ATE129153T1 - Verwendung von chinolizin- und chinolizinon- derivaten zur herstellung von arzneimitteln. - Google Patents
Verwendung von chinolizin- und chinolizinon- derivaten zur herstellung von arzneimitteln.Info
- Publication number
- ATE129153T1 ATE129153T1 AT89100392T AT89100392T ATE129153T1 AT E129153 T1 ATE129153 T1 AT E129153T1 AT 89100392 T AT89100392 T AT 89100392T AT 89100392 T AT89100392 T AT 89100392T AT E129153 T1 ATE129153 T1 AT E129153T1
- Authority
- AT
- Austria
- Prior art keywords
- quinolicin
- production
- quinolizinone
- medicinal products
- derivatives
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- GDRVFDDBLLKWRI-UHFFFAOYSA-N 4H-quinolizine Chemical compound C1=CC=CN2CC=CC=C21 GDRVFDDBLLKWRI-UHFFFAOYSA-N 0.000 abstract 1
- 208000019901 Anxiety disease Diseases 0.000 abstract 1
- 208000010412 Glaucoma Diseases 0.000 abstract 1
- 208000019695 Migraine disease Diseases 0.000 abstract 1
- 208000028017 Psychotic disease Diseases 0.000 abstract 1
- 206010047700 Vomiting Diseases 0.000 abstract 1
- 230000036506 anxiety Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 230000030135 gastric motility Effects 0.000 abstract 1
- 206010027599 migraine Diseases 0.000 abstract 1
- 150000003250 quinolizines Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/18—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Anesthesiology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Nutrition Science (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP88400416A EP0329903A1 (de) | 1988-02-23 | 1988-02-23 | Verwendung von Chinolizinon- und Chinolizin-Derivaten zur Herstellung von Arzneimitteln zur Behandlung von Glaukom |
| EP88400415A EP0329902A1 (de) | 1988-02-23 | 1988-02-23 | Verwendung von Chinolizinon- und Chinolizin-Derivaten zur Herstellung von Arzneimitteln zur Behandlung von Psychose |
| EP88400418A EP0329905A1 (de) | 1988-02-23 | 1988-02-23 | Verwendung von Chinolizin- und Chinolizinon-Derivaten zur Herstellung von Arzneimitteln zur Erhöhung der Magenbeweglichkeit |
| EP88400417A EP0329904A1 (de) | 1988-02-23 | 1988-02-23 | Verwendung von Chinolizin- und Chinolizinon-Derivaten zur Herstellung von Arzneimitteln zur Behandlung von Anxietas |
| US18563188A | 1988-04-26 | 1988-04-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE129153T1 true ATE129153T1 (de) | 1995-11-15 |
Family
ID=27513624
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89100392T ATE129153T1 (de) | 1988-02-23 | 1989-01-11 | Verwendung von chinolizin- und chinolizinon- derivaten zur herstellung von arzneimitteln. |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0329932B1 (de) |
| JP (1) | JPH02288880A (de) |
| KR (1) | KR890013018A (de) |
| AT (1) | ATE129153T1 (de) |
| AU (1) | AU624115B2 (de) |
| DE (1) | DE68924545T2 (de) |
| DK (1) | DK175643B1 (de) |
| ES (1) | ES2080727T3 (de) |
| GR (1) | GR3018299T3 (de) |
| IE (1) | IE72504B1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE97803T1 (de) * | 1989-04-21 | 1993-12-15 | Sandoz Ag | Therapeutische verwendung von 5-ht3-rezeptorantagonisten. |
| EP0492020A1 (de) * | 1990-12-21 | 1992-07-01 | Merrell Dow Pharmaceuticals Inc. | Verwendung von bestimmten Estern von Hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3(4H)-on und verwandter Verbindungen zur Behandlung von kognitiven Erkrankungen |
| AU675060B2 (en) * | 1992-02-24 | 1997-01-23 | Aventisub Ii Inc. | 2,6-methano-2H-quinolizin derivative as 5-HT3-receptor antagonist |
| US5508287A (en) * | 1992-02-24 | 1996-04-16 | Merrell Pharmaceuticals Inc. | 2,6-methano-2H-quinolizin derivative as 5-HT3 -receptor antagonist |
| ES2363998T3 (es) * | 2007-03-23 | 2011-08-22 | Abbott Laboratories | Derivados ester y carbamato de azaadamantano y métodos de uso de los mismos. |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI74707C (fi) * | 1982-06-29 | 1988-03-10 | Sandoz Ag | Foerfarande foer framstaellning av terapeutiskt anvaendbara alkylenoeverbryggade piperidylestrar eller -amider av bicykliska karboxylsyror. |
| WO1985001048A1 (en) * | 1983-08-26 | 1985-03-14 | Sandoz Ag | Aromatic esters or amides of carboxylic acid and sulfonic acid |
| DE3445377A1 (de) * | 1983-12-23 | 1985-07-04 | Sandoz-Patent-GmbH, 7850 Lörrach | Carbocylische und heterocyclische carbonsaeureester und -amide von ueberbrueckten und nicht ueberbrueckten cyclischen stickstoffhaltigen aminen oder alkoholen |
| AU583343B2 (en) * | 1985-01-23 | 1989-04-27 | Glaxo Group Limited | Heterocyclic compounds |
| DE385517T1 (de) * | 1985-03-14 | 1991-07-25 | Beecham Group p.l.c., Brentford, Middlesex | Arzneimittel zur behandlung von erbrechen. |
| GB8525913D0 (en) * | 1985-10-21 | 1985-11-27 | Beecham Group Plc | Compounds |
| GB8511988D0 (en) * | 1985-05-11 | 1985-06-19 | Beecham Group Plc | Compounds |
| GB8520616D0 (en) * | 1985-08-16 | 1985-09-25 | Beecham Group Plc | Compounds |
| GB8523211D0 (en) * | 1985-09-19 | 1985-10-23 | Beecham Group Plc | Compounds |
| EP0220011A3 (de) * | 1985-10-12 | 1990-01-03 | Beecham Group Plc | Verwendung von Azabicycloalkylbenzamiden zur Behandlung von Magen-Darmbewegungskrankheiten, Migräne, Emesis, Migränekopfschmerzen, Trigeminusneuralgie und Arhythmie |
| US4910193A (en) * | 1985-12-16 | 1990-03-20 | Sandoz Ltd. | Treatment of gastrointestinal disorders |
| ZA878096B (en) * | 1986-11-03 | 1988-04-26 | Merrell Dow Pharmaceuticals Inc. | Esters of hexahydro-8-hydroxy-2,6-methano-2h-quinolizin-3(4h)-one and related compounds |
| EP0330788A1 (de) * | 1988-03-01 | 1989-09-06 | Merrell Dow Pharmaceuticals Inc. | Verwendung von Chinolizin- und Chinolizinon-Derivaten zur Herstellung von Arzneimitteln zur Behandlung von Herz-Arrhythmie |
-
1989
- 1989-01-11 EP EP89100392A patent/EP0329932B1/de not_active Expired - Lifetime
- 1989-01-11 DE DE68924545T patent/DE68924545T2/de not_active Expired - Lifetime
- 1989-01-11 ES ES89100392T patent/ES2080727T3/es not_active Expired - Lifetime
- 1989-01-11 AT AT89100392T patent/ATE129153T1/de not_active IP Right Cessation
- 1989-02-22 KR KR1019890002061A patent/KR890013018A/ko not_active Ceased
- 1989-02-22 DK DK198900809A patent/DK175643B1/da not_active IP Right Cessation
- 1989-02-22 IE IE56489A patent/IE72504B1/en not_active IP Right Cessation
- 1989-02-22 AU AU30214/89A patent/AU624115B2/en not_active Expired
- 1989-02-23 JP JP1042012A patent/JPH02288880A/ja active Pending
-
1995
- 1995-12-05 GR GR950403417T patent/GR3018299T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE68924545T2 (de) | 1996-03-21 |
| EP0329932B1 (de) | 1995-10-18 |
| AU3021489A (en) | 1989-08-24 |
| KR890013018A (ko) | 1989-09-20 |
| DK80989D0 (da) | 1989-02-22 |
| DK80989A (da) | 1989-08-24 |
| EP0329932A2 (de) | 1989-08-30 |
| IE72504B1 (en) | 1997-04-23 |
| EP0329932A3 (de) | 1992-08-05 |
| DK175643B1 (da) | 2005-01-03 |
| AU624115B2 (en) | 1992-06-04 |
| GR3018299T3 (en) | 1996-03-31 |
| JPH02288880A (ja) | 1990-11-28 |
| ES2080727T3 (es) | 1996-02-16 |
| IE890564L (en) | 1989-08-23 |
| DE68924545D1 (de) | 1995-11-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEFA | Change of the company name | ||
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |