ATE130866T1 - Statischer oxygenator zur suspensionskultur von tierischen zellen. - Google Patents
Statischer oxygenator zur suspensionskultur von tierischen zellen.Info
- Publication number
- ATE130866T1 ATE130866T1 AT90904984T AT90904984T ATE130866T1 AT E130866 T1 ATE130866 T1 AT E130866T1 AT 90904984 T AT90904984 T AT 90904984T AT 90904984 T AT90904984 T AT 90904984T AT E130866 T1 ATE130866 T1 AT E130866T1
- Authority
- AT
- Austria
- Prior art keywords
- liquid
- oxygenator
- static
- animal cells
- gas
- Prior art date
Links
- 230000003068 static effect Effects 0.000 title abstract 2
- 238000004114 suspension culture Methods 0.000 title abstract 2
- 239000007788 liquid Substances 0.000 abstract 5
- 238000007872 degassing Methods 0.000 abstract 2
- 239000011148 porous material Substances 0.000 abstract 2
- 210000004102 animal cell Anatomy 0.000 abstract 1
- 239000001963 growth medium Substances 0.000 abstract 1
- 238000009630 liquid culture Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 230000001706 oxygenating effect Effects 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/2366—Parts; Accessories
- B01F23/2368—Mixing receptacles, e.g. tanks, vessels or reactors, being completely closed, e.g. hermetically closed
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/24—Gas permeable parts
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/231—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids by bubbling
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/231—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids by bubbling
- B01F23/23105—Arrangement or manipulation of the gas bubbling devices
- B01F23/2311—Mounting the bubbling devices or the diffusers
- B01F23/23112—Mounting the bubbling devices or the diffusers comprising the use of flow guiding elements adjacent or above the gas stream
- B01F23/231121—Mounting the bubbling devices or the diffusers comprising the use of flow guiding elements adjacent or above the gas stream the flow guiding elements being baffles, tubes or walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/231—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids by bubbling
- B01F23/23105—Arrangement or manipulation of the gas bubbling devices
- B01F23/2312—Diffusers
- B01F23/23124—Diffusers consisting of flexible porous or perforated material, e.g. fabric
- B01F23/231245—Fabric in the form of woven, knitted, braided, non-woven or flocculated fibers or filaments
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/231—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids by bubbling
- B01F23/23105—Arrangement or manipulation of the gas bubbling devices
- B01F23/2312—Diffusers
- B01F23/23126—Diffusers characterised by the shape of the diffuser element
- B01F23/231266—Diffusers characterised by the shape of the diffuser element being in the form of rings or annular elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/233—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
- B01F23/2334—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements provided with stationary guiding means surrounding at least partially the stirrer
- B01F23/23341—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements provided with stationary guiding means surrounding at least partially the stirrer with tubes surrounding the stirrer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/233—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
- B01F23/2335—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the direction of introduction of the gas relative to the stirrer
- B01F23/23354—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the direction of introduction of the gas relative to the stirrer the gas being driven away from the rotating stirrer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/233—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements
- B01F23/2336—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the location of the place of introduction of the gas relative to the stirrer
- B01F23/23363—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids using driven stirrers with completely immersed stirring elements characterised by the location of the place of introduction of the gas relative to the stirrer the gas being introduced above the stirrer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/237—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids characterised by the physical or chemical properties of gases or vapours introduced in the liquid media
- B01F23/2376—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids characterised by the physical or chemical properties of gases or vapours introduced in the liquid media characterised by the gas being introduced
- B01F23/23761—Aerating, i.e. introducing oxygen containing gas in liquids
- B01F23/237612—Oxygen
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/80—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis
- B01F27/808—Mixers with rotary stirring devices in fixed receptacles; Kneaders with stirrers rotating about a substantially vertical axis with stirrers driven from the bottom of the receptacle
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
- B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
- B01F35/32—Driving arrangements
- B01F35/321—Disposition of the drive
- B01F35/3213—Disposition of the drive at the lower side of the axis, e.g. driving the stirrer from the bottom of a receptacle
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/16—Hollow fibers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F2025/93—Arrangements, nature or configuration of flow guiding elements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
- B01F2101/44—Mixing of ingredients for microbiology, enzymology, in vitro culture or genetic manipulation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
- B01F23/20—Mixing gases with liquids
- B01F23/23—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids
- B01F23/231—Mixing gases with liquids by introducing gases into liquid media, e.g. for producing aerated liquids by bubbling
- B01F23/23105—Arrangement or manipulation of the gas bubbling devices
- B01F23/2312—Diffusers
- B01F23/23123—Diffusers consisting of rigid porous or perforated material
- B01F23/231231—Diffusers consisting of rigid porous or perforated material the outlets being in the form of perforations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
- B01F27/05—Stirrers
- B01F27/11—Stirrers characterised by the configuration of the stirrers
- B01F27/113—Propeller-shaped stirrers for producing an axial flow, e.g. shaped like a ship or aircraft propeller
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/818—Aeration or oxygen transfer technique
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Sustainable Development (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Clinical Laboratory Science (AREA)
- Textile Engineering (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/328,629 US4960706A (en) | 1989-03-27 | 1989-03-27 | Static oxygenator for suspension culture of animal cells |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE130866T1 true ATE130866T1 (de) | 1995-12-15 |
Family
ID=23281732
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT90904984T ATE130866T1 (de) | 1989-03-27 | 1990-03-12 | Statischer oxygenator zur suspensionskultur von tierischen zellen. |
Country Status (8)
Country | Link |
---|---|
US (1) | US4960706A (de) |
EP (1) | EP0422149B1 (de) |
JP (1) | JPH03504926A (de) |
AT (1) | ATE130866T1 (de) |
CA (1) | CA2012320A1 (de) |
DE (1) | DE69023873T2 (de) |
DK (1) | DK0422149T3 (de) |
WO (1) | WO1990011347A1 (de) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5672507A (en) * | 1991-01-31 | 1997-09-30 | Boehringer Ingelheim Animal Health, Inc. | Apparatus for the surface culture of nucleated cells and cell culture dependent substances |
US5248613A (en) * | 1991-07-08 | 1993-09-28 | Roubicek Rudolf V | Nonhomogeneous centrifugal film bioreactor |
US5855775A (en) | 1995-05-05 | 1999-01-05 | Kerfoot; William B. | Microporous diffusion apparatus |
USRE43350E1 (en) | 1995-05-05 | 2012-05-08 | Think Village-Kerfoot, Llc | Microporous diffusion apparatus |
US5925293A (en) * | 1996-10-04 | 1999-07-20 | General Signal Corporation | Mixer sparging apparatus |
US6335191B1 (en) | 1998-02-27 | 2002-01-01 | Nch Corporation | Automated system and method for growing bacteria |
US5888391A (en) * | 1998-09-15 | 1999-03-30 | Sovmestnoe Rossysko-Ukrainskoe predpriyatie Obshestvo s ogranichennoi otvetstvennostju Nauchno--proizvodstvennaya firma Ecopolimer (OOO NPF "Ecopolimer") | Aerating device |
US6436285B1 (en) | 1999-12-22 | 2002-08-20 | William B. Kerfoot | Laminated microporous diffuser |
US6582611B1 (en) | 2000-07-06 | 2003-06-24 | William B. Kerfoot | Groundwater and subsurface remediation |
US8557110B2 (en) | 2000-07-06 | 2013-10-15 | Thinkvillage-Kerfoot, Llc | Groundwater and subsurface remediation |
US7666316B2 (en) | 2004-07-20 | 2010-02-23 | Thinkvillage-Kerfoot, Llc | Permanganate-coated ozone for groundwater and soil treatment with in-situ oxidation |
US7442313B2 (en) | 2003-08-27 | 2008-10-28 | Thinkvillage-Kerfoot, Llc | Environmental remediation method and system |
US8302939B2 (en) | 2003-02-12 | 2012-11-06 | Thinkvillage-Kerfoot, Llc | Soil and water remediation system and method |
US6913251B2 (en) | 2003-02-12 | 2005-07-05 | William B. Kerfoot | Deep well sparging |
AU2004280623B2 (en) | 2003-10-08 | 2010-12-02 | Wilson Wolf Manufacturing, LLC | Cell culture methods and devices utilizing gas permeable materials |
US7569140B2 (en) | 2005-11-10 | 2009-08-04 | Thinkvillage-Kerfoot, Llc | Directional spargewell system |
US7621696B2 (en) | 2006-07-12 | 2009-11-24 | Thinkvillage-Kerfoot, Llc | Directional microporous diffuser and directional sparging |
US7651611B2 (en) | 2006-07-12 | 2010-01-26 | Thinkvillage-Kerfoot, Llc | Directional microporous diffuser and directional sparging |
US7401767B2 (en) | 2003-12-24 | 2008-07-22 | Kerfoot William B | Directional microporous diffuser and directional sparging |
US8771507B2 (en) | 2003-12-24 | 2014-07-08 | Thinkvillage-Kerfoot, Llc | Directional microporous diffuser and directional sparging |
US7745209B2 (en) | 2005-07-26 | 2010-06-29 | Corning Incorporated | Multilayered cell culture apparatus |
DE102006008687A1 (de) * | 2006-02-24 | 2007-08-30 | Bayer Technology Services Gmbh | Verfahren und Vorrichtung zur Be- und Entgasung von Flüssigkeiten |
CN101611133A (zh) | 2006-12-07 | 2009-12-23 | 威尔森沃尔夫制造公司 | 高效装置及培养细胞的方法 |
US9868095B2 (en) | 2007-05-02 | 2018-01-16 | Finesse Solutions, Inc. | Disposable bioreactor system |
ATE556763T1 (de) * | 2008-03-19 | 2012-05-15 | Sartorius Stedim Biotech Gmbh | Mischgefäss |
EP2297295A4 (de) * | 2008-07-08 | 2013-11-27 | Wolf Wilson Mfg Corp | Verbesserte gasdurchlässige zellkulturvorrichtung und verfahren zu ihrer verwendung |
DE102008049120A1 (de) | 2008-09-26 | 2010-04-01 | Bayer Technology Services Gmbh | Verfahren zur Reduzierung von Ablagerungen bei der Kultivierung von Organismen |
FR2943355B1 (fr) * | 2009-03-18 | 2011-04-08 | Sartorius Stedim Biotech Sa | Recipient-melangeur avec palier d'arbre en partie superieure |
US8551762B2 (en) | 2009-07-07 | 2013-10-08 | Nch Corporation | System and apparatus for feeding, solubilizing, growing and discharging a biological material |
US8961893B2 (en) * | 2009-07-07 | 2015-02-24 | Nch Corporation | Automated chemical diluter system having disposable components |
DE102009042200A1 (de) | 2009-09-18 | 2011-04-14 | Bayer Technology Services Gmbh | Plattenbegaser |
US9694401B2 (en) | 2013-03-04 | 2017-07-04 | Kerfoot Technologies, Inc. | Method and apparatus for treating perfluoroalkyl compounds |
WO2015195636A1 (en) * | 2014-06-16 | 2015-12-23 | Siemens Healthcare Diagnostics Inc. | Fluidic device and degassing method |
US11141727B2 (en) | 2016-07-12 | 2021-10-12 | EMULATE, Inc. | Removing bubbles in a microfluidic device |
CN110935355A (zh) * | 2019-12-11 | 2020-03-31 | 杨昌瑞 | 一种奶制品加工用均质混合设备 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4087327A (en) * | 1976-04-12 | 1978-05-02 | Monsanto Company | Mammalion cell culture process |
US4264739A (en) * | 1979-01-05 | 1981-04-28 | Merck & Co., Inc. | Sparger for cell culture system |
CH651587A5 (de) * | 1980-11-18 | 1985-09-30 | Chemap Ag | Verfahren und vorrichtung zur submersen zuechtung von zellkulturen. |
DE3047101A1 (de) * | 1980-12-13 | 1982-07-22 | Hoechst Ag, 6000 Frankfurt | Verfahren zum verbessern der gasverteilung in mammut-schlaufenreaktoren |
CH647547A5 (de) * | 1982-02-12 | 1985-01-31 | Chemap Ag | Verfahren und vorrichtung zum zuechten von mikroorganismen. |
CH663422A5 (de) * | 1982-05-27 | 1987-12-15 | Chemap Ag | Verfahren und fermenter zur zuechtung von gewebezellen. |
GB2122333B (en) * | 1982-06-15 | 1985-08-14 | Rolls Royce | Improvements in or relating to dual fuel burners for gas turbine engines |
US4668632A (en) * | 1985-02-06 | 1987-05-26 | Vxr, Inc. | Sparger and apparatus for and method of growing cells |
US4727040A (en) * | 1985-03-01 | 1988-02-23 | New Brunswick Scientific Co., Ltd. | Sparger for fermentation and tissue culturing vessels |
US4649117A (en) * | 1985-03-15 | 1987-03-10 | Hoffmann-La Roche Inc. | Air lift bioreactor |
GB8515629D0 (en) * | 1985-06-20 | 1985-07-24 | Celltech Ltd | Fermenter |
SU1308623A1 (ru) * | 1985-07-23 | 1987-05-07 | Всесоюзный научно-исследовательский институт ветеринарной вирусологии и микробиологии | Аппарат дл культивировани клеток или вирусов на микроносител х |
DE3535183A1 (de) * | 1985-10-02 | 1987-04-16 | Biotechnolog Forschung Gmbh | Vorrichtung und verfahren zur blasenfreien begasung von fluessigkeiten, insbesondere von kulturmedien zur vermehrung von gewebekulturen |
-
1989
- 1989-03-27 US US07/328,629 patent/US4960706A/en not_active Expired - Lifetime
-
1990
- 1990-03-12 DK DK90904984.3T patent/DK0422149T3/da active
- 1990-03-12 WO PCT/US1990/001332 patent/WO1990011347A1/en active IP Right Grant
- 1990-03-12 DE DE69023873T patent/DE69023873T2/de not_active Expired - Fee Related
- 1990-03-12 AT AT90904984T patent/ATE130866T1/de not_active IP Right Cessation
- 1990-03-12 EP EP90904984A patent/EP0422149B1/de not_active Expired - Lifetime
- 1990-03-12 JP JP2505090A patent/JPH03504926A/ja active Pending
- 1990-03-15 CA CA002012320A patent/CA2012320A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69023873D1 (de) | 1996-01-11 |
EP0422149A4 (en) | 1992-01-02 |
EP0422149B1 (de) | 1995-11-29 |
JPH03504926A (ja) | 1991-10-31 |
WO1990011347A1 (en) | 1990-10-04 |
EP0422149A1 (de) | 1991-04-17 |
CA2012320A1 (en) | 1990-09-27 |
DE69023873T2 (de) | 1996-06-20 |
US4960706A (en) | 1990-10-02 |
DK0422149T3 (da) | 1995-12-27 |
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