 1996-03-16
EP0553130B1 (de) 1996-01-03
FI931666A0 (fi) 1993-04-14
PT99224A (pt) 1992-09-30
WO1992006954A3 (en) 1992-08-06
GR3018920T3 (en) 1996-05-31

Similar Documents

Publication Publication Date Title
DE69413542T2 (de) Perhydroisoindolderivate als substanz p antagonisten
IL116122A0 (en) Intermediates to heterocyclic-cyclic amine derivatives
TR199902626T2 (xx) Enflamasyon tedavisi i�in ikameli benzopiran t�revleri.
FI101376B1 (fi) Menetelmä 3-bentsyyliamino-2-fenyylipiperidiinijohdannaisten valmistamiseksi
SE8600174D0 (sv) Nytt forfarande for framstellning av n-(2-pyrimidinyl)-piperazinylalkylazaspiroalkandioner
ATE159250T1 (de) Neue pyrazinderivative, ihre herstellung und verwendung
ATE244222T1 (de) N-substituierte azabicycloheptan-derivate und ihre verwendung, z.b., als neuroleptika
ATE132486T1 (de) Pyrrolidin-dionderivate
ATE223376T1 (de) Bisarylcyclobutenderivate als cyclooxygenasehemmer
DE59109225D1 (de) Verwendung von pyridylmethylsulfinyl-1h-benzimidazol derivaten zur behandlung durch helicobacter verursachter erkrankungen
ES2104174T3 (es) Derivados de bencilamino, bencilamido y bencilimido ciclicos utilizados como agentes antipsicoticos.
FI20021652A (fi) Tratsodonin alkyylijohdannaisten valmistuksessa käyttökelpoisia välituotteita
ATE218138T1 (de) N-substituierte azabicycloheptan-derivate, ihre herstellung und verwendung
AU664093B2 (en) Arylpiperidine and arylpiperazine alkylbenzyl alcohol derivatives as antipsychotics
HU9600300D0 (en) Thiocarbamoyl derivatives using as antimicrobial agents and process for producing of these
ATE263139T1 (de) 3-alkoxylbenzylaminderivate und ihre verwendung als arzneimittel zur behandlung von schizophrenie
ATE239015T1 (de) N-substituierte azabicycloheptan-derivate, ihre herstellung und verwendung
FI944076A (fi) Menetelmä terapeuttisesti käytt¦kelpoisten N-(3-hydroksi-4-piperidinyyli)(dihydrobentsofuraani-, dihydro-2H-bentsopyraani- tai dihydrobentsodioksiini)karboksamidijohdannaisten valmistamiseksi ja välituote

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee