ATE131483T1 - Verfahren zur herstellung von penemen - Google Patents
Verfahren zur herstellung von penemenInfo
- Publication number
- ATE131483T1 ATE131483T1 AT90112654T AT90112654T ATE131483T1 AT E131483 T1 ATE131483 T1 AT E131483T1 AT 90112654 T AT90112654 T AT 90112654T AT 90112654 T AT90112654 T AT 90112654T AT E131483 T1 ATE131483 T1 AT E131483T1
- Authority
- AT
- Austria
- Prior art keywords
- compound
- formula
- chem
- defined above
- formula iii
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 11
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 5
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 125000006239 protecting group Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 150000007529 inorganic bases Chemical class 0.000 abstract 1
- 150000007530 organic bases Chemical class 0.000 abstract 1
- -1 oxalyl halide Chemical class 0.000 abstract 1
- 239000002516 radical scavenger Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/32—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D317/34—Oxygen atoms
- C07D317/40—Vinylene carbonate; Substituted vinylene carbonates
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cephalosporin Compounds (AREA)
- Electric Double-Layer Capacitors Or The Like (AREA)
- Crystals, And After-Treatments Of Crystals (AREA)
- Glass Compositions (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Medicinal Preparation (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Pens And Brushes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898915392A GB8915392D0 (en) | 1989-07-05 | 1989-07-05 | Process for penems |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE131483T1 true ATE131483T1 (de) | 1995-12-15 |
Family
ID=10659566
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT90112654T ATE131483T1 (de) | 1989-07-05 | 1990-07-03 | Verfahren zur herstellung von penemen |
Country Status (21)
| Country | Link |
|---|---|
| EP (2) | EP0433425A1 (de) |
| JP (1) | JPH05500210A (de) |
| KR (1) | KR920701212A (de) |
| AT (1) | ATE131483T1 (de) |
| AU (1) | AU644805B2 (de) |
| CA (1) | CA2035434A1 (de) |
| DD (1) | DD299304A5 (de) |
| DE (1) | DE69024114T2 (de) |
| DK (1) | DK0406790T3 (de) |
| ES (1) | ES2083401T3 (de) |
| FI (1) | FI911081A7 (de) |
| GB (1) | GB8915392D0 (de) |
| HU (1) | HU209924B (de) |
| IE (1) | IE902423A1 (de) |
| IL (1) | IL94943A (de) |
| MY (1) | MY105720A (de) |
| NZ (1) | NZ234329A (de) |
| PT (1) | PT94589A (de) |
| RU (1) | RU2049786C1 (de) |
| WO (1) | WO1991000283A1 (de) |
| ZA (1) | ZA905198B (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8818789D0 (en) * | 1988-08-08 | 1988-09-07 | Erba Carlo Spa | Crystalline(5r 6s)-2-carbamoyloxymethyl-6-((1r)-hydroxyethyl)-2-penem-carboxylic acid & pharmaceutical formulation |
| GB9006114D0 (en) * | 1990-03-19 | 1990-05-16 | Erba Carlo Spa | Process for preparing penem esters |
| IT1286558B1 (it) * | 1996-02-27 | 1998-07-15 | Menarini Farma Ind | Processo per la preparazione di 2-alogenometil-penems e loro uso per la preparazione di penems antibatterici |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5835190A (ja) * | 1981-08-25 | 1983-03-01 | Sankyo Co Ltd | ペネム−３−カルボン酸誘導体 |
| JPS59212488A (ja) * | 1983-05-18 | 1984-12-01 | Kyoto Yakuhin Kogyo Kk | ジオキソ−ル誘導体 |
| JPH075463B2 (ja) * | 1985-03-09 | 1995-01-25 | サントリー株式会社 | 抗菌剤 |
| GB8713515D0 (en) * | 1987-06-10 | 1987-07-15 | Erba Farmitalia | Methoxymethyl compounds |
| GB8716679D0 (en) * | 1987-07-15 | 1987-08-19 | Erba Farmitalia | Penem derivatives |
-
1989
- 1989-07-05 GB GB898915392A patent/GB8915392D0/en active Pending
-
1990
- 1990-07-02 IL IL9494390A patent/IL94943A/en not_active IP Right Cessation
- 1990-07-02 NZ NZ234329A patent/NZ234329A/en unknown
- 1990-07-03 ZA ZA905198A patent/ZA905198B/xx unknown
- 1990-07-03 EP EP90910622A patent/EP0433425A1/de active Pending
- 1990-07-03 KR KR1019910700246A patent/KR920701212A/ko not_active Ceased
- 1990-07-03 EP EP90112654A patent/EP0406790B1/de not_active Expired - Lifetime
- 1990-07-03 DE DE69024114T patent/DE69024114T2/de not_active Expired - Fee Related
- 1990-07-03 HU HU905471A patent/HU209924B/hu not_active IP Right Cessation
- 1990-07-03 FI FI911081A patent/FI911081A7/fi not_active Application Discontinuation
- 1990-07-03 AT AT90112654T patent/ATE131483T1/de active
- 1990-07-03 RU SU904894934A patent/RU2049786C1/ru active
- 1990-07-03 AU AU60318/90A patent/AU644805B2/en not_active Ceased
- 1990-07-03 CA CA002035434A patent/CA2035434A1/en not_active Abandoned
- 1990-07-03 ES ES90112654T patent/ES2083401T3/es not_active Expired - Lifetime
- 1990-07-03 DK DK90112654.0T patent/DK0406790T3/da active
- 1990-07-03 JP JP2510197A patent/JPH05500210A/ja active Pending
- 1990-07-03 WO PCT/EP1990/001060 patent/WO1991000283A1/en not_active Ceased
- 1990-07-04 PT PT94589A patent/PT94589A/pt not_active Application Discontinuation
- 1990-07-04 IE IE242390A patent/IE902423A1/en unknown
- 1990-07-05 MY MYPI90001127A patent/MY105720A/en unknown
- 1990-10-02 DD DD90344385A patent/DD299304A5/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2049786C1 (ru) | 1995-12-10 |
| AU6031890A (en) | 1991-01-17 |
| ES2083401T3 (es) | 1996-04-16 |
| HUT56374A (en) | 1991-08-28 |
| JPH05500210A (ja) | 1993-01-21 |
| DD299304A5 (de) | 1992-04-09 |
| HU209924B (en) | 1994-12-28 |
| AU644805B2 (en) | 1993-12-23 |
| MY105720A (en) | 1994-11-30 |
| IL94943A0 (en) | 1991-06-10 |
| IL94943A (en) | 1994-11-11 |
| PT94589A (pt) | 1991-03-20 |
| GB8915392D0 (en) | 1989-08-23 |
| IE902423A1 (en) | 1991-06-19 |
| FI911081A0 (fi) | 1991-03-04 |
| KR920701212A (ko) | 1992-08-11 |
| CA2035434A1 (en) | 1991-01-06 |
| FI911081A7 (fi) | 1991-03-04 |
| DE69024114D1 (de) | 1996-01-25 |
| DE69024114T2 (de) | 1996-05-09 |
| DK0406790T3 (da) | 1996-01-29 |
| NZ234329A (en) | 1992-03-26 |
| EP0433425A1 (de) | 1991-06-26 |
| EP0406790B1 (de) | 1995-12-13 |
| WO1991000283A1 (en) | 1991-01-10 |
| EP0406790A1 (de) | 1991-01-09 |
| ZA905198B (en) | 1991-04-24 |
| HU905471D0 (en) | 1991-06-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE127809T1 (de) | Verfahren zur herstellung von verbindungen zur behandlung der gutartigen prostatahypertrophie. | |
| DE3778135D1 (de) | Verfahren zur herstellung von (+)-biotin. | |
| ATE157647T1 (de) | Verfahren zur herstellung von alpha- ketoamidderivaten | |
| ATE156134T1 (de) | Verfahren zur herstellung von alkylpolyglukosiden | |
| ATE154348T1 (de) | Verfahren zur herstellung von 1,5-benzothiazepin- derivaten | |
| ATE131483T1 (de) | Verfahren zur herstellung von penemen | |
| DK141786D0 (da) | Fremgangsmaade til fremstilling af et mellemprodukt til brug ved fremstilling af 1-beta-methylcarbapenemantibiotika | |
| ATE384067T1 (de) | Verfahren zur herstellung von 3-cephemderivaten | |
| DE3767618D1 (de) | Verfahren zur herstellung von tetrafluorphthalsaeure. | |
| DE69714749D1 (de) | Verfahren zur herstellung von 3-amino-2-hydroxy-1-propylethern | |
| ATE251135T1 (de) | Verfahren zur herstellung von 1-substituierten pyrrol-3-carbonsäure-derivaten | |
| ATE189453T1 (de) | Verfahren zur herstellung von 2-cyanobiphenyl- verbindungen | |
| ATE129231T1 (de) | Verfahren zur herstellung von optisch aktiven norbornylaminderivaten. | |
| ATE299498T1 (de) | Verfahren zur herstellung von imidazolderivaten | |
| SE8503811L (sv) | Nytt forfarande for framstellning av en aminolakton | |
| ATE245136T1 (de) | Verfahren zum herstellen eines tert-alkylesters einer carbonsäure | |
| ATE25680T1 (de) | Verfahren zur herstellung von 4-amino-5-dialkoxy- methylpyrimidinderivaten. | |
| ATE157357T1 (de) | Verfahren zur herstellung von dihydrofuranonderivaten | |
| ATE234806T1 (de) | Verfahren zur herstellung von 2-alkyliden-4- bromacetessigsäureestern | |
| ATE205497T1 (de) | Verfahren zur herstellung von 3-norcephem- verbindungen | |
| ATE244228T1 (de) | Verfahren zur herstellung von chloroacetylaminothiazoleaceticsäure derivate | |
| ATE242252T1 (de) | Verfahren zur herstellung von 2-isocephem- derivaten | |
| DE69520566D1 (de) | Verfahren zur herstellung eines carbonsäurederivates | |
| ATE167474T1 (de) | Verfahren zur herstellung von n-alkylpyrazolen | |
| ATE161825T1 (de) | Verfahren zur herstellung von alpha-alkoxy- iminophenylacetonitril |