ATE129254T1 - Antientzündungsmittel und zusammensetzungen. - Google Patents
Antientzündungsmittel und zusammensetzungen.Info
- Publication number
- ATE129254T1 ATE129254T1 AT88902773T AT88902773T ATE129254T1 AT E129254 T1 ATE129254 T1 AT E129254T1 AT 88902773 T AT88902773 T AT 88902773T AT 88902773 T AT88902773 T AT 88902773T AT E129254 T1 ATE129254 T1 AT E129254T1
- Authority
- AT
- Austria
- Prior art keywords
- compositions
- inflammatory agents
- polysulfate
- xylan
- derivatives
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 229940121363 anti-inflammatory agent Drugs 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 title 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 229920001221 xylan Polymers 0.000 abstract 1
- 150000004823 xylans Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0057—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Xylans, i.e. xylosaccharide, e.g. arabinoxylan, arabinofuronan, pentosans; (beta-1,3)(beta-1,4)-D-Xylans, e.g. rhodymenans; Hemicellulose; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPI095187 | 1987-03-19 | ||
AUPI247887 | 1987-06-15 | ||
AUPI581987 | 1987-12-09 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE129254T1 true ATE129254T1 (de) | 1995-11-15 |
Family
ID=27157350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT88902773T ATE129254T1 (de) | 1987-03-19 | 1988-03-21 | Antientzündungsmittel und zusammensetzungen. |
Country Status (8)
Country | Link |
---|---|
US (2) | US5145841A (de) |
EP (1) | EP0356435B1 (de) |
JP (1) | JP2511829B2 (de) |
AT (1) | ATE129254T1 (de) |
AU (1) | AU604542B2 (de) |
CA (1) | CA1327354C (de) |
DE (1) | DE3854604T2 (de) |
WO (1) | WO1988007060A1 (de) |
Families Citing this family (70)
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IL85145A (en) * | 1987-01-23 | 1994-08-26 | Univ Australian | Anti-metastatic pharmacological or veterinary preparations containing modified herpin with reduced anticoagulant activity |
US4931553A (en) * | 1988-05-11 | 1990-06-05 | Gill Devinder S | Platinum-polymer complexes and their use as antitumor agents |
US5043438B1 (en) * | 1989-02-16 | 1998-04-28 | Lever Brothers Ltd | Process for the synthesis of polyol fatty-acid esters |
HU203372B (en) * | 1989-02-24 | 1991-07-29 | Richter Gedeon Vegyeszet | Process for producing hyaluronic associates and pharmaceutical compositions and cosmetics comprising such active ingredient |
CA1340994C (en) * | 1989-09-21 | 2000-05-16 | Rudolf Edgar Dr. Falk | Treatment of conditions and disease |
JP2945993B2 (ja) * | 1989-12-05 | 1999-09-06 | 武田薬品工業株式会社 | 外用剤 |
US5095037B1 (en) * | 1989-12-21 | 1995-12-19 | Nissho Kk | Combined anti-inflammatory agent |
IT1240316B (it) * | 1990-02-21 | 1993-12-07 | Ricerca Di Schiena Del Dr. Michele G. Di Schiema & C. | Composizioni a base di acido ialuronico ad alto peso molecolare somministrabili per via topica per il trattamento di infiammazioni del cavo orale ,per la cosmetica e l'igiene del cavo orale |
IT1240744B (it) * | 1990-04-05 | 1993-12-17 | Bioindustria Spa | Complessi di condroitinsolfato ad azione antiinfiammatoria |
US5990096A (en) * | 1990-09-18 | 1999-11-23 | Hyal Pharmaceutical Corporation | Formulations containing hyaluronic acid |
US5824658A (en) * | 1990-09-18 | 1998-10-20 | Hyal Pharmaceutical Corporation | Topical composition containing hyaluronic acid and NSAIDS |
CA2061703C (en) * | 1992-02-20 | 2002-07-02 | Rudolf E. Falk | Formulations containing hyaluronic acid |
US5639738A (en) * | 1992-02-20 | 1997-06-17 | Hyal Pharmaceutical Corporation | Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic acid and NSAIDs |
US5910489A (en) * | 1990-09-18 | 1999-06-08 | Hyal Pharmaceutical Corporation | Topical composition containing hyaluronic acid and NSAIDS |
US5514667A (en) * | 1990-11-05 | 1996-05-07 | Arthropharm Pty. Limited | Method for topical treatment of herpes infections |
ATE138939T1 (de) * | 1991-01-30 | 1996-06-15 | Hoechst Ag | Niedermolekulare sulfatierte poly--g(b)-2,6- fructofuranosane und deren verwendung zur behandlung von degenerativen gelenkerkrankungen |
AU1154992A (en) * | 1991-01-30 | 1992-09-07 | Hoechst Aktiengesellschaft | Use of substituted polysaccharides for the treatment of degenerative articular ailments |
AU1052492A (en) * | 1991-01-31 | 1992-08-06 | Farmitalia Carlo Erba S.R.L. | Synergistic composition comprising a fibroblast growth factor and a sulfated polylsaccharide, for use as antiviral agent |
US6103704A (en) * | 1991-07-03 | 2000-08-15 | Hyal Pharmaceutical Corporation | Therapeutic methods using hyaluronic acid |
US6022866A (en) * | 1991-07-03 | 2000-02-08 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
US5792753A (en) * | 1991-07-03 | 1998-08-11 | Hyal Pharmaceutical Corporation | Compositions comprising hyaluronic acid and prostaglandin-synthesis-inhibiting drugs |
US5977088A (en) * | 1991-07-03 | 1999-11-02 | Hyal Pharmaceutical Corporation | Formulations containing hyaluronic acid |
US5990095A (en) * | 1991-07-03 | 1999-11-23 | Hyal Pharmaceutical Corporation | Use of hyaluronic acid and forms to prevent arterial restenosis |
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US6147059A (en) * | 1992-02-20 | 2000-11-14 | Hyal Pharmaceutical Corporation | Formulations containing hyaluronic acid |
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US6218373B1 (en) | 1992-02-20 | 2001-04-17 | Hyal Pharmaceutical Corporation | Formulations containing hyaluronic acid |
US6114314A (en) * | 1992-02-21 | 2000-09-05 | Hyal Pharmaceutical Corp. | Formulations containing hyaluronic acid |
US5767106A (en) * | 1992-02-21 | 1998-06-16 | Hyal Pharmaceutical Corporation | Treatment of disease and conditions associated with macrophage infiltration |
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JP4027973B2 (ja) * | 1995-09-19 | 2007-12-26 | 生化学工業株式会社 | 抗炎症剤 |
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US5866554A (en) * | 1996-07-19 | 1999-02-02 | Shalaby; Shalaby W. | Compositions for prevention of inflammation and adhesion formation and uses thereof |
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US7067144B2 (en) * | 1998-10-20 | 2006-06-27 | Omeros Corporation | Compositions and methods for systemic inhibition of cartilage degradation |
JP4607264B2 (ja) * | 1998-12-01 | 2011-01-05 | 生化学工業株式会社 | ヒアルロン酸を有効成分とする異所性石灰化抑制剤 |
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US6608042B2 (en) * | 2000-03-28 | 2003-08-19 | Aventis Pharma, S.A. | Pharmaceutical compositions containing oligosaccharides, the novel oligosaccharides and preparation thereof |
DE10053053A1 (de) * | 2000-10-19 | 2002-05-16 | Knoell Hans Forschung Ev | Pharmazeutische Formulierungen zur Hemmung von entzündlichen Arthritiden |
DE10054257A1 (de) * | 2000-11-02 | 2002-05-16 | Kief Horst | Heilmittel zur Intraarticulären Injektion |
US6593310B1 (en) * | 2000-11-21 | 2003-07-15 | Arthropharm Pty. Ltd. | Treatment of osteoporosis |
DE10141106A1 (de) * | 2001-08-22 | 2003-03-13 | Aventis Pharma Gmbh | Verwendung von Heparinoid-Derivaten zur Behandlung und Diagnose von mit Heparinoiden behandelbaren Erkrankungen |
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CA2616230A1 (en) * | 2005-07-22 | 2007-02-01 | Trf Pharma, Inc. | Method for treating sickle cell disease and sickle cell disease sequelae |
NZ571537A (en) | 2006-04-03 | 2012-06-29 | Nutramax Lab Inc | Stabilized pentosan polysulfate (PPS) formulations and methods of analayzing them |
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US20080076723A1 (en) * | 2006-09-27 | 2008-03-27 | Sylvan Pharmaceuticals Pty Ltd. | Inhibition of cathepsin K activity and the treatment and prevention of disease |
AU2013234396B2 (en) * | 2007-12-04 | 2014-09-11 | Proteobioactives Pty Ltd | Protection of progenitor cells and regulation of their differentiation |
KR101995016B1 (ko) | 2007-12-04 | 2019-06-28 | 프로테오바이오엑티브스 피티와이 엘티디 | 전구 세포의 보호 및 그의 분화 조절 |
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WO2012027797A1 (en) * | 2010-09-02 | 2012-03-08 | David Charles James | Anti-inflammatory compostion |
WO2012114349A1 (en) * | 2011-02-23 | 2012-08-30 | Cadila Healthcare Limited | An improved process for the preparation of pentosan polysulfate sodium |
BR112018074235A2 (pt) | 2016-05-26 | 2019-03-06 | Griffith University | tratamento da inflamação induzida por alfavírus |
KR102075596B1 (ko) * | 2017-12-04 | 2020-02-10 | 이일훈 | 덱스트란 또는 폴록사머를 포함하는 관절 질환 또는 결체조직 질환 치료용 조성물 |
GB2574944B (en) | 2018-02-16 | 2021-03-03 | Proteobioactives Pty Ltd | Methods and compositions for the treatment of pain and/or inflammation |
EP3791884A1 (de) | 2019-09-16 | 2021-03-17 | Oskar Bunz | Kombination aus heparin und magnesiumsalz zur behandlung viraler infektionen |
CN111001041B (zh) * | 2019-12-10 | 2022-02-01 | 河南亚都实业有限公司 | 一种抗炎抗菌复合皮肤支架材料及制备方法 |
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SE453394B (sv) * | 1986-07-07 | 1988-02-01 | Pharmacia Ab | Forfarande for framstellning av sulfaterade polysackarider genom anvendning av ett reducerande medel for sulfateringsreaktionen |
SE8702254D0 (sv) * | 1987-05-29 | 1987-05-29 | Kabivitrum Ab | Novel heparin derivatives |
MC2098A1 (fr) * | 1988-06-03 | 1991-02-15 | Italfarmaco Spa | Sels de glycosaminoglycanes,procedes pour leur preparation et compositions pharmaceutiques les contenant |
-
1988
- 1988-03-21 EP EP88902773A patent/EP0356435B1/de not_active Expired - Lifetime
- 1988-03-21 AT AT88902773T patent/ATE129254T1/de not_active IP Right Cessation
- 1988-03-21 JP JP63502869A patent/JP2511829B2/ja not_active Expired - Lifetime
- 1988-03-21 CA CA000561945A patent/CA1327354C/en not_active Expired - Lifetime
- 1988-03-21 US US07/423,455 patent/US5145841A/en not_active Expired - Lifetime
- 1988-03-21 WO PCT/AU1988/000077 patent/WO1988007060A1/en active IP Right Grant
- 1988-03-21 AU AU15456/88A patent/AU604542B2/en not_active Ceased
- 1988-03-21 DE DE3854604T patent/DE3854604T2/de not_active Expired - Lifetime
-
1992
- 1992-06-10 US US07/903,081 patent/US5470840A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU1545688A (en) | 1988-10-10 |
DE3854604D1 (de) | 1995-11-23 |
JPH02502547A (ja) | 1990-08-16 |
AU604542B2 (en) | 1990-12-20 |
EP0356435B1 (de) | 1995-10-18 |
EP0356435A4 (de) | 1990-06-26 |
EP0356435A1 (de) | 1990-03-07 |
DE3854604T2 (de) | 1996-03-28 |
JP2511829B2 (ja) | 1996-07-03 |
US5470840A (en) | 1995-11-28 |
CA1327354C (en) | 1994-03-01 |
US5145841A (en) | 1992-09-08 |
WO1988007060A1 (en) | 1988-09-22 |
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Legal Events
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UEP | Publication of translation of european patent specification | ||
REN | Ceased due to non-payment of the annual fee |